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1دورية أكاديمية
المؤلفون: Laura Abriola, Denton Hoyer, Conor R Caffrey, David L Williams, Timothy P Yoshino, Jon J Vermeire
المصدر: PLoS ONE, Vol 14, Iss 6, p e0217019 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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المؤلفون: Sateja Paradkar, Adam Hendricson, Mark Plummer, Ranjini K. Sundaram, James Herrington, Denton Hoyer, Ranjit S. Bindra, Yulia V. Surovtseva, Piyasena Hewawasam
المصدر: Oncotarget
مصطلحات موضوعية: Radiosensitizer, Mibefradil, Cardiotoxicity, biology, business.industry, DNA repair, DNA Repair Inhibition, hERG, glioblastoma, mibefradil, DNA Repair Pathway, alternative non-homologous end joining, Oncology, biology.protein, Cancer research, Medicine, radiosensitizers, business, PI3K/AKT/mTOR pathway, Research Paper, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b96f25b0746c867fcdee576b3c9434
https://doi.org/10.18632/oncotarget.27933 -
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المؤلفون: Krisztina M. Papp-Wallace, Focco van den Akker, Mark Plummer, Barry N. Kreiswirth, Christopher R. Bethel, Elizabeth J. Spencer, Vijay Kumar, Michael R. Jacobs, Steven H. Marshall, Robert A. Bonomo, Federico Perez, Andrea M. Hujer, Denton Hoyer, Kristine M. Hujer, Joel Goldberg, David van Duin
المصدر: European journal of medicinal chemistry. 220
مصطلحات موضوعية: Acinetobacter baumannii, Penicillin binding proteins, Lactams, Klebsiella pneumoniae, medicine.drug_class, Antibiotics, Siderophores, Microbial Sensitivity Tests, medicine.disease_cause, 01 natural sciences, Meropenem, Microbiology, 03 medical and health sciences, Structure-Activity Relationship, Drug Resistance, Multiple, Bacterial, Drug Discovery, medicine, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Pseudomonas aeruginosa, Organic Chemistry, General Medicine, Acinetobacter, Antimicrobial, biology.organism_classification, 0104 chemical sciences, Anti-Bacterial Agents, medicine.drug
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المؤلفون: Elizabeth J. Spencer, T. Nicholas Domitrovic, Margaret O'Shea, Susan D. Rudin, Joel Goldberg, Emma K. Marshall, David van Duin, Denton Hoyer, Steven H. Marshall, Michael R. Jacobs, Vijay Kumar, Krisztina M. Papp-Wallace, Christopher R. Bethel, Barry M. Kreiswirth, Latania K. Logan, Mark Plummer, Robert A. Bonomo, Ha Nguyen, Andrea M. Hujer, Anna Cmolik, Kristine M. Hujer, Federico Perez, Focco van den Akker
المصدر: J Med Chem
مصطلحات موضوعية: Siderophore, Lactams, medicine.drug_class, Antibiotics, Siderophores, Microbial Sensitivity Tests, Crystallography, X-Ray, 01 natural sciences, Article, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Hydrolysis, Mice, Bacterial Proteins, Catalytic Domain, Drug Resistance, Multiple, Bacterial, Drug Discovery, Gram-Negative Bacteria, medicine, polycyclic compounds, Moiety, Animals, Penicillin-Binding Proteins, 030304 developmental biology, 0303 health sciences, Binding Sites, Periplasmic space, Gram negative bacilli, 0104 chemical sciences, Anti-Bacterial Agents, Multiple drug resistance, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, chemistry, Pseudomonas aeruginosa, Lactam, Molecular Medicine, Half-Life
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المؤلفون: Ute I. Scholl, Richard P. Lifton, Laura Abriola, Mark Plummer, Chengbiao Zhang, Esther N. Reimer, Barbara I. Kazmierczak, Wen-Hui Wang, Denton Hoyer, Junhui Zhang, Jane S. Merkel
المصدر: Journal of Clinical Investigation. 127:2739-2750
مصطلحات موضوعية: Adenoma, Aldosterone synthase, medicine.medical_specialty, medicine.medical_treatment, Adrenal Gland Neoplasms, Mutation, Missense, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Internal medicine, KCNJ5, medicine, Cytochrome P-450 CYP11B2, Humans, Aldosterone, biology, Chemistry, Adrenal gland, Roxithromycin, General Medicine, medicine.disease, Potassium channel, Neoplasm Proteins, Steroid hormone, HEK293 Cells, medicine.anatomical_structure, Endocrinology, Amino Acid Substitution, G Protein-Coupled Inwardly-Rectifying Potassium Channels, biology.protein, Macrolides, Research Article, medicine.drug
