المؤلفون: Weng Q; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Wan L; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Straker GC; Department of Biology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada., Deegan TD; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, UK DD1 5EH, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Duncker BP; Department of Biology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada., Neiman AM; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Luk E; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Hollingsworth NM; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.

المصدر: Genetics [Genetics] 2024 Jul 09. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-2631 (Electronic) Linking ISSN: 00166731 NLM ISO Abbreviation: Genetics Subsets: MEDLINE

المؤلفون: Raimi OG; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Ojha H; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Ehses K; Institute of Neuropathology, University Medical Center Göttingen, 37099 Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Dederer V; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Institute of Pharmaceutical Chemistry, Goethe-Universität, 60438 Frankfurt, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Goethe-Universität, 60438 Frankfurt, Germany., Lange SM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Rivera CP; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Deegan TD; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK., Chen Y; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Wightman M; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Toth R; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Labib KPM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Mathea S; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Institute of Pharmaceutical Chemistry, Goethe-Universität, 60438 Frankfurt, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Goethe-Universität, 60438 Frankfurt, Germany., Ranson N; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Fernández-Busnadiego R; Institute of Neuropathology, University Medical Center Göttingen, 37099 Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Faculty of Physics, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany., Muqit MMK; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.

المصدر: Science advances [Sci Adv] 2024 Jun 07; Vol. 10 (23), pp. eadn7191. Date of Electronic Publication: 2024 Jun 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Protein Kinases*/metabolism , Protein Kinases*/genetics , Mitochondrial Precursor Protein Import Complex Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics, Humans ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Mitochondria/metabolism ; Protein Binding ; Enzyme Activation ; Models, Molecular ; Protein Subunits/metabolism ; Protein Subunits/genetics

المؤلفون: Weng Q; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Wan L; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Straker GC; Department of Biology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada., Deegan TD; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, UK DD1 5EH, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Duncker BP; Department of Biology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada., Neiman AM; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Luk E; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA., Hollingsworth NM; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 25. Date of Electronic Publication: 2024 May 25.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Polo Rivera C; Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Deegan TD; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK. Electronic address: tdeegan@ed.ac.uk.

المصدر: Trends in genetics : TIG [Trends Genet] 2022 Oct; Vol. 38 (10), pp. 987-988. Date of Electronic Publication: 2022 May 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Comment

بيانات الدورية: Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 8507085 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0168-9525 (Print) Linking ISSN: 01689525 NLM ISO Abbreviation: Trends Genet Subsets: MEDLINE

مواضيع طبية MeSH: DNA Replication* , Replicon*/genetics, DNA ; DNA Helicases/metabolism

المؤلفون: Jenkyn-Bedford M; MRC Laboratory of Molecular Biology, Cambridge, UK., Jones ML; MRC Laboratory of Molecular Biology, Cambridge, UK., Baris Y; MRC Laboratory of Molecular Biology, Cambridge, UK., Labib KPM; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, UK., Cannone G; MRC Laboratory of Molecular Biology, Cambridge, UK., Yeeles JTP; MRC Laboratory of Molecular Biology, Cambridge, UK. jyeeles@mrc-lmb.cam.ac.uk., Deegan TD; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, UK. tdeegan@ed.ac.uk.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK. tdeegan@ed.ac.uk.

المصدر: Nature [Nature] 2021 Dec; Vol. 600 (7890), pp. 743-747. Date of Electronic Publication: 2021 Oct 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: DNA Replication* , Eukaryota*/genetics, Cryoelectron Microscopy ; DNA/metabolism ; DNA Helicases/metabolism ; Humans ; Ubiquitin-Protein Ligases/metabolism

المؤلفون: Xia Y; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Fujisawa R; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Deegan TD; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Sonneville R; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Labib KPM; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.

المصدر: The EMBO journal [EMBO J] 2021 Sep 01; Vol. 40 (17), pp. e108053. Date of Electronic Publication: 2021 Jul 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

مواضيع طبية MeSH: DNA Replication*, Caenorhabditis elegans Proteins/*metabolism , Carrier Proteins/*metabolism , DNA-Directed DNA Polymerase/*metabolism , Multienzyme Complexes/*metabolism, Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Carrier Proteins/genetics ; Cullin Proteins/genetics ; Cullin Proteins/metabolism ; Synthetic Lethal Mutations

المؤلفون: Canal B; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Fujisawa R; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., McClure AW; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Deegan TD; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Wu M; High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Ulferts R; Cell Biology of Infection Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Weissmann F; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Drury LS; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Bertolin AP; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Zeng J; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Beale R; Cell Biology of Infection Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Howell M; High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Labib K; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Diffley JFX; Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.

