المؤلفون: Salmon JM; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Australian Centre for Blood Diseases, Monash University and The Alfred Hospital, Melbourne, Australia., Todorovski I; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Stanley KL; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Bruedigam C; Cancer Program, Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Medicine, University of Queensland, Brisbane, Queensland, Australia., Kearney CJ; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Martelotto LG; Single Cell Innovation Lab, Department of Clinical Pathology, University of Melbourne, Parkville, Victoria, Australia., Rossello F; Single Cell Innovation Lab, Department of Clinical Pathology, University of Melbourne, Parkville, Victoria, Australia.; University of Melbourne Centre for Cancer Research, The University of Melbourne, Melbourne, Victoria, Australia., Semple T; Molecular Genomics Core, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Arnau GM; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.; Molecular Genomics Core, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Zethoven M; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Bots M; Laboratory of Clinical Chemistry, Academic Medical Center, University of Amsterdam, the Netherlands., Bjelosevic S; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Cluse LA; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Fraser PJ; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Litalien V; Australian Centre for Blood Diseases, Monash University and The Alfred Hospital, Melbourne, Australia., Vidacs E; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., McArthur K; Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia., Matthews AY; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, Monash University Clayton Victoria, Australia., Gressier E; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., de Weerd NA; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, Monash University Clayton Victoria, Australia., Lichte J; Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, Düsseldorf, Germany., Kelly MJ; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Hogg SJ; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Hertzog PJ; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, Monash University Clayton Victoria, Australia., Kats LM; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Vervoort SJ; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., De Carvalho DD; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Scheu S; Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, Düsseldorf, Germany., Bedoui S; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia., Kile BT; Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia., Lane SW; Cancer Program, Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Medicine, University of Queensland, Brisbane, Queensland, Australia., Perkins AC; Australian Centre for Blood Diseases, Monash University and The Alfred Hospital, Melbourne, Australia., Wei AH; Australian Centre for Blood Diseases, Monash University and The Alfred Hospital, Melbourne, Australia., Dominguez PM; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Johnstone RW; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.

المصدر: Cancer discovery [Cancer Discov] 2022 Jun 02; Vol. 12 (6), pp. 1560-1579.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/metabolism, Cell Differentiation ; Dendritic Cells ; Epigenesis, Genetic ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylase Inhibitors/therapeutic use ; Histone Deacetylases/genetics ; Humans ; Panobinostat/pharmacology

المؤلفون: Ali AI; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Wang M; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., von Scheidt B; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia., Dominguez PM; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Harrison AJ; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia., Tantalo DGM; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia., Kang J; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Oliver AJ; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Chan JD; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Du X; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Bai Y; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Lee B; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.; Divsion of Systems Biology and Personalised Medicine, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Johnstone RW; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.; Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Darcy PK; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Kershaw MH; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia. clare.slaney@petermac.org michael.kershaw@petermac.org.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Slaney CY; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia. clare.slaney@petermac.org michael.kershaw@petermac.org.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Nov 15; Vol. 27 (22), pp. 6222-6234. Date of Electronic Publication: 2021 Sep 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/therapy , Receptors, Chimeric Antigen*, Animals ; Cell Line, Tumor ; Histone Deacetylase Inhibitors/pharmacology ; Humans ; Immunotherapy, Adoptive/methods ; Mice ; Panobinostat ; Receptors, Antigen, T-Cell/genetics ; T-Lymphocytes ; Xenograft Model Antitumor Assays

المؤلفون: Lelliott EJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Kong IY; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Zethoven M; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Ramsbottom KM; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Martelotto LG; Single Cell Innovation Laboratory, The University of Melbourne, Parkville, Victoria, Australia., Meyran D; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Université de Paris, INSERM, U976 HIPI Unit, Institut de Recherche Saint-Louis, Paris, France., Zhu JJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Costacurta M; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Kirby L; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Sandow JJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Lim L; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Dominguez PM; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Todorovski I; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Haynes NM; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia., Beavis PA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Neeson PJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Hawkins ED; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., McArthur GA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Parish IA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Johnstone RW; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Oliaro J; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.; Department of Immunology, Central Clinical School, Monash University, Melbourne, Victoria, Australia., Sheppard KE; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. conor.kearney@petermac.org karen.sheppard@petermac.org stephin.vervoort@petermac.org.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia., Kearney CJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. conor.kearney@petermac.org karen.sheppard@petermac.org stephin.vervoort@petermac.org.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Vervoort SJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. conor.kearney@petermac.org karen.sheppard@petermac.org stephin.vervoort@petermac.org.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

