المؤلفون: Sara A Litwak, Kim Loh, Andreas Strasser, Esteban Nicolas Gurzov, Helen E. Thomas, Jibran A Wali, Claudia Selck, William J Stanley, Evan G Pappas

المصدر: Scientific Reports
Scientific reports, 6

مصطلحات موضوعية: 0301 basic medicine, Leptin, Male, medicine.medical_treatment, Adipose tissue, Insulin -- pharmacology, Recombinant Proteins -- pharmacology, chemistry.chemical_compound, Eating, Mice, 0302 clinical medicine, Puma, Adipocyte, Glucose homeostasis, Body Weight -- physiology, Homeostasis, Insulin, Adipose Tissue -- pathology, 2. Zero hunger, Mice, Knockout, Glucose tolerance test, Multidisciplinary, medicine.diagnostic_test, biology, Sciences bio-médicales et agricoles, Diet, High-Fat -- adverse effects, Recombinant Proteins, Adipose Tissue, Liver, medicine.medical_specialty, Homeostasis -- physiology, Obesity -- pathology -- physiopathology, 030209 endocrinology & metabolism, Diet, High-Fat, Article, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Tumor Suppressor Proteins -- deficiency -- genetics -- physiology, Animals, Obesity, Eating -- physiology, Tumor Suppressor Proteins, Body Weight, Glucose -- metabolism, Glucose Tolerance Test, medicine.disease, biology.organism_classification, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Glucose, chemistry, Apoptosis Regulatory Proteins -- deficiency -- genetics -- physiology, Insulin Resistance, Apoptosis Regulatory Proteins, Liver -- pathology, Leptin -- blood

وصف الملف: 1 full-text file(s): application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2636fb32454440ee72770afbd24bc074
https://pubmed.ncbi.nlm.nih.gov/27033313

المؤلفون: Elisa Fernández-Millán, Manuel Ros, Juan de Toro-Martín, Carmen Álvarez, Teresa Fernández-Agulló, Miriam García-San Frutos, F. Escrivá, Esther Lizárraga-Mollinedo

المصدر: The Journal of biological chemistry, 290 (31

مصطلحات موضوعية: Leptin, Male, Pro-Opiomelanocortin, Overweight, Biochemistry, Pregnancy, Risk Factors, Pro-Opiomelanocortin -- metabolism, Neuropeptide Y, hypothalamus, Adiposity, biology, Prenatal Exposure Delayed Effects -- etiology -- metabolism, Molecular Bases of Disease, Sciences bio-médicales et agricoles, Diet, High-Fat -- adverse effects, Muscle, Skeletal -- metabolism -- pathology, adipose tissue, nutrition, Liver, Prenatal Exposure Delayed Effects, Female, Hypothalamus -- metabolism, medicine.symptom, Oxidation-Reduction, insulin, medicine.medical_specialty, Adipose Tissue, White, Hypothalamus, Cafeteria, Hyperphagia, Diet, High-Fat, leptin, Insulin resistance, Internal medicine, medicine, Animals, Adipose Tissue, White -- metabolism -- pathology, Obesity, Rats, Wistar, Muscle, Skeletal, Molecular Biology, Neuropeptide Y -- metabolism, business.industry, Malnutrition, Liver -- metabolism -- pathology, Obesity -- etiology -- metabolism, Cell Biology, biology.organism_classification, medicine.disease, Hyperphagia -- etiology -- metabolism, undernutrition, Endocrinology, Lean body mass, Leptin -- metabolism, Insulin Resistance, business, Energy Intake, Malnutrition -- complications -- metabolism -- rehabilitation, Body mass index, Dyslipidemia

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e120856c85be702acec844b52824508
https://pubmed.ncbi.nlm.nih.gov/26105051

المؤلفون: Martins, Fernando

المساهمون: Oliveira Júnior, Silvio Assis de

المصدر: Repositório Institucional da UFMS
Universidade Federal de Mato Grosso do Sul (UFMS)
instacron:UFMS

