المؤلفون: Tafreshi NK; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Kil H; Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, West Virginia 26506, United States.; Modulation Therapeutics, Inc., Morgantown, West Virginia 26506, United States., Pandya DN; Department of Radiology, University of Iowa Health Care, Iowa City, Iowa 52242, United States., Tichacek CJ; Departments of Radiation Oncology and Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Physics, University of South Florida, Tampa, Florida 33612, United States., Doligalski ML; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Budzevich MM; Small Animal Imaging Laboratory and Biostatistics and Bioinformatics Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Delva NC; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Langsen ML; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Vallas JA; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Boulware DC; Small Animal Imaging Laboratory and Biostatistics and Bioinformatics Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Engelman RW; Departments of Pediatrics, Pathology & Cell Biology and Department of Oncologic Sciences, University of South Florida, Tampa, Florida 33612, United States., Gage KL; Departments of Radiation Oncology and Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Moros EG; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Departments of Radiation Oncology and Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Physics, University of South Florida, Tampa, Florida 33612, United States.; Departments of Pediatrics, Pathology & Cell Biology and Department of Oncologic Sciences, University of South Florida, Tampa, Florida 33612, United States., Wadas TJ; Department of Radiology, University of Iowa Health Care, Iowa City, Iowa 52242, United States., McLaughlin ML; Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, West Virginia 26506, United States.; Modulation Therapeutics, Inc., Morgantown, West Virginia 26506, United States., Morse DL; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Physics, University of South Florida, Tampa, Florida 33612, United States.; Small Animal Imaging Laboratory and Biostatistics and Bioinformatics Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Departments of Pediatrics, Pathology & Cell Biology and Department of Oncologic Sciences, University of South Florida, Tampa, Florida 33612, United States.

المصدر: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2021 Mar 12; Vol. 4 (2), pp. 953-965. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

المؤلفون: Tichacek CJ; Department of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Physics, University of South Florida, Tampa, Florida 33620, United States., Tafreshi NK; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Kil H; Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, West Virginia 26506, United States., Engelman RW; Department of Pediatrics, Pathology and Cell Biology, University of South Florida, Tampa, Florida 33612, United States., Doligalski ML; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Budzevich MM; Department of Physics, University of South Florida, Tampa, Florida 33620, United States.; Small Animal Imaging Laboratory, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Gage KL; Department of Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., McLaughlin ML; Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, West Virginia 26506, United States.; Modulation Therapeutics Inc., Morgantown, West Virginia 26506, United States., Wadas TJ; Department of Radiology, University of Iowa, Iowa City, Iowa 52242, United States., Silva A; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States., Moros E; Department of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Physics, University of South Florida, Tampa, Florida 33620, United States.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida 33612, United States., Morse DL; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States.; Department of Physics, University of South Florida, Tampa, Florida 33620, United States.; Department of Pediatrics, Pathology and Cell Biology, University of South Florida, Tampa, Florida 33612, United States.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida 33612, United States.

المصدر: Molecular pharmaceutics [Mol Pharm] 2020 Nov 02; Vol. 17 (11), pp. 4180-4188. Date of Electronic Publication: 2020 Oct 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Alpha Particles/*therapeutic use , Melanoma/*drug therapy , Melanoma, Experimental/*drug therapy , Radiopharmaceuticals/*administration & dosage , Radiopharmaceuticals/*pharmacokinetics , Uveal Neoplasms/*drug therapy , alpha-MSH/*administration & dosage , alpha-MSH/*pharmacokinetics, Animals ; Cell Line, Tumor ; Ligands ; Melanoma/metabolism ; Melanoma/pathology ; Melanoma, Experimental/metabolism ; Melanoma, Experimental/pathology ; Metabolic Clearance Rate ; Mice ; Mice, Inbred BALB C ; Mice, SCID ; Molecular Targeted Therapy/methods ; Receptor, Melanocortin, Type 1/metabolism ; Tissue Distribution ; Treatment Outcome ; Tumor Burden/drug effects ; Uveal Neoplasms/metabolism ; Uveal Neoplasms/pathology ; Xenograft Model Antitumor Assays

