المؤلفون: Sonon P; Immunology Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil., Brito Ferreira ML; Hospital da Restauração Governador Paulo Guerra, Recife, Pernambuco, Brazil., Santos Almeida R; Immunology Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil., Saloum Deghaide NH; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Sao Paulo, Brazil., Henrique Willcox G; Laboratório HLA Diagnóstico, Recife, Pernambuco, Brazil., Guimarães EL; Laboratório HLA Diagnóstico, Recife, Pernambuco, Brazil., da Purificação Júnior AF; Virology Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil., Cordeiro MT; Virology Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil., Antunes de Brito CA; Internal Medicine Department, Federal University of Pernambuco, Recife, Pernambuco, Brazil., de Albuquerque MFM; Public Health Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil., Lins RD; Virology Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil., Donadi EA; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Sao Paulo, Brazil., Lucena-Silva N; Immunology Department, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.

المصدر: The Journal of infectious diseases [J Infect Dis] 2021 Aug 02; Vol. 224 (3), pp. 517-525.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Arboviruses*/genetics, Alleles ; Gene Frequency ; Genetic Predisposition to Disease ; HLA-DQ alpha-Chains ; HLA-DQ beta-Chains/genetics ; HLA-DRB1 Chains/genetics ; Haplotypes ; Humans ; Syndrome ; Zika Virus ; Zika Virus Infection

المؤلفون: Ferreira SD; Division of Gastroenterology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil. Electronic address: sandrocferreira@terra.com.br., Chachá SG; Division of Gastroenterology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil; Department of Medicine, University Federal of São Carlos (UFSCAR), Brazil., Souza FF; Division of Gastroenterology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Teixeira AC; Division of Gastroenterology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Santana RC; Division of Infectious Diseases, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Deghaide NH; Division of Clinical Immunology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Rodrigues S; Division of Gastroenterology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Marano LA; Department of Genetics, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Mendes-Junior CT; Departamento de Química - Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP - USP), Brazil., Ramalho LN; Department of Pathology, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Zucoloto S; Department of Pathology, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Donadi EA; Division of Clinical Immunology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil., Martinelli AL; Division of Gastroenterology, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Brazil.

المصدر: Human immunology [Hum Immunol] 2017 Feb; Vol. 78 (2), pp. 166-171. Date of Electronic Publication: 2016 Dec 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Country of Publication: United States NLM ID: 8010936 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1166 (Electronic) Linking ISSN: 01988859 NLM ISO Abbreviation: Hum Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, Viral/*metabolism , HLA-G Antigens/*genetics , Hepatitis B virus/*physiology , Hepatitis B, Chronic/*genetics , INDEL Mutation/*genetics, Adolescent ; Adult ; Aged ; Carrier State ; Child ; Female ; Follow-Up Studies ; Gene Frequency ; Genotype ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Viremia/genetics ; Young Adult

المؤلفون: Brochado MJ; Division of Dermatology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Nascimento DF; Post-Graduate Clinical Medical Area, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Campos W; Laboratory of Biochemistry and Phytopathology, Biological Institute, São Paulo, São Paulo, Brazil., Deghaide NH; Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Donadi EA; Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address: eadonadi@fmrp.usp.br., Roselino AM; Division of Dermatology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address: amfrosel@fmrp.usp.br.

المصدر: Journal of autoimmunity [J Autoimmun] 2016 Aug; Vol. 72, pp. 19-24. Date of Electronic Publication: 2016 May 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 8812164 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9157 (Electronic) Linking ISSN: 08968411 NLM ISO Abbreviation: J Autoimmun Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease/*genetics , HLA Antigens/*genetics , Pemphigus/*genetics, Adult ; Aged ; Alleles ; Brazil/epidemiology ; Female ; Gene Frequency ; Genotype ; HLA Antigens/classification ; HLA-A Antigens/genetics ; HLA-B Antigens/genetics ; HLA-C Antigens/genetics ; HLA-DQ alpha-Chains/genetics ; HLA-DQ beta-Chains/genetics ; HLA-DRB1 Chains/genetics ; Haplotypes ; Humans ; Male ; Middle Aged ; Pemphigus/epidemiology ; Prevalence ; Young Adult

المؤلفون: Salathiel AM; Laboratory of Dermatology, University Hospital, Division of Dermatology, Department of Medical Clinics, Ribeirao Preto Medical School - University of Sao Paulo, Brazil., Brochado MJ; Laboratory of Dermatology, University Hospital, Division of Dermatology, Department of Medical Clinics, Ribeirao Preto Medical School - University of Sao Paulo, Brazil., Kim O; Laboratory of Dermatology, University Hospital, Division of Dermatology, Department of Medical Clinics, Ribeirao Preto Medical School - University of Sao Paulo, Brazil., Deghaide NH; Laboratory of Immunogenetics of Blood Donor Center, Division of Immunology, Department of Medical Clinics, Ribeirao Preto Medical School - University of Sao Paulo, Brazil., Donadi EA; Laboratory of Immunogenetics of Blood Donor Center, Division of Immunology, Department of Medical Clinics, Ribeirao Preto Medical School - University of Sao Paulo, Brazil., Roselino AM; Laboratory of Dermatology, University Hospital, Division of Dermatology, Department of Medical Clinics, Ribeirao Preto Medical School - University of Sao Paulo, Brazil. Electronic address: amfrosel@fmrp.usp.br.

