المؤلفون: Snieckute G; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Ryder L; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Vind AC; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Wu Z; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Arendrup FS; Biotech Research and Innovation Center, University of Copenhagen, DK-2200 Copenhagen, Denmark., Stoneley M; MRC Toxicology Unit, University of Cambridge, Cambridge CB2 1QR, UK., Chamois S; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland., Martinez-Val A; Mass Spectrometry for Quantitative Proteomics, Proteomics Program, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark., Leleu M; Bioinformatics Competence Center, Ecole Polytechnique Fédérale de Lausanne and University of Lausanne, CH-1015 Lausanne, Switzerland., Dreos R; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland., Russell A; Department of Biology, University of York, York YO10 5DD, UK., Gay DM; Biotech Research and Innovation Center, University of Copenhagen, DK-2200 Copenhagen, Denmark., Genzor AV; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Choi BS; Department of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Basse AL; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Sass F; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Dall M; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Dollet LCM; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Blasius M; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Willis AE; MRC Toxicology Unit, University of Cambridge, Cambridge CB2 1QR, UK., Lund AH; Biotech Research and Innovation Center, University of Copenhagen, DK-2200 Copenhagen, Denmark., Treebak JT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Olsen JV; Mass Spectrometry for Quantitative Proteomics, Proteomics Program, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark., Poulsen SS; Department of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Pownall ME; Department of Biology, University of York, York YO10 5DD, UK., Jensen BAH; Department of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Clemmensen C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Gerhart-Hines Z; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Gatfield D; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland., Bekker-Jensen S; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Center for Gene Expression, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.

المصدر: Science (New York, N.Y.) [Science] 2023 Dec 08; Vol. 382 (6675), pp. eadf3208. Date of Electronic Publication: 2023 Dec 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Aging*/metabolism , MAP Kinase Kinase Kinase 3*/genetics , MAP Kinase Kinase Kinase 3*/metabolism , Obesity*/metabolism , Reactive Oxygen Species*/metabolism , Ribosomes*/metabolism , Stress, Physiological*, Animals ; Mice ; Protein Biosynthesis ; Zebrafish ; Mice, Knockout