المؤلفون: Feng Y; State Key Laboratory of Photon-Technology in Western China Energy, Institute of Photonics and Photon-Technology, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China., Che B; School of Physics, Northwest University, No. 1 Xuefu Avenue, Xi'an 710127, Shaanxi, China., Fu J; State Key Laboratory of Photon-Technology in Western China Energy, Institute of Photonics and Photon-Technology, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China., Sun Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710127, China., Ma W; State Key Laboratory of Photon-Technology in Western China Energy, Institute of Photonics and Photon-Technology, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China., Tian J; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710127, China.; Center for Automated and Innovative Drug Discovery, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China., Dai L; Department of Physics, City University of Hong Kong, Hong Kong 999077, China., Jing G; School of Physics, Northwest University, No. 1 Xuefu Avenue, Xi'an 710127, Shaanxi, China., Zhao W; State Key Laboratory of Photon-Technology in Western China Energy, Institute of Photonics and Photon-Technology, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China., Sun D; State Key Laboratory of Photon-Technology in Western China Energy, Institute of Photonics and Photon-Technology, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China.; Center for Automated and Innovative Drug Discovery, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China., Zhang C; State Key Laboratory of Photon-Technology in Western China Energy, Institute of Photonics and Photon-Technology, Northwest University, No. 1, Xuefu Avenue, Xi'an 710127, Shaanxi, China.

المصدر: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2024 Aug 12; Vol. 10 (8), pp. 5399-5408. Date of Electronic Publication: 2024 Jul 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101654670 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-9878 (Electronic) Linking ISSN: 23739878 NLM ISO Abbreviation: ACS Biomater Sci Eng Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Screening Assays*/methods , High-Throughput Screening Assays*/instrumentation , Lab-On-A-Chip Devices* , Drug Evaluation, Preclinical*/methods , Drug Evaluation, Preclinical*/instrumentation, Humans ; Point-of-Care Systems ; Cell Culture Techniques/instrumentation ; Cell Culture Techniques/methods ; Animals ; Dimethylpolysiloxanes/chemistry ; Microfluidic Analytical Techniques/instrumentation ; Microfluidic Analytical Techniques/methods

المؤلفون: Hodges D; CBSET, MA, USA., Stonerook M; AmplifyBio, OH, USA., Salvail D; IPST, QC, Canada., Lemouton S; Emka TECHNOLOGIES, Paris, France. Electronic address: sl@emka.fr.

المصدر: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Jul-Aug; Vol. 128, pp. 107538. Date of Electronic Publication: 2024 Jun 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical*/methods , Drug Evaluation, Preclinical*/economics, Animals ; Humans ; Swine ; Dogs ; Drug Development/methods ; Drug Development/economics ; Toxicity Tests/methods ; Toxicity Tests/economics ; Animal Testing Alternatives/methods ; Animal Testing Alternatives/economics ; Drug-Related Side Effects and Adverse Reactions

المؤلفون: Sari IP; Institute of Molecular Medicine, College of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan.; Department of Bioscience Technology, Chung Yuan Christian University, Chung-Li, Taoyuan City 320314, Taiwan., Ortiz CLD; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Institute of Biological Chemistry, Academia Sinica, 128 Academia Road, Section 2, Taipei 11529, Taiwan.; Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.; Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan., Yang LW; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Institute of Biological Chemistry, Academia Sinica, 128 Academia Road, Section 2, Taipei 11529, Taiwan.; Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan., Chen MH; Institute of Molecular Medicine, College of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan., Perng MD; Institute of Molecular Medicine, College of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan., Wu TY; Department of Bioscience Technology, Chung Yuan Christian University, Chung-Li, Taoyuan City 320314, Taiwan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 22; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Nipah Virus*/genetics , Nipah Virus*/drug effects , Baculoviridae*/genetics , Giant Cells*/drug effects , Giant Cells*/metabolism , Giant Cells*/virology , Drug Evaluation, Preclinical*/methods, Animals ; Humans ; Genetic Vectors/genetics ; Antiviral Agents/pharmacology ; Suramin/pharmacology ; Ephrin-B2/metabolism ; Ephrin-B2/genetics ; Henipavirus Infections/virology ; Sf9 Cells ; Viral Fusion Proteins/genetics ; Viral Fusion Proteins/metabolism ; Virus Internalization/drug effects

المؤلفون: Kim S; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA., Ayan B; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA., Shayan M; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA., Rando TA; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA; Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto, Health Care System, Palo Alto, CA 94304, USA. Electronic address: trando@mednet.ucla.edu., Huang NF; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA; Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto, Health Care System, Palo Alto, CA 94304, USA; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA. Electronic address: ngantina@stanford.edu.