مصطلحات موضوعية: Dislipidemias, Ratos Wistar, Obesidade, Ventricular Remodeling, Dieta Hiperlipídica - efeitos adversos, Hyperglycemia, Remodelação Ventricular, Obesity, Diet, High-Fat - adverse effects, Rats, Wistar, Hiperglicemia, Dyslipidemias

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3056::97aebd17b591c86bff651c8f424a74b6
https://repositorio.ufms.br/handle/123456789/2297

المؤلفون: Alamri, AS, Brock, JA, Herath, CB, Rajapaksha, IG, Angus, PW, Ivanusic, JJ

مصطلحات الفهرس: Animals Blood Glucose/metabolism Diabetes Mellitus, Experimental/complications Diabetes Mellitus, Type 2/*complications Diet, High-Fat/*adverse effects Epithelium, Corneal/*innervation Hyperglycemia/etiology Male Mice Mice, Inbred C57BL Microscopy, Fluorescence Nerve Endings/physiology Nerve Fibers/pathology Nociceptors/*metabolism Streptozocin TRPM Cation Channels/metabolism TRPV Cation Channels/metabolism Thermoreceptors/*metabolism Trigeminal Nerve/*metabolism Trigeminal Nerve Diseases/*etiology/metabolism, 06 Biological Sciences, 11 Medical and Health Sciences, text, Journal Article, JOUR

URL: http://handle.unsw.edu.au/1959.4/unsworks_72085
https://orcid.org/0000-0001-9151-8531
https://orcid.org/0000-0001-9151-8531
Alamri, Abdulhakeem S Brock, James A Herath, Chandana B Rajapaksha, Indu G Angus, Peter W Ivanusic, Jason J eng Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):209-217. doi: 10.1167/iovs.18-25788.Purpose: There is a substantial body of evidence indicating that corneal sensory innervation is affected by pathology in a range of diseases. However, there are no published studies that have directly assessed whether the nerve fiber density of the different subpopulations of corneal sensory neurons are differentially affected. The present study explored the possibility that the intraepithelial nerve fiber density of corneal polymodal nociceptors and cold thermoreceptors are differentially affected in mice fed with a high-fat high cholesterol (HFHC; 21% fat, 2% cholesterol) diet and in those that also have diabetes. Methods: The mice were fed the HFHC diet for the duration of the experiment (up to 40 weeks). Mice in the diabetes group had hyperglycaemia induced with streptozotocin after 15 weeks on the HFHC diet. Age-matched control animals were fed a standard diet. All corneal nerve fibers were labeled with a pan neuronal antibody (antiprotein gene product 9.5), and polymodal nociceptors and cold thermoreceptors were labeled with antibodies directed against transient receptor potential cation channel, subfamily V, member 1 and transient receptor potential cation channel subfamily M member 8, respectively. Results: The mice fed a HFHC diet and those that in addition have hyperglycemia have similar reductions in corneal nerve fiber density consistent with small fiber neuropathy. Importantly, both treatments more markedly affected the intraepithelial axons of cold thermoreceptors than those of polymodal nociceptors. Conclusions: The results provide evidence that distinct subpopulations of corneal sensory neurons can be differentially affected by pathology.
Invest Ophthalmol Vis Sci, 60, 1, 209-217

المؤلفون: Litwak, Sara A, Loh, Kim, Stanley, William J, Pappas, Evan G, Wali, Jibran A, Selck, Claudia, Strasser, Andreas, Thomas, Helen H.E., Gurzov, Esteban Nicolas

