المؤلفون: Cohen Shvefel S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Pai JA; Department of Pathology, Stanford University, Stanford, CA, USA., Cao Y; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Pal LR; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Levy R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Yao W; Department of Pathology, Stanford University, Stanford, CA, USA., Cheng K; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.; MSD R&D (China) Co., Ltd., Zemanek M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Bartok O; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Weller C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Yin Y; Department of Pathology, Stanford University, Stanford, CA, USA., Du PP; Department of Pathology, Stanford University, Stanford, CA, USA., Yakubovich E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Orr I; Bioinformatics Unit, Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Ben-Dor S; Bioinformatics Unit, Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Oren R; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Fellus-Alyagor L; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Golani O; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Goliand I; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Ranmar D; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Savchenko I; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Ketrarou N; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Schäffer AA; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Ruppin E; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Satpathy AT; Department of Pathology, Stanford University, Stanford, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Samuels Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 29. Date of Electronic Publication: 2023 Nov 29.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Taylor KR; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Barron T; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Hui A; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Spitzer A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Yalçin B; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Ivec AE; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Geraghty AC; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Hartmann GG; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Arzt M; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Gillespie SM; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Kim YS; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Maleki Jahan S; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Zhang H; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Shamardani K; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Su M; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Ni L; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Du PP; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Woo PJ; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Silva-Torres A; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Venkatesh HS; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Mancusi R; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Ponnuswami A; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Mulinyawe S; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Keough MB; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Chau I; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Aziz-Bose R; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Tirosh I; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Suvà ML; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., Monje M; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA. mmonje@stanford.edu.; Department of Pediatrics, Stanford University, Stanford, CA, USA. mmonje@stanford.edu.; Department of Pathology, Stanford University, Stanford, CA, USA. mmonje@stanford.edu.; Department of Neurosurgery, Stanford University, Stanford, CA, USA. mmonje@stanford.edu.; Howard Hughes Medical Institute, Stanford California, Stanford, CA, USA. mmonje@stanford.edu.

المصدر: Nature [Nature] 2023 Nov; Vol. 623 (7986), pp. 366-374. Date of Electronic Publication: 2023 Nov 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Adaptation, Physiological* , Glioma*/metabolism , Glioma*/pathology , Neuronal Plasticity* , Synapses*/metabolism, Animals ; Child ; Humans ; Brain-Derived Neurotrophic Factor/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cell Proliferation ; Disease Progression ; Glutamic Acid/metabolism ; Neurons/cytology ; Neurons/metabolism ; Receptor, trkB/genetics ; Receptor, trkB/metabolism ; Receptors, AMPA/metabolism ; Signal Transduction ; Tumor Microenvironment ; Optogenetics

المؤلفون: Durrant MG; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Fanton A; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Tycko J; Department of Genetics, Stanford University, Stanford, CA, USA., Hinks M; Department of Bioengineering, Stanford University, Stanford, CA, USA., Chandrasekaran SS; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Perry NT; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Schaepe J; Department of Bioengineering, Stanford University, Stanford, CA, USA., Du PP; Department of Genetics, Stanford University, Stanford, CA, USA.; Cancer Biology Program, Stanford University, Stanford, CA, USA., Lotfy P; Laboratory of Molecular and Cell Biology, Salk Institute for Biological Studies, La Jolla, CA, USA., Bassik MC; Department of Genetics, Stanford University, Stanford, CA, USA. bassik@stanford.edu., Bintu L; Department of Bioengineering, Stanford University, Stanford, CA, USA. lbintu@stanford.edu., Bhatt AS; Department of Genetics, Stanford University, Stanford, CA, USA. asbhatt@stanford.edu.; Department of Medicine (Hematology), Stanford University, Stanford, CA, USA. asbhatt@stanford.edu., Hsu PD; Arc Institute, Palo Alto, CA, USA. pdhsu@berkeley.edu.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Laboratory of Molecular and Cell Biology, Salk Institute for Biological Studies, La Jolla, CA, USA. pdhsu@berkeley.edu.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. pdhsu@berkeley.edu.

المصدر: Nature biotechnology [Nat Biotechnol] 2023 Apr; Vol. 41 (4), pp. 488-499. Date of Electronic Publication: 2022 Oct 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Integrases* , Genetic Engineering*, Humans ; Genome, Human ; Transfection ; Genomic Library

