المؤلفون: Deepankar Gahloth, Graham Heaven, Thomas A. Jowitt, A. Paul Mould, Jordi Bella, Clair Baldock, Philip Woodman, Lydia Tabernero

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/fb9b761d30ea4a3cbb093b0b72f678dd

المؤلفون: James L. Galman, Deepankar Gahloth, Fabio Parmeggiani, Iustina Slabu, David Leys, Nicholas J. Turner

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 6 (2018)

مصطلحات موضوعية: biocatalysis, transaminase, green chemistry, benzylamines, protein structure, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2018.00205/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/181698b9af354475b2cc0b36ac9adada

المؤلفون: Deepankar Gahloth, Karl Fisher, Karl A.P. Payne, Matthew Cliff, Colin Levy, David Leys

المصدر: Gahloth, D, Fisher, K, Payne, K A P, Cliff, M, Levy, C & Leys, D 2022, ' Structural and biochemical characterisation of the prenylated flavin mononucleotide-dependent indole-3-carboxylic acid decarboxylase ', Journal of Biological Chemistry, pp. 101771 . https://doi.org/10.1016/j.jbc.2022.101771

مصطلحات موضوعية: Models, Molecular, Structure-Activity Relationship, Carboxy-Lyases, Flavin Mononucleotide, Manchester Institute of Biotechnology, Cell Biology, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Molecular Biology, Biochemistry, Protein Structure, Tertiary, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c34cebc3155e2a1c0847b69ed09453d
https://www.research.manchester.ac.uk/portal/en/publications/structural-and-biochemical-characterisation-of-the-prenylated-flavin-mononucleotidedependent-indole3carboxylic-acid-decarboxylase(1a645aa3-def4-4286-9fcc-5bca1aa0a7f5).html

المؤلفون: Godwin A, Aleku, Annica, Saaret, Ruth T, Bradshaw-Allen, Sasha R, Derrington, Gabriel R, Titchiner, Irina, Gostimskaya, Deepankar, Gahloth, David A, Parker, Sam, Hay, David, Leys

المصدر: Nature chemical biology. 16(11)

مصطلحات موضوعية: Models, Molecular, Genomic Library, Molecular Structure, Carboxy-Lyases, Carboxylic Acids, Drug Evaluation, Preclinical, Carbon Dioxide, Naphthalenes, Decarboxylation, Hydrocarbons, Aromatic, Enzyme Activation, Structure-Activity Relationship, Biodegradation, Environmental, Mutation, Biocatalysis, Amino Acid Sequence, Oxidoreductases, Styrene, Benzofurans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::79f836bfc8ca83acdbca69e2a4ae567d
https://pubmed.ncbi.nlm.nih.gov/32719558

المؤلفون: Nicholas J. Weise, Fabio Parmeggiani, Deepankar Gahloth, Mark S. Dunstan, Matthew P. Thompson, Nicholas J. Turner, Syed T. Ahmed, David Leys, James L. Galman

المصدر: Advanced Synthesis & Catalysis. 358:3298-3306

مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Enantioselective synthesis, Dehydrogenase, General Chemistry, D-amino acid dehydrogenase, 010402 general chemistry, 01 natural sciences, Reductive amination, 0104 chemical sciences, Enzyme catalysis, Amino acid, Enantiopure drug, Biocatalysis, Organic chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::26bb3c8220c78cc7c17cdeb5d4cce6a8
https://doi.org/10.1002/adsc.201600682

المؤلفون: Deepankar Gahloth, Godwin A. Aleku, David Leys

المصدر: Journal of biotechnology. 307

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Models, Molecular, Carboxylic acid, Reduction Activity, Carboxylic Acids, Bioengineering, Sequence (biology), 01 natural sciences, Applied Microbiology and Biotechnology, Aldehyde, 03 medical and health sciences, Protein Domains, 010608 biotechnology, Amino Acid Sequence, Phylogeny, chemistry.chemical_classification, Aldehydes, Carboxylic acid reductase, General Medicine, Combinatorial chemistry, 030104 developmental biology, Enzyme, chemistry, Biocatalysis, Genetic Engineering, Oxidoreductases, Oxidation-Reduction, Sequence Alignment, NADP, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0387c10b41139b78d4467707611fa1
https://pubmed.ncbi.nlm.nih.gov/31689469