المصدر: Stem cell reports [Stem Cell Reports] 2024 Aug 13; Vol. 19 (8), pp. 1061-1073. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

مواضيع طبية MeSH: Weightlessness* , Regeneration*/drug effects , Drug Evaluation, Preclinical* , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/drug effects, Humans ; Insulin-Like Growth Factor I/metabolism ; Muscle Development/drug effects ; Lab-On-A-Chip Devices ; Tissue Engineering/methods ; Gene Expression Profiling

المؤلفون: Mathez G; Institute of Microbiology, University Hospital of Lausanne, University of Lausanne, 1011 Lausanne, Switzerland.; Department of Organic Chemistry, University of Chemistry and Technology Prague, 16628 Prague 6, Czech Republic., Brancale A; Department of Organic Chemistry, University of Chemistry and Technology Prague, 16628 Prague 6, Czech Republic., Cagno V; Institute of Microbiology, University Hospital of Lausanne, University of Lausanne, 1011 Lausanne, Switzerland.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2024 Aug 12; Vol. 64 (15), pp. 6190-6196. Date of Electronic Publication: 2024 Jul 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/drug effects , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , RNA, Viral*/metabolism , RNA, Viral*/antagonists & inhibitors , RNA, Viral*/genetics , Drug Evaluation, Preclinical*/methods, Humans ; Nucleic Acid Conformation ; Molecular Docking Simulation ; User-Computer Interface ; Models, Molecular

المؤلفون: Gao P; Therapeutics Development Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States., Tambe M; Therapeutics Development Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States., Chen CZ; Therapeutics Development Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States., Huang W; Therapeutics Development Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States., Tawa GJ; Therapeutics Development Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States., Hirschhorn T; Department of Biological Sciences, Department of Chemistry and Department of Pathology and Cell Biology, Columbia University, 550 West 120th Street MC 4846, 1208 Northwest Corner Building, New York, New York 10027, United States., Stockwell BR; Department of Biological Sciences, Department of Chemistry and Department of Pathology and Cell Biology, Columbia University, 550 West 120th Street MC 4846, 1208 Northwest Corner Building, New York, New York 10027, United States., Zheng W; Therapeutics Development Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States., Shen M; Early Translation Branch, Division of Preclinical Innovation, National Center for Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2024 Aug 12; Vol. 64 (15), pp. 6072-6080. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical* , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/metabolism, Humans ; Catalytic Domain ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors ; p38 Mitogen-Activated Protein Kinases/metabolism ; p38 Mitogen-Activated Protein Kinases/chemistry ; User-Computer Interface

المؤلفون: Teshima M; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan., Monobe K; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan., Okubo S; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan., Aoki S; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2024 Aug 10; Vol. 29 (16). Date of Electronic Publication: 2024 Aug 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Staphylococcus aureus*/drug effects , Staphylococcus aureus*/enzymology , Drug Evaluation, Preclinical*, Staphylococcus epidermidis/drug effects ; Staphylococcus epidermidis/enzymology ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Computer Simulation ; Drug Discovery ; Structure-Activity Relationship ; Peptide Synthases/antagonists & inhibitors ; Peptide Synthases/metabolism ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/chemistry ; Bacterial Proteins/antagonists & inhibitors ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Humans ; Molecular Dynamics Simulation

المؤلفون: Al Jaf AIA; Department of Biology, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy., Peria S; Department of Biology, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy., Fabiano T; Department of Biology, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy., Ragnini-Wilson A; Department of Biology, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.

المصدر: Cells [Cells] 2024 Aug 08; Vol. 13 (16). Date of Electronic Publication: 2024 Aug 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Remyelination*/drug effects , Drug Evaluation, Preclinical*, Humans ; Animals ; Demyelinating Diseases/drug therapy ; Demyelinating Diseases/pathology ; Myelin Sheath/metabolism ; Oligodendroglia/drug effects ; Oligodendroglia/metabolism ; Oligodendroglia/cytology ; Neural Stem Cells/drug effects ; Neural Stem Cells/metabolism ; Neural Stem Cells/cytology ; Cell Differentiation/drug effects

المؤلفون: Kiaris H; Department of Drug Discovery and Biomedical Sciences, College of Pharmacy and Peromyscus Genetic Stock Center, University of South Carolina, Columbia, SC, USA. hk@kiarislab.com.

المصدر: Lab animal [Lab Anim (NY)] 2024 Aug; Vol. 53 (8), pp. 187-188.

نوع المنشور: Journal Article; Letter

بيانات الدورية: Publisher: Nature America Country of Publication: United States NLM ID: 0417737 Publication Model: Print Cited Medium: Internet ISSN: 1548-4475 (Electronic) Linking ISSN: 00937355 NLM ISO Abbreviation: Lab Anim (NY) Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical*/methods, Animals ; Animal Experimentation/standards ; Animal Welfare

المؤلفون: Oh J; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea., Kwon OB; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea., Park SW; Department of Oral Biochemistry, School of Dentistry, Chonnam National University, Gwangju 61186, Republic of Korea., Kim JW; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea., Lee H; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea., Kim YK; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea., Choi EJ; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.; Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.; Department of Functional Genomics, Korea University of Science and Technology (UST), Daejeon 34113, Republic of Korea., Jung H; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.; Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.; Department of Functional Genomics, Korea University of Science and Technology (UST), Daejeon 34113, Republic of Korea., Choi DK; School of Life Science and Biotechnology, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea., Oh BJ; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu 41061, Republic of Korea., Min SH; Department of Innovative Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 21; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/cytology , Drug Evaluation, Preclinical*/methods , Cell Differentiation*/drug effects , Pluripotent Stem Cells*/drug effects , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/metabolism, Humans ; Cardiovascular Agents/pharmacology ; Calcium/metabolism ; Cardiotoxicity ; High-Throughput Screening Assays/methods ; HEK293 Cells ; Calcium Signaling/drug effects