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المؤلفون: N. S. Petrov, Mikhail Baryshev, Boris Popov, V. A. Ryabov
المصدر: Genes and Diseases, Vol 9, Iss 1, Pp 165-175 (2022)
Genes & Diseasesمصطلحات موضوعية: Medicine (General), MSCs, mesenchymal stem cells, AD, adipogenic differentiation, MSCs, Cell fate determination, QH426-470, Biochemistry, 03 medical and health sciences, R5-920, pRb, RB product, Full Length Article, DNMT1, DNA methyltransferase 1, Genetics, Epigenetics, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, RB, retinoblastoma susceptibility gene, Chemistry, 030302 biochemistry & molecular biology, Mesenchymal stem cell, DNA methyltransferase 1, Cell Biology, Transfection, Methylation, Cell biology, Adipogenesis, Cell culture, DNA methylation, Adipogenic differentiation, Mesenchymal stem cells, Retinoblastoma susceptibility gene, RB
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المؤلفون: Shuya Luo, Lichuan Bai, Guan Wang, Sitong Liu, Hui Wang, Qinghuan Xiao, Ke Ma, Tianyu Wang, Kuan Gao, Hongyue Liang, Mei Liu
المصدر: Journal of Advanced Research
Journal of Advanced Research, Vol 29, Iss, Pp 23-32 (2021)مصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Angiogenesis, Endothelial cells, CCK-8, Cell Counting Kit-8, 0302 clinical medicine, Cell Movement, 5-aza, 5-Aza-2′-deoxycytidine, Endothelial dysfunction, Aorta, ANOVA, analysis of variance, Tube formation, lcsh:R5-920, Multidisciplinary, Neovascularization, Pathologic, Chemistry, Cell migration, Transfection, Cell biology, Endothelial stem cell, Cholesterol, Blood-Brain Barrier, 030220 oncology & carcinogenesis, Hypertension, Medicine, lcsh:Medicine (General), HEPES, N-2-hydroxyethil-piperazine-N'-2-ethanesulfonic acid, DMEM, Dulbecco’s Modified Eagle Medium, DNA (Cytosine-5-)-Methyltransferase 1, HAECs, human aortic endothelial cells, PVDF, polyvinylidene fluoride, RIPA, radio immunoprecipitation assay, 03 medical and health sciences, EGTA, ethylene glycol-bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid, ROS, reactive oxygen species, Downregulation and upregulation, FBS, fetal bovine serum, Chloride Channels, medicine, DNMT1, DNA methyltransferase 1, NMDG, N-methyl-D-glucamine, Humans, lcsh:Science (General), shRNAs, short hairpin RNAs, Anoctamin-1, Cell Proliferation, MβCD, methyl-β cyclodextrin, TMEM16A, SE, standard error, HEK 293 cells, medicine.disease, HEK293 Cells, 030104 developmental biology, Calcium, CaCCs, Ca2+-activated Cl− currents, lcsh:Q1-390
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المؤلفون: Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: TIM-3, T cell immunoglobulin and mucin domain 3, H3K27me3, tri-methylation of lysine 27 on histone H3, MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, Review, TAA, tumor-associated antigen, DC, dendritic cell, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, LAG-3, lymphocyte activation gene-3, CTLA-4, cytotoxic T lymphocyte antigen 4, Medicine, BETi, bromodomain and extra-terminal motif inhibitors, General Pharmacology, Toxicology and Pharmaceutics, FOXP3, forkhead box P3, HDACi, histone deacetylase inhibitor, Cancer, 0303 health sciences, ACE1, angiotensin converting enzyme, CLL, chronic lymphocytic leukemia, biology, IDO, indoleamine 2,3-dioxygenase, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Tregs, regulatory T cells, PD-L1/PD-1 blockade, CCL22 (MDC), macrophage-derived chemokine, Immunotherapy, TET2, ten-eleven translocation 2, CTLs, cytotoxic T lymphocytes, FDA, U. S. Food and Drug Administration, PD-L1, programmed cell death ligand 1, T cell, CTA, cancer testis antigen, Immune cycle, TIL, tumor infiltrating lymphocytes, Epigenetic regulation, OS, overall survival, 03 medical and health sciences, Immune system, Antigen, PD-L1, TH-1, T helper type 1, DNMT1, DNA methyltransferase 1, MHC, major histocompatibility complex, CX3CL1, C-X3-C motif chemokine ligand 1, IFN-γ, interferon-gamma, 030304 developmental biology, business.industry, lcsh:RM1-950, biochemical phenomena, metabolism, and nutrition, medicine.disease, CXCL, CXC chemokine ligand, Blockade, lcsh:Therapeutics. Pharmacology, APC, antigen-presenting cell, UHRF1, ubiquitin-like PHD and RING finger domain-containing 1, 5-AzaC, 5-azacitidine, ACP1, human red cell acid phosphatase, biology.protein, Cancer research, bacteria, DNMTi, DNA methyltransferase inhibitors, PD-1, programmed cell death 1, business, PRC2, polycomb repressive complex 2
