المؤلفون: Axell E; Biochemistry and Structural Biology, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden., Hu J; Division of Physical Chemistry, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden., Lindberg M; Biochemistry and Structural Biology, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden., Dear AJ; Biochemistry and Structural Biology, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden.; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, CB2 1EW Cambridge, United Kingdom., Ortigosa-Pascual L; Biochemistry and Structural Biology, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden., Andrzejewska EA; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, CB2 1EW Cambridge, United Kingdom., Šneiderienė G; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, CB2 1EW Cambridge, United Kingdom., Thacker D; Biochemistry and Structural Biology, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden., Knowles TPJ; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, CB2 1EW Cambridge, United Kingdom., Sparr E; Division of Physical Chemistry, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden., Linse S; Biochemistry and Structural Biology, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jun 18; Vol. 121 (25), pp. e2322572121. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid*/metabolism , Amyloid*/chemistry, Kinetics ; Humans ; Shear Strength ; Protein Aggregates ; Peptides/chemistry ; Peptides/metabolism ; Alzheimer Disease/metabolism

المؤلفون: Dear AJ; Biochemistry and Structural Biology, Lund University, Lund 221 00, Sweden.; Centre for Misfolding Diseases Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K., Thacker D; Biochemistry and Structural Biology, Lund University, Lund 221 00, Sweden., Wennmalm S; Department of Applied Physics, Biophysics Group, SciLifeLab, Royal Institute of Technology-KTH, Solna 171 65, Sweden., Ortigosa-Pascual L; Biochemistry and Structural Biology, Lund University, Lund 221 00, Sweden., Andrzejewska EA; Centre for Misfolding Diseases Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K., Meisl G; Centre for Misfolding Diseases Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K., Linse S; Biochemistry and Structural Biology, Lund University, Lund 221 00, Sweden., Knowles TPJ; Centre for Misfolding Diseases Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.; Cavendish Laboratory, University of Cambridge, J J Thomson Avenue, Cambridge CB3 0HE, U.K.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Jun 05; Vol. 15 (11), pp. 2296-2307. Date of Electronic Publication: 2024 May 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/metabolism , Amyloid beta-Peptides*/chemistry , Peptide Fragments*/chemistry , Peptide Fragments*/metabolism, Humans ; Amyloid/metabolism ; Amyloid/chemistry ; Alzheimer Disease/metabolism ; Kinetics

المؤلفون: Dear AJ; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Garcia GA; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Meisl G; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Collins GA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.; Department of Biochemistry, Molecular Biology, Entomology & Plant Pathology, Mississippi State University, Starkville, MS 39762., Knowles TPJ; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, United Kingdom., Goldberg AL; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 30; Vol. 121 (18), pp. e2313107121. Date of Electronic Publication: 2024 Apr 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Entropy* , Proteome*/metabolism , Proteolysis*, Humans ; Animals ; Bayes Theorem ; Proteostasis ; Kinetics ; Cyclic AMP/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Cyclic GMP/metabolism

المؤلفون: Dear AJ; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Teng X; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Ball SR; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Lewin J; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Horne RI; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Clow D; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Stevenson A; Department of Biology, Institute of Biochemistry, ETH Zurich Otto Stern Weg 3 8093 Zurich Switzerland.; Bringing Materials to Life Initiative, ETH Zurich Switzerland., Harper N; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Yahya K; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Yang X; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Brewerton SC; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Thomson J; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Michaels TCT; Department of Biology, Institute of Biochemistry, ETH Zurich Otto Stern Weg 3 8093 Zurich Switzerland.; Bringing Materials to Life Initiative, ETH Zurich Switzerland., Linse S; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com.; Biochemistry and Structural Biology, Lund University Lund Sweden., Knowles TPJ; Yusuf Hamied Department of Chemistry, University of Cambridge Cambridge UK.; Cavendish Laboratory, University of Cambridge Cambridge UK., Habchi J; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Meisl G; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com.

