نتائج البحث - "Deleobuvir"

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كتاب إلكتروني

Evolution of HCV NS5B Non-nucleoside Inhibitors

المساهمون: Bernstein, Peter R., Series Editor^Aff1, Garner, Amanda L., Series Editor^Aff2, Georg, Gunda I., Series Editor^Aff3, Kobayashi, Toshi, Series Editor^Aff4, Lowe, John A., Series Editor^Aff5, Meanwell, Nicholas A., Series Editor^Aff6, Saxena, Anil Kumar, Series Editor^Aff7, Stilz, Ulrich, Series Editor^Aff8, Supuran, Claudiu T., Series Editor^Aff9, Zhang, Ao, Series Editor^Aff10, Sofia, Michael J., editor^Aff11

المصدر: HCV: The Journey from Discovery to a Cure : Volume I. 31:171-191

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Treatment of Extrahepatic Manifestations of Hepatitis C Virus

المؤلفون: Massimo Colombo, Elisabetta Degasperi, Alessio Aghemo

المصدر: Clinics in Liver Disease. 21:631-643

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f84f720e3f8e1003b78d085e41d837
https://doi.org/10.1016/j.cld.2017.03.015

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Full Text via ClinicalKey

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Evolution of HCV NS5B Non-nucleoside Inhibitors

المؤلفون: William J. Watkins

المصدر: Topics in Medicinal Chemistry ISBN: 9783030282066

مصطلحات موضوعية: Radalbuvir, Dasabuvir, biology, business.industry, Allosteric regulation, Deleobuvir, Virology, chemistry.chemical_compound, chemistry, biology.protein, Medicine, business, Beclabuvir, NS5B, Nucleoside, Polymerase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5848abdf44a8b4a246832b651545ffd7
https://doi.org/10.1007/7355_2018_35

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Open-label phase 2 study of faldaprevir, deleobuvir and ribavirin in Japanese treatment-naive patients with chronic hepatitis C virus genotype 1 infection

المؤلفون: Masao Omata, Hiroshi Yatsuhashi, Hiroyuki Ugai, Nobuyoshi Kodani

المصدر: Hepatology Research. 46:E189-E193

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::26c74d6d958ea057e98a4f6e516cd57e
https://doi.org/10.1111/hepr.12535

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Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies

المؤلفون: Michelle McCabe, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Rucha S. Sane, Donald J. Tweedie, Yongmei Li, Nicholas Johnstone

المصدر: Drug Metabolism and Disposition. 43:1612-1618

مصطلحات موضوعية: Male, medicine.medical_specialty, Metabolite, Pharmaceutical Science, Biology, Rats, Sprague-Dawley, Excretion, Feces, chemistry.chemical_compound, In vivo, Internal medicine, medicine, Animals, Humans, Pharmacology, Cross-Over Studies, Deleobuvir, Area under the curve, Metabolism, Gastrointestinal Microbiome, Rats, Endocrinology, Acrylates, chemistry, Microsomes, Liver, Microsome, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dd087a3900fe5b76bb18ac58ab27d1
https://doi.org/10.1124/dmd.115.064477

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Synthesis of deleobuvir, a potent hepatitis C virus polymerase inhibitor, and its major metabolites labeled with carbon-13 and carbon-14

المؤلفون: Chris H. Senanayake, Carl A. Busacca, Scot Campbell, Bachir Latli, Matt Hrapchak, Maxim Chevliakov, Guisheng Li

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 58:250-260

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4a53a24bb2928cb5b527a9bef4422e79
https://doi.org/10.1002/jlcr.3294

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Interferon-free treatment of chronic hepatitis C with faldaprevir, deleobuvir and ribavirin: SOUND-C3, a Phase 2b study

المؤلفون: Federico J. Mensa, Jerry O. Stern, Vicente Soriano, Maria Buti, Jawahar Taunk, Jean-François Dufour, Richard Vinisko, Parvez S. Mantry, Wulf O. Böcher, John-Paul Gallivan, Robert Buynak, Stefan Zeuzem

المصدر: Liver International. 35:417-421

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c02c53a983569080093b917d954db7b
https://doi.org/10.1111/liv.12693

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Current Status in the Therapy of Liver Diseases

المؤلفون: Philipp Uhl, Gert Fricker, Walter Mier, Uwe Haberkorn

المصدر: International Journal of Molecular Sciences, Vol 15, Iss 5, Pp 7500-7512 (2014)
International Journal of Molecular Sciences

مصطلحات موضوعية: molecular mechanisms, Autoimmune hepatitis, Review, Gastroenterology, lcsh:Chemistry, chemistry.chemical_compound, entry inhibitors, hepatitis, lcsh:QH301-705.5, Spectroscopy, Liver Diseases, Liver Neoplasms, virus diseases, General Medicine, hepatocellular carcinoma, Hepatitis B, Hepatitis D, Computer Science Applications, Liver, Hereditary hemochromatosis, hepatic diseases, Drug Therapy, Combination, Viral hepatitis, medicine.medical_specialty, Carcinoma, Hepatocellular, Hepatitis, Viral, Human, liver cirrhosis, Antineoplastic Agents, Antiviral Agents, Catalysis, Inorganic Chemistry, Internal medicine, medicine, Animals, Humans, Protease Inhibitors, Physical and Theoretical Chemistry, Molecular Biology, Hepatitis, business.industry, Organic Chemistry, Deleobuvir, medicine.disease, digestive system diseases, chemistry, lcsh:Biology (General), lcsh:QD1-999, Faldaprevir, Immunology, Interferons, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ced6ddd875b59b089473e938b2a2350
http://www.mdpi.com/1422-0067/15/5/7500