المصدر: Human immunology [Hum Immunol] 2016 Jul; Vol. 77 (7), pp. 600-4. Date of Electronic Publication: 2016 May 10.

نوع المنشور: Case Reports; Journal Article; Review; Twin Study

بيانات الدورية: Publisher: Elsevier/North-Holland Country of Publication: United States NLM ID: 8010936 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1166 (Electronic) Linking ISSN: 01988859 NLM ISO Abbreviation: Hum Immunol Subsets: MEDLINE

مواضيع طبية MeSH: HLA-DQ alpha-Chains/*genetics , HLA-DQ beta-Chains/*genetics , HLA-DRB1 Chains/*genetics , Pemphigus/*genetics, Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Autoantibodies/blood ; Brazil ; Desmoglein 1/immunology ; Desmoglein 3/immunology ; Drug Resistance ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Pedigree ; Pemphigus/diagnosis ; Pemphigus/drug therapy ; Polymorphism, Genetic ; Twins, Monozygotic/genetics

المؤلفون: Franco Brochado MJ; Division of Dermatology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Nascimento DF; Division of Dermatology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Saloum Deghaide NH; Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Donadi EA; Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Roselino AM; Division of Dermatology, Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

المصدر: Data in brief [Data Brief] 2016 Jun 03; Vol. 8, pp. 364-74. Date of Electronic Publication: 2016 Jun 03 (Print Publication: 2016).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101654995 Publication Model: eCollection Cited Medium: Print ISSN: 2352-3409 (Print) Linking ISSN: 23523409 NLM ISO Abbreviation: Data Brief Subsets: PubMed not MEDLINE

المؤلفون: de Albuquerque RS; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Departament of Genetics, Ribeirão Preto, SP, Brazil; Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), San Raffaele Scientific Institute, Milan, Italy., Mendes-Junior CT; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: ctmendes@ffclrp.usp.br., Lucena-Silva N; Aggeu Magalhães Research Center, Department of Immunology, Oswaldo Cruz Fundation (Fiocruz), Recife, PE, Brazil., da Silva CL; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil., Rassi DM; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Department of Medicine, Ribeirão Preto, SP, Brazil., Veiga-Castelli LC; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Department of Medicine, Ribeirão Preto, SP, Brazil., Foss-Freitas MC; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Department of Medicine, Ribeirão Preto, SP, Brazil., Foss MC; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Department of Medicine, Ribeirão Preto, SP, Brazil., Deghaide NH; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Department of Medicine, Ribeirão Preto, SP, Brazil., Moreau P; UMR Commissariat à l'Energie Atomique et aux Energies Alternatives/Université Paris Diderot-Paris 7, Sorbonne Paris-Cité/iMETI/Service de Recherches en Hémato-Immunologie, Hôpital Saint-Louis, IUH, Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75475 Paris cedex 10, France., Gregori S; Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), San Raffaele Scientific Institute, Milan, Italy., Castelli EC; Departamento de Patologia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brazil., Donadi EA; Faculty of Medicine of Ribeirão Preto, University of São Paulo, Department of Medicine, Ribeirão Preto, SP, Brazil.

المصدر: Human immunology [Hum Immunol] 2016 Apr; Vol. 77 (4), pp. 358-64. Date of Electronic Publication: 2016 Feb 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier/North-Holland Country of Publication: United States NLM ID: 8010936 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1166 (Electronic) Linking ISSN: 01988859 NLM ISO Abbreviation: Hum Immunol Subsets: MEDLINE

مواضيع طبية MeSH: 3' Untranslated Regions* , Genetic Variation*, Diabetes Mellitus, Type 1/*genetics , HLA-G Antigens/*genetics, Adolescent ; Adult ; Alleles ; Case-Control Studies ; Child ; Female ; Gene Frequency ; Genotype ; Humans ; Linkage Disequilibrium ; Male ; Middle Aged ; Odds Ratio ; Polymorphism, Single Nucleotide ; Young Adult

المؤلفون: Rodrigues Mde L; Department of Ophthalmology, Otorhinolaringology and Head and Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil., Deghaide NH; Department of Medical Clinical, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil., Figueiredo JF; Department of Medical Clinical, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil., de Menezes MB; Department of Ophthalmology, Otorhinolaringology and Head and Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil., Demarco AL; Department of Ophthalmology, Otorhinolaringology and Head and Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil., Donadi E; Department of Medical Clinical, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil., Fernandes AP; Department of General and Specialized Nursing, Escola de Enfermagem de Ribeirão Preto, Universidade de São Paulo (EERP-USP), Ribeirão Preto, SP, Brazil. Electronic address: anapaula@eerp.usp.br.