المصدر: The Biochemical journal [Biochem J] 2021 Jul 16; Vol. 478 (13), pp. 2465-2479.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical*, Antiviral Agents/*chemistry , Antiviral Agents/*pharmacology , Endoribonucleases/*antagonists & inhibitors , SARS-CoV-2/*enzymology , Small Molecule Libraries/*pharmacology , Viral Nonstructural Proteins/*antagonists & inhibitors, Allosteric Regulation ; Animals ; Chlorocebus aethiops ; Endoribonucleases/isolation & purification ; Endoribonucleases/metabolism ; Enzyme Assays ; Fluorescence ; High-Throughput Screening Assays ; In Vitro Techniques ; Kinetics ; Naphthoquinones/pharmacology ; Reproducibility of Results ; SARS-CoV-2/drug effects ; SARS-CoV-2/growth & development ; Small Molecule Libraries/chemistry ; Solutions ; Vero Cells ; Viral Nonstructural Proteins/isolation & purification ; Viral Nonstructural Proteins/metabolism

المؤلفون: Canal B; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., McClure AW; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Curran JF; Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Wu M; High Throughput Screening, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Ulferts R; Cell Biology of Infection Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Weissmann F; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Zeng J; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Bertolin AP; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Milligan JC; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Basu S; Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Drury LS; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Deegan TD; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Fujisawa R; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Roberts EL; Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Basier C; Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Labib K; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Beale R; Cell Biology of Infection Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Howell M; High Throughput Screening, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K., Diffley JFX; Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.

المصدر: The Biochemical journal [Biochem J] 2021 Jul 16; Vol. 478 (13), pp. 2445-2464.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical*, Antiviral Agents/*chemistry , Antiviral Agents/*pharmacology , Exoribonucleases/*antagonists & inhibitors , SARS-CoV-2/*enzymology , Small Molecule Libraries/*pharmacology , Viral Nonstructural Proteins/*antagonists & inhibitors , Viral Regulatory and Accessory Proteins/*antagonists & inhibitors, Animals ; Aurintricarboxylic Acid/pharmacology ; Chlorocebus aethiops ; Enzyme Assays ; Exoribonucleases/metabolism ; Fluorescence ; High-Throughput Screening Assays ; Patulin/pharmacology ; Reproducibility of Results ; SARS-CoV-2/drug effects ; Small Molecule Libraries/chemistry ; Vero Cells ; Viral Nonstructural Proteins/metabolism ; Viral Regulatory and Accessory Proteins/metabolism

المؤلفون: Deegan TD; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Mukherjee PP; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Fujisawa R; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Polo Rivera C; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Labib K; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom.

المصدر: ELife [Elife] 2020 Aug 17; Vol. 9. Date of Electronic Publication: 2020 Aug 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: DNA*/chemistry , DNA*/metabolism , DNA Helicases*/chemistry , DNA Helicases*/metabolism , DNA Replication* , Ubiquitin*/chemistry , Ubiquitin*/metabolism, Escherichia coli ; Humans ; Nucleic Acid Conformation ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Valosin Containing Protein/chemistry ; Valosin Containing Protein/metabolism

المؤلفون: Deegan TD; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK. Electronic address: tdeegan@dundee.ac.uk., Baxter J; Genome Damage and Stability Centre, Department of Life Sciences, University of Sussex, Brighton BN1 9RQ, UK., Ortiz Bazán MÁ; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Yeeles JTP; The MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK., Labib KPM; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK. Electronic address: kpmlabib@dundee.ac.uk.

المصدر: Molecular cell [Mol Cell] 2019 Apr 18; Vol. 74 (2), pp. 231-244.e9. Date of Electronic Publication: 2019 Mar 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: DNA Helicases/*genetics , DNA Replication/*genetics , Saccharomyces cerevisiae/*genetics , Saccharomyces cerevisiae Proteins/*genetics, DNA Topoisomerases/genetics ; Escherichia coli/genetics ; Eukaryota/genetics ; Genomic Instability ; Plasmids/genetics