المؤلفون: Nasr SM; Department of Biochemistry and Molecular Biology, Theodor Bilharz Research Institute, Giza 12411, Egypt; School of Biotechnology, Badr University in Cairo, Badr City, Cairo 11829, Egypt. Electronic address: s.nasr@tbri.gov.eg., Hassan M; Department of Immunology, Theodor Bilharz Research Institute, Giza 12411, Egypt. Electronic address: marwahassan_777@yahoo.com., Abou-Shousha T; Department of Pathology, Theodor Bilharz Research Institute, Giza 12411, Egypt. Electronic address: t.aboushousha@tbri.gov.eg., Elhusseny Y; School of Medicine, NewGiza University, Giza 12585, Egypt. Electronic address: dryasmina@hotmail.com., Elzallat M; Department of Immunology, Theodor Bilharz Research Institute, Giza 12411, Egypt. Electronic address: zallatzallat@gmail.com.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117190. Date of Electronic Publication: 2024 Jul 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Liver Regeneration*/drug effects , Liver Cirrhosis*/chemically induced , Liver Cirrhosis*/drug therapy , Liver Cirrhosis*/pathology , Liver Cirrhosis*/metabolism , Diethylnitrosamine*/toxicity , Placenta*/drug effects , Placenta*/metabolism, Animals ; Female ; Mice ; Pregnancy ; Male ; Liver/drug effects ; Liver/pathology ; Liver/metabolism ; Transforming Growth Factor beta/metabolism ; Disease Models, Animal ; NF-kappa B/metabolism ; Actins/metabolism

المؤلفون: Tamim YM; Clinical Pharmacology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Nagy AA; Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Abdellah AM; Pathophysiology Department, Grand Canyon University, Phoenix, Arizona, USA., Osman AH; Pathology Department, Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt., Ismail AFM; Drug Radiation Research Department, Biotechnology Division, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.

المصدر: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2024 Aug; Vol. 38 (4), pp. 742-757. Date of Electronic Publication: 2024 Feb 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Science Country of Publication: England NLM ID: 8710411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-8206 (Electronic) Linking ISSN: 07673981 NLM ISO Abbreviation: Fundam Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Diethylnitrosamine*/toxicity , Propranolol*/pharmacology , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/chemically induced, Animals ; Male ; Rats ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/drug therapy ; Liver Neoplasms, Experimental/pathology ; Antineoplastic Agents/pharmacology ; Liver Neoplasms/drug therapy ; Liver Neoplasms/chemically induced ; Liver Neoplasms/pathology ; Disease Models, Animal ; Adrenergic beta-Antagonists/pharmacology

المؤلفون: Vanli S; Ministry of Agriculture and Forestry, Ilgin District Directorate of Agriculture and Forestry, Konya, Turkey., Kurtoglu F; Department of Biochemistry, Faculty of Veterinary Sciences, Selcuk University, Konya, Turkey., Alan BS; Department of Biochemistry, Faculty of Veterinary Sciences, Selcuk University, Konya, Turkey., Akcakavak G; Department of Pathology, Faculty of Veterinary Sciences, Yozgat Bozok University, Yozgat, Turkey., Ozdemir O; Department of Pathology, Faculty of Veterinary Sciences, Selcuk University, Konya, Turkey.

المصدر: Toxicology mechanisms and methods [Toxicol Mech Methods] 2024 Sep; Vol. 34 (7), pp. 750-760. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101134521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6524 (Electronic) Linking ISSN: 15376516 NLM ISO Abbreviation: Toxicol Mech Methods Subsets: MEDLINE

مواضيع طبية MeSH: Sorafenib*/pharmacology , Apoptosis*/drug effects , Carcinoma, Hepatocellular*/chemically induced , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Diethylnitrosamine*/toxicity, Animals ; Male ; Plant Extracts/pharmacology ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/pathology ; Liver Neoplasms, Experimental/drug therapy ; Liver Neoplasms, Experimental/metabolism ; Liver Neoplasms/chemically induced ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Liver Neoplasms/metabolism ; Rats ; Liver/drug effects ; Liver/pathology ; Liver/metabolism ; Antineoplastic Agents/pharmacology ; Nitrosamines/toxicity

المؤلفون: Janmeda P; Department of Bioscience and Biotechnology, Banasthali Vidyapith, Tonk, Rajasthan, India., Jain D; Department of Bioscience and Biotechnology, Banasthali Vidyapith, Tonk, Rajasthan, India., Chaudhary P; Department of Bioscience and Biotechnology, Banasthali Vidyapith, Tonk, Rajasthan, India., Meena M; Laboratory of Phytopathology and Microbial Biotechnology, Department of Botany, Mohanlal Sukhadia University, Udaipur, Rajasthan, India., Singh D; Department of Chemistry, Mohanlal Sukhadia University, Udaipur, Rajasthan, India.