المصدر: Chemical science [Chem Sci] 2024 Apr 22; Vol. 15 (19), pp. 7229-7242. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

المؤلفون: Thacker D; Department of Biochemistry and Structural Biology, Lund University, Lund22362, Sweden., Willas A; Department of Biochemistry and Structural Biology, Lund University, Lund22362, Sweden., Dear AJ; Department of Biochemistry and Structural Biology, Lund University, Lund22362, Sweden.; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, CambridgeCB2 1EW, U.K., Linse S; Department of Biochemistry and Structural Biology, Lund University, Lund22362, Sweden.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Dec 07; Vol. 13 (23), pp. 3477-3487. Date of Electronic Publication: 2022 Nov 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/genetics

المؤلفون: Michaels TCT; Department of Physics and Astronomy, Institute for the Physics of Living Systems, University College London, London, United Kingdom., Dear AJ; Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA., Cohen SIA; Department of Physics and Astronomy, Institute for the Physics of Living Systems, University College London, London, United Kingdom., Vendruscolo M; Yusuf Hamied Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Knowles TPJ; Yusuf Hamied Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.

المصدر: The Journal of chemical physics [J Chem Phys] 2022 Apr 28; Vol. 156 (16), pp. 164904.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Institute of Physics Country of Publication: United States NLM ID: 0375360 Publication Model: Print Cited Medium: Internet ISSN: 1089-7690 (Electronic) Linking ISSN: 00219606 NLM ISO Abbreviation: J Chem Phys Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid*/metabolism , Neurodegenerative Diseases*, Amyloidogenic Proteins ; Humans ; Kinetics

المؤلفون: Braun GA; Biochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se., Dear AJ; Biochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se.; Department of Cell Biology, Harvard Medical School Boston MA USA.; Paulson School of Engineering and Applied Science, Harvard University Cambridge MA USA.; Department of Chemistry, University of Cambridge Cambridge UK., Sanagavarapu K; Biochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital Mölndal Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology Queen Square London UK.; UK Dementia Research Institute at UCL London UK., Linse S; Biochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se.

المصدر: Chemical science [Chem Sci] 2022 Feb 07; Vol. 13 (8), pp. 2423-2439. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

المؤلفون: Dear AJ; School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA., Michaels TCT; School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA., Knowles TPJ; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Mahadevan L; School of Engineering and Applied Sciences, Department of Physics, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

المصدر: The Journal of chemical physics [J Chem Phys] 2021 Aug 14; Vol. 155 (6), pp. 064102.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Institute of Physics Country of Publication: United States NLM ID: 0375360 Publication Model: Print Cited Medium: Internet ISSN: 1089-7690 (Electronic) Linking ISSN: 00219606 NLM ISO Abbreviation: J Chem Phys Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid/*antagonists & inhibitors, Amyloid/metabolism ; Feedback ; Humans ; Kinetics ; Protein Aggregates/drug effects ; Stochastic Processes

المؤلفون: Zurlo E; Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands., Kumar P; Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands., Meisl G; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, United Kingdom., Dear AJ; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, United Kingdom., Mondal D; Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands., Claessens MMAE; Nanobiophysics Group, Department of Science and Technology, University Twente, Enschede, The Netherlands., Knowles TPJ; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, United Kingdom.; Cavendish Laboratory, University of Cambridge, Cambridge, United Kingdom., Huber M; Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands.

المصدر: PloS one [PLoS One] 2021 Jan 22; Vol. 16 (1), pp. e0245548. Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Protein Aggregates* , Protein Multimerization*, alpha-Synuclein/*chemistry, Kinetics ; Protein Structure, Quaternary

المؤلفون: Braun GA; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States.; Department of Biochemistry and Structural Biology, Centre for Molecular Protein Science, Lund University, Lund SE-22100, Sweden., Ary BE; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States., Dear AJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.; Paulson School of Engineering and Applied Science, Harvard University, Cambridge, Massachusetts 02138, United States., Rohn MCH; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States., Payson AM; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States., Lee DSM; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States., Parry RC; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States., Friedman C; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States., Knowles TPJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.; Cavendish Laboratory, University of Cambridge, J J Thomson Avenue, Cambridge CB3 0HE, U.K., Linse S; Department of Biochemistry and Structural Biology, Centre for Molecular Protein Science, Lund University, Lund SE-22100, Sweden., Åkerfeldt KS; Department of Chemistry, Haverford College, Haverford, Pennsylvania 19041, United States.

المصدر: Biomacromolecules [Biomacromolecules] 2020 Dec 14; Vol. 21 (12), pp. 4781-4794. Date of Electronic Publication: 2020 Nov 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100892849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4602 (Electronic) Linking ISSN: 15257797 NLM ISO Abbreviation: Biomacromolecules Subsets: MEDLINE

مواضيع طبية MeSH: Hydrogels* , Peptides*, Kinetics