المؤلفون: M Kholosy W; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Derieppe M; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., van den Ham F; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Ober K; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Su Y; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Custers L; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Schild L; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., M J van Zogchel L; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., M Wellens L; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., R Ariese H; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Szanto CL; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Wienke J; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Dierselhuis MP; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., van Vuurden D; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Dolman EM; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands., Molenaar JJ; Princess Máxima Center for Paediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.

المصدر: Journal of personalized medicine [J Pers Med] 2021 Aug 30; Vol. 11 (9). Date of Electronic Publication: 2021 Aug 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE

المؤلفون: Decaesteker B; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium. bieke.decaesteker@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium. bieke.decaesteker@ugent.be., Denecker G; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Van Neste C; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Dolman EM; Princess Máxima Center for Pediatric Oncology, Department of Translational Research, Utrecht, 3584, The Netherlands., Van Loocke W; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Gartlgruber M; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Nunes C; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., De Vloed F; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Depuydt P; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Verboom K; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Rombaut D; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Loontiens S; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., De Wyn J; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Kholosy WM; Princess Máxima Center for Pediatric Oncology, Department of Translational Research, Utrecht, 3584, The Netherlands., Koopmans B; Princess Máxima Center for Pediatric Oncology, Department of Translational Research, Utrecht, 3584, The Netherlands., Essing AHW; Princess Máxima Center for Pediatric Oncology, Department of Translational Research, Utrecht, 3584, The Netherlands., Herrmann C; Institute of Pharmacy and Molecular Biotechnology, and Bioquant Center, University of Heidelberg, Im Neuenheimer Feld 267, Heidelberg, 69120, Germany.; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany., Dreidax D; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Durinck K; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Deforce D; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium.; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, 9000, Belgium., Van Nieuwerburgh F; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium.; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, 9000, Belgium., Henssen A; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, 13353, Germany.; German Cancer Consortium (DKTK), Heidelberg, 69120, Germany.; Berlin Institute of Health, Berlin, 13353, Germany., Versteeg R; Department of Oncogenomics, Academic Medical Center, Amsterdam, 1105, AZ, Netherlands., Boeva V; Institut Cochin, INSERM U1016, CNRS UMR 8104, Paris Descartes University UMR-S1016, Paris, 75014, France., Schleiermacher G; Institut Curie, PSL Research University, Equipe Labellisée Ligue contre le Cancer, Laboratory Recherche Translationnelle en Oncologie Pédiatrique (RTOP), Laboratoire 'Gilles Thomas', Institut Curie, Department of Translational Research, Institut Curie, SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, 75248, France., van Nes J; Department of Oncogenomics, Academic Medical Center, Amsterdam, 1105, AZ, Netherlands., Mestdagh P; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Vanhauwaert S; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Schulte JH; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, 13353, Germany., Westermann F; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Molenaar JJ; Princess Máxima Center for Pediatric Oncology, Department of Translational Research, Utrecht, 3584, The Netherlands., De Preter K; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Speleman F; Center for Medical Genetics, Ghent University, Ghent, 9000, Belgium. Franki.speleman@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium. Franki.speleman@ugent.be.

المصدر: Nature communications [Nat Commun] 2018 Nov 19; Vol. 9 (1), pp. 4866. Date of Electronic Publication: 2018 Nov 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Brain Neoplasms/*genetics , Forkhead Box Protein M1/*genetics , Kv Channel-Interacting Proteins/*genetics , N-Myc Proto-Oncogene Protein/*genetics , Neuroblastoma/*genetics , Repressor Proteins/*genetics , T-Box Domain Proteins/*genetics, Antineoplastic Agents/pharmacology ; Azepines/pharmacology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cyclin-Dependent Kinases/genetics ; Cyclin-Dependent Kinases/metabolism ; DNA Copy Number Variations ; Epigenesis, Genetic ; Forkhead Box Protein M1/metabolism ; HEK293 Cells ; Histones/genetics ; Histones/metabolism ; Humans ; Kv Channel-Interacting Proteins/metabolism ; N-Myc Proto-Oncogene Protein/metabolism ; Neuroblastoma/drug therapy ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Organoids/drug effects ; Organoids/metabolism ; Organoids/pathology ; Panobinostat/pharmacology ; Phenylenediamines/pharmacology ; Pyrimidines/pharmacology ; Repressor Proteins/metabolism ; Signal Transduction ; T-Box Domain Proteins/metabolism ; Triazoles/pharmacology ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Cyclin-Dependent Kinase-Activating Kinase

المؤلفون: Gholizadeh S; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Dolman EM; Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, the Netherlands., Wieriks R; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Sparidans RW; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Hennink WE; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Kok RJ; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands. r.j.kok@uu.nl.

المصدر: Pharmaceutical research [Pharm Res] 2018 Mar 07; Vol. 35 (4), pp. 85. Date of Electronic Publication: 2018 Mar 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*administration & dosage , Drug Compounding/*methods , Imidazoles/*administration & dosage , Naphthoquinones/*administration & dosage , Neuroblastoma/*drug therapy, Animals ; Antibodies/immunology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacokinetics ; Cell Line, Tumor ; Drug Liberation ; Drug Stability ; Female ; Gangliosides/immunology ; Gangliosides/metabolism ; Half-Life ; Humans ; Hydrophobic and Hydrophilic Interactions ; Imidazoles/chemistry ; Imidazoles/pharmacokinetics ; Injections, Intravenous ; Liposomes ; Mice ; Mice, Nude ; Naphthoquinones/chemistry ; Naphthoquinones/pharmacokinetics ; Neuroblastoma/immunology ; Neuroblastoma/pathology ; Pilot Projects ; Polyethylene Glycols/chemistry ; Survivin/antagonists & inhibitors ; Xenograft Model Antitumor Assays