المصدر: Cancer discovery [Cancer Discov] 2021 Oct; Vol. 11 (10), pp. 2582-2601. Date of Electronic Publication: 2021 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Breast Neoplasms/*drug therapy , Piperazines/*therapeutic use , Protein Kinase Inhibitors/*therapeutic use , Pyridines/*therapeutic use, Animals ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cyclin-Dependent Kinase 4/antagonists & inhibitors ; Cyclin-Dependent Kinase 6/antagonists & inhibitors ; Female ; Humans ; Memory T Cells/drug effects ; Mice ; Piperazines/pharmacology ; Protein Kinase Inhibitors/pharmacology ; Pyridines/pharmacology ; Xenograft Model Antitumor Assays

المؤلفون: Rosikiewicz W; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Chen X; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Dominguez PM; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, USA., Ghamlouch H; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Aoufouchi S; CNRS UMR8200, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Bernard OA; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Melnick A; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, USA., Li S; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; The Jackson Laboratory Cancer Center, Bar Harbor, ME, USA.; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT, USA.; Department of Computer Science and Engineering, University of Connecticut, Storrs, CT, USA.

المصدر: Science advances [Sci Adv] 2020 Jun 17; Vol. 6 (25), pp. eaay5872. Date of Electronic Publication: 2020 Jun 17 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: eCollection Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Dominguez PM; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York., Ghamlouch H; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Rosikiewicz W; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut., Kumar P; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut., Béguelin W; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York., Fontán L; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York., Rivas MA; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York., Pawlikowska P; CNRS UMR8200, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Armand M; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France.; CNRS UMR8200, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Mouly E; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Torres-Martin M; Sylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami, Miller School of Medicine, Miami, Florida., Doane AS; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York.; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York., Calvo Fernandez MT; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York., Durant M; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York., Della-Valle V; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Teater M; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York.; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York., Cimmino L; Department of Pathology, Laura and Isaac Perlmutter Cancer Center, and The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York., Droin N; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Tadros S; Department of Lymphoma/Myeloma and Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Motanagh S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York., Shih AH; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, New York., Rubin MA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York., Tam W; Pathology and Laboratory Medicine Department, Weill Cornell Medicine, New York, New York., Aifantis I; Department of Pathology, Laura and Isaac Perlmutter Cancer Center, and The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York., Levine RL; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, New York., Elemento O; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York., Inghirami G; Pathology and Laboratory Medicine Department, Weill Cornell Medicine, New York, New York., Green MR; Department of Lymphoma/Myeloma and Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Figueroa ME; Sylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami, Miller School of Medicine, Miami, Florida., Bernard OA; INSERM U1170, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France. amm2014@med.cornell.edu olivier.bernard@inserm.fr Said.AOUFOUCHI@gustaveroussy.fr sheng.li@jax.org rshaknovich@gmail.com., Aoufouchi S; CNRS UMR8200, équipe labelisée Ligue Nationale Contre le Cancer, Gustave Roussy, Université Paris-Saclay, Villejuif, France. amm2014@med.cornell.edu olivier.bernard@inserm.fr Said.AOUFOUCHI@gustaveroussy.fr sheng.li@jax.org rshaknovich@gmail.com., Li S; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut. amm2014@med.cornell.edu olivier.bernard@inserm.fr Said.AOUFOUCHI@gustaveroussy.fr sheng.li@jax.org rshaknovich@gmail.com.; The Jackson Laboratory Cancer Center, Bar Harbor, Maine.; Department of Genetics and Genome Sciences, University of Connecticut School of Medicine, Farmington, Connecticut., Shaknovich R; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York. amm2014@med.cornell.edu olivier.bernard@inserm.fr Said.AOUFOUCHI@gustaveroussy.fr sheng.li@jax.org rshaknovich@gmail.com.; Cancer Genetics, Inc., Rutherford, New Jersey., Melnick AM; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York. amm2014@med.cornell.edu olivier.bernard@inserm.fr Said.AOUFOUCHI@gustaveroussy.fr sheng.li@jax.org rshaknovich@gmail.com.

