المؤلفون: Barth A; Global Blood Therapeutics, South San Francisco, California, USA., Perry CR; GSK, Collegeville, Pennsylvania, USA., Shabbir S; GSK, Stevenage, UK., Zamek-Gliszczynski MJ; GSK, Collegeville, Pennsylvania, USA., Thomas S; GSK, Collegeville, Pennsylvania, USA., Dumont EF; Boston Pharmaceuticals, Cambridge, Massachusetts, USA., Brimhall DB; PPD, Las Vegas, Nevada, USA., Nguyen D; GSK, Collegeville, Pennsylvania, USA., Srinivasan M; GSK, Collegeville, Pennsylvania, USA., Swift B; GSK, Durham, North Carolina, USA.

المصدر: Clinical and translational science [Clin Transl Sci] 2023 Apr; Vol. 16 (4), pp. 647-661. Date of Electronic Publication: 2023 Jan 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP3A*/metabolism , Itraconazole*/pharmacology, Humans ; Rifampin/pharmacology ; Midazolam ; Cimetidine ; Drug Interactions ; Pharmaceutical Preparations ; Membrane Transport Proteins ; Digoxin ; Models, Biological

المؤلفون: Scangarella-Oman NE; GSK Collegeville, Collegeville, Pennsylvania, USA nicole.e.scangarella-oman@gsk.com., Hossain M; GSK Collegeville, Collegeville, Pennsylvania, USA., Perry CR; GSK Collegeville, Collegeville, Pennsylvania, USA., Tiffany C; GSK Collegeville, Collegeville, Pennsylvania, USA., Powell M; GSK, Research Triangle Park, North Carolina, USA., Swift B; GSK, Research Triangle Park, North Carolina, USA., Dumont EF; GSK Collegeville, Collegeville, Pennsylvania, USA.

المصدر: Sexually transmitted infections [Sex Transm Infect] 2023 Feb; Vol. 99 (1), pp. 64-69. Date of Electronic Publication: 2022 Nov 21.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9805554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-3263 (Electronic) Linking ISSN: 13684973 NLM ISO Abbreviation: Sex Transm Infect Subsets: MEDLINE

مواضيع طبية MeSH: Gonorrhea*/drug therapy , Gonorrhea*/microbiology, Humans ; Acetylcholinesterase/pharmacology ; Acetylcholinesterase/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Acenaphthenes/pharmacology ; Acenaphthenes/therapeutic use ; Neisseria gonorrhoeae ; Microbial Sensitivity Tests ; Clinical Trials, Phase III as Topic

المؤلفون: Barth A; GSK, Collegeville, Pennsylvania, USA.; Present affiliation: Global Blood Therapeutics, San Francisco, California, USA., Hossain M; GSK, Collegeville, Pennsylvania, USA.; Present affiliation: Servier Pharmaceuticals, Boston, Massachusetts, USA., Perry CR; GSK, Collegeville, Pennsylvania, USA., Gross AS; GSK R&D, Sydney, AU., Ogura H; GSK, Tokyo, Japan., Shabbir S; GSK, Stevenage, UK., Thomas S; GSK, Collegeville, Pennsylvania, USA., Dumont EF; GSK, Collegeville, Pennsylvania, USA.; Present affiliation: Boston Pharmaceuticals, Cambridge, Massachusetts, USA., Brimhall DB; PPD, Las Vegas, Nevada, USA., Srinivasan M; GSK, Collegeville, Pennsylvania, USA., Swift B; GSK, Durham, North Carolina, USA.

المصدر: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Jan; Vol. 12 (1), pp. 38-56. Date of Electronic Publication: 2022 Dec 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

مواضيع طبية MeSH: Acenaphthenes*/pharmacokinetics , Heterocyclic Compounds, 3-Ring*/pharmacokinetics, Humans ; Healthy Volunteers ; Anti-Bacterial Agents/pharmacokinetics

المؤلفون: Tiffany C; GSK, Collegeville, Pennsylvania, USA., Dumont EF; GSK, Collegeville, Pennsylvania, USA., Hossain M; GSK, Collegeville, Pennsylvania, USA., Srinivasan M; GSK, Collegeville, Pennsylvania, USA., Swift B; GSK, Research Triangle Park, North Carolina, USA.

المصدر: Clinical and translational science [Clin Transl Sci] 2022 Sep; Vol. 15 (9), pp. 2251-2264. Date of Electronic Publication: 2022 Jul 13.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Single-Blind Method*, Acenaphthenes ; Administration, Oral ; Adult ; Aged ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Healthy Volunteers ; Heterocyclic Compounds, 3-Ring ; Humans

المؤلفون: Scangarella-Oman NE; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA., Hossain M; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA., Hoover JL; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA., Perry CR; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA., Tiffany C; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA., Barth A; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA., Dumont EF; Research and Development, GlaxoSmithKline plc, Upper Providence, Pennsylvania, USA.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Mar 15; Vol. 66 (3), pp. e0149221. Date of Electronic Publication: 2022 Jan 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Acenaphthenes*/pharmacology , Urinary Tract Infections*/drug therapy, Adolescent ; Animals ; Anti-Bacterial Agents/pharmacology ; Clinical Trials, Phase III as Topic ; Female ; Heterocyclic Compounds, 3-Ring/pharmacology ; Humans ; Microbial Sensitivity Tests ; Multicenter Studies as Topic ; Randomized Controlled Trials as Topic

المؤلفون: Barth A; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Hossain M; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Brimhall DB; PPD, Las Vegas, Nevada, USA., Perry CR; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Tiffany CA; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Xu S; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Dumont EF; GlaxoSmithKline, Collegeville, Pennsylvania, USA.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Jan 18; Vol. 66 (1), pp. e0126321. Date of Electronic Publication: 2021 Oct 11.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Acenaphthenes*/pharmacokinetics , Topoisomerase Inhibitors*, Administration, Oral ; Adolescent ; Adult ; Area Under Curve ; Biological Availability ; Cross-Over Studies ; Heterocyclic Compounds, 3-Ring/pharmacokinetics ; Humans ; Tablets

المؤلفون: Nuzzo A; Human Genetics, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK. andrea.8.nuzzo@gsk.com., Van Horn S; Functional Genomics, GlaxoSmithKline R&D, Collegeville, PA, USA., Traini C; Functional Genomics, GlaxoSmithKline R&D, Collegeville, PA, USA., Perry CR; Development, GlaxoSmithKline R&D, Collegeville, PA, USA., Dumont EF; Development, GlaxoSmithKline R&D, Collegeville, PA, USA., Scangarella-Oman NE; Medicines Opportunities Research Unit, GlaxoSmithKline R&D, Collegeville, PA, USA., Gardiner DF; Development, GlaxoSmithKline R&D, Collegeville, PA, USA., Brown JR; Human Genetics, GlaxoSmithKline R&D, Collegeville, PA, USA.; Kaleido Biosciences, 65 Hayden Avenue, Lexington, MA, 02421, USA.

المصدر: BMC microbiology [BMC Microbiol] 2021 Oct 26; Vol. 21 (1), pp. 293. Date of Electronic Publication: 2021 Oct 26.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2180 (Electronic) Linking ISSN: 14712180 NLM ISO Abbreviation: BMC Microbiol Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Nuzzo A; Human Genetics, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK. andrea.8.nuzzo@gsk.com., Van Horn S; Functional Genomics, GlaxoSmithKline R&D, Collegeville, PA, USA., Traini C; Functional Genomics, GlaxoSmithKline R&D, Collegeville, PA, USA., Perry CR; Development, GlaxoSmithKline R&D, Collegeville, PA, USA., Dumont EF; Development, GlaxoSmithKline R&D, Collegeville, PA, USA., Scangarella-Oman NE; Medicines Opportunities Research Unit, GlaxoSmithKline R&D, Collegeville, PA, USA., Gardiner DF; Development, GlaxoSmithKline R&D, Collegeville, PA, USA., Brown JR; Human Genetics, GlaxoSmithKline R&D, Collegeville, PA, USA.; Present Address: Kaleido Biosciences, 65 Hayden Avenue, Lexington, MA, 02421, USA.

