نتائج البحث - "Dopaminergic Neurons metabolism"

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دورية أكاديمية

Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC.

المؤلفون: Palazzi, Luana, Fongaro, Benedetta, Leri, Manuela, Acquasaliente, Laura, Stefani, Massimo, Bucciantini, Monica, Polverino de Laureto, Patrizia

المصدر: International Journal of Molecular Sciences, 22 (11), 6008 (2021-06-02)

مصطلحات موضوعية: DOPAC, Parkinson’s disease, autophagy, fibril inhibition, oligomer toxicity, protein oligomerization, α-synuclein aggregation inhibition, Amyloid, SNCA protein, human, alpha-Synuclein, 3,4-Dihydroxyphenylacetic Acid, 3,4-dihydroxyphenylethanol, 3,4-dihydroxyphenylacetaldehyde, Phenylethyl Alcohol, Dopamine, 3,4-Dihydroxyphenylacetic Acid/analogs & derivatives, 3,4-Dihydroxyphenylacetic Acid/pharmacology, Amyloid/drug effects, Amyloid/genetics, Cell Proliferation/drug effects, Dopamine/genetics, Dopamine/metabolism, Dopaminergic Neurons/drug effects, Dopaminergic Neurons/metabolism, Dopaminergic Neurons/pathology, Humans, Oxidative Stress/drug effects, Parkinson Disease/drug therapy, Parkinson Disease/genetics, Parkinson Disease/metabolism, Parkinson Disease/pathology, Phenylethyl Alcohol/analogs & derivatives, Phenylethyl Alcohol/pharmacology, Protein Aggregation, Pathological/drug therapy, Protein Aggregation, Pathological/genetics, Protein Multimerization/genetics, alpha-Synuclein/antagonists & inhibitors, alpha-Synuclein/genetics, Cell Proliferation, Dopaminergic Neurons, Oxidative Stress, Protein Aggregation, Pathological, Protein Multimerization, Catalysis, Molecular Biology, Spectroscopy, Computer Science Applications, Physical and Theoretical Chemistry, Organic Chemistry, Inorganic Chemistry, General Medicine, Life sciences, Biotechnology, Biochemistry, biophysics & molecular biology, Human health sciences, Neurology, Sciences du vivant, Biotechnologie, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Neurologie

Relation: https://www.mdpi.com/1422-0067/22/11/6008/pdf; urn:issn:1661-6596; urn:issn:1422-0067

URL الوصول: https://orbi.uliege.be/handle/2268/295246

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Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition

المؤلفون: Laura Mahoney-Sanchez, Hind Bouchaoui, Ibrahim Boussaad, Aurélie Jonneaux, Kelly Timmerman, Olivier Berdeaux, Scott Ayton, Rejko Krüger, James A. Duce, David Devos, Jean-Christophe Devedjian

المساهمون: Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), University of Luxembourg [Luxembourg], Plateforme Chemosens [Dijon], Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), University of Melbourne, Julien, Sabine

المصدر: Cell Reports
Cell Reports, 2022, 40 (8), pp.111231. ⟨10.1016/j.celrep.2022.111231⟩

مصطلحات موضوعية: History, Molecular biology [CP], Polymers and Plastics, Neurology [D14] [Human health sciences], Parkinson's disease, ether phospholipids, Industrial and Manufacturing Engineering, General Biochemistry, Genetics and Molecular Biology, Dopaminergic Neurons/metabolism, alpha-Synuclein/metabolism, alpha synuclein, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Business and International Management, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Neurologie [D14] [Sciences de la santé humaine], Neuroscience [CP], Dopaminergic Neurons, Phospholipid Ethers, Parkinson Disease, lipid peroxidation, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Parkinson Disease/metabolism, ferroptosis, cell death, Phospholipid Ethers/metabolism, alpha-Synuclein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b27c4e302eadacc48ae4fca29821df5
https://hal.inrae.fr/hal-03813276/file/mahoney-sanchez_2022_vol40_111231_cell_rep.pdf

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A genome on shaky ground: exploring the impact of mitochondrial DNA integrity on Parkinson's disease by highlighting the use of cybrid models

المؤلفون: Peter P Pramstaller, Anne Grünewald, Andrew Hicks, Martin Lang, Irene Pichler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237b6dd659d06f6928631de97c47569f
http://orbilu.uni.lu/handle/10993/51045

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Dynamic dichotomy of accumbal population activity underlies cocaine sensitization

المؤلفون: Yue Li, Lucile Marion-Poll, Jérôme Flakowski, Ruud van Zessen, Christian Lüscher, Nicolas Hulo

المصدر: eLife, Vol. 10 (2021) P. e66048
eLife, Vol 10 (2021)
eLife

مصطلحات موضوعية: Male, Mouse, nucleus accumbens, Dopamine, Calcium imaging, 0302 clinical medicine, ddc:590, Cocaine, population coding, Biology (General), Sensitization, media_common, spiny projection neuron, 0303 health sciences, education.field_of_study, General Neuroscience, Locomotion / drug effects, General Medicine, calcium imaging, medicine.anatomical_structure, Population coding, Medicine, Nucleus accumbens, Female, dopamine, Locomotion, medicine.drug, Research Article, Receptors, Dopamine D1 / metabolism, Receptors, Dopamine D2 / metabolism, QH301-705.5, media_common.quotation_subject, Science, Population, cocaine, Mice, Transgenic, Biology, Medium spiny neuron, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Dopamine receptor D2, medicine, Animals, Nucleus Accumbens / metabolism, education, Cocaine / pharmacology, 030304 developmental biology, General Immunology and Microbiology, Receptors, Dopamine D2, Dopaminergic Neurons / metabolism, Addiction, Dopaminergic Neurons, Receptors, Dopamine D1, Spiny projection neuron, ddc:616.8, Dopaminergic Neurons / drug effects, Mice, Inbred C57BL, Nucleus Accumbens / drug effects, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb8483a5701a516c1c25af226be4a26
https://archive-ouverte.unige.ch/unige:158151

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5

Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson��s Disease

المؤلفون: Stefanie Seiler, Lukas Andereggen, Hans Rudolf Widmer, Ekkehard Hewer, Gian-Carlo Eyer, Stefano Di Santo

المصدر: Eyer, Gian-Carlo; Di Santo, Stefano; Hewer, Ekkehard; Andereggen, Lukas; Seiler, Stefanie; Widmer, Hans Rudolf (2021). Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson’s Disease. Cells, 10(12) MDPI 10.3390/cells10123368 <http://dx.doi.org/10.3390/cells10123368>
Cells, Vol 10, Iss 3368, p 3368 (2021)
Cells
Cells; Volume 10; Issue 12; Pages: 3368
Cells, vol. 10, no. 12, pp. 3368

مصطلحات موضوعية: Male, Aging, Parkinson's disease, Tyrosine 3-Monooxygenase, QH301-705.5, Nogo Proteins, Cell Count, Substantia nigra, 610 Medicine & health, Disease, Normal aging, Biology, Article, Age Factors, Aged, Aged, 80 and over, Aging/metabolism, Dopaminergic Neurons/metabolism, Humans, Nogo Proteins/metabolism, Parkinson Disease/metabolism, Substantia Nigra/metabolism, Tyrosine 3-Monooxygenase/metabolism, Nogo-A, Parkinson’s disease, human, immunofluorescence, substantia nigra pars compacta, tyrosine hydroxylase, mental disorders, medicine, Biology (General), Tyrosine hydroxylase, Pars compacta, Dopaminergic Neurons, Dopaminergic, Neurodegeneration, Parkinson Disease, General Medicine, medicine.disease, nervous system diseases, Substantia Nigra, nervous system, 570 Life sciences, biology, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1658244281552db14bd32eb1a1c5138

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A Subpopulation of Dopaminergic Neurons Coexpresses Serotonin in Ventral Mesencephalic Cultures but not after Intrastriatal Transplantation in a Rat Model of Parkinson's Disease

المؤلفون: Hans Rudolf Widmer, Stefanie Seiler, Angélique Ducray, Morten Meyer, Stefano Di Santo

المصدر: Di Santo, S, Seiler, S, Ducray, A, Meyer, M & Widmer, H 2017, ' A subpopulation of dopaminergic neurons co-expresses serotonin in ventral mesencephalic cultures but not after intrastriatal transplantation in a rat model of Parkinsons disease ', Cell Transplantation, vol. 26, no. 4, pp. 679-691 . https://doi.org/10.3727/096368916X693707
Cell Transplantation, Vol 26 (2017)

مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Cell Count, 5-Hydroxytryptamine (5HT), Serotonin/metabolism, 0302 clinical medicine, Mesencephalon, Parkinsonian rats, Neurotrophic factors, gamma-Aminobutyric Acid/metabolism, gamma-Aminobutyric Acid, Cells, Cultured, 630 Agriculture, Dopaminergic, Parkinson Disease, Parkinson Disease/metabolism, Female, Human, Serotonin, Tyrosine 3-Monooxygenase/metabolism, medicine.medical_specialty, Tyrosine 3-Monooxygenase, Biomedical Engineering, Brain-Derived Neurotrophic Factor/pharmacology, Biology, Article, Dopaminergic Neurons/metabolism, 03 medical and health sciences, Neuroblast, Internal medicine, Neurosphere, medicine, Humans, Animals, Rats, Wistar, Brain-derived neurotrophic factor, Transplantation, Brain-Derived Neurotrophic Factor, Dopaminergic Neurons, lcsh:R, Colocalization, Cell Biology, Tyrosine hydroxylase (TH), Disease Models, Animal, 030104 developmental biology, Endocrinology, nervous system, 570 Life sciences, biology, Cell transplantation, Mesencephalon/drug effects, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3743ef3e0bed6bc34a41d9230bde341
https://doi.org/10.3727/096368916x693707

