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1
المؤلفون: Richard G. Ball, Sheila M. Galloway, Katherine K. McGettigan, Harvey R. Wendt, Gregori J. Morriello, Jerry Di Salvo, Marat Vijay Reddy, Black Regina M, Amanda L. Hurley, Judy Morris, Scott D. Feighner, Eric Streckfuss, George A. Doss, Alka Bansal, Anthony Sanfiz, Scott D. Edmondson, Mary Struthers, Nancy N. Tsou, Jiafang He, Crystal McKnight, George M. Laws, Donna L. Hreniuk, Gino Salituro
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:1865-1870
مصطلحات موضوعية: Models, Molecular, Agonist, Pyrrolidines, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Pyrrolidine, chemistry.chemical_compound, Ethanolamine, Drug Discovery, medicine, Humans, Moiety, Receptor, Molecular Biology, Organic Chemistry, Biological activity, Adrenergic beta-Agonists, chemistry, Receptors, Adrenergic, beta-3, Molecular Medicine, Selectivity
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2
المؤلفون: Donna L. Hreniuk, Ann E. Weber, Gino Salituro, Michael A. Robbins, Liping Wang, Stephen D. Goble, Mary Struthers, Eloisa Watkins, Amanda L. Hurley, Richard A. Berger, Jiafang He, Eric Streckfuss, Emma R. Parmee, Alka Bansal, Bart Harper, Anthony Sanfiz, Jerry DiSalvo, Scott D. Feighner, Scott D. Edmondson, K. Lulu Howell, Linda Brockunier
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1895-1899
مصطلحات موضوعية: Stereochemistry, Adrenergic beta-Antagonists, Clinical Biochemistry, Pharmaceutical Science, Adrenergic beta-3 Receptor Agonists, Rodentia, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Amide, Acetamides, Drug Discovery, medicine, Animals, Structure–activity relationship, Benzamide, Receptor, Beta (finance), Molecular Biology, Chemistry, Organic Chemistry, medicine.disease, Overactive bladder, Benzamides, Molecular Medicine, Acetamide
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3
المؤلفون: Mark T. Goulet, Lex H.T. Van der Ploeg, Junying Wang, Scott D. Feighner, Jonathan R. Young, Oksana C. Palyha, Douglas J. MacNeil, Cherilyn Turner, Donna L. Hreniuk, Ronsar Eid, Andreas W. Sailer, Robert J. DeVita, Xinchun Tong, Danny Chaung, Myle Hoang, Lauren P. Shearman, Carina P. Tan, Peter Lin, Jie Pan, Sloan Stribling, Alison M. Strack, Andrew D. Howard, Ramon E. Camacho, Jinlong Jiang
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:5270-5274
مصطلحات موضوعية: Male, Quinuclidines, Melanin-concentrating hormone, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Binding, Competitive, Biochemistry, Chemical synthesis, Rats, Sprague-Dawley, Aminoquinoline, Eating, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Humans, Receptors, Somatostatin, Molecular Biology, Molecular Structure, Organic Chemistry, Quinoline, Antagonist, Stereoisomerism, In vitro, Rats, chemistry, Quinolines, Molecular Medicine, Biological Assay, Energy Metabolism, medicine.drug
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4
المؤلفون: Lex H.T. Van der Ploeg, Mark T. Goulet, Lehua Chang, Carina P. Tan, Donna L. Hreniuk, Andreas W. Sailer, Scott D. Feighner, Jinlong Jiang, Robert J. DeVita, Jie Pan, Peter Lin, Oksana C. Palyha, Douglas J. MacNeil, Nancy R. Morin, Myle Hoang, Andrew D. Howard
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:5275-5279
مصطلحات موضوعية: Melanin-concentrating hormone, medicine.drug_class, Stereochemistry, High-throughput screening, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Carboxamide, In Vitro Techniques, Binding, Competitive, Biochemistry, Chemical synthesis, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, mental disorders, Drug Discovery, medicine, Humans, Receptors, Somatostatin, Receptor, Molecular Biology, Molecular Structure, Organic Chemistry, Antagonist, Stereoisomerism, Combinatorial chemistry, In vitro, chemistry, 4-Aminoquinoline, Aminoquinolines, Molecular Medicine
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5
المؤلفون: Donna L. Hreniuk, Oksana C. Palyha, Van der Ploeg Lh, Douglas J. MacNeil, Andrew D. Howard, Scott D. Feighner, Maria A. Bednarek, Nancy R. Morin, Sadowski Sj
المصدر: Biochemistry. 40:9379-9386
مصطلحات موضوعية: medicine.medical_specialty, Growth-hormone-releasing hormone receptor, Melanin-concentrating hormone, Protein Conformation, Molecular Sequence Data, Peptides, Cyclic, Biochemistry, Cell Line, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Isomerism, Thyrotropin-releasing hormone receptor, Internal medicine, medicine, Humans, Amino Acid Sequence, Cysteine, Disulfides, Receptors, Pituitary Hormone, Receptor, Melanins, Alanine, Hypothalamic Hormones, Thyroid hormone receptor, integumentary system, Peptide Fragments, Pituitary Hormones, Endocrinology, Amino Acid Substitution, chemistry, Hormone receptor, sense organs, Melanocortin 1 receptor, Hormone
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المؤلفون: Zhizhen Zeng, Carina P. Tan, Qingyun Liu, Jie Pan, Christopher P. Austin, Takehiro Fukami, Andreas W. Sailer, Masaki Ihara, Scott D. Feighner, Makoto Ito, Nancy R. Morin, Sharon J. Sadowski, Alka Bansal, Hisashi Iwaasa, Terrence P. McDonald, Qingping Jiang, David J. Figueroa, Akio Kanatani, Andrew D. Howard, Akane Ishihara, Betty Ky, Lex H.T. Van der Ploeg, Hideki Sano, Masahiko Ito, Sheng Shung Pong, Douglas J. MacNeil, Donna L. Hreniuk
المصدر: Proceedings of the National Academy of Sciences. 98:7564-7569
مصطلحات موضوعية: Male, medicine.medical_specialty, Melanin-concentrating hormone, Chromosomes, Human, Pair 22, Molecular Sequence Data, Neuropeptide, CHO Cells, In situ hybridization, Biology, Transfection, Pertussis toxin, Energy homeostasis, Receptors, G-Protein-Coupled, Radioligand Assay, chemistry.chemical_compound, Cricetinae, Internal medicine, Chlorocebus aethiops, medicine, Animals, Humans, Amino Acid Sequence, Receptors, Pituitary Hormone, Northern blot, Receptor, In Situ Hybridization, Multidisciplinary, Base Sequence, Sequence Homology, Amino Acid, Cell Membrane, Brain, Chromosome Mapping, Biological Sciences, respiratory system, Recombinant Proteins, Melanin-concentrating hormone receptor, Oncorhynchus keta, Endocrinology, chemistry, Organ Specificity, Pituitary Gland, COS Cells, Female, Sequence Alignment, hormones, hormone substitutes, and hormone antagonists
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e3f3aae52683bd88155974da1fc050
https://doi.org/10.1073/pnas.121170598 -
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المؤلفون: Sheng-Shung Pong, Mark Abramovitz, Andrew D. Howard, Rino Stocco, Ploeg, Raman K. Bakshi, Stacia Kargman, Carina P. Tan, Donna L. Hreniuk, Margaret A. Cascieri, David J. Figueroa, Ravi P. Nargund, Karen K. McKee, Jilly F. Evans, Scott D. Feighner, Lex H. T. Van Der, Christopher P. Austin, Oksana C. Palyha, Roy G. Smith, Douglas J. MacNeil, Arthur A. Patchett, Gary P. O'Neill
المصدر: Science. 284:2184-2188
مصطلحات موضوعية: Receptors, Neuropeptide, medicine.medical_specialty, Colon, G protein, Motilin receptor, Molecular Sequence Data, Thyroid Gland, Gastric motility, Peptide hormone, Biology, Ligands, Transfection, Cell Line, Receptors, Gastrointestinal Hormone, Motilin, GTP-Binding Proteins, Internal medicine, Heterotrimeric G protein, Intestine, Small, medicine, Humans, Amino Acid Sequence, Cloning, Molecular, Receptor, Antrum, In Situ Hybridization, Binding Sites, Multidisciplinary, Base Sequence, Chromosomes, Human, Pair 13, digestive, oral, and skin physiology, Chromosome Mapping, Erythromycin, Alternative Splicing, Endocrinology, Gastric Mucosa, Calcium, hormones, hormone substitutes, and hormone antagonists
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8
المؤلفون: Dennis C. Dean, Donna L. Hreniuk, Karen K. McKee, Carina P. Tan, Ravi P. Nargund, Lht Van der Ploeg, JR Tata, Kristine Prendergast, Andrew D. Howard, Scott D. Feighner, Arthur A. Patchett, Oksana C. Palyha, JW Woods, Roy G. Smith, D Underwood
المصدر: Molecular Endocrinology. 12:137-145
مصطلحات موضوعية: Agonist, medicine.medical_specialty, Growth-hormone-releasing hormone receptor, Swine, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Molecular Sequence Data, Receptors, Cell Surface, Peptide, Biology, Non peptide, Receptors, G-Protein-Coupled, Endocrinology, GTP-Binding Proteins, Thyrotropin-releasing hormone receptor, Internal medicine, medicine, Animals, Humans, Amino Acid Sequence, Receptors, Ghrelin, Receptor, Molecular Biology, chemistry.chemical_classification, Human Growth Hormone, Human growth hormone, General Medicine, Ligand (biochemistry), Transmembrane protein, Rats, Transmembrane domain, Biochemistry, chemistry, Hormone receptor, Mutagenesis, Site-Directed, Secretagogue, Peptides, Binding domain
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d56a687a83b3f530fe4e6240d6ee0c
https://doi.org/10.1210/mend.12.1.0051 -
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المؤلفون: Donna L. Hreniuk, L. H. T. Van Der Ploeg, Scott D. Feighner, Roy G. Smith, Oksana C. Palyha, Karen K. McKee, Andrew D. Howard, Carina P. Tan, J. Liu
المصدر: Genomics. 46:426-434
مصطلحات موضوعية: Molecular Sequence Data, Growth hormone secretagogue receptor, Gene Expression, Receptors, Cell Surface, Biology, G Protein-Coupled Receptor Gene, Receptors, G-Protein-Coupled, Conserved sequence, Evolution, Molecular, Gene mapping, GTP-Binding Proteins, Growth hormone secretagogue, Genetics, Animals, Humans, Receptors, Neurotensin, Amino Acid Sequence, Cloning, Molecular, Receptors, Ghrelin, Gene, Peptide sequence, Conserved Sequence, Chromosomes, Human, Pair 13, Sequence Homology, Amino Acid, Nucleic acid sequence, Chromosome Mapping, Molecular biology, Chromosomes, Human, Pair 2, hormones, hormone substitutes, and hormone antagonists
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المصدر: Canadian Journal of Physiology and Pharmacology. 75:735-740
مصطلحات موضوعية: Pharmacology, Physiology, Stereochemistry, Chemistry, Physiology (medical), Bradykinin B1 Receptors, General Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd79554f415fdb537aaef58d26debe00
https://doi.org/10.1139/cjpp-75-6-735