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1
المؤلفون: Jeremy L. Jenkins, Katrin Volkmann, Shelly Meeusen, Prisca Liberali, Karyn Colman, Ludivine Challet Meylan, Michael B. Stadler, Ilya Lukonin, Janine E. Baaten, Denise Serra, Rui Zhao, Francisca Maurer
المصدر: Nature
مصطلحات موضوعية: Male, 0301 basic medicine, Transcription, Genetic, Receptors, Retinoic Acid, Retinoic acid, Tretinoin, Biology, Retinoid X receptor, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Organoid, Animals, Homeostasis, Regeneration, Intestinal Mucosa, Vitamin A, Multidisciplinary, Sequence Analysis, RNA, Cell Differentiation, Phenotype, Intestinal epithelium, Cell biology, Intestines, Mice, Inbred C57BL, Organoids, Enterocytes, 030104 developmental biology, Nuclear receptor, chemistry, 030220 oncology & carcinogenesis, Enterocyte differentiation, Stem cell, Signal Transduction
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2دورية أكاديمية
المؤلفون: Ilya Lukonin, Denise Serra, Ludivine Challet Meylan, Katrin Volkmann, Janine Baaten, Rui Zhao, Shelly Meeusen, Karyn Colman, Francisca Maurer, Michael B. Stadler, Jeremy Jenkins, Prisca Lib
المصدر: Nature, Nature. 586(7828):275-280
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3دورية أكاديمية
المؤلفون: Denise Serra, Urs Mayr, Andrea Boni, Ilya Lukonin, Markus Rempfler, Ludivine Challet Meylan, Michael B. Stadler, Petr Strnad, Panagiotis Papasaikas, Dario Vischi, Annick Waldt, Guglielmo Ro
المصدر: Nature, Nature. 569(7754):66-72
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المؤلفون: Urs Mayr, Prisca Liberali, Denise Serra
المصدر: Development
مصطلحات موضوعية: Collective behavior, Proteome, Gene regulatory network, Design elements and principles, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Live cell imaging, RNA, Small Cytoplasmic, Animals, Homeostasis, Humans, Regeneration, Cell Lineage, Gene Regulatory Networks, RNA, Messenger, Molecular Biology, Temporal information, In Situ Hybridization, Fluorescence, Organism, 030304 developmental biology, 0303 health sciences, Regeneration (biology), Gene Expression Regulation, Developmental, Single-Cell Analysis, Neuroscience, 030217 neurology & neurosurgery, Developmental Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52968d4b25b5a4f5f0393fd8a54ff46f
https://doi.org/10.1242/dev.176727 -
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المؤلفون: Denise Serra, Urs Mayr, Andrea Boni, Ilya Lukonin, Markus Rempfler, Ludivine Challet Meylan, Michael B. Stadler, Petr Strnad, Panagiotis Papasaikas, Dario Vischi, Annick Waldt, Guglielmo Roma, Prisca Liberali
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e876d96e1485e608b80ad87d88ebbf84
https://doi.org/10.21203/rs.2.9220/v1 -
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المؤلفون: Urs Mayr, Guglielmo Roma, Michael B. Stadler, Denise Serra, Markus Rempfler, Dario Vischi, Ludivine Challet Meylan, Ilya Lukonin, Petr Strnad, Panagiotis Papasaikas, Andrea Boni, Annick Waldt, Prisca Liberali
المصدر: Nature
مصطلحات موضوعية: Paneth Cells, Cell, Cell Cycle Proteins, Article, Receptors, G-Protein-Coupled, 03 medical and health sciences, Mice, 0302 clinical medicine, Single-cell analysis, Organoid, medicine, Animals, Cell Cycle Protein, 030304 developmental biology, Adaptor Proteins, Signal Transducing, 0303 health sciences, Multidisciplinary, Chemistry, Regeneration (biology), Calcium-Binding Proteins, YAP-Signaling Proteins, Phosphoproteins, Cell biology, Intestines, Organoids, Multicellular organism, medicine.anatomical_structure, Paneth cell, Intercellular Signaling Peptides and Proteins, Stem cell, Single-Cell Analysis, 030217 neurology & neurosurgery
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المصدر: Cornea
