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    المساهمون: Drug Design, Medicinal Chemistry and Bioanalysis (MCB)

    المصدر: ChemMedChem, 10(11), 1837-1845. WILEY-V C H VERLAG GMBH
    ChemMedChem
    info:cnr-pdr/source/autori:Wu, S.a,b, Huang, J.a, Gazzarrini, S.c, He, S.a, Chen, L.a, Li, J.a, Xing, L.d, Li, C.e, Chen, L.e, Neochoritis, C.G.f, Liao, G.P.f, Zhou, H.a, Dömling, A.f, Moroni, A.c, Wang, W./titolo:Isocyanides as influenza A virus subtype H5N1 wild-type M2 channel inhibitors/doi:10.1002%2Fcmdc.201500318/rivista:ChemMedChem (Print)/anno:2015/pagina_da:1837/pagina_a:1845/intervallo_pagine:1837–1845/volume:10

    مصطلحات موضوعية: antivirus agent, virus strain, 5 (tert butyl) 2 isocyano 1, isocyanide, synthesis, matrix protein, IC50, Pharmacology, medicine.disease_cause, proton nuclear magnetic resonance, Biochemistry, virus inhibition, Madin Darby Canine Kidney Cells, n [4 (tert butyl)cyclohexyl]formamide, dose response, Drug Discovery, Influenza A Virus, animal, 3 isocyanoadamantan 1 ol, General Pharmacology, Toxicology and Pharmaceutics, influenza A, Cytotoxicity, 1 (1 isocyanoethyl)adamantine, development and aging, 6 trimethylbicyclo[3.1.1]heptan 3 yl)formamide, MDCK cell line, unclassified drug, n (adamantan 1 yl)formamide, EC50, microbial sensitivity test, Influenza A virus (H1N1), 2 isocyanoadamantane, priority journal, 1 isocyanoadamantane, Influenza A virus (H5N1), dog, antiviral activity, Molecular Medicine, H5N1 Subtype, Drug, 6 trimethylbicyclo[3.1.1]heptane, medicine.drug, growth, animal experiment, Microbial Sensitivity Tests, Biology, 4 trimethylpentane, chemistry, Antiviral Agents, Article, Virus, drug clearance, Dose-Response Relationship, Viral Matrix Proteins, Structure-Activity Relationship, 3 dimethylbenzene, Dogs, n ( 2, site directed mutagenesis, medicine, Animals, Structure–activity relationship, controlled study, drug binding site, Channel blocker, M2 protein, mouse, antagonists and inhibitors, structure activity relation, amantadine, cyanide, nonhuman, Cyanides, Viral matrix protein, Dose-Response Relationship, Drug, Influenza A Virus, H5N1 Subtype, microbiology, Organic Chemistry, Amantadine, Wild type, molecular docking, carbon nuclear magnetic resonance, molecular dynamics, Influenza A virus subtype H5N1, 3 isocyano 2, drug effects, 1 (tert butyl) 4 isocyanocyclohexane, 2 isocyano 2, drug synthesis, Influenza virus, metabolism, virus attachment

    وصف الملف: application/pdf

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    المساهمون: LABORATOIRE DE THERMIQUE ENERGETIQUE ET PROCEDES (EA1932) (LATEP), Université de Pau et des Pays de l'Adour (UPPA), Planta Piloto de Ingeniería Química [Bahía Blanca] (PLAPIQUI), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Universidad Nacional del Sur [Argentina] (UNS)

    المصدر: Journal of Chemical and Engineering Data
    Journal of Chemical and Engineering Data, American Chemical Society, 2013, 58 (3), pp.758-763. ⟨10.1021/je301282p⟩

    وصف الملف: application/pdf

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