نتائج البحث - "Diego Hernán Rayes"

1

Drug discovery: Insights from the invertebrate Caenorhabditis elegans

المؤلفون: Sebastián Giunti, Natalia Denise Andersen, Maria Jose de Rosa, Diego Hernán Rayes

المصدر: Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Pharmacology Research & Perspectives

مصطلحات موضوعية: Drug, C. ELEGANS, media_common.quotation_subject, Drug Evaluation, Preclinical, PHARMACOLOGICAL SCREENINGS, Computational biology, RM1-950, 030226 pharmacology & pharmacy, drug discovery, purl.org/becyt/ford/1 [https], 03 medical and health sciences, 0302 clinical medicine, Species Specificity, GENETIC SCREENINGS, Animals, Humans, human disease models, Invited Reviews, General Pharmacology, Toxicology and Pharmaceutics, Pharmaceutical sciences, pharmacological screenings, Caenorhabditis elegans, purl.org/becyt/ford/1.6 [https], media_common, Invited Review, biology, Drug discovery, HUMAN DISEASE MODELS, biology.organism_classification, High-Throughput Screening Assays, DRUG DISCOVERY, genetic screenings, Neurology, Drug development, 030220 oncology & carcinogenesis, Models, Animal, C. elegans, Therapeutics. Pharmacology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb9370dbd64cf2304060b7065a64249
https://doaj.org/article/0dfd02d097f04684851889f4db9c2339

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2

Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans

المؤلفون: Hee June Choi, Douglas K. Reilly, Elizabeth M. DiLoreto, Mark J. Alkema, Diego Hernán Rayes, Ying K. Zhang, Christopher D. Chute, Veronica L. Coyle, Frank C. Schroeder, Jagan Srinivasan

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, Cell Communication, Olfactory receptors, 02 engineering and technology, Biology, Article, Tyra-2, General Biochemistry, Genetics and Molecular Biology, Ciencias Biológicas, purl.org/becyt/ford/1 [https], pheromone, 03 medical and health sciences, chemistry.chemical_compound, Calcium imaging, Receptors, Biogenic Amine, Cellular neuroscience, Biogenic amine, Avoidance Learning, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, purl.org/becyt/ford/1.6 [https], lcsh:Science, Neurotransmitter, Receptor, Octopamine, chemistry.chemical_classification, Multidisciplinary, communication, behavior, Nociceptors, General Chemistry, Octopamine (drug), Bioquímica y Biología Molecular, 021001 nanoscience & nanotechnology, Cell biology, 030104 developmental biology, chemistry, lcsh:Q, Ectopic expression, Signal transduction, 0210 nano-technology, CIENCIAS NATURALES Y EXACTAS, Signal Transduction

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7227699c555ecee37a438e76134fa94
https://doi.org/10.1038/s41467-019-11240-7

Find this article in full text from ProQuest

3

Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in Caenorhabditis elegans

المؤلفون: Yasunori Saheki, Mei Zhen, Shangbang Gao, Mark J. Alkema, Yung-Chi Huang, Jennifer K. Pirri, Michael M. Francis, Jeff Grant, Ben Mulcahy, Diego Hernán Rayes

المساهمون: Lee Kong Chian School of Medicine (LKCMedicine)

المصدر: eLife, Vol 8 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: 0301 basic medicine, medicine.disease_cause, purl.org/becyt/ford/1 [https], GABA, 0302 clinical medicine, CaV2, neurotransmission, Biology (General), Familial hemiplegic migraine, Caenorhabditis elegans, Mutation, Voltage-dependent calcium channel, biology, Chemistry, General Neuroscience, General Medicine, Bioquímica y Biología Molecular, 3. Good health, Cell biology, Caenorhabditis Elegans, Excitatory postsynaptic potential, C. elegans, Medicine, CIENCIAS NATURALES Y EXACTAS, QH301-705.5, Science, Neurotransmission, Inhibitory postsynaptic potential, General Biochemistry, Genetics and Molecular Biology, Ciencias Biológicas, 03 medical and health sciences, medicine, Medicine [Science], purl.org/becyt/ford/1.6 [https], calcium, General Immunology and Microbiology, behavior, fungi, medicine.disease, biology.organism_classification, Hyperactivity, acetylcholine, UNC-2/CaV2a, 030104 developmental biology, ion channel, Cholinergic, Gain of function, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66b311fa1464fd1a79fda9e6334afe1
https://elifesciences.org/articles/45905

4

Author response: Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in Caenorhabditis elegans

المؤلفون: Mei Zhen, Ben Mulcahy, Yasunori Saheki, Yung-Chi Huang, Diego Hernán Rayes, Shangbang Gao, Jennifer K. Pirri, Jeff Grant, Michael M. Francis, Mark J. Alkema

مصطلحات موضوعية: Physics, Gain of function, biology, Biophysics, Neurotransmission, biology.organism_classification, Excitation, Caenorhabditis elegans, Communication channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::854a497735551d78febc1975de57f23d
https://doi.org/10.7554/elife.45905.034

5

Gain-of-function mutations in the UNC-2/CaV2α channel lead to hyperactivity and excitation-dominant synaptic transmission in Caenorhabditis elegans

المؤلفون: Ben Mulcahy, Yasunori Saheki, Jennifer K. Pirri, Shangbang Gao, Diego Hernán Rayes, Mei Zhen, Yung-Chi Huang, Jeff Grant, Michael M. Francis, Mark J. Alkema

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c06f35882400208bbd4757e93969d19
https://doi.org/10.1101/509380

6

Diisopropylphenyl-imidazole (DII): A new compound that exerts anthelmintic activity through novel molecular mechanisms

المؤلفون: Maria Gabriela Blanco, Andres Garelli, Maria Jose de Rosa, Gustavo F. Silbestri, Maria Soledad Vela Gurovic, Diego Hernán Rayes, Sebastián Giunti

المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0007021 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: 0301 basic medicine, Bacterial Lethality, Male, Life Cycles, Nematoda, Mutant, RC955-962, Receptors, Nicotinic, Pathology and Laboratory Medicine, purl.org/becyt/ford/1 [https], Larvae, Arctic medicine. Tropical medicine, Anthelmintic, Medicine and Health Sciences, Receptor, Caenorhabditis elegans, Nematode, Anthelmintics, biology, Molecular Structure, Organic Compounds, Drosophila Melanogaster, Imidazoles, Eukaryota, Animal Models, 3. Good health, Cell biology, Mutant Strains, Insects, Chemistry, Infectious Diseases, Bioassays and Physiological Analysis, Experimental Organism Systems, Caenorhabditis Elegans, Physical Sciences, C. elegans, Drosophila, Female, Drosophila melanogaster, Public aspects of medicine, RA1-1270, CIENCIAS NATURALES Y EXACTAS, Muscle Electrophysiology, medicine.drug, Research Article, Arthropoda, Cell Survival, Research and Analysis Methods, Microbiology, Ciencias Biológicas, 03 medical and health sciences, Model Organisms, Signs and Symptoms, Biología Celular, Microbiología, Diagnostic Medicine, medicine, Genetics, Animals, Paralysis, Humans, purl.org/becyt/ford/1.6 [https], Caenorhabditis elegans Proteins, Gene, Imidazole, HEK 293 cells, Organic Chemistry, Electrophysiological Techniques, Public Health, Environmental and Occupational Health, Organisms, Chemical Compounds, Biology and Life Sciences, Bacteriology, biology.organism_classification, Invertebrates, 030104 developmental biology, HEK293 Cells, Mutation, Animal Studies, Caenorhabditis, Developmental Biology