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المؤلفون: Jeffrey J. Jackson, Grant M. Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Dirk G. Brockstedt, Cyril Bucher, Minna Bui, Cynthia Cho, Christoph Colas, Gene Cutler, Adrian Dukes, Xinping Han, Dennis X. Hu, Scott Jacobson, Paul D. Kassner, George E. Katibah, Michelle Yoo Min Ko, Urvi Kolhatkar, Paul R. Leger, Anqi Ma, Lisa Marshall, Jack Maung, Andrew A. Ng, Akinori Okano, Deepa Pookot, Daniel Poon, Chandru Ramana, Maureen K. Reilly, Omar Robles, Jacob B. Schwarz, Anton A. Shakhmin, Hunter P. Shunatona, Raashi Sreenivasan, Parcharee Tivitmahaisoon, Mengshu Xu, Thant Zaw, David J. Wustrow, Mikhail Zibinsky
المصدر: Journal of Medicinal Chemistry. 65:12895-12924
مصطلحات موضوعية: Mice, Knockout, Mice, eIF-2 Kinase, Myeloid-Derived Suppressor Cells, T-Lymphocytes, Drug Discovery, Animals, Molecular Medicine, Heme, Protein Serine-Threonine Kinases
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المؤلفون: Paul D. Kassner, Dirk G. Brockstedt, David Wustrow, Jacob Schwarz, Christophe Colas, Jack Maung, Akinori Okano, Xinping Han, Nathan Kozon, Delia Bradford, Lisa A. Marshall, Silpa Suthram, Kyle Young, Betty Abraham, Deepa Pookot, Niket Shah, Jerick Sanchez, Steve T. Wong, Scott Jacobson, Cynthia Cho, Payal Rana, Berenger Biannic, Dennis X. Hu, Paul R. Leger, Gene Cutler, Michael T. Sun, Yamini M. Ohol
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f989ee2cc8256a47675f17613ed482
https://doi.org/10.1158/1535-7163.22518810 -
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المؤلفون: Paul D. Kassner, Dirk G. Brockstedt, David Wustrow, Jacob Schwarz, Christophe Colas, Jack Maung, Akinori Okano, Xinping Han, Nathan Kozon, Delia Bradford, Lisa A. Marshall, Silpa Suthram, Kyle Young, Betty Abraham, Deepa Pookot, Niket Shah, Jerick Sanchez, Steve T. Wong, Scott Jacobson, Cynthia Cho, Payal Rana, Berenger Biannic, Dennis X. Hu, Paul R. Leger, Gene Cutler, Michael T. Sun, Yamini M. Ohol
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2553fdd80c98dcbf6dde06a2115d9b1f
https://doi.org/10.1158/1535-7163.c.6542127.v1 -
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المؤلفون: Paul D. Kassner, Dirk G. Brockstedt, David Wustrow, Jacob Schwarz, Christophe Colas, Jack Maung, Akinori Okano, Xinping Han, Nathan Kozon, Delia Bradford, Lisa A. Marshall, Silpa Suthram, Kyle Young, Betty Abraham, Deepa Pookot, Niket Shah, Jerick Sanchez, Steve T. Wong, Scott Jacobson, Cynthia Cho, Payal Rana, Berenger Biannic, Dennis X. Hu, Paul R. Leger, Gene Cutler, Michael T. Sun, Yamini M. Ohol
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608a87c8b9624888e8b1c3a5ac3f572b
https://doi.org/10.1158/1535-7163.22518816.v1 -
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المؤلفون: Jacob Bradley Schwarz, Christophe Colas, Paul D. Kassner, Betty Abraham, Delia Bradford, Michael T. Sun, Lisa A. Marshall, Akinori Okano, Dennis X. Hu, Gene Cutler, Payal Rana, Paul Leger, David J. Wustrow, Cynthia Cho, Jack Maung, Yamini M. Ohol, Deepa Pookot, Nathan Kozon, Steve Wong, Scott Jacobson, Niket Shah, Berenger Biannic, Xinping Han, Silpa Suthram, Jerick Sanchez, Dirk G. Brockstedt, Kyle Young
المصدر: Molecular Cancer Therapeutics. 19:1970-1980
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, biology, Oncogene, Chemistry, Wild type, Repressor, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Cell culture, In vivo, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Epigenetics, PRC2, PI3K/AKT/mTOR pathway
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dae990d4fa027b4e7e2e007c01412665
https://doi.org/10.1158/1535-7163.mct-20-0184 -
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المؤلفون: Aparna Jorapur, Lisa A. Marshall, Scott Jacobson, Mengshu Xu, Sachie Marubayashi, Mikhail Zibinsky, Dennis X. Hu, Omar Robles, Jeffrey J. Jackson, Valentin Baloche, Pierre Busson, David Wustrow, Dirk G. Brockstedt, Oezcan Talay, Paul D. Kassner, Gene Cutler
المصدر: PLoS Pathogens, Vol 18, Iss 1, p e1010200 (2022)