المصدر: Cancer discovery [Cancer Discov] 2018 Dec; Vol. 8 (12), pp. 1632-1653. Date of Electronic Publication: 2018 Oct 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation/*genetics , DNA-Binding Proteins/*genetics , Germinal Center/*metabolism , Lymphoma, Large B-Cell, Diffuse/*genetics , Plasma Cells/*metabolism , Proto-Oncogene Proteins/*genetics, Animals ; CREB-Binding Protein/genetics ; CREB-Binding Protein/metabolism ; DNA-Binding Proteins/metabolism ; Dioxygenases ; Epigenesis, Genetic/genetics ; Gene Expression Profiling/methods ; Germinal Center/pathology ; Hematopoietic Stem Cells/metabolism ; Humans ; Hyperplasia ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Lymphoma, Large B-Cell, Diffuse/pathology ; Mice, Knockout ; Mice, Transgenic ; Mutation ; Plasma Cells/pathology ; Positive Regulatory Domain I-Binding Factor 1/genetics ; Positive Regulatory Domain I-Binding Factor 1/metabolism ; Proto-Oncogene Proteins/metabolism

المؤلفون: Rutherford SC; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Fachel AA; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Li S; The Jackson Laboratory for Genomic Medicine and The Jackson Laboratory Cancer Center, University of Connecticut Health, Farmington, CT., Sawh S; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Muley A; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Ishii J; Epigenomics Core, Weill Cornell Medicine, New York, NY., Saxena A; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Dominguez PM; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Caldas Lopes E; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Agirre X; Division of Hemato-Oncology, Center for Applied Medical Research CIMA, University of Navarra, Ciberonc, Pamplona, Spain., Chambwe N; Institute for Systems Biology, Seattle, WA., Correa F; Memorial Sloan Kettering Cancer Center, New York, NY., Jiang Y; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Richards KL; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY., Betel D; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY; and., Shaknovich R; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY.; Cancer Genetics Inc, Rutherford, NJ.

المصدر: Blood [Blood] 2018 Aug 16; Vol. 132 (7), pp. e13-e23. Date of Electronic Publication: 2018 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Vesicles/*metabolism , Lymphoma, Large B-Cell, Diffuse/*metabolism , Neoplasm Proteins/*metabolism , RNA, Neoplasm/*metabolism, Cell Line, Tumor ; Extracellular Vesicles/genetics ; Extracellular Vesicles/pathology ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/pathology ; Neoplasm Proteins/genetics ; RNA, Neoplasm/genetics

المؤلفون: Teater M; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, 10021, USA.; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10021, USA., Dominguez PM; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, 10021, USA., Redmond D; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10021, USA., Chen Z; Division of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, NY, 10021, USA., Ennishi D; Centre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada., Scott DW; Centre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada., Cimmino L; Department of Pathology, Laura and Isaac Perlmutter Cancer Center, and The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY, 10016, USA., Ghione P; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, 10021, USA.; Division of Hematology, Department of Experimental Medicine and Oncology, University of Turin, 10124, Turin, Italy., Chaudhuri J; Immunology Program, Memorial Sloan-Kettering Cancer Center, Gerstner Sloan-Kettering Graduate School, New York, NY, 10021, USA., Gascoyne RD; Department of Pathology, British Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada., Aifantis I; Department of Pathology, Laura and Isaac Perlmutter Cancer Center, and The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY, 10016, USA., Inghirami G; Pathology and Laboratory Medicine Department, Weill Cornell Medicine, New York, NY, 10021, USA., Elemento O; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10021, USA. ole2001@med.cornell.edu.; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA. ole2001@med.cornell.edu., Melnick A; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, 10021, USA. amm2014@med.cornell.edu., Shaknovich R; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, 10021, USA. rshaknovich@gmail.com.; Cancer Genetics, Inc., Rutherford, NJ, 07070, USA. rshaknovich@gmail.com.

