يعرض 1 - 4 نتائج من 4 نتيجة بحث عن '"Douglas M. Roberts"', وقت الاستعلام: 0.88s تنقيح النتائج
  1. 1
    Diene incorporation by a dehydratase domain variant in modular polyketide synthases

    المؤلفون: Christian Hobson, Matthew Jenner, Xinyun Jian, Daniel Griffiths, Douglas M. Roberts, Matias Rey-Carrizo, Gregory L. Challis

    المصدر: Nature chemical biology. 18(12)

    مصطلحات موضوعية: Polyketides, Water, Cell Biology, Polyenes, Molecular Biology, Polyketide Synthases, Hydro-Lyases, Carbon, Substrate Specificity

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de37ed0f0cb959136c772400f974dddf
    https://pubmed.ncbi.nlm.nih.gov/36109649

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  2. 2
    A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis

    المؤلفون: Rhiannon Howe, Christian Hobson, Julian Parkhill, Zhong Ling Yap, Eshwar Mahenthiralingam, Cerith Jones, Joleen Masschelein, Douglas M. Roberts, Paulina K. Sydor, Gregory L. Challis

    المساهمون: Masschelein, Joleen [0000-0003-4366-3675], Jones, Cerith [0000-0001-6275-0235], Parkhill, Julian [0000-0002-7069-5958], Mahenthiralingam, Eshwar [0000-0001-9014-3790], Challis, Gregory L [0000-0001-5976-3545], Apollo - University of Cambridge Repository

    المصدر: Nature chemistry

    مصطلحات موضوعية: Acinetobacter baumannii, Stereochemistry, Acylation, General Chemical Engineering, Chemistry, Multidisciplinary, Microbial Sensitivity Tests, Polyenes, 010402 general chemistry, Thioester, 01 natural sciences, Article, Condensation domain, chemistry.chemical_compound, Polyketide, Transacylation, Biosynthesis, Polyketide synthase, LOGIC, IIA, chemistry.chemical_classification, Science & Technology, Molecular Structure, biology, 010405 organic chemistry, Chemistry, ELONGATION-FACTOR TU, General Chemistry, QP, Anti-Bacterial Agents, 0104 chemical sciences, Acyl carrier protein, BOND FORMATION, KETOSYNTHASE, Physical Sciences, biology.protein, Polyketide Synthases

    وصف الملف: Print-Electronic; application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d0a8a648f5dc0f167122c7a9f7afdf
    https://lirias.kuleuven.be/handle/123456789/642742

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  3. 3
    An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’ icosalide antibiotics

    المؤلفون: Cerith Jones, Joleen Masschelein, Xinyun Jian, Cedric J. Pearce, Gregory L. Challis, Yousef Dashti, Eshwar Mahenthiralingam, Simon R. Harris, Julian Parkhill, Matthew Jenner, Christian Hobson, Nicholas H. Oberlies, Douglas M. Roberts, Huzefa A. Raja

    المساهمون: Jenner, Matthew [0000-0003-2317-3011], Dashti, Yousef [0000-0002-8490-7763], Masschelein, Joleen [0000-0003-4366-3675], Jones, Cerith [0000-0001-6275-0235], Harris, Simon [0000-0003-1512-6194], Parkhill, Julian [0000-0002-7069-5958], Raja, Huzefa A [0000-0002-0824-9463], Oberlies, Nicholas H [0000-0002-0354-8464], Mahenthiralingam, Eshwar [0000-0001-9014-3790], Challis, Gregory L [0000-0001-5976-3545], Apollo - University of Cambridge Repository

    مصطلحات موضوعية: Burkholderia gladioli, Sequence analysis, FOS: Health sciences, 010402 general chemistry, 01 natural sciences, Condensation domain, chemistry.chemical_compound, Nonribosomal peptide, Genetics, Gene, chemistry.chemical_classification, biology, 34 Chemical Sciences, 010405 organic chemistry, Lipopeptide, General Chemistry, biology.organism_classification, 0104 chemical sciences, Burkholderia, Infectious Diseases, Emerging Infectious Diseases, chemistry, Biochemistry, FOS: Biological sciences, Infection, DNA, Biotechnology

    وصف الملف: application/pdf; Electronic-eCollection

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b5e652eb45f898ed27ae53fca92387
    http://wrap.warwick.ac.uk/116476/20/WRAP-unusual-Burkholderia-gladioli-double-chain-initiating-nonribosomal-peptide-synthetase-Challis-2019.pdf

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  4. 4
    A Flavin-Dependent Decarboxylase-Dehydrogenase-Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors

    المؤلفون: Peter F. Leadlay, Daniel Zabala, Jason Micklefield, Brian J. C. Law, Lijiang Song, Gregory L. Challis, Markiyan Samborskyy, Douglas M. Roberts, Joshua W. Cartwright

    المصدر: Journal of the American Chemical Society. 138(13)

    مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Cytochrome, Carboxy-Lyases, Dinitrocresols, Dehydrogenase, Flavin group, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, Colloid and Surface Chemistry, Methionine, Biosynthesis, Cytochrome P-450 Enzyme System, Flavins, medicine, chemistry.chemical_classification, biology, Stereoisomerism, General Chemistry, Dipeptides, Monooxygenase, Streptomyces, 0104 chemical sciences, 030104 developmental biology, Enzyme, chemistry, Proteasome inhibitor, biology.protein, Proteasome Inhibitors, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9edd738cdd5ff4f0e2a78b0bc16049
    https://pubmed.ncbi.nlm.nih.gov/26999044

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