المؤلفون: Erin E. Gaughan, Tom M. Quinn, Andrew Mills, Annya M. Bruce, Jean Antonelli, Alison C. MacKinnon, Vassilios Aslanis, Feng Li, Richard O’Connor, Cecilia Boz, Ross Mills, Philip Emanuel, Matthew Burgess, Giulia Rinaldi, Asta Valanciute, Bethany Mills, Emma Scholefield, Gareth Hardisty, Emily Gwyer Findlay, Richard A. Parker, John Norrie, James W. Dear, Ahsan R. Akram, Oliver Koch, Kate Templeton, David H. Dockrell, Timothy S. Walsh, Stephen Partridge, Duncan Humphries, Jie Wang-Jairaj, Robert J. Slack, Hans Schambye, De Phung, Lise Gravelle, Bertil Lindmark, Manu Shankar-Hari, Nikhil Hirani, Tariq Sethi, Kevin Dhaliwal

المصدر: American Journal of Respiratory and Critical Care Medicine. 207:138-149

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Critical Care and Intensive Care Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43fb8472c9f7aba3f7abdc6b479f8ec2
https://doi.org/10.1164/rccm.202203-0477oc

المؤلفون: Antonio Fernandez, Matthieu Vermeren, Duncan Humphries, Ramon Subiros-Funosas, Nicole Barth, Lara Campana, Alison MacKinnon, Yi Feng, Marc Vendrell

المصدر: ACS Central Science, Vol 3, Iss 9, Pp 995-1005 (2017)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7943; https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/f506f907e6ad4acea2ef4f4aa57ec23b

المؤلفون: Erin E, Gaughan, Tom M, Quinn, Andrew, Mills, Annya M, Bruce, Jean, Antonelli, Alison, MacKinnon, Vassilios, Aslanis, Feng, Li, Richard, O'Connor, Cecilia, Boz, Ross, Mills, Philip, Emanuel, Matthew, Burgess, Giulia, Rinaldi, Asta, Valanciute, Bethany, Mills, Emma, Scholefield, Gareth, Hardisty, Emily, Gwyer Findlay, Richard A, Parker, John, Norrie, James W, Dear, Ahsan R, Akram, Oliver, Koch, Kate, Templeton, David H, Dockrell, Timothy S, Walsh, Stephen, Partridge, Duncan, Humphries, Jie, Wang-Jairaj, Robert J, Slack, Hans, Schambye, De, Phung, Lise, Gravelle, Bertil, Lindmark, Manu, Shankar-Hari, Nikhil, Hirani, Tariq, Sethi, Kevin, Dhaliwal

المصدر: Gaughan, E E, Quinn, T M, Mills, A, Bruce, A M, Antonelli, J, Mackinnon, A, Aslanis, V, Li, F, O'connor, R, Boz, C, Mills, R, Emanuel, P, Burgess, M, Rinaldi, G, Valanciute, A, Mills, B, Scholefield, E, Hardisty, G, Gwyer Findlay, E, Parker, R A, Norrie, J, Dear, J W, Akram, A R, Koch, O, Templeton, K, Dockrell, D H, Walsh, T S, Partridge, S, Humphries, D, Wang-jairaj, J, Slack, R J, Schambye, H, Phung, D, Gravelle, L, Lindmark, B, Shankar-Hari, M, Hirani, N, Sethi, T & Dhaliwal, K 2022, ' An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE) : A Phase Ib/IIa Randomised Controlled Trial ', American Journal of Respiratory and Critical Care Medicine . https://doi.org/10.1164/rccm.202203-0477OC

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4cbdceb9f003b857818278fa3a4d79ec
https://www.pure.ed.ac.uk/ws/files/298426001/rccm.202203_0477oc_1_.pdf

المؤلفون: Ali Taimori, Duncan Humphries, Gareth Williams, Kevin Dhaliwal, Neil Finlayson, James Hopgood

المصدر: Taimori, A, Humphries, D, Williams, G, Dhaliwal, K, Finlayson, N & Hopgood, J R 2022, ' Fast and robust single-exponential decay recovery from noisy fluorescence lifetime imaging ', IEEE Transactions on Biomedical Engineering, vol. 69, no. 12, pp. 3703-3716 . https://doi.org/10.1109/TBME.2022.3176224

مصطلحات موضوعية: game theory, Fluorescence Lifetime Imaging Microscopy, multi-resolution representation, Signal recovery, single-exponential decay, rapid lifetime determination, Optical Imaging, Biomedical Engineering, Adaptive filtering, binning, Microscopy, Fluorescence, multiresolution representation, Least-Squares Analysis, lifetime estimation, Fluorescent Dyes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a547f840bf9f58b37f4e30bdef2a6b2b
https://pubmed.ncbi.nlm.nih.gov/35609109