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المؤلفون: Geir Bjørklund, Athanasia K. Georgiopoulou, Spyros P. Perlepes, Massimiliano Francesco Peana, Christos T. Chasapis
المصدر: Journal of Inorganic Biochemistry
مصطلحات موضوعية: viruses, PD, Parkinson's Diseases, VPS11, vacuolar protein sorting-associated protein 11, HNSCC, head and neck squamous cell carcinoma, medicine.disease_cause, 01 natural sciences, Biochemistry, CSNK2B, casein kinase II subunit beta, Pandemic, HT, hypertension, Coronavirus, Genetics, Chemistry, virus diseases, Metal homeostasis, COVID-19, corona virus disease 2019, CPS1, carbamoyl-phosphate synthase 1, SIRT5, sirtuin-5, AMD, age macular degeneration, Proteome, Host-Pathogen Interactions, Coronavirus disease 2019 (COVID-19), PPI, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), CNS, central nervous system, 010402 general chemistry, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Article, Virus, PPI, protein-protein interaction, Inorganic Chemistry, Viral Proteins, Metalloproteins, DNMT1, DNA methyltransferase 1, medicine, Humans, Cb5, cytochrome b5, AD, Alzheimer's Disease, Human proteins, 010405 organic chemistry, SARS-CoV-2, SARS-CoV-2 orf8, COVID-19, KRCC, kidney renal clear cell carcinoma, Metalloproteome, 0104 chemical sciences, ZNF318, zinc finger protein 318, Carrier protein, Nervous System Diseases, Carrier Proteins, ITGB1, integrin beta-1
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المؤلفون: Yiting Guan, Xiaoke Huang, Wei Tao, Li Huang, Qianqian Gao, Chao Zhang, Lijun Zhang, Le Zong, Ran Wei, Guoliang Lyu, Xuebin Zhang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: DNA (Cytosine-5-)-Methyltransferase 1, DMEM, Dulbecco's modified Eagle medium, Transcription, Genetic, PHF6, rDNA transcription, MeDIP-seq, methylated DNA immunoprecipitation sequencing, DNA, Ribosomal, Biochemistry, DNA methyltransferase, PHD, plant homeodomain, Histones, FBS, fetal bovine serum, Transcription (biology), Gene expression, DNMT1, DNA methyltransferase 1, Humans, ChIP-qPCR, chromatin immunoprecipitation assays followed by real-time quantitative PCR, RT-qPCR, real-time quantitative reverse transcription PCR, Molecular Biology, biology, DNMT1, Histone-Lysine N-Methyltransferase, Cell Biology, Methylation, DNA Methylation, PHF6, PHD finger protein 6, Cell biology, Repressor Proteins, gene body methylation, rRNA, Ribosomal RNA, HEK293 Cells, Histone, UBF, upstream binding factor, Histone methyltransferase, DNA methylation, biology.protein, H4K20me3, IGS, intergenic spacer, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73ca5dbe5a7f2b583dccf861fe99871
https://doi.org/10.1016/j.jbc.2021.101195 -
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المؤلفون: Isamu Kameshita, Yasunori Sugiyama
المصدر: Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 40-45 (2017)مصطلحات موضوعية: 0301 basic medicine, CNBr, cyanogen bromide, Monoclonal antibody, Proteomics, CaMK, Ca2+/calmodulin-dependent protein kinase, Biophysics, Kinomics, 2D-PAGE, two-dimensional polyacrylamide gel electrophoresis, Computational biology, Review Article, CDKL5, cyclin-dependent kinase-like 5, Biochemistry, Protein kinase, lcsh:Biochemistry, 03 medical and health sciences, Protein phosphorylation, NCK1, lcsh:QD415-436, MeCP2, methylated-CpG-binding protein 2, Protein kinase A, lcsh:QH301-705.5, MAPK14, 030102 biochemistry & molecular biology, biology, Kinase, GRB10, DCLK, double-cortin like protein kinase, IPG, immobilized pH gradient, IEF, isoelectric focusing, 030104 developmental biology, lcsh:Biology (General), CDC37, FAK, focal adhesion kinase, Dnmt1, DNA methyltransferase 1, biology.protein, MAPK, mitogen-activated protein kinase