PLoS Pathogensمصطلحات موضوعية: Epstein-Barr Virus Infections, Herpesvirus 4, Human, T-Lymphocytes, Regulatory, Mice, Neoplasms, hemic and lymphatic diseases, Cellular types, Medicine and Health Sciences, Biology (General), Pathology and laboratory medicine, Nasopharyngeal Carcinoma, Chemotaxis, Immune cells, Regulatory T cells, Medical microbiology, Hodgkin Disease, Cell Motility, Oncology, Viruses, White blood cells, Heterografts, Chemokines, Pathogens, Research Article, Blood cells, Herpesviruses, QH301-705.5, Immunology, T cells, Antigen-Presenting Cells, Microbiology, Virology, Gastrointestinal Tumors, Genetics, Epstein-Barr virus, Animals, Humans, Molecular Biology, Chemokine CCL22, Carcinoma, Organisms, Viral pathogens, Cancers and Neoplasms, Biology and Life Sciences, Nasopharyngeal Neoplasms, Cell Biology, Dendritic Cells, RC581-607, Microbial pathogens, Gastric Cancer, Animal cells, Head and Neck Cancers, Parasitology, Chemokine CCL17, Immunologic diseases. Allergy, DNA viruses
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المؤلفون: Scott Jacobson, Dennis X. Hu, Cesar Meleza, Mikhail Zibinsky, Ashkaan Younai, Erin Riegler, Omar Robles, Jenny McKinnell, Emily Karbarz, Paul D. Kassner, Lisa A. Marshall, Maureen Kay Reilly, David Chian, Gene Cutler, David J. Wustrow, Dirk G. Brockstedt, Hunter P. Shunatona, Raymond Diokno, Angela Wadsworth, John M. Ketcham, Oezcan Talay, Jeffrey J. Jackson
المصدر: Journal of Medicinal Chemistry. 63:8584-8607
مصطلحات موضوعية: Chemokine, Receptors, CCR4, Population, CCR4, Antineoplastic Agents, chemical and pharmacologic phenomena, T-Lymphocytes, Regulatory, 01 natural sciences, 03 medical and health sciences, Chemokine receptor, Dogs, Immune system, Piperidines, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, CCL17, education, 030304 developmental biology, 0303 health sciences, Tumor microenvironment, education.field_of_study, biology, Chemistry, Immune checkpoint, 0104 chemical sciences, Macaca fascicularis, 010404 medicinal & biomolecular chemistry, biology.protein, Cancer research, Azetidines, Molecular Medicine, sense organs
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المؤلفون: Shumei Wang, Jodie Pang, Heidi J.A. Wallweber, Leah Schutt, Michael Siu, Steven T. Staben, Christopher J. Sneeringer, Yunli Wang, Aditya Murthy, Dennis X. Hu, Yoana N. Dimitrova, Madeleine S. Prangley, Grace Ka Yan Chan, Erin McNamara, Laurent Salphati, Haochu Huang, Huifen Chen, Yong Chen, Snahel Patel, Kai C. Wu, Wensheng Zhao, John Moffat, Junghyun Lim, Joanna Y. Lee
المصدر: Journal of medicinal chemistry. 65(17)
مصطلحات موضوعية: Chemistry, Endosome, Kinase, fungi, Antineoplastic Agents, Endosomes, Pharmacology, Class III Phosphatidylinositol 3-Kinases, Bioavailability, Residue (chemistry), In vivo, Drug Discovery, Autophagy, Molecular Medicine, Potency, Structure based, Kinase activity, Phosphatidylinositol 3-Kinase, Phosphorylation
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المؤلفون: Deepa Pookot, Scott Jacobson, John M. Ketcham, David Chian, Emily Karbarz, Dennis X. Hu, James Ross Walker, Gene Cutler, Ashkaan Younai, Mikhail Zibinsky, Raymond Diokno, David J. Wustrow, Betty Abraham, Angela Wadsworth, Maureen Kay Reilly, Cesar Meleza, Jenny McKinnell, Jeffrey J. Jackson, Abood Okal, Paul D. Kassner, Lisa A. Marshall, Oezcan Talay, Berenger Biannic, Bui Minna H T, Hilary Plake Beck, Hunter P. Shunatona, Omar Robles
المصدر: Journal of Medicinal Chemistry. 62:6190-6213
مصطلحات موضوعية: 0303 health sciences, Tumor microenvironment, education.field_of_study, Chemistry, Effector, Population, FOXP3, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Immune system, In vivo, Drug Discovery, Cancer research, Molecular Medicine, CCL17, education, CCL22, 030304 developmental biology
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المؤلفون: Deepa Pookot, Payal Rana, Paul D. Kassner, Christopher Higgs, Xinping Han, Berenger Biannic, Betty Abraham, Christophe Colas, Jacob Bradley Schwarz, Akinori Okano, Scott Jacobson, Paul Leger, Michael Sun, Jerick Sanchez, Emily Karbarz, Niket Shah, Cynthia Cho, Steve Wong, Yamini M. Ohol, Minna Bui, David J. Wustrow, Maksim Osipov, Delia Bradford, Dennis X. Hu, Jack Maung, Kyle Young, Dirk G. Brockstedt, Grant M. Shibuya
المصدر: Journal of medicinal chemistry. 63(10)
مصطلحات موضوعية: Allosteric regulation, Mutant, Administration, Oral, Mice, Nude, Antineoplastic Agents, Mice, SCID, Crystallography, X-Ray, 01 natural sciences, law.invention, Ubiquitin-Specific Peptidase 7, 03 medical and health sciences, chemistry.chemical_compound, Mice, Protein structure, Succinimide, In vivo, law, Mice, Inbred NOD, Cell Line, Tumor, Drug Discovery, Animals, Humans, 030304 developmental biology, 0303 health sciences, Chemistry, Wild type, Xenograft Model Antitumor Assays, 0104 chemical sciences, Protein Structure, Tertiary, 010404 medicinal & biomolecular chemistry, Biochemistry, Cell culture, Molecular Medicine, Suppressor