المؤلفون: Emilie Anduran, Ashok Aspatwar, Nanda-Kumar Parvathaneni, Dennis Suylen, Silvia Bua, Alessio Nocentini, Seppo Parkkila, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Jean-Yves Winum

المصدر: Molecules, Vol 25, Iss 10, p 2347 (2020)

مصطلحات موضوعية: hypoxia-activated prodrug, carbonic anhydrase, inhibitors, sulfonamides, hypoxic tumour, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/10/2347; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/a8b3665cc17c46e1877cc22773b10067

المؤلفون: Ketan A. Ganar, Polina Turbina, Manali Nandy, Chang Chen, Dennis Suylen, Stan van der Beelen, Emily Louise Pascoe, Constantianus J.M. Koenraadt, Ingrid Dijkgraaf, Siddharth Deshpande

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5d688455db94180eb50b197a21537757
https://doi.org/10.1101/2023.03.27.534361

المؤلفون: Shahzad Hafeez, Huey Wen Ooi, Dennis Suylen, Hans Duimel, Tilman M. Hackeng, Clemens van Blitterswijk, Matthew B. Baker

المساهمون: RS: MERLN - Complex Tissue Regeneration (CTR), CTR, RS: M4I - Nanoscopy, Institute of Nanoscopy (IoN), RS: Carim - B01 Blood proteins & engineering, Biochemie

المصدر: Journal of the American Chemical Society, 144(9), 4057-4070. American Chemical Society

مصطلحات موضوعية: AMINOLYSIS, PATHWAYS, Benzene, Esters, Hydrogels, General Chemistry, Biochemistry, Catalysis, POLYMERIZATION, Colloid and Surface Chemistry, Benzamides, NITROPHENOL, IONIZATION-CONSTANT, POLYMERS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a77e46dc1ca88de9e133e3eb8c0f171
https://doi.org/10.1021/jacs.1c12685

المؤلفون: Johan W. M. Heemskerk, Rory R. Koenen, Alexandra C.A. Heinzmann, Tanja Vajen, Tilman M. Hackeng, Daniëlle Coenen, Judith M.E.M. Cosemans, Mieke F.A. Karel, Dennis Suylen, Nicole Meulendijks, Magdolna Nagy

المساهمون: Biochemie, RS: Carim - B01 Blood proteins & engineering, RS: Carim - B03 Cell biochemistry of thrombosis and haemostasis, RS: Carim - B04 Clinical thrombosis and Haemostasis

المصدر: Atherosclerosis, 310, 17-25. Elsevier Ireland Ltd

مصطلحات موضوعية: 0301 basic medicine, Integrins, SCOTT-SYNDROME, IMMUNE, Integrin, ADHESION, 030204 cardiovascular system & hematology, ACTIVATION, 03 medical and health sciences, Blood platelets, 0302 clinical medicine, Thrombasthenia, Scott syndrome, medicine, AMINOPHOSPHOLIPID EXPOSURE, SWITCH, Platelet, Platelet activation, Cytoskeleton, MICROVESICLES, OUTSIDE-IN, biology, Chemistry, Actin cytoskeleton, Convulxin, Extracellular vesicles, medicine.disease, MICROPARTICLE FORMATION, 030104 developmental biology, Biophysics, biology.protein, MEMBRANE, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78d20943879dc28ab40d7aaf65bf623
https://doi.org/10.1016/j.atherosclerosis.2020.07.015

المؤلفون: Mark H. M. Vries, Ingrid Dijkgraaf, Johannes H. Ippel, Tanja Vajen, Alexandra C.A. Heinzmann, Remco T. A. Megens, Rory R. Koenen, Stepan S. Denisov, Dennis Suylen, Mark J. Post, Tilman M. Hackeng

المساهمون: Biomedische Technologie, Biochemie, RS: Carim - B01 Blood proteins & engineering, Fysiologie, RS: Carim - V03 Regenerative and reconstructive medicine vascular disease

المصدر: Bioconjugate Chemistry
Bioconjugate Chemistry, 31(3), 948-955. American Chemical Society

مصطلحات موضوعية: Carotid Artery Diseases, EXPRESSION, Saliva, Chemokine, Endothelium, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Inflammation, macromolecular substances, 02 engineering and technology, Tick, 01 natural sciences, Article, Arthropod Proteins, Mice, Ticks, BINDING, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, NEUTROPHILS, Glycosaminoglycans, Pharmacology, ARREST, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, 021001 nanoscience & nanotechnology, biology.organism_classification, 3. Good health, 0104 chemical sciences, medicine.anatomical_structure, ATHEROSCLEROSIS, MONOCYTE RECRUITMENT, Immunology, biology.protein, Endothelium, Vascular, medicine.symptom, 0210 nano-technology, Chemokines, CXC, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78c102be3548721bdf7fc2ac7cb6ef4
https://doi.org/10.1021/acs.bioconjchem.0c00095

المؤلفون: Kevin H. Mayo, Jesús Jiménez-Barbero, Hans-Joachim Gabius, Guihua Tai, M. Álvaro Berbís, F. Javier Cañada, Dennis Suylen, Michelle C. Miller, Hans Ippel, Yi Zheng

المساهمون: Ludwig Maximilians University Munich, Alexander von Humboldt Foundation, Maastricht University, University of Minnesota, Minnesota Medical Foundation, Miller, Michelle C., Cañada, F. Javier, Berbís, Manuel Álvaro, Jiménez-Barbero, Jesús, Gabius, Hans-Joachim, Miller, Michelle C. [0000-0002-7860-5785], Cañada, F. Javier [0000-0003-4462-1469], Berbís, Manuel Álvaro [0000-0002-0331-7762], Jiménez-Barbero, Jesús [0000-0001-5421-8513], Gabius, Hans-Joachim [0000-0003-3467-3900], Biochemie, RS: Carim - B01 Blood proteins & engineering

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Chemmedchem, 16(4), 713-723. John Wiley & Sons Inc.

مصطلحات موضوعية: Glycan, Magnetic Resonance Spectroscopy, Molecular model, Stereochemistry, ANGINEX, Galectins, Allosteric regulation, PROTEIN, 01 natural sciences, Biochemistry, Epitope, Drug design, CHEMICAL-SHIFT ASSIGNMENTS, Structure-Activity Relationship, Phenols, Polysaccharides, Drug Discovery, Calixarene, metastasis, Humans, General Pharmacology, Toxicology and Pharmaceutics, Galectin, Pharmacology, galectin, Binding Sites, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, TUMOR-GROWTH, COLON-CANCER, Organic Chemistry, Blood Proteins, Ligand (biochemistry), ENDOTHELIAL-CELLS, Galectin · metastasis, RELEVANT LECTINS, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, biology.protein, Molecular Medicine, Angiogenesis, N-15 BACKBONE, Calixarenes, INHIBITORS, Heteronuclear single quantum coherence spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27be02d99509deb5d5ffe67010287e3b
http://hdl.handle.net/10261/227819

المؤلفون: Ashok Aspatwar, Claudiu T. Supuran, Ludwig Dubois, Emilie Anduran, Jean-Yves Winum, Philippe Lambin, Silvia Bua, Dennis Suylen, Seppo Parkkila, Nanda-Kumar Parvathaneni, Alessio Nocentini

المساهمون: RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Precision Medicine, Radiotherapie, RS: GROW - R2 - Basic and Translational Cancer Biology

المصدر: Molecules
Volume 25
Issue 10
Molecules, Vol 25, Iss 2347, p 2347 (2020)
Molecules, 25(10):2347, 1-14. Multidisciplinary Digital Publishing Institute (MDPI)

مصطلحات موضوعية: carbonic anhydrase, Pharmaceutical Science, Analytical Chemistry, 0302 clinical medicine, Neoplasms, Drug Discovery, inhibitors, Tumor Microenvironment, Prodrugs, Carbonic Anhydrase Inhibitors, 0303 health sciences, Sulfonamides, biology, Molecular Structure, Chemistry, Prodrug, 3. Good health, Isoenzymes, TARGET, Biochemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Toxicity, Molecular Medicine, INDUCIBLE FACTORS, HT29 Cells, Gene isoform, hypoxic tumour, Isozyme, Article, lcsh:QD241-441, 03 medical and health sciences, Structure-Activity Relationship, Downregulation and upregulation, lcsh:Organic chemistry, Antigens, Neoplasm, Carbonic anhydrase, Humans, Physical and Theoretical Chemistry, Carbonic Anhydrase IX, 030304 developmental biology, Cell Proliferation, Organic Chemistry, HCT116 Cells, Cytosol, hypoxia-activated prodrug, Cancer cell, biology.protein, Tumor Hypoxia, IX