SCR Disease Name: Uveal melanoma

المؤلفون: Tafreshi NK; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., Doligalski ML; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., Tichacek CJ; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., Pandya DN; Department of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Budzevich MM; Small Animal Imaging Laboratory, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., El-Haddad G; Depts. of Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., Khushalani NI; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA., Moros EG; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.; Department of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.; Department of Physics, University of South Florida, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., McLaughlin ML; Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, WV & Modulation Therapeutics Inc., 64 Medical Center Drive, Morgantown, WV 26506, USA., Wadas TJ; Department of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Morse DL; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.; Department of Physics, University of South Florida, Tampa, FL 33612, USA.; Small Animal Imaging Laboratory, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2019 Nov 26; Vol. 24 (23). Date of Electronic Publication: 2019 Nov 26.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Alpha Particles/*therapeutic use , Neoplasms/*radiotherapy , Radiopharmaceuticals/*therapeutic use, Animals ; Antibodies, Monoclonal/therapeutic use ; Humans ; Radioisotopes/therapeutic use ; Radiometry/methods

المؤلفون: Tafreshi NK; Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Tichacek CJ; Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Physics, University of South Florida, Tampa, Florida., Pandya DN; Department of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, North Carolina., Doligalski ML; Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Budzevich MM; Small Animal Imaging Laboratory, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Kil H; Department of Pharmaceutical Sciences, Health Sciences Center, West Virginia University, and Modulation Therapeutics Inc., Morgantown, West Virginia., Bhatt NB; Department of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, North Carolina., Kock ND; Section on Comparative Medicine, Department of Pathology, Wake Forest University Health Sciences, Winston-Salem, North Carolina., Messina JL; Departments of Anatomic Pathology and Cutaneous Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Dermatology, University of South Florida, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Ruiz EE; Small Animal Imaging Laboratory, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Delva NC; Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Weaver A; Division of Research Integrity and Compliance, University of South Florida, Tampa, Florida., Gibbons WR; Division of Research Integrity and Compliance, University of South Florida, Tampa, Florida., Boulware DC; Biostatistics Core Facility, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Khushalani NI; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., El-Haddad G; Departments of Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida; and., Triozzi PL; Department of Hematology and Oncology, Wake Forest University Health Sciences, Winston-Salem, North Carolina., Moros EG; Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Physics, University of South Florida, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., McLaughlin ML; Department of Pharmaceutical Sciences, Health Sciences Center, West Virginia University, and Modulation Therapeutics Inc., Morgantown, West Virginia., Wadas TJ; Department of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, North Carolina., Morse DL; Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida david.morse@moffitt.org.; Department of Physics, University of South Florida, Tampa, Florida.; Small Animal Imaging Laboratory, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.

المصدر: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2019 Aug; Vol. 60 (8), pp. 1124-1133. Date of Electronic Publication: 2019 Feb 07.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Targeted Therapy*, Melanoma/*radiotherapy , Receptor, Melanocortin, Type 1/*chemistry , Uveal Neoplasms/*radiotherapy, Alpha Particles ; Animals ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Chelating Agents/chemistry ; Female ; Humans ; Lanthanoid Series Elements/chemistry ; Male ; Maximum Tolerated Dose ; Mice ; Mice, Inbred BALB C ; Mice, SCID ; Neoplasm Metastasis ; Neoplasm Transplantation ; Prognosis ; Radiometry ; Radiopharmaceuticals/pharmacokinetics ; Rats ; Rats, Sprague-Dawley

المؤلفون: Huang X; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Pan Z; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Vascular Medicine, Tianjin Union Medicine Center, Tianjin, China., Doligalski ML; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Xiao X; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Pathology, Guangzhou University of Chinese Medicine, Guangzhou, China., Ruiz E; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Budzevich MM; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Tian H; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.

المصدر: Oncotarget [Oncotarget] 2017 Jul 18; Vol. 8 (29), pp. 46900-46914.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Fluorine Radioisotopes*/chemistry , Indoleamine-Pyrrole 2,3,-Dioxygenase*/antagonists & inhibitors , Positron-Emission Tomography*/methods , Radioactive Tracers* , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/pharmacology, Neoplasms/*diagnostic imaging, Animals ; Cell Line, Tumor ; Disease Models, Animal ; Enzyme Activation/drug effects ; Female ; Heterografts ; Humans ; Immunohistochemistry ; Mice ; Neoplasms/immunology ; Neoplasms/pathology ; Protein Binding