المؤلفون: Esmailnejad A; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Zununi Vahed S; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Hejazian SM; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Aslanabadi N; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Lotfollahhi Gharakhanlu H; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Saraei M; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Ahmadzadehpournaky A; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Ardalan K; School of Pharmacy and Pharmaceutical Sciences, Islamic Azad University, Teheran, Iran., Ardalan M; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Ghaffari Bavil S; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

المصدر: Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Aug; Vol. 12 (4), pp. e1228.

نوع المنشور: Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 101626369 Publication Model: Print Cited Medium: Internet ISSN: 2052-1707 (Electronic) Linking ISSN: 20521707 NLM ISO Abbreviation: Pharmacol Res Perspect Subsets: MEDLINE

مواضيع طبية MeSH: Edaravone*/therapeutic use , Edaravone*/administration & dosage , Contrast Media*/adverse effects , Coronary Angiography*/adverse effects, Humans ; Double-Blind Method ; Male ; Female ; Middle Aged ; Aged ; Free Radical Scavengers/therapeutic use ; Free Radical Scavengers/administration & dosage ; Creatinine/blood ; Kidney Diseases/chemically induced ; Kidney Diseases/prevention & control ; Antipyrine/analogs & derivatives ; Antipyrine/therapeutic use ; Treatment Outcome

المؤلفون: Chen W; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, No.68 Changle Road, Nanjing, 210006, China., Zhang H; Department of Neurology, the Fourth Affiliated Hospital of Nanjing Medical University, No.298 Nanpu Road, Nanjing, 210000, China., Li Z; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, No.68 Changle Road, Nanjing, 210006, China., Deng Q; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, No.68 Changle Road, Nanjing, 210006, China., Wang M; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, No.68 Changle Road, Nanjing, 210006, China. 15895826278@163.com., Chen Y; Department of Ultrasound Medicine, Nanjing First Hospital, Nanjing Medical University, No.68 Changle Road, Nanjing, 210006, China. 398417695@qq.com., Zhang Y; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, No.68 Changle Road, Nanjing, 210006, China. 18951670202@163.com.

المصدر: BMC neurology [BMC Neurol] 2024 Jun 20; Vol. 24 (1), pp. 209. Date of Electronic Publication: 2024 Jun 20.

نوع المنشور: Clinical Trial; Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968555 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2377 (Electronic) Linking ISSN: 14712377 NLM ISO Abbreviation: BMC Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Edaravone*/therapeutic use , Edaravone*/administration & dosage , Edaravone*/pharmacology , Ischemic Stroke*/drug therapy, Aged ; Female ; Humans ; Male ; Middle Aged ; Cytokines/metabolism ; Inflammation/drug therapy ; Neuroprotective Agents/therapeutic use ; Neuroprotective Agents/administration & dosage ; Treatment Outcome

المؤلفون: He Y; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China., Zhang M; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China., Gong X; Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China.; Clinical Medical Research Center for Stroke Prevention and Treatment of Hunan Province, Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China., Liu X; Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China.; Clinical Medical Research Center for Stroke Prevention and Treatment of Hunan Province, Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China., Zhou F; Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China.; Clinical Medical Research Center for Stroke Prevention and Treatment of Hunan Province, Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China., Yang B; Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China.; Clinical Medical Research Center for Stroke Prevention and Treatment of Hunan Province, Department of Neurology, the Second Xiangya Hospital, Central South University, Changsha 410083, China.

المصدر: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Aug 07; Vol. 16 (31), pp. 40739-40752. Date of Electronic Publication: 2024 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE

مواضيع طبية MeSH: Silicon Dioxide*/chemistry , Cerebral Hemorrhage*/drug therapy , Cerebral Hemorrhage*/pathology , Reactive Oxygen Species*/metabolism , Nanoparticles*/chemistry , Edaravone*/chemistry , Edaravone*/pharmacology , Indoles*/chemistry , Indoles*/pharmacology, Animals ; Mice ; Porosity ; Polymers/chemistry ; Polymers/pharmacology ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/pharmacology ; Male ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Oxidative Stress/drug effects

المؤلفون: Zeng S; Harbin Medical University Graduate School, Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Li Y; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Yao Z; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Li Y; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Cao Y; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Wen L; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Li M; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China., