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1دورية أكاديمية
المؤلفون: Kishore Polireddy, Mohiuddin Md Taimur Khan, Hemantkumar Chavan, Susan Young, Xiaochao Ma, Anna Waller, Matthew Garcia, Dominique Perez, Stephanie Chavez, Jacob J Strouse, Mark K Haynes, Cristian G Bologa, Tudor I Oprea, George P Tegos, Larry A Sklar, Partha Krishnamurthy
المصدر: PLoS ONE, Vol 7, Iss 7, p e40005 (2012)
وصف الملف: electronic resource
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2
المصدر: Semin Cancer Biol
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cellular differentiation, Antineoplastic Agents, Article, 03 medical and health sciences, Cyclic nucleotide, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, Cyclic AMP, medicine, Animals, Humans, Cyclic GMP, Acute leukemia, Leukemia, Cell growth, Drug Repositioning, medicine.disease, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Cancer research, cAMP-dependent pathway, ATP-Binding Cassette Transporters, Efflux, Intracellular
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3
المؤلفون: Barbara De Moerloose, Serge Van Calenbergh, Wojciech Ornatowski, Steven Goossens, Sofie Peirs, Alexandre Chigaev, Wouter Van Loocke, Charles G. Mullighan, Pieter Van Vlierberghe, Christian K. Nickl, Takeshi Takarada, Mignon L. Loh, Eliseo F. Castillo, Laurence C. Cheung, Dominique Perez, Béatrice Lintermans, Yukio Yoneda, Frederik W. van Delft, Richard B. Lock, Stuart S. Winter, Juliette Roels, Stephen P. Hunger, Lisa Demoen, Lindy Reunes, Ksenia Matlawska-Wasowska, Larry A. Sklar, Monique Nysus, Rishi S. Kotecha, Tim Lammens, Huining Kang, Dieter Deforce, Tim Pieters, Nitesh D. Sharma, Filip Van Nieuwerburgh, Martijn D. P. Risseeuw, Seth D. Merkley, Filip Matthijssens
المصدر: J Clin Invest
JOURNAL OF CLINICAL INVESTIGATIONمصطلحات موضوعية: 0301 basic medicine, CHEMOKINE RECEPTOR CXCR4, Core Binding Factor Alpha 1 Subunit, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, BETA-CATENIN, Mice, 0302 clinical medicine, Immunophenotyping, Medicine and Health Sciences, TRANSCRIPTION, Child, Gene Rearrangement, Organelle Biogenesis, GENE-EXPRESSION SIGNATURES, TARGETING SURVIVIN, Gene Expression Regulation, Developmental, Cell migration, General Medicine, LINEAGE, Gene Expression Regulation, Neoplastic, Chemotaxis, Leukocyte, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Disease Progression, Stem cell, STEM-CELLS, Myeloid-Lymphoid Leukemia Protein, Research Article, Signal Transduction, Receptors, CXCR4, T cell, ACUTE MYELOID-LEUKEMIA, Biology, In Vitro Techniques, Core Binding Factor beta Subunit, OSTEOBLAST DIFFERENTIATION, 03 medical and health sciences, Downregulation and upregulation, stomatognathic system, Cell Line, Tumor, medicine, Animals, Humans, RNA, Messenger, Transcription factor, B cell, DRUG-RESISTANCE, Chemotaxis, Histone-Lysine N-Methyltransferase, Hematopoiesis, 030104 developmental biology, Cancer research
وصف الملف: application/pdf
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4
المؤلفون: Virginie Bondu, Catherine E. Prudom Gineste, Bruce S. Edwards, Yang Wu, Larry A. Sklar, Dominique Perez, Tione Buranda, Kaylin R Lake
المصدر: SLAS Discovery. 23:634-645
مصطلحات موضوعية: 0301 basic medicine, Orthohantavirus, Cell Survival, Hantavirus Infections, viruses, Integrin, Andes virus, 030204 cardiovascular system & hematology, Antiviral Agents, Models, Biological, Biochemistry, Article, Virus, Analytical Chemistry, Flow cytometry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chlorocebus aethiops, medicine, Animals, Humans, Cytotoxicity, Vero Cells, PAC-1, Hantavirus, Dose-Response Relationship, Drug, medicine.diagnostic_test, biology, Chemistry, Sin Nombre virus, Reproducibility of Results, Virus Internalization, Flow Cytometry, Virology, High-Throughput Screening Assays, 030104 developmental biology, biology.protein, Molecular Medicine, Biomarkers, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314f6d16a015cf2d0511be428e4cda5a
https://doi.org/10.1177/2472555218766623 -
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المؤلفون: Alexandre Chigaev, Larry A. Sklar, Dominique Perez
المصدر: Pharmacol Ther
مصطلحات موضوعية: 0301 basic medicine, Antifungal, Drug, Optic Neuritis, medicine.drug_class, media_common.quotation_subject, Disease, Bioinformatics, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, 0302 clinical medicine, Anti-Infective Agents, Asian People, Neoplasms, medicine, Cyclic AMP, Animals, Humans, Pharmacology (medical), media_common, Pharmacology, business.industry, Clioquinol, Neurodegenerative Diseases, Syndrome, Japanese population, Myelitis, Cyclic AMP-Dependent Protein Kinases, 030104 developmental biology, Harm, 030220 oncology & carcinogenesis, Pharmacogenomics, ATP-Binding Cassette Transporters, Efflux, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03edcb31559402a6925d701aff89a09
https://europepmc.org/articles/PMC6571072/ -
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المؤلفون: Alexandre Chigaev, Ksenia Matlawska-Wasowska, Stuart S. Winter, Annette M. Evangelisti, Mark B. Carter, Larry A. Sklar, Matthew Garcia, Yelena Smagley, Dominique Perez