مصطلحات موضوعية: Adult, Male, inflammatory cytokine, medicine.medical_specialty, Adolescent, Interleukin-1beta, Dry Eye Syndromes, Antibodies, Monoclonal, Humanized, Placebo, canakinumab, law.invention, dry eye, Young Adult, Double-Blind Method, Randomized controlled trial, law, Internal medicine, IL-17A, Clinical endpoint, Humans, Medicine, Ocular Surface Disease Index, Adverse effect, Aged, Aged, 80 and over, business.industry, secukinumab, Interleukin-17, Antibodies, Monoclonal, clinical trial, Clinical Science, Middle Aged, eye diseases, Surgery, Ophthalmology, Canakinumab, IL-1β, inflammation, Tears, Injections, Intravenous, Female, Secukinumab, sense organs, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93abfbb12476664ca3a8c8a20581c04e
https://doi.org/10.1097/ico.0000000000000627 -
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المؤلفون: Evan Beckman, Jang-Ho Cha, Oleksandr Sverdlov, Denise Serra, Mark Deurinck, Jelena Curcic, Tricia A. Thornton-Wells, Jens Praestgaard, Ana Graf, Tilo Hache, Ricardo E. Dolmetsch, Ieuan Clay, Kristin Hannesdottir, Gabriel Vargas
المصدر: Alzheimer's & Dementia. 14
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, business
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9
المؤلفون: Steen H. Hansen, Francesco Niola, Morten Frödin, Lars H. Engelholm, Jens Vilstrup Johansen, Anjum Riaz, Eric Santoni-Rugiu, Denise Serra, Frederik Dagnæs-Hansen
المصدر: Engelholm, L H, Riaz, A, Serra, D, Dagnæs-Hansen, F, Johansen, J V, Santoni-Rugiu, E, Hansen, S H, Niola, F & Frödin, M 2017, ' CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma ', Gastroenterology, pp. 1662-1673 . https://doi.org/10.1053/j.gastro.2017.09.008
Engelholm, L H, Riaz, A, Serra, D, Dagnæs-Hansen, F, Johansen, J V, Santoni-Rugiu, E, Hansen, S H, Niola, F & Frödin, M 2017, ' CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma ', Gastroenterology, vol. 153, no. 6, pp. 1662-1673.e10 . https://doi.org/10.1053/j.gastro.2017.09.008مصطلحات موضوعية: Genomic Engineering, Liver Cancer, 0301 basic medicine, Carcinoma, Hepatocellular, Time Factors, Liver tumor, CRISPR-Associated Proteins, Biology, Article, Fusion gene, Mice, 03 medical and health sciences, Exon, Liver disease, 0302 clinical medicine, Biomarkers, Tumor, medicine, Journal Article, Protein Kinase A, Animals, PKA, Clustered Regularly Interspaced Short Palindromic Repeats, Genetic Predisposition to Disease, Gene, Gene Editing, Cyclic AMP-Dependent Protein Kinase Catalytic Subunits, Mouse Model, Hepatology, Liver Neoplasms, Gastroenterology, HSP40 Heat-Shock Proteins, medicine.disease, Molecular biology, PRKACA, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, Phenotype, 030104 developmental biology, Fibrolamellar hepatocellular carcinoma, 030220 oncology & carcinogenesis, Disease Progression, Cancer research, Female, CRISPR-Cas Systems, Gene Fusion, Liver cancer
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092adf00daca6ce48473b5a0f1635494
https://pure.au.dk/portal/da/publications/crisprcas9-engineering-of-adult-mouse-liver-demonstrates-that-the-dnajb1prkaca-gene-fusion-is-sufficient-to-induce-tumors-resembling-fibrolamellar-hepatocellular-carcinoma(e3d0daa3-7574-4806-99a3-bf31482b2ccf).html -
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المؤلفون: Venkateswar Jarugula, Monica Ligueros-Saylan, Christine Reynolds, Serge Winter, Surya Ayalasomayajula, Gangadhar Sunkara, Xuemin Jiang, Yiming Zhang, Denise Serra
المصدر: Clinical Pharmacology in Drug Development. 3:487-492
مصطلحات موضوعية: business.industry, Fixed-dose combination, Cmax, Healthy subjects, Pharmaceutical Science, Pharmacology, Bioavailability, Hydrochlorothiazide, Pharmacokinetics, Valsartan, Medicine, Pharmacology (medical), Amlodipine, business, medicine.drug
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