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af34afdfe6e5a64a32bcbef28c8d5eed
https://pubmed.ncbi.nlm.nih.gov/32443462

المؤلفون: Barend Mees, S.H.E. van der Beelen, Kanin Wichapong, Tilman M. Hackeng, Henri M. H. Spronk, Dennis Suylen, S.M. Agten, J. Hrdinova

المساهمون: Biochemie, RS: Carim - B01 Blood proteins & engineering, RS: Carim - B02 Vascular aspects thrombosis and Haemostasis, MUMC+: MA Med Staf Spec Vaatchirurgie (9), Vascular Surgery, RS: Carim - V03 Regenerative and reconstructive medicine vascular disease, Interne Geneeskunde, RS: Carim - B04 Clinical thrombosis and Haemostasis

المصدر: Thrombosis Research, 207, 66-66. Elsevier Science

مصطلحات موضوعية: business.industry, TISSUE-FACTOR ACTIVITY, Cancer research, Medicine, FACTOR-XIA, Factor XIa, Hematology, THROMBIN GENERATION, business, Thrombin generation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92227761bc236d9d0cf4cb523957ecc8
https://cris.maastrichtuniversity.nl/en/publications/6a439986-56e3-4936-ae1c-22efb1a3c3db

المؤلفون: Michelle A. Berny-Lang, Paola E. J. van der Meijden, Judith M.E.M. Cosemans, Johan W. M. Heemskerk, Constance C.F.M.J. Baaten, Yvonne M. C. Henskens, Tilman M. Hackeng, Frauke May, Owen J. T. McCarty, Marc W. Nolte, Dennis Suylen, Frauke Swieringa, Tom G. Mastenbroek, Nadine J.A. Mattheij, Erik A M Beckers

المساهمون: Promovendi CD, Biochemie, RS: CARIM - R1.03 - Cell biochemistry of thrombosis and haemostasis, RS: CARIM - R1.04 - Clinical thrombosis and haemostasis, Med Microbiol, Infect Dis & Infect Prev, MUMC+: DA CDL Algemeen (9), MUMC+: MA Hematologie (9), RS: CARIM - R1.01 - Blood proteins & engineering

المصدر: Haematologica-the Hematology Journal, 101(4), 427-436. Ferrata Storti Foundation

مصطلحات موضوعية: 0301 basic medicine, Blood Platelets, Primary Cell Culture, Phosphatidylserines, Platelet Glycoprotein GPIIb-IIIa Complex, 030204 cardiovascular system & hematology, Fibrin, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Thrombin, Crotalid Venoms, medicine, Animals, Humans, Platelet, Lectins, C-Type, Platelet activation, Blood Coagulation, Mice, Knockout, biology, Factor XIII, Chemistry, Fibrinogen binding, Fibrinogen, Hematology, Platelet Activation, Molecular biology, 030104 developmental biology, Coagulation, Biochemistry, Factor Va, Molecular Probes, Factor Xa, biology.protein, medicine.drug, Protein Binding, Thrombasthenia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129106d7f22cee86f3d00e2d9c3ae183
https://cris.maastrichtuniversity.nl/en/publications/191a4329-29d5-4c24-a843-b74e1555d428

المؤلفون: Tilman M. Hackeng, Stijn M. Agten, Dennis Suylen

المساهمون: Biochemie, Promovendi CD, RS: CARIM - R1.01 - Blood proteins & engineering

المصدر: Bioconjugate Chemistry, 27(1), 42-46. American Chemical Society

مصطلحات موضوعية: Lysine, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Peptide, Conjugated system, Ligands, 010402 general chemistry, 01 natural sciences, Chemical reaction, Catalysis, chemistry.chemical_compound, Freezing, Oximes, Organic chemistry, Chemokine CCL5, Pharmacology, chemistry.chemical_classification, Aqueous solution, 010405 organic chemistry, Ligand, Organic Chemistry, Temperature, Water, Hydrogen-Ion Concentration, Ketones, Oxime, Combinatorial chemistry, 0104 chemical sciences, Butyrates, chemistry, Thermodynamics, Peptides, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432329a4c256b3b1a54a7cf444a4a1cb
https://doi.org/10.1021/acs.bioconjchem.5b00611