المؤلفون: Stephen A, Marshall, Karl A P, Payne, Karl, Fisher, Deepankar, Gahloth, Samuel S, Bailey, Arune, Balaikaite, Annica, Saaret, Irina, Gostimskaya, Godwin, Aleku, Huanming, Huang, Stephen E J, Rigby, David, Procter, David, Leys

المصدر: Methods in enzymology. 620

مصطلحات موضوعية: Prenylation, Carboxy-Lyases, Flavin Mononucleotide, Escherichia coli Proteins, Electron Spin Resonance Spectroscopy, Escherichia coli, Decarboxylation, Oxidation-Reduction, Recombinant Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::078794f67c40e7afa73e102f1241ef1f
https://pubmed.ncbi.nlm.nih.gov/31072499

المؤلفون: Huan-Ming Huang, David J. Procter, Godwin A. Aleku, Arune Balaikaite, Annica Saaret, Stephen E. J. Rigby, Irina Gostimskaya, Karl A. P. Payne, David Leys, Karl Fisher, Samuel S. Bailey, Stephen A. Marshall, Deepankar Gahloth

مصطلحات موضوعية: chemistry.chemical_classification, Enzyme, Biochemistry, biology, Decarboxylation, Chemistry, Prenyltransferase, biology.protein, Heterologous, Phosphorylation, Flavin group, Oxidative phosphorylation, Cofactor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::228a1fb4edd16998ea10c817d65ecc15
https://doi.org/10.1016/bs.mie.2019.03.022

المؤلفون: Nicholas J. Turner, Mark S. Dunstan, A. Hill, Daniela Quaglia, David Leys, Deepankar Gahloth, Evaldas Klumbys, Nigel S. Scrutton, Michael P. Lockhart-Cairns, Sasha R. Derrington

المصدر: Gahloth, D, Dunstan, M S, Quaglia, D, Klumbys, E, Lockhart-Cairns, M P, Hill, A, Derrington, S R, Scrutton, N S, Turner, N J & Leys, D 2017, ' Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis ', Nature chemical biology, vol. 13, pp. 975-981 . https://doi.org/10.1038/nchembio.2434
Nature chemical biology

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Models, Molecular, Molecular Structure, Stereochemistry, Phosphopantetheine binding, Cell Biology, Reductase, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Aldehyde, Article, Substrate Specificity, 03 medical and health sciences, 030104 developmental biology, Enzyme, chemistry, Docking (molecular), Nonribosomal peptide, Oxidoreductase, Catalytic Domain, Manchester Institute of Biotechnology, Journal Article, Oxidoreductases, Molecular Biology, Adenylylation

وصف الملف: application/pdf; PDF

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391421accf42fd9e5ffac4e4205efe85
https://pure.manchester.ac.uk/ws/files/59204978/18692_3_merged_1496951682.pdf

المؤلفون: Deepankar, Gahloth, Colin, Levy, Graham, Heaven, Flavia, Stefani, Lydia, Wunderley, Paul, Mould, Matthew J, Cliff, Jordi, Bella, Alistair J, Fielding, Philip, Woodman, Lydia, Tabernero

المصدر: Structure(London, England:1993)

مصطلحات موضوعية: Models, Molecular, Binding Sites, Endosomal Sorting Complexes Required for Transport, endosomal ESCRTs regulation, ubiquitin-dependent trafficking, macromolecular substances, Crystallography, X-Ray, Protein Tyrosine Phosphatases, Non-Receptor, Protein Structure, Secondary, Article, mitogenic signaling downregulation, coiled-coil structure, Humans, tumor suppressor phosphatase, Carrier Proteins, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::69aa7d4d40734e66b5a7a8b63a17b2fb
https://pubmed.ncbi.nlm.nih.gov/27839950