المؤلفون: Sun Y; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Revach OY; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Anderson S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kessler EA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wolfe CH; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jenney A; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA., Mills CE; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA., Robitschek EJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Davis TGR; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kim S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Fu A; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Ma X; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Gwee J; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Tiwari P; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Du PP; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sindurakar P; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Tian J; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Mehta A; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Schneider AM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Yizhak K; Department of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Institute of Technology, Technion, Haifa, Israel., Sade-Feldman M; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., LaSalle T; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Sharova T; Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Xie H; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Liu S; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA., Michaud WA; Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Saad-Beretta R; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Yates KB; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Iracheta-Vellve A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Spetz JKE; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA.; Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, MA, USA.; John B. Little Center for Radiation Sciences, Harvard School of Public Health, Boston, MA, USA., Qin X; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA.; Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, MA, USA.; John B. Little Center for Radiation Sciences, Harvard School of Public Health, Boston, MA, USA., Sarosiek KA; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA.; Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, MA, USA.; John B. Little Center for Radiation Sciences, Harvard School of Public Health, Boston, MA, USA., Zhang G; Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA, USA.; Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University School of Medicine, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Department of Pathology, Duke University School of Medicine, Durham, NC, USA., Kim JW; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Center for Novel Therapeutics, UC San Diego, La Jolla, CA, USA.; Department of Medicine, UC San Diego, La Jolla, CA, USA., Su MY; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Cicerchia AM; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Rasmussen MQ; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Klempner SJ; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Juric D; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Pai SI; Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital, Boston, MA, USA., Miller DM; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Giobbie-Hurder A; Division of Biostatistics, Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA., Chen JH; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Pelka K; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Frederick DT; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Stinson S; Gilead Sciences, Foster City, CA, USA., Ivanova E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA., Aref AR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA.; Xsphera Biosciences, Boston, MA, USA., Paweletz CP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA., Barbie DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA., Sen DR; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Fisher DE; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Corcoran RB; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Hacohen N; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sorger PK; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA., Flaherty KT; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Boland GM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Manguso RT; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jenkins RW; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. rjenkins@mgh.harvard.edu.; Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Sciences, Harvard Medical School, Boston, MA, USA. rjenkins@mgh.harvard.edu.

المصدر: Nature [Nature] 2023 Mar; Vol. 615 (7950), pp. 158-167. Date of Electronic Publication: 2023 Jan 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Immune Evasion*/genetics , Immune Evasion*/immunology , Immunotherapy*/methods , Protein Serine-Threonine Kinases*/antagonists & inhibitors , Protein Serine-Threonine Kinases*/genetics , Drug Resistance, Neoplasm*, Humans ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Organoids ; Tumor Necrosis Factors/immunology ; Interferon-gamma/immunology ; Spheroids, Cellular ; Caspases ; Janus Kinases ; STAT Transcription Factors

المؤلفون: Dubrot J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain., Du PP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanford University School of Medicine, Stanford, CA, USA., Lane-Reticker SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kessler EA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Muscato AJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mehta A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Freeman SS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Allen PM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Olander KE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ockerman KM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wolfe CH; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wiesmann F; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Knudsen NH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Tsao HW; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Iracheta-Vellve A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schneider EM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rivera-Rosario AN; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kohnle IC; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pope HW; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ayer A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mishra G; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zimmer MD; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kim SY; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mahapatra A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ebrahimi-Nik H; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Frederick DT; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Boland GM; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Haining WN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; ArsenalBio, South San Francisco, CA, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Doench JG; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hacohen N; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Yates KB; Broad Institute of MIT and Harvard, Cambridge, MA, USA. yates@broadinstitute.org.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA. yates@broadinstitute.org.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. yates@broadinstitute.org., Manguso RT; Broad Institute of MIT and Harvard, Cambridge, MA, USA. rmanguso@mgh.harvard.edu.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA. rmanguso@mgh.harvard.edu.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. rmanguso@mgh.harvard.edu.

المصدر: Nature immunology [Nat Immunol] 2022 Oct; Vol. 23 (10), pp. 1495-1506. Date of Electronic Publication: 2022 Sep 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes* , Neoplasms*, Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Histocompatibility Antigens Class I/metabolism ; Humans ; Immune Checkpoint Inhibitors ; Immune Evasion ; Interferon-gamma/genetics ; Interferon-gamma/metabolism ; NK Cell Lectin-Like Receptor Subfamily C

المؤلفون: Zhang SQY; School of Public Health, Kunming Medical University, Kunming 650500, China Kunming Panlong District People's Hospital (Medical Department) , Kunming 650500, China., Du PP; Community Health Service Center of Changle Square, Beilin District, Xi'an 710000., Shu X; School of Public Health, Kunming Medical University, Kunming 650500, China., Wu HX; School of Public Health, Kunming Medical University, Kunming 650500, China., Mu YZ; School of Public Health, Kunming Medical University, Kunming 650500, China., Wu XN; Graduate School, Kunming Medical University, Kunming 650500, China., Zhang Y; Biomedical Engineering Institute, Kunming Medical University, Kunming 650500, China.

