المؤلفون: John P. Anderson, Dean R. Artis, Hing L. Sham, Roy K. Hom, Michael S. Dappen, Andrei W. Konradi, Simeon Bowers, Hu Pan, Robert A. Galemmo, Marc Adler, Pearl Tanaka, May Lin, Jeanne Baker, Lany Ruslim, Donald J. Fauss, Zhao Ren, Yong L. Zhu, Anh P. Truong, Danny Tam, Marcelle Bergeron, Lee H. Latimer, Paul Beroza, Jacek Jagodzinski, Heather Zhang, Michael P. Bova, George Tonn, Linnea Diep, Ruth Motter, Kent Fitzgerald, Nanhua Yao, Wayman Chan, Jennifer K. Hoffman, R. Jeffrey Neitz, Danielle L. Aubele

المصدر: ChemMedChem. 8:1295-1313

مصطلحات موضوعية: Male, Parkinson's disease, Polo-like kinase, Molecular Dynamics Simulation, Protein Serine-Threonine Kinases, Pharmacology, Biology, Blood–brain barrier, Biochemistry, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Humans, Protein Isoforms, Phosphorylation, General Pharmacology, Toxicology and Pharmaceutics, Protein Kinase Inhibitors, Alpha-synuclein, Binding Sites, Kinase, Drug discovery, Organic Chemistry, Brain, medicine.disease, Protein Structure, Tertiary, Rats, HEK293 Cells, medicine.anatomical_structure, chemistry, Blood-Brain Barrier, alpha-Synuclein, Molecular Medicine, Female, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9de472a2de2bc218c1224fe31845aba
https://doi.org/10.1002/cmdc.201300166

المؤلفون: Kevin Tanaka, Marcelle Bergeron, Donald J. Fauss, Maria Armanda Viana Rodrigues, Jeanne Baker, Yangli Yang, Pui Seto, Monica You, Linnea Diep, Ruth Motter, Lilibeth Dofiles

المصدر: Journal of Neuroscience Methods. 215:245-257

مصطلحات موضوعية: Male, Parkinson's disease, Tyrosine 3-Monooxygenase, Dopamine, Biotin, Enzyme-Linked Immunosorbent Assay, Neuroprotection, Specimen Handling, Rats, Sprague-Dawley, Pathogenesis, Mice, Intermediate Filament Proteins, Western blot, medicine, Animals, Humans, Chromatography, High Pressure Liquid, biology, Tyrosine hydroxylase, medicine.diagnostic_test, General Neuroscience, Antibodies, Monoclonal, Brain, Parkinson Disease, medicine.disease, Molecular biology, Rats, Mice, Inbred C57BL, Disease Models, Animal, Animals, Newborn, Mutation, Immunology, biology.protein, Synuclein, Female, Antibody, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5158819f7abe898c2b26ab09be64b0
https://doi.org/10.1016/j.jneumeth.2013.03.012

المؤلفون: Jon R. Polansky, Donald J. Fauss, Carin C. Zimmerman

المصدر: Eye. 14:503-514

مصطلحات موضوعية: medicine.medical_specialty, Basic fibroblast growth factor, Cell Culture Techniques, Biology, Transfection, Dexamethasone, Green fluorescent protein, chemistry.chemical_compound, Trabecular Meshwork, Internal medicine, Gene expression, medicine, Humans, Coding region, RNA, Messenger, Eye Proteins, Glucocorticoids, Gene, Glycoproteins, Reverse Transcriptase Polymerase Chain Reaction, Cell biology, Cytoskeletal Proteins, Ophthalmology, medicine.anatomical_structure, Endocrinology, Gene Expression Regulation, chemistry, Cell culture, Triiodothyronine, Fibroblast Growth Factor 2, sense organs, Trabecular meshwork

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbfe214c77800791ed90387af2204ab
https://doi.org/10.1038/eye.2000.137

المؤلفون: Pu Chen, Donald J. Fauss, Ernest Bloom, Jon R. Polansky, Ron M. Kurtz, Elke Lütjen-Drecoll, Thai Nguyen, Hua Chen, Zhi-Dong Ma, Douglas H. Johnson

المصدر: Ophthalmologica. 211:126-139

مصطلحات موضوعية: Candidate gene, DNA, Complementary, Molecular Sequence Data, Cell Culture Techniques, Dexamethasone, Gene product, Trabecular Meshwork, Complementary DNA, medicine, Humans, Eye Proteins, Growth Substances, Glucocorticoids, Gene, Myocilin, Aged, DNA Primers, Glycoproteins, Regulation of gene expression, biology, Glaucoma, General Medicine, Transforming growth factor beta, Molecular biology, Sensory Systems, Cytoskeletal Proteins, Oxidative Stress, Ophthalmology, medicine.anatomical_structure, Gene Expression Regulation, biology.protein, Electrophoresis, Polyacrylamide Gel, sense organs, Trabecular meshwork

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb4cf60ce332739c103913813cdaca6
https://doi.org/10.1159/000310780

المؤلفون: Paul Beroza, Michael P. Bova, Jennifer K. Hoffman, Jennifer Sealy, Heather Zhang, Marcelle Bergeron, Linnea Diep, Danny Tam, Ruth Motter, Zhao Ren, R. Jeffrey Neitz, Danielle L. Aubele, Kent Fitzgerald, Michael Ye, Wayman Chan, Pearl Tanaka, Deepal Pandya, Donald J. Fauss, Andrei W. Konradi, John P. Anderson, Roy K. Hom, Dean R. Artis, Hing L. Sham, Robert A. Galemmo, George Tonn, Jeanne Baker, Lany Ruslim, Yong L. Zhu, Anh P. Truong, Michael S. Dappen, Simeon Bowers

المصدر: Bioorganicmedicinal chemistry letters. 23(9)

مصطلحات موضوعية: Parkinson's disease, Clinical Biochemistry, Substituent, Pharmaceutical Science, Administration, Oral, Cell Cycle Proteins, Polo-like kinase, Pharmacology, Protein Serine-Threonine Kinases, Biochemistry, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Proto-Oncogene Proteins, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Protein Kinase Inhibitors, Alpha-synuclein, Chemistry, Pteridines, Organic Chemistry, Brain, Highly selective, medicine.disease, Rats, medicine.anatomical_structure, Orally active, HEK293 Cells, Cerebral cortex, Drug Design, Microsomes, Liver, Molecular Medicine, Selectivity, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53291bed2d270abeea1ef72781386bf
https://pubmed.ncbi.nlm.nih.gov/23522834

المؤلفون: Donald J. Fauss, J. R. Polansky, C. C. Zimmerman

المصدر: Pathogenesis and Risk Factors of Glaucoma ISBN: 9783642643026

مصطلحات موضوعية: Genetics, Identification (biology), Visual field loss, Computational biology, Psychology, Gene, Practical implications

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::57ceb7b4f5ee57f4c8631949772583d5
https://doi.org/10.1007/978-3-642-60203-0_10

المؤلفون: Ge Ming Lui, Donald J. Fauss, Jorge A. Alvarado, Jon R. Polansky, Richard B. Crook

المصدر: Current eye research. 13(4)

مصطلحات موضوعية: medicine.medical_specialty, Vasoactive intestinal peptide, Biology, Epithelium, Cell Line, Adenylyl cyclase, Cellular and Molecular Neuroscience, Ciliary processes, chemistry.chemical_compound, Ciliary body, Fetus, Internal medicine, medicine, Extracellular, Humans, Receptor, Pigment Epithelium of Eye, Cells, Cultured, Cell Cycle, Ciliary Body, Fibroblasts, Molecular biology, Sensory Systems, Ophthalmology, medicine.anatomical_structure, Endocrinology, chemistry, Cell culture, Receptors, Vasoactive Intestinal Peptide, hormones, hormone substitutes, and hormone antagonists, Intracellular, Adenylyl Cyclases, Vasoactive Intestinal Peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd4eba0e428490a41685d758e1bf92f
https://pubmed.ncbi.nlm.nih.gov/8033589

المؤلفون: Jorge A. Alvarado, Donald J. Fauss, Zvi Friedman, Ron M. Kurtz, Jon R. Polansky

المصدر: International ophthalmology. 13(1-2)

مصطلحات موضوعية: Agonist, medicine.medical_specialty, Time Factors, genetic structures, Epinephrine, medicine.drug_class, Timolol, Glaucoma, Stimulation, Betaxolol, Propanolamines, Trabecular Meshwork, Internal medicine, medicine, Cyclic AMP, Humans, Beta blocker, Cells, Cultured, business.industry, medicine.disease, eye diseases, Ophthalmology, medicine.anatomical_structure, Endocrinology, sense organs, Trabecular meshwork, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6582075e85b34f4c194ab6c3848760
https://pubmed.ncbi.nlm.nih.gov/2545641

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