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7

Testosterone boosts physical activity in male mice via dopaminergic pathways

المؤلفون: Brigitte Decallonne, Geert Carmeliet, Lawrence Van Helleputte, Ludo Deboel, Ann Van Eeckhaut, Michaël R. Laurent, Dieter Schollaert, Dirk Vanderschueren, Nari Kim, Rudi D'Hooge, Dimitri De Bundel, Rougin Khalil, Ferran Jardi, Ludo Van Den Bosch, Frank Claessens, Vanessa Dubois

المساهمون: Pharmaceutical and Pharmacological Sciences, Experimental Pharmacology

المصدر: SCIENTIFIC REPORTS
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Dopamine, OLDER MEN, INACTIVITY, DORSAL STRIATUM, Receptors, Androgen/metabolism, lcsh:Medicine, Running, 0302 clinical medicine, Sex hormone-binding globulin, Physical Conditioning, Animal/physiology, Medicine and Health Sciences, Testosterone, Orchiectomy/methods, Orchiectomy, lcsh:Science, GENE-EXPRESSION, Multidisciplinary, biology, Chemistry, LOCOMOTION, Motor Activity/physiology, Running/physiology, medicine.anatomical_structure, Receptors, Androgen, Dopaminergic pathways, Testosterone/metabolism, Androgens, medicine.drug, medicine.medical_specialty, mice, SEX-DIFFERENCES, Mice, Transgenic, Motor Activity, Article, Dopaminergic Neurons/metabolism, 03 medical and health sciences, ANDROGENS, Physical Conditioning, Animal, Internal medicine, Androgens/metabolism, Androgen deficiency, medicine, Animals, RECEPTOR, Dopaminergic Neurons, lcsh:R, medicine.disease, Dopamine/metabolism, Mice, Inbred C57BL, Androgen receptor, 030104 developmental biology, Endocrinology, KNOCKOUT, Free fraction, GONADECTOMY, Mice, Transgenic/metabolism, biology.protein, lcsh:Q, 030217 neurology & neurosurgery

وصف الملف: Electronic; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473681375428eb8f149a9d6d42fdb8d0
https://lirias.kuleuven.be/handle/123456789/617408

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SHANK3 controls maturation of social reward circuits in the VTA

المؤلفون: Luca Pucci, François Georges, Joanna Viguie, Camilla Bellone, Christelle Glangetas, Christian Lüscher, Paola Bezzi, Sebastiano Bariselli, Eoin C. O'Connor, Clément Prévost-Solié, Stamatina Tzanoulinou

المساهمون: Institut des Maladies Neurodégénératives [Bordeaux] (IMN), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Université de Lausanne (UNIL), Interdisciplinary Institute for Neuroscience (IINS), Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB), Università degli studi di Napoli Federico II, Bionext, Dauphine Recherches en Management (DRM), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Neurodegeneratives Diseases Institute (IMN-UMR CNRS 5293), Centre National de la Recherche Scientifique (CNRS)

المصدر: Nature Neuroscience, Vol. 19, No 7 (2016) pp. 926-934
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2016, 19 (7), pp.926-934. ⟨10.1038/nn.4319⟩
nature neuroscience
Nature neuroscience
Nature neuroscience, vol. 19, no. 7, pp. 926-934

مصطلحات موضوعية: Animals, Autism Spectrum Disorder/metabolism, Behavior, Animal/physiology, Dopamine/metabolism, Dopaminergic Neurons/metabolism, GABAergic Neurons/drug effects, Hippocampus/metabolism, Inhibitory Postsynaptic Potentials/drug effects, Mice, Inbred C57BL, Mice, Transgenic, Nerve Tissue Proteins/metabolism, Patch-Clamp Techniques/methods, Reward, Synapses/metabolism, Synaptic Transmission/physiology, Ventral Tegmental Area/metabolism, 0301 basic medicine, Patch-Clamp Techniques, Autism Spectrum Disorder, [SDV]Life Sciences [q-bio], Dopamine, Nerve Tissue Proteins, Neurotransmission, Hippocampus, Synaptic Transmission, Synapse, 03 medical and health sciences, 0302 clinical medicine, Excitatory synapse, medicine, Biological neural network, animals, autism spectrum disorder, behavior, animal, dopamine, dopaminergic neurons, gabaergic neurons, hippocampus, inhibitory postsynaptic potentials, mice, inbred c57bl, mice, transgenic, nerve tissue proteins, patch-clamp techniques, synapses, synaptic transmission, ventral tegmental area, reward, GABAergic Neurons, ComputingMilieux_MISCELLANEOUS, Behavior, Animal, General Neuroscience, Dopaminergic Neurons, Microfilament Proteins, Ventral Tegmental Area, ddc:616.8, Ventral tegmental area, 030104 developmental biology, medicine.anatomical_structure, Inhibitory Postsynaptic Potentials, Metabotropic glutamate receptor, Synapses, Metabotropic glutamate receptor 1, Neuron, Psychology, Neuroscience, 030217 neurology & neurosurgery