المصدر: Nature communications [Nat Commun] 2018 Jan 15; Vol. 9 (1), pp. 222. Date of Electronic Publication: 2018 Jan 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic*, Cytidine Deaminase/*genetics , Germinal Center/*metabolism , Lymphoma, Large B-Cell, Diffuse/*genetics, Animals ; B-Lymphocytes/metabolism ; B-Lymphocytes/pathology ; Cytidine Deaminase/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphoma, Large B-Cell, Diffuse/enzymology ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Mutation

المؤلفون: Dominguez PM; aDivisions of Hematology and Medical Oncology, Department of Medicine bDepartments of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine cDepartment of Pathology, Mount Sinai School of Medicine, New York, New York, USA., Teater M, Shaknovich R

المصدر: Current opinion in hematology [Curr Opin Hematol] 2017 Jul; Vol. 24 (4), pp. 402-408.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Lippincott Williams And Wilkins Country of Publication: United States NLM ID: 9430802 Publication Model: Print Cited Medium: Internet ISSN: 1531-7048 (Electronic) Linking ISSN: 10656251 NLM ISO Abbreviation: Curr Opin Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic* , Gene Expression Regulation, Neoplastic* , Genetic Heterogeneity*, Leukemia, B-Cell/*genetics , Lymphoma, B-Cell/*genetics, Animals ; DNA Methylation ; Germinal Center/metabolism ; Humans ; Leukemia, B-Cell/diagnosis ; Leukemia, B-Cell/metabolism ; Lymphoma, B-Cell/diagnosis ; Lymphoma, B-Cell/metabolism ; Signal Transduction

المؤلفون: Jiang Y; aWeill Cornell Cancer Center bDepartment of Physiology and Biophysics cDepartment of Medicine, Weill Cornell Medicine, New York City, New York, USA., Dominguez PM, Melnick AM

المصدر: Current opinion in hematology [Curr Opin Hematol] 2016 Jul; Vol. 23 (4), pp. 377-84.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Lippincott Williams And Wilkins Country of Publication: United States NLM ID: 9430802 Publication Model: Print Cited Medium: Internet ISSN: 1531-7048 (Electronic) Linking ISSN: 10656251 NLM ISO Abbreviation: Curr Opin Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic* , Gene Expression Regulation, Neoplastic*, Lymphoma, B-Cell/*genetics, Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Chromatin/genetics ; Chromatin/metabolism ; Clonal Evolution/genetics ; Cytosine/metabolism ; DNA Methylation ; DNA-Binding Proteins/metabolism ; Dioxygenases ; Enhancer Elements, Genetic ; Gene Silencing ; Genes, Tumor Suppressor ; Germinal Center/metabolism ; Germinal Center/pathology ; Histone Methyltransferases ; Histone-Lysine N-Methyltransferase/genetics ; Histone-Lysine N-Methyltransferase/metabolism ; Humans ; Lymphoma, B-Cell/metabolism ; Lymphoma, B-Cell/mortality ; Lymphoma, B-Cell/therapy ; Lymphoma, Follicular/genetics ; Lymphoma, Follicular/metabolism ; Lymphoma, Follicular/mortality ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Lymphoma, Large B-Cell, Diffuse/mortality ; Mutation ; Prognosis ; Promoter Regions, Genetic ; Proto-Oncogene Proteins/metabolism ; Signal Transduction

المؤلفون: Dominguez PM; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA., Teater M; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA., Chambwe N; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065, USA., Kormaksson M; IBM Research, Rio de Janeiro 22290-240, Brazil., Redmond D; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065, USA., Ishii J; Epigenomics Core Facility, Weill Cornell Medical College, New York, NY 10065, USA., Vuong B; Immunology Program, Memorial Sloan-Kettering Cancer Center, Gerstner Sloan-Kettering Graduate School, New York, NY 10065, USA., Chaudhuri J; Immunology Program, Memorial Sloan-Kettering Cancer Center, Gerstner Sloan-Kettering Graduate School, New York, NY 10065, USA., Melnick A; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA., Vasanthakumar A; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Godley LA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Papavasiliou FN; Laboratories of Lymphocyte Biology and Molecular Parasitology, The Rockefeller University, New York, NY 10065, USA., Elemento O; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065, USA., Shaknovich R; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: rshaknovich@gmail.com.

المصدر: Cell reports [Cell Rep] 2015 Sep 29; Vol. 12 (12), pp. 2086-98. Date of Electronic Publication: 2015 Sep 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic*, B-Lymphocytes/*metabolism , Cytidine Deaminase/*metabolism , Germinal Center/*metabolism, Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; Cell Differentiation ; Cell Movement ; Cell Proliferation ; Conserved Sequence ; Cytidine Deaminase/genetics ; Cytidine Deaminase/immunology ; Cytosine/metabolism ; DNA Methylation ; Germinal Center/cytology ; Germinal Center/immunology ; Humans ; Lymphocyte Activation ; Mice ; Mice, Inbred BALB C ; Mice, Knockout