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1دورية أكاديمية
المؤلفون: Douglas J MacNeil
المصدر: Frontiers in Endocrinology, Vol 4 (2013)
مصطلحات موضوعية: Obesity, Peptides, antagonist, Neuropeptide, clinical study, MCH, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Hua Zhong, John Beaulaurier, Pek Yee Lum, Cliona Molony, Xia Yang, Douglas J Macneil, Drew T Weingarth, Bin Zhang, Danielle Greenawalt, Radu Dobrin, Ke Hao, Sangsoon Woo, Christine Fabre-Suver, Su Qian, Michael R Tota, Mark P Keller, Christina M Kendziorski, Brian S Yandell, Victor Castro, Alan D Attie, Lee M Kaplan, Eric E Schadt
المصدر: PLoS Genetics, Vol 6, Iss 5, p e1000932 (2010)
وصف الملف: electronic resource
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3
المؤلفون: Joe Clemas, Jerry Andrew Taylor, Feroze Ujjainwalla, Jim Tata, Doris F. Cully, Tom Wisniewski, Wei Tang, Charlene Bopp, Clare London, Andreas Verras, Scott B. Hoyt, Andrea Sok, Elaine Tung, Douglas J. MacNeil, Gaochao Zhou, Amjad Ali, Qing Chen, Gino Salituro, Yusheng Xiong, Daniel R. McMasters, Mary Struthers, Ning Ren, Ruth A. Duffy
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2384-2388
مصطلحات موضوعية: Male, 0301 basic medicine, Aldosterone synthase, Indazoles, Clinical Biochemistry, High selectivity, Pharmaceutical Science, Pharmacology, 01 natural sciences, Biochemistry, Cell Line, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, Pharmacokinetics, Cytochrome P-450 CYP2D6 Inhibitors, Drug Discovery, Animals, Cytochrome P-450 CYP11B2, Humans, Molecular Biology, Antihypertensive Agents, Indazole, biology, Aromatase Inhibitors, Chemistry, Organic Chemistry, Stereoisomerism, Hit to lead, Macaca mulatta, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Hypertension, biology.protein, Steroid 11-beta-Hydroxylase, Molecular Medicine
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4
المؤلفون: Brent R. Whitehead, Michael M.-C. Lo, Amjad Ali, Min K. Park, Scott B. Hoyt, Yusheng Xiong, Jiaqiang Cai, Emma Carswell, Andrew Cooke, John MacLean, Paul Ratcliffe, John Robinson, D. Jonathan Bennett, Joseph A. Clemas, Tom Wisniewski, Mary Struthers, Doris Cully, Douglas J. MacNeil
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:143-146
مصطلحات موضوعية: Male, Aldosterone synthase, medicine.medical_specialty, Pyridines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Cricetulus, Internal medicine, Drug Discovery, medicine, Animals, Cytochrome P-450 CYP11B2, Humans, Rats, Wistar, Molecular Biology, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Imidazoles, Macaca mulatta, humanities, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Endocrinology, Microsomes, Liver, biology.protein, Steroid 11-beta-Hydroxylase, Molecular Medicine
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5
المؤلفون: Feroze Ujjainwalla, Charlene Bopp, Carrie Ann Shipley, Yusheng Xiong, Mary Struthers, Bindhu V. Karanam, Clare London, Gaochao Zhou, Ning Ren, Andreas Verras, Andrea Sok, Amjad Ali, Qing Chen, Doris F. Cully, Joseph Clemas, Jack Gibson, James R. Tata, Daniel R. McMasters, Ying Li, Whitney Lane Petrilli, Scott B. Hoyt, Elaine Tung, Ian Knemeyer, Ruth A. Duffy, Wei Tang, Thomas Wisniewski, Douglas J. MacNeil, Gino Salituro
المصدر: ACS medicinal chemistry letters. 8(1)
مصطلحات موضوعية: 0301 basic medicine, Aldosterone synthase, biology, Chemistry, Organic Chemistry, Resistant hypertension, Pharmacology, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Pharmacokinetics, Drug Discovery, biology.protein, Cyp enzymes, Piperidine
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6
المؤلفون: Marc L. Reitman, Ann E. Weber, Douglas J. MacNeil, Alison M. Strack, Liping Wang, Drew T. Weingarth, Jie Pan, Susan J. Lee, Scott D. Edmondson, Su Qian, James Hubert
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:2911-2915
مصطلحات موضوعية: Agonist, Pyrimidine, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Heterocyclic Compounds, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Receptor, Molecular Biology, Cells, Cultured, Cholecystokinin, Molecular Structure, Bicyclic molecule, Chemistry, Organic Chemistry, Amides, Receptor, Cholecystokinin A, Pyrimidines, Molecular Medicine, Protein Binding
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7
المؤلفون: Nermin Sumru Bayin, Joshua Frenster, J. Robert Kane, Aram Modrek, Nadim Shohdy, Douglas J. MacNeil, David Zagzag, Dimitris G. Placantonakis
المصدر: Neurosurgery. 63:158-159
مصطلحات موضوعية: Surgery, Neurology (clinical)
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8
المؤلفون: H Matsushita, Makoto Ito, H Iwaasa, Akio Kanatani, Masahiko Ito, Akane Ishihara, Joseph M. Metzger, Donald J. Marsh, Akira Gomori, Yuji Haga, M Moriya, S Tokita, N Takenaga, Nagaaki Sato, Douglas J. MacNeil
المصدر: British Journal of Pharmacology. 159:374-383
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Lateral hypothalamus, medicine.drug_class, Antagonist, Biology, Receptor antagonist, Endocrinology, Mechanism of action, Hormone receptor, Internal medicine, Orexigenic, medicine, medicine.symptom, Receptor, Thermogenesis, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::57ca982cfee114cae2a44d78ff4fd97c
https://doi.org/10.1111/j .1476-5381.2009.00536.x -
9
المؤلفون: Margarete Mehrabian, Sana Majid, Aldons J. Lusis, Tao Xie, Pek Yee Lum, Daria Estrada-Smith, Lawrence W. Castellani, Thomas A. Drake, Robert R. Kleinhanz, Anatole Ghazalpour, Gevork Torosyan, Jun Zhu, Joshua L. Deignan, Eric E. Schadt, Su Qian, Kai Wang, Katrina M. Dipple, Jenny C Karlsson, Douglas J. MacNeil, Xia Yang, Judy Zhong, Charles R. Farber, Marc L. Reitman, Bin Zhang, Michael Coon, Chunsheng Zhang, Susanna S. Wang, John Lamb, Hongxiu Qi, Sheena Mumick, Atila van Nas, Brie Falkard
المصدر: Nature genetics, vol 41, iss 4
مصطلحات موضوعية: Male, Candidate gene, Vesicular Transport Proteins, Metabolic network, Cardiovascular, Medical and Health Sciences, Transgenic, Oral and gastrointestinal, Mice, 0302 clinical medicine, Abdomen, 2.1 Biological and endogenous factors, Aetiology, Abdominal obesity, Cancer, Genetics, 0303 health sciences, Skeletal, Biological Sciences, Phenotype, Stroke, Liver, Adipose Tissue, Knockout mouse, Muscle, Female, medicine.symptom, Transcription, Knockout, Nerve Tissue Proteins, Biology, 03 medical and health sciences, Genetic, Genetic variation, medicine, Animals, Humans, Obesity, Gene, Metabolic and endocrine, Glycoproteins, Nutrition, 030304 developmental biology, Glutathione Peroxidase, Animal, Gene Expression Profiling, Reproducibility of Results, Genetic Variation, Gene expression profiling, Disease Models, Carrier Proteins, 030217 neurology & neurosurgery, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Michael R. Tota, Su Qian, Peter Nizner, Sheena Mumick, Joseph Menetski, Marc L. Reitman, Douglas J. MacNeil
المصدر: Basic & Clinical Pharmacology & Toxicology. 103:36-42
مصطلحات موضوعية: Male, medicine.medical_specialty, Genotype, Glutathione reductase, Malic enzyme, Biology, Toxicology, Malate dehydrogenase, Mice, chemistry.chemical_compound, Cytosol, Malate Dehydrogenase, Internal medicine, medicine, Animals, Glycolysis, Acetaminophen, Pharmacology, Liver injury, Analgesics, General Medicine, Glutathione, medicine.disease, Mice, Mutant Strains, Mice, Inbred C57BL, Citric acid cycle, Endocrinology, Liver, Biochemistry, chemistry, Chemical and Drug Induced Liver Injury, NADP, Nicotinamide adenine dinucleotide phosphate
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1e0d9a14399ca5b91a7072761b7b93
https://doi.org/10.1111/j .1742-7843.2008.00228.x