المؤلفون: Vincent Pavot, Kevin Dhaliwal, Duncan Humphries, Richard A. O’Connor, Daniel Larocque, Martine Chabaud-Riou

المصدر: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Humphries, D C, O’connor, R A, Larocque, D, Chabaud-riou, M, Dhaliwal, K & Pavot, V 2021, ' Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections ', Frontiers in Immunology, vol. 12 . https://doi.org/10.3389/fimmu.2021.738955

مصطلحات موضوعية: Immunology, Context (language use), Review, Biology, EVLP, lung, resident memory T cells, Memory T Cells, Memory B Cells, Antigen, Immunity, resident memory B cells, medicine, Animals, Humans, Immunology and Allergy, Respiratory Tract Infections, in situ optical imaging, Lung, Effector, Respiratory infection, Viral Vaccines, Bacterial Infections, RC581-607, vaccination, infection, Vaccination, Phenotype, medicine.anatomical_structure, Immunization, Virus Diseases, Bacterial Vaccines, Host-Pathogen Interactions, Immunologic diseases. Allergy, Immunologic Memory

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905ccca739e486f62c3094aa3fc0e358
https://doi.org/10.3389/fimmu.2021.738955

المؤلفون: Anette Melk, David P. Baird, Sarah A. Neely, Paul Krimpenfort, Sofia Ferreira-Gonzalez, Jeremy Hughes, Marie-Helena Docherty, Duncan Humphries, Roland Schmitt, Katie J. Mylonas, David A. Ferenbach, Eoin O'Sullivan, Stuart J. Forbes

المصدر: Mylonas, K J, O'Sullivan, E, Humphries, D, Baird, D, Docherty, M-H, Neely, S, Krimpenfort, P, Melk, A, Schmitt, R, Ferreira-Gonzalez, S, Forbes, S J, Hughes, J & Ferenbach, D A 2021, ' Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair ', Science Translational Medicine . https://doi.org/10.1126/scitranslmed.abb0203

مصطلحات موضوعية: 0301 basic medicine, Radiation Nephropathy, Senescence, Kidney, Mice, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, medicine, Animals, Regeneration, Senolytic, Cellular Senescence, business.industry, Regeneration (biology), General Medicine, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Reperfusion Injury, 030220 oncology & carcinogenesis, Cancer research, business, Kidney disease, Transforming growth factor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6807ac36b7eef2036175beb443aad0
https://www.pure.ed.ac.uk/ws/files/211798980/Full_manuscript_as_pdf.pdf

المؤلفون: Andrew J. M. Howden, Sarah R. Walmsley, Alex von Kriegsheim, Jens L. Hukelmann, Eilise M. Ryan, Rebecca S. Dickinson, Fiona Murphy, Gio Rodriguez Blanco, Bart Ghesquière, Patrícia Coelho, Doreen A. Cantrell, Emily R. Watts, Pranvera Sadiku, Robert Grecian, Ananda S. Mirchandani, Wesley Vermaelen, Tyler Morrison, Duncan Humphries, Tracie Plant, Moira K. B. Whyte, Andrew J. Finch

المصدر: Watts, E R, Howden, A J M, Morrison, T, Sadiku, P, Hukelmann, J L, Von Kriegsheim, A, Ghesquière, B, Murphy, F, Mirchandani, A S, Humphries, D C, Grecian, R, Ryan, E M, Coelho, P, Rodriguez-blanco, G, Plant, T M, Dickinson, R S, Finch, A J, Vermaelen, W, Cantrell, D A, Whyte, M K B & Walmsley, S R 2021, ' Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism ', Journal of Clinical Investigation . https://doi.org/10.1172/JCI134073

مصطلحات موضوعية: Inflammation, Proteomics, 0301 basic medicine, Neutrophils, Chemistry, Catabolism, General Medicine, Metabolism, Lung injury, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cell surface receptor, 030220 oncology & carcinogenesis, Proteome, medicine, medicine.symptom, Signal transduction, Hypoxia

وصف الملف: application/pdf; Print

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a5393e0379a24b90ce692f5f16f351
https://hdl.handle.net/20.500.11820/6ee67df8-79e3-477f-a412-02d6f22765b7

المؤلفون: Thane A. Campbell, James W. Dear, Annya Bruce, Bethany Mills, Tashfeen Walton, Emma Scholefield, Adam Marshall, Neil Q. McDonald, Thomas H. Craven, Timothy S. Walsh, Duncan Humphries, Ahsan R. Akram, Kevin Dhaliwal, David E. Newby, Christopher Haslett, Joanne Mair, Adam T. Hill

المصدر: Craven, T H, Walton, T, Akram, A R, Scholefield, E, Mcdonald, N, Marshall, A D L, Humphries, D C, Mills, B, Campbell, T A, Bruce, A, Mair, J, Dear, J W, Newby, D E, Hill, A T, Walsh, T S, Haslett, C & Dhaliwal, K 2021, ' Activated neutrophil fluorescent imaging technique for human lungs ', Scientific Reports, vol. 11, no. 1 . https://doi.org/10.1038/s41598-020-80083-w
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, medicine.medical_specialty, Neutrophils, Science, Inflammation, Cellular imaging, Article, Neutrophil Activation, 03 medical and health sciences, 0302 clinical medicine, In vivo, Endomicroscopy, medicine, Animals, Humans, Lung, Respiratory tract diseases, Multidisciplinary, Pancreatic Elastase, business.industry, Pinocytosis, Elastase, In vitro, Bronchiectasis, 030104 developmental biology, Spectrometry, Fluorescence, 030228 respiratory system, Medicine, Molecular imaging, medicine.symptom, business, Ex vivo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856a21122b702775030cfd15054a6b98
https://www.pure.ed.ac.uk/ws/files/191779842/s41598_020_80083_w_1_.pdf

المؤلفون: Nikhil Hirani, Robert J. Slack, Hans Thalsgaard Schambye, Duncan Humphries, A. John Simpson, Ian Forrest, Fredrik Zetterberg, Lucy Keeling, Michael A Gibbons, Wendy Funston, Paul Ford, Toby M. Maher, Ulf J. Nilsson, Tariq Sethi, Anders Pedersen, Lyn Paul, Philip L. Molyneaux, Ross Mills, Alison C. MacKinnon, Hakon Leffler, Lise Gravelle, Lisa Nicol, Feng Li, Susan Tantawi, Utsa Karmakar

المساهمون: National Institute for Health Research, British Lung Foundation

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Galectin 3, Respiratory System, Cmax, Gastroenterology, 03 medical and health sciences, Idiopathic pulmonary fibrosis, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Internal medicine, medicine, Humans, Lung, 11 Medical and Health Sciences, medicine.diagnostic_test, business.industry, CCL18, respiratory system, medicine.disease, Idiopathic Pulmonary Fibrosis, 030104 developmental biology, medicine.anatomical_structure, Bronchoalveolar lavage, 030228 respiratory system, Tolerability, Galectin-3, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4821d3d0249b9f434433b15c5cc88fd
http://hdl.handle.net/10044/1/85036

المؤلفون: Cécile Bénézech, Carolynn Cairns, Oliver Teenan, Katie Connor, James O’sullivan, Angela Salzano, David A. Ferenbach, Kevin Stewart, Eoin O'Sullivan, Neil C. Henderson, Peng Ding, Riinu Pius, Jeremy Hughes, Tamir Chandra, Laura Denby, Duncan Humphries, Prakash Ramachandran, Bryan R. Conway, Daniel J. Simpson

المساهمون: Conway, B. R., O'Sullivan, E. D., Cairns, C., O'Sullivan, J., Simpson, D. J., Salzano, A., Connor, K., Ding, P., Humphries, D., Stewart, K., Teenan, O., Pius, R., Henderson, N. C., Benezech, C., Ramachandran, P., Ferenbach, D., Hughes, J., Chandra, T., Denby, L.

المصدر: J Am Soc Nephrol
Conway, B R, O Sullivan, E, Cairns, C, O'Sullivan, J, Simpson, D, Salzano, A, Connor, K, Ding, P, Humphries, D, Stewart, K, Teenan, O, Pius, R, Henderson, N C, Benezech, C, Ramachandran, P, Ferenbach, D A, Hughes, J, Chandra, T & Denby, L 2020, ' Kidney single-cell atlas reveals myeloid heterogeneity in progression and regression of kidney disease ', Journal of the American Society of Nephrology, vol. 31, no. 12, pp. 2833–2854 . https://doi.org/10.1681/ASN.2020060806

مصطلحات موضوعية: 0301 basic medicine, Male, Cell type, Myeloid, scRNA sequencing, kidney disease, Cell, 030232 urology & nephrology, Biology, Proinflammatory cytokine, Flow cytometry, Transcriptome, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Myeloid Cells, Kidney, medicine.diagnostic_test, Sequence Analysis, RNA, Macrophages, fibrosis, General Medicine, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Basic Research, Nephrology, myeloid cells, Cancer research, Disease Progression, Kidney Diseases, Single-Cell Analysis, Kidney disease, Ureteral Obstruction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c985622a807b7b39dbcfe20eb66ca7
https://pubmed.ncbi.nlm.nih.gov/32978267