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المؤلفون: Fielden, J, Ruggiano, A, Popović, M, Ramadan, K
المصدر: DNA Repair
مصطلحات موضوعية: WLM, Wss1p-like metalloproteases, PTM, post-translational modification, DNA Repair, ERCC1, excision repair cross-complementing gene 1, DNA-protein crosslinks, PARP, poly (ADP-ribose) Polymerase, SUMO, small ubiquitin-like modifier, DNA Adducts, HER2, human epidermal growth factor receptor 2, SPRTN protease, ACRC, acidic repeat containing, Cancer, SIM, SUMO-interacting motif, ss/ds DNA, single-stranded/double-stranded DNA, PIAS, protein inhibitor of activated STAT protein, MEFs, mouse embryonic fibroblasts, Top1/2-cc, topoisomerase 1/2 cleavage complex, Eukaryota, MRN complex, Mre11-Rad50-Nbs1 complex, DNA-Binding Proteins, Cross-Linking Reagents, DPCP, DNA-protein crosslink proteolysis, FA, formaldehyde, CPT, camptothecin, Post-translational modification, Saccharomyces cerevisiae Proteins, PCNA, proliferating cell nuclear antigen, UBC9, ubiquitin carrier protein 9, GCNA, germ cell nuclear antigen, Saccharomyces cerevisiae, Article, 5-aza-dC, 5-aza-2′-deoxycytidine, SHP, Src homology 2-containing Phosphatase, C. elegans, Caenorhabditis elegans, RJALS, Ruijs–Aalfs syndrome, UBZ, ubiquitin-binding zinc finger, NER, nucleotide excision repair, NSCLC, non-small cell lung cancer, STUbL, SUMO-targeted ubiquitin ligases, Genome stability, DNMT1, DNA methyltransferase 1, DPC, DNA-protein crosslink, Animals, Humans, DSB, double-strand break, TLS, translesion synthesis, CtIP, C-terminal-binding protein interacting protein, S. cerevisiae, Saccharomyces cerevisiae, IR, ionising radiation, MAFFT, multiple alignment using fast fourier transform, XPF, Xeroderma Pigmentosum group F-complementing protein, Wss1, weak suppressor of Smt3-1, ATM, ataxia-telangiectasia mutated, TDP1/2, tyrosyl-DNA phosphodiesterase 1/2, DNA, UV, ultraviolet, Ageing, SPRTN, SprT-like N-terminal domain, APC, anaphase promoting complex, Proteolysis, ETO, etoposide, HR, homologous recombination
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e5438d87ad1b1061b50aef98e3fe56a
https://doi.org/10.1016/j.dnarep.2018.08.025 -
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المؤلفون: Mikhail I. Shtilman, Oxana V. Klimenko
المصدر: Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 186-192 (2019)مصطلحات موضوعية: Amphiphilic poly-(N-vinylpyrrolidone), Colorectal cancer, Health, Toxicology and Mutagenesis, Polymer carriers, CaCo2 colorectal adenocarcinoma, 010501 environmental sciences, Toxicology, 01 natural sciences, Regulatory molecules, KIR1DL2, CD158b, expressed on natural killer cells and a subset of T cells, TE, transposon elements, 0302 clinical medicine, PIWIL1, piwi-like protein 1, RB1, retinoblastoma 1, Colorectal adenocarcinoma, H3K9me3, tri-methyl lysine 9 of histone H3, FGF2, fibroblast growth factor 2, OCT4, octamer-binding transcription factor 4, medicine.diagnostic_test, Chemistry, mTOR, mechanistic target of rapamycin, Wnt-1, wingless type MMTV integration site family, member 1, Embryo, Transfection, iPS, induced pluripotent stem cells, MKI-67, marker of proliferation ki-67, Cell biology, piR, piwi-interacting RNA, P-element induced wimpy testis interacting RNA, miRNA-152, ERK1/2, extracellular signal regulated kinase ½, Reprogramming, HOXA10, homebox A10, HILI, human piwi, TNFRS6B, TNF receptor superfamily 6B, BACH1, BTB domain and CNC homolog 1, CD, cluster of differentiation, piRNA-30074, TGFBR2, transforming growth factor beta receptor 2, Immunofluorescence, DTT, dithyothreitol, Article, 03 