المصدر: BMC microbiology [BMC Microbiol] 2021 Jun 15; Vol. 21 (1), pp. 181. Date of Electronic Publication: 2021 Jun 15.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2180 (Electronic) Linking ISSN: 14712180 NLM ISO Abbreviation: BMC Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Acenaphthenes/*administration & dosage , Anti-Bacterial Agents/*administration & dosage , Heterocyclic Compounds, 3-Ring/*administration & dosage , Microbiota/*drug effects , Urinary Tract Infections/*drug therapy, Acenaphthenes/pharmacokinetics ; Adult ; Anti-Bacterial Agents/pharmacokinetics ; Bacteria/classification ; Bacteria/drug effects ; Bacteria/genetics ; Bacteria/isolation & purification ; Biodiversity ; Female ; Gastrointestinal Tract/microbiology ; Heterocyclic Compounds, 3-Ring/pharmacokinetics ; Humans ; Middle Aged ; Pharynx/microbiology ; Urinary Tract Infections/microbiology ; Vagina/microbiology

المؤلفون: Overcash JS; eStudySite, La Mesa, California, USA., Tiffany CA; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Scangarella-Oman NE; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Perry CR; GlaxoSmithKline, Collegeville, Pennsylvania, USA Caroline.R.Perry@gsk.com Etienne.F.Dumont@gsk.com., Tao Y; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Hossain M; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Barth A; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Dumont EF; GlaxoSmithKline, Collegeville, Pennsylvania, USA Caroline.R.Perry@gsk.com Etienne.F.Dumont@gsk.com.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Jun 23; Vol. 64 (7). Date of Electronic Publication: 2020 Jun 23 (Print Publication: 2020).

نوع المنشور: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Cystitis*/drug therapy , Urinary Tract Infections*/drug therapy, Acenaphthenes ; Anti-Bacterial Agents/therapeutic use ; Female ; Heterocyclic Compounds, 3-Ring ; Humans ; Microbial Sensitivity Tests

المؤلفون: Dumont EF; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Oliver AJ; GlaxoSmithKline, Middlesex, United Kingdom., Ioannou C; GlaxoSmithKline, Middlesex, United Kingdom., Billiard J; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Dennison J; Hammersmith Medicines Research Ltd., London, United Kingdom., van den Berg F; Hammersmith Medicines Research Ltd., London, United Kingdom., Yang S; GlaxoSmithKline, Middlesex, United Kingdom., Chandrasekaran V; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Young GC; GlaxoSmithKline, Ware, United Kingdom., Lahiry A; GlaxoSmithKline, Bangalore, India., Starbuck DC; GlaxoSmithKline, Ware, United Kingdom., Harrell AW; GlaxoSmithKline, Ware, United Kingdom., Georgiou A; GlaxoSmithKline, Ware, United Kingdom., Hopchet N; Hammersmith Medicines Research Ltd., London, United Kingdom., Gillies A; Gillies Associates Limited, Harrogate, United Kingdom., Baker SJ; GlaxoSmithKline, Collegeville, Pennsylvania, USA stephen.8.baker@gsk.com.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Apr 21; Vol. 64 (5). Date of Electronic Publication: 2020 Apr 21 (Print Publication: 2020).

نوع المنشور: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Dry Powder Inhalers*/adverse effects, Antiviral Agents/*administration & dosage , Lung/*metabolism , Pulmonary Disease, Chronic Obstructive/*metabolism , Ribavirin/*administration & dosage, Administration, Inhalation ; Adult ; Aged ; Antiviral Agents/pharmacokinetics ; Antiviral Agents/therapeutic use ; Double-Blind Method ; Drug Delivery Systems ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/virology ; Respiratory Mucosa/metabolism ; Ribavirin/pharmacokinetics ; Ribavirin/therapeutic use ; Young Adult