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المؤلفون: Palucki Brenda, Patrick G. Pollard, Liangqin Guo, Tung M. Fong, Matthew J. Wyvratt, Randy R. Miller, Shuwen He, Constantin Tamvakopoulos, Iyassu K. Sebhat, Qianping Peng, Ravi P. Nargund, Zhixiong Ye, Airu S. Chen, Doreen E. Cashen, David H. Weinberg, Min K. Park, Raman K. Bakshi, D. Euan MacIntyre, Howard Y. Chen, Rui Tang, Tanya MacNeil, Qingmei Hong, Alison M. Strack, Ralph A. Stearns, Jian Liu, William J. Martin
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:2330-2334
مصطلحات موضوعية: medicine.drug_class, Clinical Biochemistry, Drug Evaluation, Preclinical, Administration, Oral, Biological Availability, Pharmaceutical Science, Carboxamide, Pharmacology, Biochemistry, Partial agonist, Piperazines, Rats, Sprague-Dawley, Eating, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Oral administration, In vivo, Drug Discovery, medicine, Animals, Urea, Obesity, Receptor, Molecular Biology, Organic Chemistry, Haplorhini, Rats, Disease Models, Animal, Piperazine, chemistry, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin
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2
المؤلفون: Howard Y. Chen, William J. Martin, D. Euan MacIntyre, Zhixiong Ye, Raman K. Bakshi, Alison M. Strack, Doreen E. Cashen, Jian Liu, Yingjie Lai, Tianying Jian, Constantin Tamvakopoulos, Nancy N. Tsou, Shuwen He, James Dellureficio, Tung M. Fong, Peter H. Dobbelaar, David H. Weinberg, Airu S. Chen, Qingmei Hong, Iyassu K. Sebhat, Tanya MacNeil, Christopher L. Franklin, Ravi P. Nargund, Ralph A. Stearns, Rui Tang, Richard G. Ball, Matthew J. Wyvratt, Randy R. Miller, Liangqin Guo, Qianping Peng
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2106-2110
مصطلحات موضوعية: Male, Agonist, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, CHO Cells, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, Cricetulus, Dogs, Erectile Dysfunction, Cricetinae, Drug Discovery, medicine, Animals, Humans, Spiro Compounds, Receptor, Molecular Biology, Molecular Structure, Chemistry, Organic Chemistry, Haplorhini, Rats, Bioavailability, Indans, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin, Protein Binding
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3
المؤلفون: Matthew J. Wyvratt, Vivien A. Warren, John P. Felix, Maria L. Garcia, Scott B. Hoyt, William H. Parsons, Kathryn A. Lyons, Xiaohua Li, Michael H. Fisher, Clare London, McHardy M. Smith, Birgit T. Priest, Gregory J. Kaczorowski, Doreen E. Cashen, William J. Martin, D. Euan MacIntyre, Brande S. Williams
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:1963-1966
مصطلحات موضوعية: medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Mice, Epilepsy, Sodium channel blocker, Drug Discovery, Fluorescence Resonance Energy Transfer, medicine, Animals, Humans, Molecular Biology, Membrane potential, Benzodiazepinones, Electroshock, Molecular Structure, Chemistry, Sodium channel, Organic Chemistry, Biological activity, medicine.disease, Ether-A-Go-Go Potassium Channels, Rats, Electrophysiology, Anticonvulsant, Molecular Medicine, Anticonvulsants, Sodium Channel Blockers
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المؤلفون: Doreen E. Cashen, Constantin Tamvakopoulos, Qianping Peng, William J. Martin, David H. Weinberg, Charles Rosenblum, Arthur A. Patchett, Tanya MacNeil, Patrick G. Pollard, Zhixiong Ye, Raman K. Bakshi, Ralph A. Stearns, Rubana N. Kalyani, Palucki Brenda, Joseph M. Metzger, Alison M. Strack, Lex H.T. Van der Ploeg, D. Euan MacIntyre, Iyassu K. Sebhat, Aurawan Vongs, Airu S. Chen, Ravi P. Nargund, Liangqin Guo, Matthew J. Wyvratt, Randy R. Miller, Rui Tang, Howard Y. Chen, Khaled J. Barakat
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:3501-3505
مصطلحات موضوعية: Male, Agonist, Quinuclidines, Time Factors, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Rodentia, Carboxamide, Biochemistry, Chemical synthesis, Piperazines, Rats, Sprague-Dawley, Eating, Structure-Activity Relationship, Piperidines, In vivo, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Aza Compounds, Bicyclic molecule, Chemistry, Penile Erection, digestive, oral, and skin physiology, Organic Chemistry, Small molecule, Rats, Microsomes, Liver, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin, Protein Binding
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المؤلفون: Doreen E. Cashen, Erin McGowan, Jennifer E. Drisko, Ravi P. Nargund, William J. Martin, D. Euan MacIntyre, Gary J Hom, Iyassu K. Sebhat, Lex H.T. Van der Ploeg, Liza Gantert, Andrew D. Howard
المصدر: European Journal of Pharmacology. 454:71-79
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, medicine.drug_class, Binding, Competitive, Peptides, Cyclic, Piperazines, Rats, Sprague-Dawley, Tetrahydroisoquinolines, Internal medicine, medicine, Animals, Agouti-Related Protein, ACTH receptor, Receptor, Pharmacology, Camphanes, Dose-Response Relationship, Drug, Chemistry, Penile Erection, digestive, oral, and skin physiology, Antagonist, Triazoles, Isoquinolines, Receptor antagonist, Peptide Fragments, Rats, Apomorphine, Endocrinology, Receptors, Corticotropin, THIQ, Receptor, Melanocortin, Type 4, Melanocortin, hormones, hormone substitutes, and hormone antagonists, medicine.drug
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المؤلفون: Ralph A. Stearns, Randy R. Miller, William J. Martin, Ravi P. Nargund, Erin McGowan, Lex H.T. Van der Ploeg, and Arthur A. Patchett, Andrew D. Howard, David B. R. Johnston, D. Euan MacIntyre, Rubana N. Kalyani, Khaled Barakat, Raman K. Bakshi, Ralph T. Mosley, Jennifer E. Drisko, Constantin Tamvakopoulos, Rui Tang, Alison M. Strack, Zhixiong Ye, Doreen E. Cashen, Tanya MacNeil, David H. Weinberg, Palucki Brenda, Gary J Hom, Iyassu K. Sebhat
المصدر: Journal of Medicinal Chemistry. 45:4589-4593
مصطلحات موضوعية: Agonist, Chemistry, medicine.drug_class, Biological activity, Pharmacology, Melanocortin receptor, THIQ, Drug Discovery, medicine, Anorectic, Molecular Medicine, Structure–activity relationship, Melanocortin, Receptor, medicine.drug
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المؤلفون: Christopher P. Austin, Doreen E. Cashen, Sheng-Shung Pong, Brian D. Spar, Brett Connolly, Tung Ming Fong, D. Euan MacIntyre, Carina P. Tan, Michael R. Tota, Ravi P. Nargund, R. S. L. Chang, Oksana C. Palyha, Constantin Tamvakopoulos, Deborah L. Drazen, Anthony G. DiLella, Jennifer E. Drisko, David J. Figueroa, Tanya MacNeil, Andreas W. Sailer, David H. Weinberg, Randy J. Nelson, Charles Rosenblum, Cathy R.-R.C. Huang, Rui Tang, Arthur A. Patchett, Xiao-Ming Guan, Hong Yu, George J. Christ, Andrew D. Howard, Lex H.T. Van der Ploeg, William J. Martin, Aurawan Vongs, Iyassu K. Sebhat, Ralph A. Stearns
المصدر: Proceedings of the National Academy of Sciences. 99:11381-11386
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, DNA, Complementary, Intracranial Pressure, medicine.drug_class, Blood Pressure, In Vitro Techniques, Biology, Somatosensory system, Mice, Sexual Behavior, Animal, Nerve Fibers, Internal medicine, Copulation, medicine, Animals, Glans, In Situ Hybridization, DNA Primers, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, Human penis, Feeding Behavior, Ribonuclease, Pancreatic, Biological Sciences, Spinal cord, Electric Stimulation, Mice, Inbred C57BL, Melanocortin 4 receptor, medicine.anatomical_structure, Endocrinology, Receptors, Corticotropin, Models, Animal, Receptor, Melanocortin, Type 4, Brainstem, Energy Metabolism, Penis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341db11f0e12a0307d07e04176cd4aad
https://doi.org/10.1073/pnas.172378699 -
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المؤلفون: D. Euan MacIntyre, Doreen E. Cashen, William J. Martin
المصدر: British Journal of Pharmacology. 136:693-700
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Mean arterial pressure, Sildenafil, Nitric Oxide Synthase Type III, Stimulation, Biology, biology.organism_classification, medicine.disease, Nitric oxide synthase, chemistry.chemical_compound, Endocrinology, Erectile dysfunction, chemistry, Enos, In vivo, Internal medicine, cardiovascular system, biology.protein, medicine
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المؤلفون: Lex H.T. Van der Ploeg, James Dellureficio, Peter H. Dobbelaar, Rui Tang, Airu S. Chen, Shuwen He, Liangqin Guo, Doreen E. Cashen, Joseph M. Metzger, Qingping Peng, Charles Rosenblum, Zhixiong Ye, Tanya MacNeil, Constantin Tamvakopoulos, David H. Weinberg, Qingmei Hong, Ravi P. Nargund, Matthew J. Wyvratt, Allison M. Strack, Euan Maclntyre, Randy R. Miller, Tung M. Fong, Raman K. Bakshi, Ralph A. Stearns, Rubana N. Kalyani, Jian Liu, Tianying Jian, Howard Y. Chen, Aurawan Vongs, Iyassu K. Sebhat, Willian J. Martin
المصدر: Bioorganicmedicinal chemistry letters. 20(15)
مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Ligands, Biochemistry, Chemical synthesis, Piperazines, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Piperazine, Organic Chemistry, Rats, chemistry, Benzene derivatives, Molecular Medicine, Receptor, Melanocortin, Type 4, Melanocortin
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المؤلفون: Mathias Z. Strowski, James M. Schaeffer, Thomas M. Jacks, Doreen E. Cashen, Roy G. Smith, Susan P. Rohrer, Arthur A. Patchett, Elizabeth T. Birzin, Vandana Singh, Krzysztof W. Nowak, Lihu Yang
المصدر: Endocrinology. 147(10)
مصطلحات موضوعية: Agonist, Blood Glucose, Male, endocrine system, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Mice, Obese, In Vitro Techniques, Glucagon, Islets of Langerhans, Mice, Endocrinology, Dogs, Internal medicine, Medicine, Animals, Hypoglycemic Agents, Insulin, Receptors, Somatostatin, Mice, Knockout, business.industry, Somatostatin receptor, Pancreatic islets, Glucagon secretion, Rats, Mice, Inbred C57BL, Somatostatin, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Growth Hormone, business, Glucagon receptor family, hormones, hormone substitutes, and hormone antagonists
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e95309c63dcec9bfdd3276bf547f1ec
https://pubmed.ncbi.nlm.nih.gov/16857751
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