نتائج البحث - "EBRU DESTAN"

المساهمون: Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Dağ, Çağdaş, Shafiei, Alaleh, Güven, Ömür, Besler, Sabri Özkan, Ertem, Fatma Betül, Çiftçi, Halilibrahim, Tateishi, Hiroshi, Koiwai, Kotaro, Koga, Ryoko, Anraku, Kensaku, Monde, Kazuaki, Destan, Ebru, Yüksel, Büşra, Ayan, Esra, Yıldırım, Günseli, Yığın, Merve, Sierra, Raymond G., Yoon, Chun Hong, Su, Zhen, Liang, Mengling, Acar, Burçin, Haliloğlu, Türkan, Otsuka, Masami, Yumoto, Fumiaki, Fujita, Mikako, Senda, Toshiya, Koç Üniversitesi İş Bankası Enfeksiyon Hastalıkları Uygulama ve Araştırma Merkezi (EHAM) / Koç University İşbank Center for Infectious Diseases (KU-IS CID), College of Sciences, Graduate School of Sciences and Engineering, Department of Molecular Biology and Genetics

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports

مصطلحات موضوعية: Models, Molecular, Cyclitol, Protein Conformation, Science, Association (object-oriented programming), Human immunodeficiency virus (HIV), HIV Infections, Crystal structure, Crystallography, X-Ray, medicine.disease_cause, Article, World health, chemistry.chemical_compound, Protein Domains, medicine, Molecule, Humans, Protein Precursors, Binding site, X-ray crystallography, Budding, Multidisciplinary, Binding Sites, Viral matrix protein, Chemistry, Virus Assembly, Cell Membrane, Binding sites, Cell membrane, HIV infections, HIV-1, Models molecular, Phosphoric monoester hydrolases, Protein conformation, Protein domains, Protein precursors, Virus assembly, Phosphoric Monoester Hydrolases, Multidisciplinary sciences, Science and technology, Membrane, Virion assembly, Biophysics, Medicine, Structural biology

وصف الملف: pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ba8bb3719fb61500020f51b8babec4
https://doi.org/10.1101/2021.02.21.432153

9

Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing

المؤلفون: Gunseli Yildirim, Alaleh Shafiei, Oleksandr Yefanov, Hasan DeMirci, Frédéric Poitevin, Timucin Avsar, Chun Hong Yoon, Muge Didem Orhan, Merve Yigin, Lalehan Oktay, Fulya Aksit, Çağdaş Dağ, Serdar Durdagi, Christopher Kupitz, Omur Guven, Valerio Mariani, Ece Erdemoglu, Ebru Destan, Edward H. Snell, Ismail Erol, Mark S. Hunter, Esra Ayan, Berna Dogan, Mengning Liang, Busecan Aksoydan, A. Batyuk, Ozgur Can, Cengizhan Buyukdag, Sabri O. Besler, Seyma Calis, Brandon Hayes, Matthew Seaberg, Serena Ozabrahamyan, Ilayda Tolu, Gihan K. Ketawala, Anton Barty, Raymond G. Sierra, Kader Sahin, Gokhan Tanisali, Oktay Gocenler, Ali D. Yucel, E. Han Dao, Alpsu Olkan, Ayse B. Peksen, Zhen Su, A. Tolstikova, Sabine Botha, Busra Yuksel, Fatma Betul Ertem

المساهمون: Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Dağ, Çağdaş, Yığın, Merve, Büyükdağ, Cengizhan, Ertem, Fatma Betül, Yıldırım, Günseli, Destan, Ebru, Güven, Ömür, Ayan, Esra, Yüksel, Büşra, Pekşen, Ayşe Buket, Göçenler, Oktay, Yücel, Ali Doğa, Can, Özgür, Ozabrahamyan, Serena, Shafiei, Alaleh, Akşit, Fulya, Tanısalı, Gökhan, Besler, Sabri Özkan, Durdağı, Serdar, Doğan, Berna, Avşar, Timuçin, Erol, İsmail, Çalış, Şeyma, Orhan, Müge D., Aksoydan, Busecan, Şahin, Kader, Oktay, Lalehan, Tolu, İlayda, Olkan, Alpsu, Erdemoğlu, Ece, Yefanov, Oleksandr M., Dao, E. Han, Hayes, Brandon, Liang, Mengning, Seaberg, Matthew H., Hunter, Mark S., Batyuk, Alex, Mariani, Valerio, Su, Zhen, Poitevin, Frederic, Yoon, Chun Hong, Kupitz, Christopher, Sierra, Raymond G., Snell, Edward H., Koç Üniversitesi İş Bankası Enfeksiyon Hastalıkları Uygulama ve Araştırma Merkezi (EHAM) / Koç University İşbank Center for Infectious Diseases (KU-IS CID), College of Sciences, Graduate School of Sciences and Engineering, School of Nursing, Department of Molecular Biology and Genetics, Department of Chemical and Biological Engineering, Department of Materials Science and Engineering

المصدر: Structure 29(12), 1382-1396.e6 (2021). doi:10.1016/j.str.2021.07.007
Structure
Structure (London, England : 1993)

مصطلحات موضوعية: Drug, Molecular model, Protein Conformation, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), media_common.quotation_subject, medicine.medical_treatment, ambient temperature, Molecular Conformation, Crystallography, X-Ray, Article, Structural Biology, Catalytic Domain, medicine, SFX, Computer Simulation, Molecular Biology, Coronavirus 3C Proteases, media_common, Principal Component Analysis, Protease, Biochemistry and molecular biology, Biophysics, Cell biology, biology, drug repurposing, Drug discovery, SARS-CoV-2, Drug Repositioning, Temperature, Active site, Small molecule, Recombinant Proteins, COVID-19 Drug Treatment, Molecular Docking Simulation, Drug repositioning, Crystallography, main protease, Drug Design, ddc:540, biology.protein, Dimerization, Ambient temperature, Drug repurposing, Main protease

وصف الملف: text/academic publication

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392e9ce96ee7ee4a53bb651f21b45fef
https://bib-pubdb1.desy.de/record/462438

10

Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing

المؤلفون: Christopher Kupitz, Oleksandr Yefanov, Ilayda Tolu, Berna Dogan, Chun Hong Yoon, A. Tolstikova, Sabri O. Besler, Edward H. Snell, Busra Yuksel, Ismail Erol, Mark S. Hunter, Merve Yigin, Lalehan Oktay, Fulya Aksit, Çağdaş Dağ, Ece Erdemoglu, Brandon Hayes, Betul Ertem, Raymond G. Sierra, Omur Guven, Seyma Calis, Alaleh Shafiei, Zhen Su, Serena Ozabrahamyan, Oktay Gocenler, Gihan K. Ketawala, A. Batyuk, Valerio Mariani, Gunseli Yildirim, Kader Sahin, Esra Ayan, Ozgur Can, Cengizhan Buyukdag, Busecan Aksoydan, Mengning Liang, Frédéric Poitevin, Gokhan Tanisali, Alpsu Olkan, E. Han Dao, Ayse B. Peksen, Anton Barty, Sabine Botha, Ali D. Yucel, Matthew Seaberg, Serdar Durdagi, Ebru Destan, Muge Didem Orhan, Hasan DeMirci, Timucin Avsar

مصطلحات موضوعية: Drug, Protease, biology, Molecular model, Chemistry, media_common.quotation_subject, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine.medical_treatment, Active site, Computational biology, Small molecule, Drug repositioning, Structural biology, biology.protein, medicine, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6806eaa683664b89448ef04416faa1d9
https://doi.org/10.1101/2020.09.09.287987

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