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المؤلفون: Menghao Huang, Kushan Chowdhury, Zhigang Fang, X. Charlie Dong, Ming O. Li, Suthat Liangpunsakul, Hyeong-Geug Kim
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Sestrins, MPO, myeloperoxidase, Mitogen-Activated Protein Kinase Kinase 7, RC799-869, DMSO, dimethyl sulfoxide, FoxO, forkhead box O, Sesn1/2/3, sestrin1/2/3, medicine.disease_cause, TKO, triple knockout, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, GSH, glutathione, Phosphorylation, NF-κB, nuclear factor kappa B, Original Research, Cat, catalase, Mice, Knockout, Sestrin, Gpx3, glutathione peroxidase 3, Il6, interleukin 6, WD, Western diet, biology, Chemistry, Kinase, Fatty liver, Tgfbr1, transforming growth factor beta receptor 1, Gastroenterology, Col1a1, collagen type 1 alpha 1, Nox1, NADPH oxidase 1, Diseases of the digestive system. Gastroenterology, Dgat2, diacylglycerol O-acyltransferase 2, Cell biology, Keap1, Kelch-like ECH-associated protein 1, C-Jun N-Terminal Kinase, Liver, Lipotoxicity, c-Jun N-terminal kinases, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, Disease Susceptibility, Signal transduction, NASH, nonalcoholic steatohepatitis, Gss, glutathione synthetase, Pdgfrb, platelet-derived growth factor receptor beta, Timp1, tissue inhibitor of metalloproteinase 1, Fasn, fatty acid synthase, Fatty Liver Disease, Sod, superoxide dismutase, Acta2, smooth muscle actin alpha 2, ER, endoplasmic reticulum, PA, palmitic acid, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, MKK, mitogen-activated protein kinase kinase, medicine, Animals, Humans, Srebp, sterol regulatory element-binding protein, Protein kinase A, KD, knockdown, MDA, malondialdehyde, Inflammation, KO, knockout, Hepatology, NRF2, nuclear factor erythroid 2-related like 2, JNK Mitogen-Activated Protein Kinases, Lipid Metabolism, medicine.disease, Tgfb1, transforming growth factor beta 1, WT, wild-type, mTORC, mechanistic target of rapamycin complex, Fatty Liver, AMPK, AMP-activated protein kinase, Disease Models, Animal, Oxidative Stress, Scd1, stearoyl-CoA desaturase 1, 030104 developmental biology, Gene Expression Regulation, Cytoprotection, Hepatocytes, biology.protein, BSA, bovine serum albumin, SD, standard deviation, DHE, dihydroethidium, PERK, protein kinase R-like endoplasmic reticulum kinase, Tnf, tumor necrosis factor, Biomarkers, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574bc0f082fa7f7fd23bf88f6f9c6fc
http://www.sciencedirect.com/science/article/pii/S2352345X21000862 -
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المؤلفون: Ruth E. Carmichael, Laura DiGiovanni, Michael Schrader, Peter K. Kim, Rechal Kumar, Beatriz S.C. Silva
المصدر: Biochim Biophys Acta Mol Cell Res
Biochimica et Biophysica Acta. Molecular Cell Researchمصطلحات موضوعية: 0301 basic medicine, Mdm, mitochondrial division and maintenance, FFAT motif, membrane contact sites, Golgi Apparatus, Mitochondrion, PBD, peroxisome biogenesis disorder, PLIN5, perilipin 5 protein, Lysosomal compartment, FFAT, two phenylalanines (FF) in an acidic tract, ERMES, ER-mitochondria encounter structure, 0302 clinical medicine, Num1, nuclear migration protein 1, Lipid droplet, MFF, mitochondrial fission factor, lipid metabolism, Acyl-CoA binding domain containing protein, Osh, oxysterol-binding protein homology, ATF6α, activating transcription factor 6α, Chemistry, TMEM135, transmembrane protein 135, Peroxisome, DRP1, dynamin-related protein 1, Mitochondria, Cell biology, PTPIP51, protein tyrosine phosphatase interacting protein 51, IP3R, 