-
1
المؤلفون: Helene Jary, Pierre Deprez, Denis Guédin, Taoues Temal, Marielle Auberval, Sarah E. Lively, Jean-Paul Vevert
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:2455-2459
مصطلحات موضوعية: Stereochemistry, Calcimimetic, Organic Chemistry, Clinical Biochemistry, Allosteric regulation, Pharmaceutical Science, Pharmacology, Biochemistry, chemistry.chemical_compound, chemistry, Benzothiazole, Oral administration, In vivo, Drug Discovery, Urea, Molecular Medicine, Calcium, Luciferase, Benzothiazoles, Calcium-sensing receptor, Receptors, Calcium-Sensing, Molecular Biology
-
2
المؤلفون: Catherine Robin-Jagerschmidt, Helene Jary, Ellen van der Aar, Nicolas Triballeau, Luke Jonathan Alvey, Francois Nique, Denis Guédin, Kris Van Beeck, Dominque Minet, Florence Namour, Jean H.M. Feyen, Pierre Deprez, Hugo Klaassen, Jean-Michel Lefrancois, Roland Blanque, Christophe Peixoto, Murielle Manioc, Séverine Hebbe, Stephen Robert Fletcher, Christopher Gaëtan Housseman
المصدر: Journal of Medicinal Chemistry. 55:8236-8247
مصطلحات موضوعية: Male, Models, Molecular, Transcriptional Activation, Stereochemistry, Molecular Conformation, Biological Availability, Hydantoin, Pharmacology, Partial agonist, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Anabolic Agents, In vivo, Drug Discovery, Androgen Receptor Antagonists, Animals, Humans, Hydroxymethyl, Muscle, Skeletal, Trifluoromethyl, Hydantoins, Prostate, Stereoisomerism, Organ Size, Rats, Bioavailability, Drug Partial Agonism, Androgen receptor, chemistry, Selective androgen receptor modulator, Receptors, Androgen, Androgens, Molecular Medicine, Orchiectomy, HeLa Cells
-
3
المؤلفون: Denis Guédin, Marcel Hibert, Philippe Bernard
المصدر: Journal of Medicinal Chemistry. 44:27-35
مصطلحات موضوعية: Models, Molecular, Molecular model, Chemistry, Molecular Sequence Data, GABAB receptor, Ligands, Homology (biology), Receptors, GABA-B, Biochemistry, Drug Discovery, Extracellular, Biophysics, Molecular Medicine, Amino Acid Sequence, Isoleucine, Binding site, Leucine, Receptor
-
4
المؤلفون: Sarah E. Lively, Jean-Paul Vevert, Helene Jary, Denis Guédin, Pierre Deprez, Marielle Auberval, Taoues Temal
المصدر: Bioorganicmedicinal chemistry letters. 23(8)
مصطلحات موضوعية: Fendiline, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Allosteric regulation, Substituent, Pharmaceutical Science, medicine.disease, Biochemistry, In vitro, chemistry.chemical_compound, Structure-Activity Relationship, chemistry, In vivo, Biomimetic Materials, Drug Discovery, Urea, medicine, Molecular Medicine, Secondary hyperparathyroidism, Calcium, Calcium-sensing receptor, Molecular Biology, Receptors, Calcium-Sensing
-
5
المؤلفون: Francois Nique, Denis Guédin, Nicolas Triballeau, Eric Duval, Jean-Michel Lemoullec, Denis Annoot, Catherine Robin-Jagerschmidt, Maxime Thauvin, Jean-Michel Lefrancois, Thierry Prangé, Laurence Michoux, Philippe Clément-Lacroix, Damien Fleury, Pierre Deprez, Patrick Mollat, Séverine Hebbe, Dominique Minet, Christophe Peixoto
المصدر: Journal of medicinal chemistry. 55(19)
مصطلحات موضوعية: Male, Models, Molecular, Transcriptional Activation, medicine.medical_specialty, Antiandrogens, Hydantoin, Peptide, Pharmacology, Crystallography, X-Ray, Binding, Competitive, Bone and Bones, Transactivation, chemistry.chemical_compound, Structure-Activity Relationship, Anabolic Agents, Internal medicine, Drug Discovery, medicine, Androgen Receptor Antagonists, Potency, Animals, Humans, Muscle, Skeletal, chemistry.chemical_classification, Hydantoins, Prostate, Stereoisomerism, In vitro, Rats, Androgen receptor, Drug Partial Agonism, Endocrinology, Selective androgen receptor modulator, chemistry, Receptors, Androgen, Androgens, Molecular Medicine, Orchiectomy, HeLa Cells
-
6
المؤلفون: Tina Garyantes, Denis Guédin, Pascal Collette, Paul Fogel, Alain Dupront
المصدر: Journal of biomolecular screening. 7(3)
مصطلحات موضوعية: 0301 basic medicine, Computer science, 01 natural sciences, Biochemistry, 0104 chemical sciences, Analytical Chemistry, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, 030104 developmental biology, Binary classification, Positive predicative value, Data Interpretation, Statistical, False positive paradox, Molecular Medicine, Cutoff, Per-comparison error rate, Biological Assay, False Positive Reactions, Deconvolution, Algorithm, True positive rate, Biotechnology, Primary screening
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4b4b8eea411d8c8fe7e34bdf30c89a
https://pubmed.ncbi.nlm.nih.gov/12097182 -
7
المؤلفون: Marcel Hibert, Philippe Bernard, Denis Guédin
المصدر: European Neuropsychopharmacology. 10:212-213
مصطلحات موضوعية: Pharmacology, Molecular model, biology, Chemistry, Allosteric regulation, GABAB receptor, Psychiatry and Mental health, Neurology, Allosteric enzyme, biology.protein, Biophysics, Pharmacology (medical), Neurology (clinical), Binding site, Biological Psychiatry