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6
المؤلفون: Denton Hoyer, Jon J. Vermeire, David L. Williams, Conor R. Caffrey, Laura Abriola, Timothy P. Yoshino
المصدر: PLoS ONE, Vol 14, Iss 6, p e0217019 (2019)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Life Cycles, Oviposition, Drug Evaluation, Preclinical, Pharmacology, Toxicology, Pathology and Laboratory Medicine, HeLa, Larvae, Drug Discovery, Medicine and Health Sciences, Nematode Infections, Anthelmintics, Multidisciplinary, Drug discovery, Pharmaceutics, Eukaryota, 030108 mycology & parasitology, Drug development, Toxicity, Medicine, Research Article, Drug Research and Development, Ancylostoma, Science, Library Screening, Biology, Research and Analysis Methods, 03 medical and health sciences, Drug Therapy, In vivo, Helminths, Parasitic Diseases, Animals, Chemotherapy, Humans, Molecular Biology Techniques, IC50, Molecular Biology, Ancylostoma ceylanicum, Molecular Biology Assays and Analysis Techniques, Hatching, Organisms, Biology and Life Sciences, biology.organism_classification, Invertebrates, High-Throughput Screening Assays, 030104 developmental biology, Hookworms, Developmental Biology, HeLa Cells
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المؤلفون: Hai Xiong, Markus Englert, Dieter Söll, Chenguang Fan, Noah M. Reynolds, Scott J. Miller, Denton Hoyer
المصدر: Angewandte Chemie International Edition. 55:4083-4086
مصطلحات موضوعية: DNA Replication, 0301 basic medicine, DNA Repair, Chemistry, Lysine, Acetylation, General Chemistry, SAP30, complex mixtures, Article, Catalysis, Enzymes, Bromodomain, 03 medical and health sciences, Histone H3, 030104 developmental biology, Biochemistry, Tandem Mass Spectrometry, Histone methyltransferase, Histone H2A, bacteria, Histone code, Histone deacetylase, Histone octamer
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المؤلفون: Markus Englert, Hai Xiong, Chenguang Fan, Scott J. Miller, Dieter Söll, Denton Hoyer, Noah M. Reynolds
المصدر: Angewandte Chemie. 128:4151-4154
مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Chemistry, General Medicine
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المؤلفون: Michael S. Kinch, Denton Hoyer
المصدر: Drug Discovery Today. 20:1163-1168
مصطلحات موضوعية: Pharmacology, Gerontology, United States Food and Drug Administration, History, 20th Century, Legislation, Drug, History, 21st Century, United States, Drug development, Drug Design, Political science, Drug Discovery, Humans, Marketing, Drug Approval, health care economics and organizations
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المؤلفون: Pierre A. Miranda-Herrera, Sagar R. Shah, Alfredo Quinones-Hinojosa, Andre Levchenko, Hugo Guerrero-Cazares, Natanael Zarco, Onur Kilic, William Hungerford, Farren J. Isaacs, Kyle Mohler, Denton Hoyer, Laura Abriola, Benjamin E. Turk, Natasha L. Pirman, Jesse Rinehart, Svetlana Rogulina, Paula Schiapparelli, Chad J. Miller
المصدر: Cell reports
مصطلحات موضوعية: Male, Mice, Nude, Protein Serine-Threonine Kinases, General Biochemistry, Genetics and Molecular Biology, Article, Substrate Specificity, Small Molecule Libraries, Synthetic biology, chemistry.chemical_compound, Phosphoserine, WNK Lysine-Deficient Protein Kinase 1, Cell Movement, Cell Line, Tumor, Escherichia coli, Animals, Humans, Amino Acid Sequence, Phosphorylation, Expanded genetic code, Cell Proliferation, Chemistry, Kinase, urogenital system, Middle Aged, Genetic code, WNK1, Recombinant Proteins, WNK4, Cell biology, HEK293 Cells, Female, Glioblastoma, Signal Transduction
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