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1
المؤلفون: Charles William Mann, Lloyd M. Garrick, Matthew D. Vera, Linda Shanno, Jeffrey C. Pelletier, John F. Rogers, Diane B. Hauze, Jay E. Wrobel, Daniel M. Green, Irene Feingold, Murty Chengalvala, John F. Mehlmann, Joseph T. Lundquist, Joshua E. Cottom
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2512-2515
مصطلحات موضوعية: Male, medicine.medical_specialty, Benzimidazole, medicine.drug_class, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Gonadotropin-releasing hormone, Pharmacology, Biochemistry, Piperazines, Gonadotropin-releasing hormone antagonist, Rats, Sprague-Dawley, chemistry.chemical_compound, Heterocyclic Compounds, Internal medicine, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Cells, Cultured, G protein-coupled receptor, Chemistry, Organic Chemistry, Biological activity, In vitro, Rats, Endocrinology, Molecular Medicine, Antagonism, Receptors, LHRH, Half-Life
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2
المؤلفون: Weiguang Zhao, Raymond Unwalla, Frederick J. Bex, Richard J. Murrills, John A. Robinson, Nippa Alon, Usha Varadarajan, Paul J. Yaworsky, Adam M. Gilbert, Valerie E. Coleburn, Virginia Gironda, Diane B. Hauze, Matthew Kirisits, Michael C. Sharp, Paula Green, Yao-Bin Liu, Yogendra P. Kharode, Girija Krishnamurthy, Matthew Gregory Bursavich, Bheem M. Bhat, Michael Cain, Sabrina Lombardi, Jeanne J. Matteo, Sally Selim, Ho-Sun Lam
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:366-370
مصطلحات موضوعية: Recombinant Fusion Proteins, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Wnt3 Protein, Glycogen Synthase Kinase 3, Mice, In vivo, Cell Line, Tumor, Wnt3A Protein, Drug Discovery, Animals, Humans, Molecular Biology, GSK3B, beta Catenin, Bone Development, Glycogen Synthase Kinase 3 beta, Chemistry, Skull, Organic Chemistry, Imidazoles, Wnt signaling pathway, Transfection, Hit to lead, In vitro, Cell biology, Mice, Inbred C57BL, Wnt Proteins, Pyrimidines, Catenin, Intercellular Signaling Peptides and Proteins, Molecular Medicine, Signal transduction, Signal Transduction
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3
المؤلفون: Diane B. Hauze, Michael C. Sharp, Bheem M. Bhat, Paula Green, Colleen Milligan, Daniel M. Green, Jennifer Pirrello, Peter V.N. Bodine, Ronald L. Magolda, Adam M. Gilbert, Matthew D. Vera, Yogendra P. Kharode, Valerie E. Coleburn, Luciana De Araujo Felix, Mattew G. Bursavich, Nipa Alon, Jeanne J. Matteo, Jay Wrobel, Frederick J. Bex, Jeffrey C. Pelletier, Susan Lockhead, Joseph T. Lundquist, Richard J. Murrills, Ray Unwalla, Paul J. Yaworsky, Sally Selim, John F. Mehlmann, Ho-Sun Lam
المصدر: Journal of Medicinal Chemistry. 52:6962-6965
مصطلحات موضوعية: Models, Molecular, Agonist, medicine.drug_class, Pharmacology, Glycogen Synthase Kinase 3, Mice, Piperidines, Pharmacokinetics, Osteogenesis, Oral administration, Catalytic Domain, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, beta Catenin, Glycogen Synthase Kinase 3 beta, Chemistry, Wnt signaling pathway, Small molecule, In vitro, Rats, Wnt Proteins, Pyrimidines, Biochemistry, Catenin, Ovariectomized rat, Molecular Medicine, Signal Transduction
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المؤلفون: Lloyd M. Garrick, John F. Mehlmann, Diane B. Hauze, Joshua E. Cottom, Daniel M. Green, Jeffrey C. Pelletier, Murty Chengalvala, Irene Feingold, Joseph T. Lundquist, John F. Rogers, Charles William Mann, Linda Shanno, Jay E. Wrobel, Christine Huselton, Wenling Kao, Kees Kenneth L
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:1986-1990
مصطلحات موضوعية: medicine.medical_specialty, Benzimidazole, Time Factors, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Gonadotropin-releasing hormone, Peptide hormone, Biochemistry, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, Heterocyclic Compounds, Oral administration, Internal medicine, Drug Discovery, medicine, Animals, Receptor, Molecular Biology, Volume of distribution, Chemistry, Organic Chemistry, Antagonist, Luteinizing Hormone, Rats, Bioavailability, Endocrinology, Models, Animal, Molecular Medicine, Benzimidazoles, Receptors, LHRH