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Adenosine monophosphate, Programmed cell death, Cell Survival, Antineoplastic Agents, Apoptosis, Integrin alpha4beta1, Pharmacology, Second Messenger Systems, Adenylyl cyclase, 03 medical and health sciences, chemistry.chemical_compound, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Drug Discovery, Cyclic AMP, Tumor Cells, Cultured, Cyclic AMP Response Element-Binding Protein, Humans, Medicine, Phosphorylation, Membrane Potential, Mitochondrial, Dose-Response Relationship, Drug, drug repurposing, business.industry, Drug Repositioning, leukemia, Myeloid leukemia, U937 Cells, evasion of apoptosis, medicine.disease, efflux, High-Throughput Screening Assays, 3. Good health, Leukemia, 030104 developmental biology, Oncology, chemistry, Second messenger system, Efflux, Multidrug Resistance-Associated Proteins, business, Adenylyl Cyclases, Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6762379ae73ca492870e39a4c70abfdf
https://doi.org/10.18632/oncotarget.8986 -
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المؤلفون: Alexandre Chigaev, Larry A. Sklar, Bruce S. Edwards, Dominique Perez
المصدر: SLAS discovery : advancing life sciences RD. 23(7)
مصطلحات موضوعية: Drug, Computer science, media_common.quotation_subject, Drug Evaluation, Preclinical, Analysis models, Computational biology, Drug resistance, Biochemistry, Article, Analytical Chemistry, Flow cytometry, Software, Drug Discovery, medicine, Analysis software, Humans, Drug Interactions, Throughput (business), media_common, medicine.diagnostic_test, business.industry, Reproducibility of Results, Drug Synergism, Flow Cytometry, High-Throughput Screening Assays, Molecular Medicine, Drug Therapy, Combination, business, Nonlinear regression, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1fd570c817b2d9ab9d0dab1f7093d1
https://pubmed.ncbi.nlm.nih.gov/29842834 -
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المؤلفون: Dominique Perez, Stephen P. Hunger, Alexandre Chigaev, Michelle L. Hermiston, Cristina Delgado-Martin, Travis A. Woods, Bruce S. Edwards, Ksenia Matlawska-Wasowska, Anna Waller, Nitesh D. Sharma, Stuart S. Winter, Mignon L. Loh, Larry A. Sklar, Christian K. Nickl
المصدر: SLAS discovery : advancing life sciences R & D, vol 23, iss 7
مصطلحات موضوعية: 0301 basic medicine, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Biochemistry, Analytical Chemistry, Mice, 0302 clinical medicine, Drug Discovery, Medicine, kinase inhibitors, Cancer, Pediatric, Tumor, medicine.diagnostic_test, Kinase, leukemia, Hematology, Flow Cytometry, Small molecule, Drug repositioning, Leukemia, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Molecular Medicine, Drug, Development of treatments and therapeutic interventions, T-ALL, Biotechnology, Pediatric Cancer, High-throughput screening, Antineoplastic Agents, high-throughput screening, Article, Flow cytometry, Cell Line, Dose-Response Relationship, Small Molecule Libraries, 03 medical and health sciences, Rare Diseases, Cell Line, Tumor, Animals, Humans, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, business.industry, hypoxia, Drug Repositioning, Patient survival, medicine.disease, High-Throughput Screening Assays, 030104 developmental biology, Orphan Drug, Cancer research, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d09a3fbd8cba1c062b5dc9a71ba3c1
https://europepmc.org/articles/PMC6292518/ -
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المؤلفون: George P. Tegos, Richard S. Larson, J. Jacob Strouse, Virginia M. Salas, Mark B. Carter, Susan M. Young, Irena Ivnitski-Steele, Annette M. Evangelisti, Anna Waller, Tudor I. Oprea, Cristian Bologa, Larry A. Sklar, Oleg Ursu, Dominique Perez, Bruce S. Edwards
المصدر: Analytical Biochemistry. 437:77-87
مصطلحات موضوعية: ATP Binding Cassette Transporter, Subfamily B, Abcg2, Biophysics, ATP-binding cassette transporter, Plasma protein binding, Biochemistry, Article, Cell Line, Multidrug Resistance Protein 1, ATP Binding Cassette Transporter, Subfamily G, Member 2, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Molecular Biology, Fluorescent Dyes, P-glycoprotein, biology, Cell Biology, Flow Cytometry, Neoplasm Proteins, ABCC1, biology.protein, ATP-Binding Cassette Transporters, Efflux, Multidrug Resistance-Associated Proteins, Protein Binding
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المصدر: Methods in Molecular Biology ISBN: 9781493936717
مصطلحات موضوعية: 0301 basic medicine, Cell, Drug Evaluation, Preclinical, ATP-binding cassette transporter, Article, Flow cytometry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, medicine, Cyclic AMP, Humans, Cyclic adenosine monophosphate, Fluorescent Dyes, Leukemia, medicine.diagnostic_test, Chemistry, Biological Transport, Flow Cytometry, High-Throughput Screening Assays, Cytolysis, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, Cytoplasm, 030220 oncology & carcinogenesis, Cancer cell, ATP-Binding Cassette Transporters, Efflux
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172f6ba8cc68479b10756cedb00fd152
https://pubmed.ncbi.nlm.nih.gov/27316999