المصدر: Journal of applied toxicology : JAT [J Appl Toxicol] 2024 Aug; Vol. 44 (8), pp. 1108-1128. Date of Electronic Publication: 2024 Jan 11.

نوع المنشور: Journal Article; Systematic Review; Review

بيانات الدورية: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1263 (Electronic) Linking ISSN: 0260437X NLM ISO Abbreviation: J Appl Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Diethylnitrosamine*/toxicity , Carcinogens*/toxicity, Humans ; Risk Assessment ; Animals ; Oxidative Stress/drug effects ; Neoplasms/chemically induced

المؤلفون: Guo J; Department of Basic Medical Sciences, Capital Medical University, Beijing 100069, PR China., Zhang X; Department of Gastroenterology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100071, PR China., Xu Y; Department of Gastroenterology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100071, PR China., Li B; Department of Clinical Laboratory, The Fifth Medical Centre of Chinese PLA General Hospital, Beijing 100071, PR China., Min M; Department of Gastroenterology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100071, PR China. Electronic address: minmin823@sina.com.

المصدر: Toxicology letters [Toxicol Lett] 2024 Jul; Vol. 398, pp. 49-54. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol Lett Subsets: MEDLINE

مواضيع طبية MeSH: Diethylnitrosamine*/toxicity , Dextran Sulfate*/toxicity , Colitis*/chemically induced , Colitis*/pathology , Mice, Knockout* , Chemical and Drug Induced Liver Injury*/pathology , Chemical and Drug Induced Liver Injury*/etiology , Chemical and Drug Induced Liver Injury*/genetics, Animals ; Mice, Inbred C57BL ; Male ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Mice ; Inflammation/chemically induced ; Inflammation/pathology ; Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/deficiency ; Liver/pathology ; Liver/drug effects ; Liver/metabolism ; Disease Models, Animal ; Colon/pathology ; Colon/drug effects

المؤلفون: Haewphet T; Department of Physiology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: thaiyawath64@nu.ac.th., Parhira S; Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence for Environmental Health and Toxicology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: supawadeep@nu.ac.th., Chaisupasakul P; Department of Physiology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: pattarapornc63@nu.ac.th., Wangteeraprasert A; Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: apirathw@nu.ac.th., Phoungpetchara I; Department of Anatomy, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence in Medical Biotechnology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: ittiponp@nu.ac.th., Pekthong D; Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence for Environmental Health and Toxicology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, 65000, Thailand; Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: dumrongsakp@nu.ac.th., Kaewkong W; Department of Biochemistry, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence in Medical Biotechnology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: worasakk@nu.ac.th., Jiang ZH; State Key Laboratory of Quality Research in Chinese Medicine, Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, China. Electronic address: zhjiang@must.edu.mo., Bai LP; State Key Laboratory of Quality Research in Chinese Medicine, Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, China. Electronic address: lpbai@must.edu.mo., Somran J; Department of Pathology, Faculty of Medicine, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: julintorns@nu.ac.th., Srisawang P; Department of Physiology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand; Center of Excellence in Medical Biotechnology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand. Electronic address: piyarats@nu.ac.th.

المصدر: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Nov 15; Vol. 334, pp. 118516. Date of Electronic Publication: 2024 Jul 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Plant Extracts*/pharmacology , Plant Extracts*/therapeutic use , Plant Bark*/chemistry , Diethylnitrosamine*/toxicity , Methylene Chloride*/chemistry , Insulin*/blood , Calotropis*/chemistry , Diabetes Mellitus, Experimental*/drug therapy, Animals ; Male ; Rats ; Liver Neoplasms/prevention & control ; Liver Neoplasms/drug therapy ; Liver Neoplasms/chemically induced ; Liver Neoplasms/pathology ; Diabetes Mellitus, Type 2/drug therapy ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/isolation & purification ; Carcinoma, Hepatocellular/chemically induced ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/prevention & control ; Liver/drug effects ; Liver/pathology ; Liver/metabolism ; Blood Glucose/drug effects ; Plant Stems/chemistry ; Liver Neoplasms, Experimental/prevention & control ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/drug therapy ; Liver Neoplasms, Experimental/pathology

المؤلفون: Ligi S; School of Natural Sciences, Laurentian University, Sudbury, Canada; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Canada., Ali A; School of Natural Sciences, Laurentian University, Sudbury, Canada; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Canada., Yang G; School of Natural Sciences, Laurentian University, Sudbury, Canada; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Canada. Electronic address: gyang2@laurentian.ca.