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5
المؤلفون: William R. Adams, Irene Feingold, John F. Mehlmann, Cesario O Tio, Joshua E. Cottom, Jay E. Wrobel, Jeffrey C. Pelletier, Daniel M. Green, John F. Rogers, James W. Jetter, Murty Chengalvala, Joseph T. Lundquist, Charles William Mann, Linda Shanno, Ronald L. Magolda, Diane B. Hauze, Gregory S. Kopf, Christine Huselton
المصدر: Journal of Medicinal Chemistry. 52:2148-2152
مصطلحات موضوعية: Male, Stereochemistry, Administration, Oral, Biological Availability, In Vitro Techniques, Binding, Competitive, Chemical synthesis, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Quinoxaline, Oral administration, Quinoxalines, Drug Discovery, Animals, Humans, Structure–activity relationship, Receptor, Antagonist, Luteinizing Hormone, Rats, chemistry, Pituitary Gland, Microsomes, Liver, Molecular Medicine, Benzimidazoles, Pharmacophore, Orchiectomy, Receptors, LHRH, Gonadotropin-releasing hormone receptor, Half-Life
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6
المؤلفون: Murty V. Chengalvala, Linda Shanno, Charles William Mann, Josh Cottom, Diane B. Hauze, Jay E. Wrobel, Irene Feingold, Jeffrey C. Pelletier, Gregory S. Kopf, Daniel M. Green, John A. Rogers, Wenling Kao, Christine Huselton, John F. Mehlmann, Joseph T. Lundquist, Lloyd M. Garrick, James W. Jetter
المصدر: Bioorganic & Medicinal Chemistry. 16:6617-6640
مصطلحات موضوعية: Male, endocrine system, medicine.medical_specialty, medicine.drug_class, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Gonadotropin-releasing hormone, Methylation, Biochemistry, Piperazines, Gonadotropin-releasing hormone antagonist, Rats, Sprague-Dawley, Structure-Activity Relationship, Prostate cancer, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Receptor, Piperazine, Molecular Biology, Leuteinizing hormone, Molecular Structure, Chemistry, Organic Chemistry, Antagonist, Luteinizing Hormone, medicine.disease, Glycolates, Rats, Cross-Linking Reagents, Endocrinology, Molecular Medicine, Benzimidazoles, Receptors, LHRH, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: Kees Kenneth L, Valerie E. Coleburn, Frederick J. Bex, Horace Fletcher, Bheem M. Bhat, Jeanne J. Matteo, Richard J. Murrills, Charles William Mann, Diane B. Hauze
المصدر: Letters in Drug Design & Discovery. 2:201-204
مصطلحات موضوعية: Biochemistry, biology, Chemistry, Drug Discovery, Aspartic acid, biology.protein, Pharmaceutical Science, Molecular Medicine, Vitronectin, In vitro
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa51cedc0eef3cefda7e99a59354d7cd
https://doi.org/10.2174/1570180053765110 -
8
المصدر: Canadian Journal of Chemistry. 79:1632-1654
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Ninhydrin, Reagent, Organic Chemistry, Organic chemistry, General Chemistry, Combinatorial chemistry, Catalysis, Amino acid
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9
المؤلفون: Rajarathnam E. Reddy, Joanna M. Szewczyk, Kelly K. Schumacher, Franklin A. Davis, Madeleine M. Joullié, Diane B. Hauze, Jianjun Jiang
المصدر: Tetrahedron Letters. 40:455-458
مصطلحات موضوعية: chemistry.chemical_classification, chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Total synthesis, Organic chemistry, Biochemistry, Highly sensitive, Amino acid
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10
المصدر: Tetrahedron. 53:4239-4246
مصطلحات موضوعية: chemistry.chemical_classification, Organic Chemistry, Salt (chemistry), chemistry.chemical_element, Zinc, Biochemistry, Medicinal chemistry, Amino acid, Fluorescence intensity, chemistry.chemical_compound, chemistry, Ninhydrin, Yield (chemistry), Drug Discovery, Glycine