المصدر: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases [Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi] 2022 Sep 20; Vol. 40 (9), pp. 656-660.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Tianjin shi lao dong wei sheng yan jiu suo ; Tianjin shi lao dong wei sheng huan jing yi xue hui Country of Publication: China NLM ID: 8410840 Publication Model: Print Cited Medium: Print ISSN: 1001-9391 (Print) Linking ISSN: 10019391 NLM ISO Abbreviation: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Electromagnetic Fields* , Nerve Growth Factor*, Animals ; Female ; Hippocampus ; Male ; Mice ; Pregnancy ; Rats ; Rats, Wistar ; Semen

المؤلفون: Du PP; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Liu K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.; Program in Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA, USA., Hess GT; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA. ghess3@wisc.edu.; Center for Human Genomics and Precision Medicine, University of Wisconsin-Madison, Madison, WI, USA. ghess3@wisc.edu.

المصدر: Nature biotechnology [Nat Biotechnol] 2022 Jun; Vol. 40 (6), pp. 834-836.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease*, Humans ; Mutation

المؤلفون: Griffin GK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Wu J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Iracheta-Vellve A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Patti JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hsu J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Davis T; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dele-Oni D; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Du PP; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Halawi AG; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ishizuka JJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; Department of Internal Medicine (Oncology), Yale Cancer Center and Yale School of Medicine, New Haven, CT, USA., Kim SY; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Klaeger S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Knudsen NH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Miller BC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; Department of Immunology and Evergrande Center for Immunological Diseases, Harvard Medical School, Boston, MA, USA., Nguyen TH; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Olander KE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Papanastasiou M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rachimi S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Robitschek EJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Schneider EM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Yeary MD; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zimmer MD; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jaffe JD; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Inzen Therapeutics, Cambridge, MA, USA., Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Doench JG; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Haining WN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.; Merck, Boston, MA, USA., Yates KB; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Manguso RT; Broad Institute of MIT and Harvard, Cambridge, MA, USA. rmanguso@mgh.harvard.edu.; Department of Medicine and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. rmanguso@mgh.harvard.edu., Bernstein BE; Broad Institute of MIT and Harvard, Cambridge, MA, USA. bernstein.bradley@mgh.harvard.edu.; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. bernstein.bradley@mgh.harvard.edu.

المصدر: Nature [Nature] 2021 Jul; Vol. 595 (7866), pp. 309-314. Date of Electronic Publication: 2021 May 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Gene Silencing*, Histone-Lysine N-Methyltransferase/*metabolism , Neoplasms/*genetics , Neoplasms/*immunology, Animals ; Antigens, Viral/immunology ; CRISPR-Cas Systems/genetics ; Chromatin/genetics ; Chromatin/metabolism ; DNA Transposable Elements/genetics ; Disease Models, Animal ; Female ; Histocompatibility Antigens Class I/genetics ; Histocompatibility Antigens Class I/immunology ; Humans ; Mice ; Neoplasms/drug therapy ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; T-Lymphocytes, Cytotoxic/cytology ; T-Lymphocytes, Cytotoxic/immunology

المؤلفون: Dubrot J; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Lane-Reticker SK; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Kessler EA; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Ayer A; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Mishra G; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Wolfe CH; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Zimmer MD; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Du PP; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Mahapatra A; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Ockerman KM; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Davis TGR; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Kohnle IC; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Pope HW; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Allen PM; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Olander KE; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Iracheta-Vellve A; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Doench JG; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Haining WN; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA; Division of Pediatric Hematology and Oncology, Children's Hospital, Boston, MA, USA; Merck Research Laboratories, Boston, MA, USA., Yates KB; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. Electronic address: yates@broadinstitute.org., Manguso RT; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. Electronic address: rmanguso@broadinstitute.org.

المصدر: Immunity [Immunity] 2021 Mar 09; Vol. 54 (3), pp. 571-585.e6. Date of Electronic Publication: 2021 Jan 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Renal Cell/*immunology , Genetic Testing/*methods , Genetic Vectors/*genetics , Immunotherapy/*methods , Kidney Neoplasms/*immunology , Killer Cells, Natural/*immunology , Lentivirus/*genetics, Animals ; Antigen Presentation ; Autophagy ; Carcinoma, Renal Cell/therapy ; Cells, Cultured ; Clustered Regularly Interspaced Short Palindromic Repeats ; Genetic Engineering ; Histocompatibility Antigens Class I/metabolism ; Kidney Neoplasms/therapy ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Molecular Targeted Therapy

المؤلفون: Du PP; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China., Huang YH; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China., Lü H; College of Natural Resources and Environment, South China Agricultural University, Guangzhou, 510642, China., Xiang L; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China., Li YW; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China., Li H; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China., Mo CH; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China., Cai QY; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. Electronic address: caiqy@jnu.edu.cn., Li QX; Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, HI, 96822, USA.

المصدر: Environmental research [Environ Res] 2020 Jul; Vol. 186, pp. 109611. Date of Electronic Publication: 2020 Apr 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE

مواضيع طبية MeSH: Oryza* , Phthalic Acids* , Soil Pollutants*/analysis, Biological Availability ; Esters ; Soil