المصدر: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2016 Mar-Apr; Vol. 20 (2), pp. 115-8. Date of Electronic Publication: 2016 Jan 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Editora Country of Publication: Brazil NLM ID: 9812937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4391 (Electronic) Linking ISSN: 14138670 NLM ISO Abbreviation: Braz J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Alleles*, Acquired Immunodeficiency Syndrome/*blood , HLA Antigens/*blood , Infectious Encephalitis/*blood , Toxoplasmosis, Cerebral/*blood, Acquired Immunodeficiency Syndrome/complications ; Acquired Immunodeficiency Syndrome/genetics ; Adult ; Biomarkers/blood ; Disease Progression ; Female ; Humans ; Infectious Encephalitis/genetics ; Infectious Encephalitis/parasitology ; Male ; Middle Aged ; Toxoplasmosis, Cerebral/complications ; Toxoplasmosis, Cerebral/genetics ; Young Adult

المؤلفون: Ferreira Sda C; Gastroenterology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Chachá SG; Gastroenterology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil.; Department of Medicine, Federal University of São Carlos (UFSCAR), Ribeirão Preto, São Paulo, Brazil., Souza FF; Gastroenterology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Teixeira AC; Gastroenterology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Santana Rde C; Infectious Diseases Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Deghaide NH; Clinical Immunology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Rodrigues S; Gastroenterology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Marano LA; Genetics Department, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Mendes-Junior CT; Departamento de Química - Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP - USP), Ribeirão Preto, São Paulo, Brazil., Zucoloto S; Pathology Department, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Donadi EA; Clinical Immunology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil., Martinelli Ade L; Gastroenterology Division, Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil.

المصدر: Journal of medical virology [J Med Virol] 2015 Oct; Vol. 87 (10), pp. 1689-96. Date of Electronic Publication: 2015 May 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Single Nucleotide*, Hepatitis B, Chronic/*genetics , Interferon-gamma/*genetics , Interleukin-18/*genetics , Liver Cirrhosis/*genetics , Tumor Necrosis Factor-alpha/*genetics, Adolescent ; Adult ; Aged ; Alleles ; Brazil ; Female ; Genetic Predisposition to Disease ; Genotype ; Hepatitis B, Chronic/immunology ; Hepatitis B, Chronic/pathology ; Hepatitis B, Chronic/virology ; Humans ; Interferon-gamma/immunology ; Interleukin-18/immunology ; Liver/immunology ; Liver/pathology ; Liver/physiopathology ; Liver/virology ; Liver Cirrhosis/virology ; Male ; Middle Aged ; Tumor Necrosis Factor-alpha/immunology ; Young Adult

المؤلفون: Borges AA; Virology Research Center, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil., Donadi EA, Campos GM, de Figueiredo GG, Saggioro FP, Badra SJ, Deghaide NH, Figueiredo LT

المصدر: Journal of medical virology [J Med Virol] 2014 Nov; Vol. 86 (11), pp. 1962-70. Date of Electronic Publication: 2013 Nov 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Genetic*, Antigens, Human Platelet/*genetics , Cytokines/*genetics , HLA Antigens/*genetics , Hantavirus Pulmonary Syndrome/*genetics, Adolescent ; Adult ; Brazil ; Disease Susceptibility ; Female ; Humans ; Male ; Middle Aged ; Young Adult

المؤلفون: Teixeira AC; Department of Internal Medicine, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto-Universidade de São Paulo, 14048-900 Ribeirão Preto, São Paulo, Brazil. andrezacteixeira@gmail.com, Mendes CT Jr, Marano LA, Deghaide NH, Secaf M, Elias J Jr, Muglia V, Donadi EA, Martinelli AL

المصدر: Human immunology [Hum Immunol] 2013 Aug; Vol. 74 (8), pp. 1024-9. Date of Electronic Publication: 2013 Apr 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Country of Publication: United States NLM ID: 8010936 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1166 (Electronic) Linking ISSN: 01988859 NLM ISO Abbreviation: Hum Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Single Nucleotide*, Carcinoma, Hepatocellular/*genetics , Interferon-gamma/*genetics , Interleukin-18/*genetics , Liver Neoplasms/*genetics , Tumor Necrosis Factor-alpha/*genetics, Adolescent ; Adult ; Aged ; Alleles ; Brazil ; Case-Control Studies ; Cross-Sectional Studies ; Female ; Gene Frequency ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Middle Aged ; Odds Ratio ; Retrospective Studies ; Risk ; Young Adult