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Resistance Analyses of HCV NS3/4A Protease and NS5B Polymerase from Clinical Studies of Deleobuvir and Faldaprevir

المؤلفون: Martin Marquis, Christoph Sarrazin, Federico J. Mensa, Alexandra Côté-Martin, Richard Vinisko, David R. Nelson, George Kukolj, Jerry O. Stern, Kristi L. Berger, Joseph Scherer, Nanshi Sha

المصدر: PLoS ONE, Vol 11, Iss 8, p e0160668 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, RNA viruses, Aminoisobutyric Acids, viruses, lcsh:Medicine, Drug resistance, Hepacivirus, Drug research and development, Viral Nonstructural Proteins, medicine.disease_cause, Biochemistry, Polymerases, chemistry.chemical_compound, 0302 clinical medicine, Clinical trials, Amino Acids, lcsh:Science, Pathology and laboratory medicine, education.field_of_study, Multidisciplinary, Alanine, Clinical Trials, Phase I as Topic, Hepatitis C virus, Organic Compounds, Intracellular Signaling Peptides and Proteins, virus diseases, Hepatitis C, Medical microbiology, Phase III clinical investigation, Chemistry, Treatment Outcome, Acrylates, Viruses, Physical Sciences, Amino Acid Analysis, Quinolines, 030211 gastroenterology & hepatology, Pathogens, Oligopeptides, Phase II clinical investigation, Research Article, animal structures, Proline, 030106 microbiology, Population, Biology, Microbiology, Antiviral Agents, 03 medical and health sciences, Clinical Trials, Phase II as Topic, Leucine, Microbial Control, DNA-binding proteins, Drug Resistance, Viral, medicine, Humans, Protease Inhibitors, ddc:610, education, Molecular Biology Techniques, Molecular Biology, Medicine and health sciences, Pharmacology, Molecular Biology Assays and Analysis Techniques, Polymorphism, Genetic, Biology and life sciences, Flaviviruses, Ribavirin, Organic Chemistry, lcsh:R, Deleobuvir, Organisms, Viral pathogens, Chemical Compounds, Proteins, Hepatitis C, Chronic, biochemical phenomena, metabolism, and nutrition, medicine.disease, Virology, Hepatitis viruses, digestive system diseases, Microbial pathogens, Research and analysis methods, Regimen, Thiazoles, chemistry, Amino Acid Substitution, Aliphatic Amino Acids, Clinical Trials, Phase III as Topic, Clinical medicine, Faldaprevir, Mutation, Benzimidazoles, lcsh:Q, Antimicrobial Resistance, Carrier Proteins

وصف الملف: application/octet-stream

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af5b9ac93afd81e36bfc74cf0d553fa
http://europepmc.org/articles/PMC4975400?pdf=render

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HCVerso3: An Open-Label, Phase IIb Study of Faldaprevir and Deleobuvir with Ribavirin in Hepatitis C Virus Genotype-1b-Infected Patients with Cirrhosis and Moderate Hepatic Impairment

المؤلفون: Jing Wu, Michael P. Manns, Xavier Forns, Xiaofei Bai, Javier García-Samaniego, Jose Luis Calleja, Christoph Sarrazin, Jerry O. Stern, Renee Kaste

المساهمون: Su, Chien-Wei, Universitat de Barcelona

المصدر: Dipòsit Digital de la UB
Universidad de Barcelona
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0168544 (2016)

مصطلحات موضوعية: Male, Cirrhosis, Drug research and development, Hepacivirus, Gastroenterology, 0302 clinical medicine, lcsh:Science, Liver Diseases, Malalties del fetge, Prognosis, Acrylates, Vomiting, 030211 gastroenterology & hepatology, Drug Therapy, Combination, Oligopeptides, Diarrhea, medicine.medical_specialty, Proline, Genotype, Nausea, 030106 microbiology, Gastroenterology and Hepatology, Microbiology, Antiviral Agents, 03 medical and health sciences, Signs and Symptoms, Humans, Adverse effect, Liver diseases, Aged, Medicine and health sciences, Pharmacology, Flaviviruses, lcsh:R, Organisms, medicine.disease, Regimen, Thiazoles, chemistry, Clinical medicine, Faldaprevir, Virus de l'hepatitis C, lcsh:Q, Benzimidazoles, Physiological Processes, RNA viruses, 0301 basic medicine, Liver Cirrhosis, Aminoisobutyric Acids, Physiology, lcsh:Medicine, chemistry.chemical_compound, Clinical trials, Pathology and laboratory medicine, Multidisciplinary, Hepatitis C virus, Medical microbiology, Middle Aged, Viral Load, Phase III clinical investigation, Hepatic cirrhosis, Research Design, Viruses, Quinolines, RNA, Viral, Female, Pathogens, medicine.symptom, Research Article, Adult, Cirrosi hepàtica, Adolescent, Clinical Research Design, Research and Analysis Methods, Young Adult, Diagnostic Medicine, Leucine, Internal medicine, Ribavirin, medicine, Pharmacokinetics, ddc:610, Biology and life sciences, business.industry, Viral pathogens, Deleobuvir, Hepatitis C, Chronic, Hepatitis viruses, Microbial pathogens, Surgery, Adverse Events, business, Follow-Up Studies, Assaigs clínics

وصف الملف: application/pdf; application/octet-stream

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865b5224fbc0f2b8b80b0cf1453ac510
http://hdl.handle.net/2445/130887

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