المصدر: Scientific reports, 6

مصطلحات الفهرس: Sciences bio-médicales et agricoles, Adipose Tissue -- pathology, Animals, Apoptosis Regulatory Proteins -- deficiency -- genetics -- physiology, Body Weight -- physiology, Diet, High-Fat -- adverse effects, Eating -- physiology, Glucose -- metabolism, Glucose Tolerance Test, Homeostasis -- physiology, Insulin -- pharmacology, Insulin Resistance, Leptin -- blood, Liver -- pathology, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity -- pathology -- physiopathology, Recombinant Proteins -- pharmacology, Tumor Suppressor Proteins -- deficiency -- genetics -- physiology, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/260227/4/doi_243854.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/260227
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المؤلفون: Cheng, Jia, Wang, Dao Wen, Zhou, Jianfeng, Ning, Qin, Chen, Zhishui, Eizirik, Decio L., Zhou, Zhiguang, Zhao, Chunxia, Wang, Cong-Yi, Song, Jia, He, Xiaoyu, Zhang, Meng-Qi, Huo, Shuang, Zhang, Shu, Yu, Qilin, Yang, Ping, Xiong, Fei

المصدر: Diabetes (New York, N.Y.), 65 (11

مصطلحات الفهرس: Métabolisme, Diabétologie, Endocrinologie, Médecine interne, Animals, Blotting, Western, Cells, Cultured, DNA Methylation -- genetics -- physiology, DNA-Binding Proteins -- genetics -- metabolism, Diet, High-Fat -- adverse effects, Energy Metabolism -- genetics -- physiology, Female, Glucose Tolerance Test, Homeostasis -- genetics -- physiology, Humans, In Vitro Techniques, Insulin -- metabolism, Insulin Resistance -- genetics -- physiology, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity -- etiology -- metabolism, Real-Time Polymerase Chain Reaction, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/243751/3/doi_227378.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/243751
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المؤلفون: Lizarraga Mollinedo, Esther, Fernández-Millán, Elisa, García-San Frutos, Miriam, Martín, Juan de Toro Jde T, Fernández-Agulló, Teresa, Ros, Manuel, Alvarez, Carmen, Escrivá, Fernando

المصدر: The Journal of biological chemistry, 290 (31

مصطلحات الفهرس: Sciences bio-médicales et agricoles, Adipose Tissue, White -- metabolism -- pathology, Adiposity, Animals, Diet, High-Fat -- adverse effects, Energy Intake, Female, Hyperphagia -- etiology -- metabolism, Hypothalamus -- metabolism, Insulin Resistance, Leptin -- metabolism, Liver -- metabolism -- pathology, Male, Malnutrition -- complications -- metabolism -- rehabilitation, Muscle, Skeletal -- metabolism -- pathology, Neuropeptide Y -- metabolism, Obesity -- etiology -- metabolism, Oxidation-Reduction, Pregnancy, Prenatal Exposure Delayed Effects -- etiology -- metabolism, Pro-Opiomelanocortin -- metabolism, Rats, Wistar, Risk Factors, adipose tissue, hypothalamus, insulin, leptin, nutrition, undernutrition, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/231875/3/PMC4521053.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/231875/5/doi_215502.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/231875
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المؤلفون: Rouger, Laurie, Denis, G Raphaël, Luangsay, Souphalone, Parmentier, Marc

المصدر: Journal of Endocrinology, 219 (3

مصطلحات الفهرس: Sciences exactes et naturelles, Adipogenesis, Adipose Tissue, White -- enzymology -- metabolism -- pathology, Adiposity, Aging, Animals, Biological Markers -- metabolism, Chemotactic Factors -- genetics -- metabolism, Diet, High-Fat -- adverse effects, Female, Glycerolphosphate Dehydrogenase -- genetics -- metabolism, Intercellular Signaling Peptides and Proteins -- genetics -- metabolism, Isoenzymes -- metabolism, Lipogenesis, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity -- etiology -- metabolism -- pathology, Overweight -- etiology -- metabolism -- pathology, Receptors, G-Protein-Coupled -- genetics -- metabolism, Sex Characteristics, Signal Transduction, Weight Gain, Adipokines, G-protein-coupled receptor, Inflammation, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/157496/3/doi_142558.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/157496
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL