المؤلفون: Marie‐Joe Dib, Michael G. Levin, Lei Zhao, Ahmed Diab, Zhaoqing Wang, Christina Ebert, Oday Salman, Joe David Azzo, Sushrima Gan, Payman Zamani, Jordana B. Cohen, Dipender Gill, Stephen Burgess, Loukas Zagkos, Vanessa van Empel, A. Mark Richards, Rob Doughty, Ernst R. Rietzschel, Karl Kammerhoff, Erika Kvikstad, Joseph Maranville, Peter Schafer, Dietmar A. Seiffert, Francisco Ramirez‐Valle, David A. Gordon, Ching‐Pin Chang, Ali Javaheri, Douglas L. Mann, Thomas P. Cappola, Julio A. Chirinos

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 5 (2024)

مصطلحات موضوعية: heart failure, HFrEF, Mendelian randomization, proteomics, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/5a885cf45ed64ca0bb38fb1fc18ac373

المؤلفون: Jing Yang, Claudio Mapelli, Zhaoqing Wang, Chi Shing Sum, Ji Hua, R. Michael Lawrence, Yan Ni, Dietmar A. Seiffert

المصدر: Platelets, Vol 33, Iss 7, Pp 979-986 (2022)

مصطلحات موضوعية: antiplatelet assay, platelet, protease-activated receptor 4, thrombin, thrombosis, Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0953-7104; https://doaj.org/toc/1369-1635

URL الوصول: https://doaj.org/article/da63be13adb74a87bc2112cc0441e456

المؤلفون: Joseph M. Luettgen, Danshi Li, Vidya Perera, Dietmar A. Seiffert, Michael Cerra, Mary M. DeSouza, Zhaoqing Wang

المصدر: Clinical and Translational Science, Vol 15, Iss 2, Pp 330-342 (2022)

مصطلحات موضوعية: Adult, Male, Administration, Oral, RM1-950, Pharmacology, Placebo, General Biochemistry, Genetics and Molecular Biology, Factor XIa, Food-Drug Interactions, Pharmacokinetics, Double-Blind Method, Medicine, Humans, Dosing, General Pharmacology, Toxicology and Pharmaceutics, Adverse effect, medicine.diagnostic_test, Dose-Response Relationship, Drug, business.industry, General Neuroscience, General Medicine, Middle Aged, Triazoles, Bioavailability, Pyrimidines, Tolerability, Pharmacodynamics, Female, Partial Thromboplastin Time, Therapeutics. Pharmacology, Public aspects of medicine, RA1-1270, business, Partial thromboplastin time

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f046f769db062156f33f36d0c9a946ee
https://doaj.org/article/4b838c4b10764abf9f031700c2e76a7e

المؤلفون: Ali Javaheri, Ahmed Diab, Lei Zhao, Chenao Qian, Jordana B. Cohen, Payman Zamani, Anupam Kumar, Zhaoqing Wang, Christina Ebert, Joseph Maranville, Erika Kvikstad, Michael Basso, Vanessa van Empel, A. Mark Richards, Robert N. Doughty, Ernst Rietzschel, Karl Kammerhoff, Joseph Gogain, Peter Schafer, Dietmar A. Seiffert, David A. Gordon, Francisco Ramirez-Valle, Douglas L. Mann, Thomas P. Cappola, Julio A. Chirinos

المساهمون: Cardiologie, MUMC+: MA Med Staf Spec Cardiologie (9), RS: Carim - H02 Cardiomyopathy

المصدر: Circulation-Heart Failure, 15(9):e009693, 827-837. LIPPINCOTT WILLIAMS & WILKINS

مصطلحات موضوعية: Proteomics, Caspases/pharmacology, Proteome, Insulins, Phospholipid Transfer Proteins/pharmacology, Spironolactone, Apelin/pharmacology, Mineralocorticoid Receptor Antagonists/therapeutic use, Humans, Phospholipid Transfer Proteins, Mineralocorticoid Receptor Antagonists, Liver X Receptors, Heart Failure, Biological Products, Biological Products/pharmacology, Stroke Volume, Spironolactone/adverse effects, Caspase, Insulins/therapeutic use, Treatment Outcome, Stroke Volume/physiology, Caspases, Apelin, Americas, Glycoprotein, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980f9dd5334c696b715fca8601c1ecf6
https://cris.maastrichtuniversity.nl/en/publications/62321d15-760a-4f2d-8899-90d734b938b7

المؤلفون: John G.F. Cleland, Arend Mosterd, John R. Teerlink, Marco Metra, Peter S. Pang, Naoki Sato, Dietmar A. Seiffert, Ninian N. Lang, June Ye, Héctor Bueno, Felipe Martinez, Jan Belohlavek, Christopher M. O'Connor, Maria Borentain, Adriaan A. Voors, G. Michael Felker, Robert T. Cole, Paul D. Kessler, Piotr Ponikowski, Michael Böhm, Gerasimos Filippatos, Mary M. DeSouza, Justin A. Ezekowitz, Alex Mebazaa, John J.V. McMurray

المصدر: JACC: Heart Failure. 9:146-157

مصطلحات موضوعية: Inotrope, medicine.drug_class, business.industry, 030204 cardiovascular system & hematology, medicine.disease, Placebo, Discontinuation, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Anesthesia, Relative risk, Heart failure, Clinical endpoint, Natriuretic peptide, medicine, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b6da5be063a302f95d8049cbac21c366
https://doi.org/10.1016/j.jchf.2020.10.012

المؤلفون: Arunachalam Arumugam, Dietmar A. Seiffert, Arvind Mathur, Joanna J. Zheng, Ruth R. Wexler, Jeon Yoon T, Premsai Rai Neithnadka, Earl J. Crain, Paul J. Gilligan, Patrick Y.S. Lam, Yiming Wu, Mahammed Kaspady, Pancras C. Wong, Tianan Fang, Silvi A. Chacko, William R. Ewing, Pabbisetty Kumar Balashanmuga, Zhen Lou, Steven Sheriff, Joseph M. Luettgen, Joseph E. Myers, Wu Yang, Karen A. Rossi, Richard Rampulla, James R. Corte, Amy Lai, Charles G. Clark, Jeffrey M. Bozarth, Yufeng Wang, Sivashankaran Raju

المصدر: Journal of Medicinal Chemistry. 63:7226-7242

مصطلحات موضوعية: Models, Molecular, Proteases, Macrocyclic Compounds, Drug Evaluation, Preclinical, Administration, Oral, Biological Availability, Pharmacology, Crystallography, X-Ray, 01 natural sciences, Factor XIa, Serine, Structure-Activity Relationship, 03 medical and health sciences, Dogs, Fibrinolytic Agents, Pharmacokinetics, In vivo, Drug Discovery, Antithrombotic, Animals, Humans, Structure–activity relationship, 030304 developmental biology, 0303 health sciences, Chemistry, 0104 chemical sciences, Bioavailability, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Rabbits, Hydrophobic and Hydrophilic Interactions, Linker

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ab508367fcb2f182343eb9240eeb1b
https://doi.org/10.1021/acs.jmedchem.0c00464

المؤلفون: Julio A. Chirinos, Zhaoqing Wang, Stuart B. Prenner, David A. Gordon, Payman Zamani, Zhuyin Li, Sarah J. Schrauben, Jordana B. Cohen, Dietmar A. Seiffert, Priyanka Bhattacharya, Thomas P. Cappola, Michael Basso, Lei Zhao, Mary Ellen Cvijic, Melissa Yarde, Bruce D. Car, Kenneth B. Margulies, Diana A. Chirinos

المصدر: JACC: Heart Failure. 8:172-184

مصطلحات موضوعية: Cardiac function curve, medicine.medical_specialty, business.industry, Atrial fibrillation, 030204 cardiovascular system & hematology, medicine.disease, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Heart failure, Internal medicine, medicine, Spironolactone, Clinical endpoint, Left atrial enlargement, Cardiology, Arterial stiffness, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, Heart failure with preserved ejection fraction, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8429d68b2f8aefa63f12b27377888e80
https://doi.org/10.1016/j.jchf.2019.09.009

المؤلفون: Michael Basso, David A. Gordon, Julio A. Chirinos, Thomas P. Cappola, Zhaoqing Wang, Mary Ellen Cvijic, Dietmar A. Seiffert, Payman Zamani, Priyanka Bhattacharya, Melissa Yarde, Bruce D. Car, Stuart B. Prenner, Kenneth B. Margulies, Jason H. Moore, Zhuyin Li, Thomas E. Spires, Alena Orlenko, Anupam Kumar, Lei Zhao

المصدر: Journal of the American College of Cardiology. 75:1281-1295

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Ejection fraction, business.industry, medicine.drug_class, Hazard ratio, 030204 cardiovascular system & hematology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Osteoprotegerin, Fibrosis, Internal medicine, Heart failure, Natriuretic peptide, Medicine, Biomarker (medicine), 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, Heart failure with preserved ejection fraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::50844f066fc02776c67b16d6c5365949
https://doi.org/10.1016/j.jacc.2019.12.069

المؤلفون: Mary Ellen Cvijic, Jeremy A. Mazurek, Melissa Yarde, Michael Basso, Julio A. Chirinos, Zhaoqing Wang, Stuart B. Prenner, Dietmar A. Seiffert, Zhuyin Li, Payman Zamani, Priyanka Bhattacharya, David A. Gordon, Thomas E. Spires, Lei Zhao, Anupam Kumar

المصدر: The American Journal of Cardiology. 125:575-582

مصطلحات موضوعية: Male, medicine.medical_specialty, Serum albumin, Spironolactone, 030204 cardiovascular system & hematology, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Double-Blind Method, Risk Factors, Internal medicine, medicine, Clinical endpoint, Humans, 030212 general & internal medicine, Serum Albumin, Aged, Mineralocorticoid Receptor Antagonists, Heart Failure, Framingham Risk Score, biology, business.industry, Albumin, Stroke Volume, Middle Aged, Prognosis, medicine.disease, Arterial stiffness, biology.protein, Albuminuria, Cardiology, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, Heart failure with preserved ejection fraction, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c93cc6d728396c34f30e487beeaeeb
https://doi.org/10.1016/j.amjcard.2019.11.006

المؤلفون: Zhu Chen, Bin Luo, Tian-Quan Cai, Anil Thankappan, Yiming Xu, Weizhen Wu, Jillian DiMuzio, Traci Lifsted, Marty DiPietro, Jyoti Disa, Bruce Ng, Karen Leander, Seth Clark, Lizbeth Hoos, Yuchen Zhou, Nina Jochnowitz, Christine Jachec, Peter Szczerba, Marian E Gindy, Walter Strapps, Laura Sepp-Lorenzino, Dietmar A Seiffert, Laura Lubbers, Marija Tadin-Strapps

المصدر: Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)

مصطلحات موضوعية: coagulation, Factor X, lipid nanoparticle, plasma kallikrein, siRNA, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253116300087; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/da51b10ff9c64e0ebedcb655dbab5e3c