المصدر: Nitric oxide : biology and chemistry [Nitric Oxide] 2024 Oct 01; Vol. 151, pp. 1-9. Date of Electronic Publication: 2024 Aug 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9709307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8611 (Electronic) Linking ISSN: 10898603 NLM ISO Abbreviation: Nitric Oxide Subsets: MEDLINE

مواضيع طبية MeSH: Cystathionine gamma-Lyase*/metabolism , Cystathionine gamma-Lyase*/deficiency , Cystathionine gamma-Lyase*/genetics , Mice, Knockout* , Diethylnitrosamine*, Animals ; Male ; Mice ; Liver/metabolism ; Liver/pathology ; Oxidative Stress ; Hydrogen Sulfide/metabolism ; Chemical and Drug Induced Liver Injury/metabolism ; Mice, Inbred C57BL

المؤلفون: Cai H; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. Electronic address: 15258374598@163.com., Zhang Y; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, China. Electronic address: 1135752376@qq.com., Wang J; Department of Pathology, Affiliated Hospital of Jiaxing University, The First Hospital of Jiaxing, Jiaxing, Zhejiang, China. Electronic address: 11018140@zju.edu.cn., Deng Y; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China. Electronic address: 1481563523@qq.com., Liu J; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China. Electronic address: 2577737551@qq.com., Wu Z; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China; Department of Infectious Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, China. Electronic address: 18270632702@163.com., Cao D; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China. Electronic address: 2116823122@qq.com., Song Z; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China; Department of Infectious Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, China. Electronic address: songzhiying717@163.com., Wang L; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China. Electronic address: 2843155847@qq.com., Xie B; Medical College of Jiaxing University, Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, China; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. Electronic address: xiebaogang49@zjxu.edu.cn.

المصدر: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Nov 15; Vol. 334, pp. 118569. Date of Electronic Publication: 2024 Jul 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Diethylnitrosamine*/toxicity , Uric Acid*/blood , Carcinoma, Hepatocellular*/chemically induced , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/pathology , Reactive Oxygen Species*/metabolism, Animals ; Male ; Rats ; Liver Neoplasms/chemically induced ; Liver Neoplasms/drug therapy ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Rats, Sprague-Dawley ; Lactones/pharmacology ; Cell Line, Tumor ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/drug therapy ; Liver Neoplasms, Experimental/metabolism ; Liver Neoplasms, Experimental/pathology ; Signal Transduction/drug effects ; Drugs, Chinese Herbal/pharmacology ; Disaccharides/pharmacology

المؤلفون: Deeb AA; Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan., Hailat M; Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan., Aldoqum HM; Automated Chemical Laboratories, Royal Scientific Society, Amman 11941, Jordan., Abuothman M; Automated Chemical Laboratories, Royal Scientific Society, Amman 11941, Jordan., Abuyaman O; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa 13133, Jordan., Abu Dayyih W; Department of Pharmacy, Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.

المصدر: Journal of chromatographic science [J Chromatogr Sci] 2024 Apr 23; Vol. 62 (4), pp. 372-379.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited Medium: Internet ISSN: 1945-239X (Electronic) Linking ISSN: 00219665 NLM ISO Abbreviation: J Chromatogr Sci Subsets: MEDLINE

مواضيع طبية MeSH: Irbesartan*/analysis , Irbesartan*/chemistry , Tandem Mass Spectrometry*/methods , Metformin*/analysis , Metformin*/chemistry , Dimethylnitrosamine*/analysis , Dimethylnitrosamine*/chemistry , Drug Contamination* , Limit of Detection* , Tablets* , Tetrazoles*/analysis , Tetrazoles*/chemistry , Diethylnitrosamine*/analysis , Imidazoles*/analysis , Imidazoles*/chemistry, Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Linear Models

المؤلفون: Lan X; School of Public Health, Sun Yat-Sen University, No. 74 Zhongshan Road 2, Guangzhou, 510080, China; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China., Huang H; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China., Liu J; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China., Zhao J; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China., Li G; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China., Zuo M; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China., Xing X; School of Public Health, Sun Yat-Sen University, No. 74 Zhongshan Road 2, Guangzhou, 510080, China. Electronic address: xingxm3@mail.sysu.edu.cn., Ren X; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China. Electronic address: slim54@126.com.

المصدر: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2024 Apr; Vol. 186, pp. 114519. Date of Electronic Publication: 2024 Feb 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Diethylnitrosamine*/toxicity , Non-alcoholic Fatty Liver Disease*/chemically induced , Non-alcoholic Fatty Liver Disease*/metabolism, Rats ; Animals ; Triglycerides/metabolism ; Lipoproteins, VLDL/metabolism ; Rats, Sprague-Dawley ; Liver/metabolism ; Lipid Metabolism ; Lipoproteins, LDL/metabolism ; Diet, High-Fat