medical and health sciences, lcsh:RA1190-1270, SncRNAs, small non-coding RNAs, VMAF, musculoaponeurotic fibrosarcoma, medicine, DNMT1, DNA methyltransferase 1, 0105 earth and related environmental sciences, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, AGO2, argonaute 2, DICER1, ribonuclease III, medicine.disease, TSS, transcriptional start sites, IL, interleukin, GITR3A, glucocorticoid-induced TNFR-related protein, Transformation (genetics), ICOS1B, inducible T-cell co-stimulator, PNVP, poly-(N-vinylpyrrolidone), 030217 neurology & neurosurgery, HMOX1, heme oxygenase 1, miR, micro-RNA
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المؤلفون: Yunyi Yao, David A. Lawrence, Kevin Manley, Tapan K. Mondal, Qishan Lin, Rosemary Matala, Mohammad Nizam Uddin
المصدر: Brain, Behavior, & Immunity-Health, Vol 4, Iss, Pp 100069-(2020)
Brain, Behavior, & Immunity-Healthمصطلحات موضوعية: Alpha-enolase, ASD, autism spectrum disorder, Dnmt1, DNA Methyltransferase 1, Eno1, alpha-enolase, IL21R, interleukin-21 receptor, Autism, Ag, antigen, Neurosciences. Biological psychiatry. Neuropsychiatry, Plasma cell, Ab, antibody, Lysine demethylase 6B, Tfh, T follicular helper cell, Autoantibody, Immune system, Antigen, Full Length Article, medicine, BTBR, Kdm6b, Lysine Demethylase 6B, T follicular helper cell, B cell, IL-21r, General Environmental Science, Pax5, biology, Kdm6b, Dlst, dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial, Pax5, Paired Box 5, medicine.anatomical_structure, Humoral immunity, Immunology, Dnmt1, BM, bone marrow, biology.protein, General Earth and Planetary Sciences, Antibody, CD8, RC321-571
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المؤلفون: Christin L. Hanigan, Patrick M. Woster, Lihua Jin, Yu-Yu Wu, Ben Ho Park, Robert A. Casero, Wei-wei Wang
المصدر: Biochemical Journal
مصطلحات موضوعية: SWIRM, Swi3p/Rsc8p/Moira, AAV, adeno-associated viral, ATRA, all-trans retinoic acid, HDAC, histone deacetylase, Biochemistry, FAD-dependent oxidase, Histones, Gene Knockout Techniques, Mice, 0302 clinical medicine, H3K4, histone H3 Lys4, Cluster Analysis, histone modification, DNA (Cytosine-5-)-Methyltransferases, Cancer epigenetics, VAT1L, vesicle amine transport protein 1 homologue-like, Oligonucleotide Array Sequence Analysis, Histone Demethylases, 0303 health sciences, biology, SET7/9, SET domain-containing histone methyltransferase 7/9, me3, trimethyl, H3K9ac, H3K9 acetylation, LSD, lysine-specific demethylase, ChIP, chromatin immunoprecipitation, Gene Expression Regulation, Neoplastic, Histone, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, CoREST, RE1-silencing transcription factor corepressor 1, 030220 oncology & carcinogenesis, Colonic Neoplasms, Female, Research Article, SEPT, synthetic exon promoter trap, DNA (Cytosine-5-)-Methyltransferase 1, animal structures, COBRA, combined bisulfite restriction analysis, PCNA, proliferating cell nuclear antigen, Blotting, Western, Transplantation, Heterologous, Mice, Nude, Methylation, DNA methyltransferase, HEK, human embryonic kidney, 03 medical and health sciences, Histone H3, TSS, transcriptional start site, LINE-1, long interspersed nucleotide element 1, transcriptional repression, DNMT1, DNA methyltransferase 1, Animals, Humans, Gene silencing, Molecular Biology, Gene knockout, Cell Proliferation, 030304 developmental biology, epigenetics, VIM, vimentin, Gene Expression Profiling, Lysine, ES, embryonic stem, H3K9, histone H3 Lys9, me2, dimethyl, pAAV, AAV plasmid, Neoplasms, Experimental, Cell Biology, DNA Methylation, HCT116 Cells, Molecular biology, AOL, amine oxidase-like, JARID1, Jumonji, AT rich interactive domain 1, HA, homology arm, DNMT1, biology.protein, chromatin, Demethylase, me1, monomethyl, qPCR, quantitative PCR, Tumor Suppressor Protein p53
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0178742d1ad71692360fd9805634f77f
https://doi.org/10.1042/bj20121360