1,4,5-trisphosphate receptor, PM, plasma membrane, INF2, inverted formin 2, symbols, OMM, outer mitochondrial membrane, IMM, inner mitochondrial membrane, Cell physiology, ORP, oxysterol-binding protein related protein, ATP, adenosine triphosphate, TAG, triacylglycerol, MCS, membrane contact site, Endosome, TBC1D15, TBC1 domain family member 15, Endosomes, Article, ACBD, acyl-CoA binding domain containing protein, ER, endoplasmic reticulum, DMT1, divalent metal transporter 1, 03 medical and health sciences, symbols.namesake, ROS, reactive oxygen species, VAP, vesicle-associated membrane protein (VAMP)–associated protein, PEX, peroxin (peroxisome biogenesis factor), Organelle, Peroxisomes, MIGA2, Mitoguardin 2 protein, Humans, ABCD1, ATP binding cassette subfamily D member 1, DGAT2, diacylglycerol O-acyltransferase 2, Molecular Biology, CRAC, calcium release-activated channel, MIRO1, mitochondrial Rho GTPase 1, PI(4)P, phosphatidylinositol-4-phosphate, TGN, trans-Golgi network, Cell Membrane, STARD3, StAR related lipid transfer domain containing protein 3, VPS13, vacuole protein sorting-associated protein 13, Lipid Droplets, Cell Biology, Golgi apparatus, MAM, mitochondria-ER association membrane, VLCFA, very long-chain fatty acid, PPV, pre-peroxisomal vesicle, OSBP, oxysterol-binding protein, 030104 developmental biology, PI(4,5)P2, phosphatidylinositol-4,5-bisphosphate, Lysosomes, 030217 neurology & neurosurgery, NPC1, Niemann-Pick C1 protein
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المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze
المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase
وصف الملف: application/pdf
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المؤلفون: Hong-Min Ni, Wen-Xing Ding, Xiaojuan Chao
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 885-886 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: HFD, high-fat diet, S100A11, S100 calcium binding protein A11, Datasets as Topic, CIDEC, cell death-inducing DFFA-like effector c, Mice, RFP, red fluorescent protein, HFHC, high-fat and high-cholesterol diet, Non-alcoholic Fatty Liver Disease, LDL-c, low-density lipoprotein c, HDAC6, histone deacetylase 6, TBA, tubastatin A, Medicine, co-IP, co-immunoprecipitation, Original Research, TG, triglyceride, Forkhead Box Protein O1, Liver Diseases, FOXO1, S100 Proteins, Fatty liver, Gastroenterology, ATG7, autophagy related 7, mRNA, messenger RNA, Up-Regulation, Gene Expression Regulation, Neoplastic, HFLC, high-fat low-cholesterol, Editorial, Liver, LD, lipid droplets, CON, control, Ac-FOXO1, acetylated forkhead box O1, LC3-II, LC3-phosphatidylethanolamine conjugate, qPCR, quantitative polymerase chain reaction, SILAC, stable isotope labeling technology of amino acids in cell culture, Signal Transduction, SDS, sodium dodecyl sulfate, PBS, phosphate-buffered saline, Mice, Transgenic, Diet, High-Fat, FOXO1, forkhead box O1, CE, cholesterol ester, SIRT1, Sirtuin 1, Text mining, Cell Line, Tumor, NAFLD, Autophagy, Animals, Humans, lcsh:RC799-869, DGAT2, diacylglycerol O-acyltransferase 2, GRB2, growth factor receptor-bound protein 2, Hepatology, business.industry, Lipogenesis, Tupaiidae, OA, oleic acid, Lipid Metabolism, medicine.disease, WT, wild-type, Disease Models, Animal, MS, mass spectrometry, S100A11, CRISPR/Cas9, clustered regularly interspaced short palindromic repeats/cas9, Hepatocytes, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1287515fb220d00a7c882d49e29bf5ca
http://www.sciencedirect.com/science/article/pii/S2352345X20301922
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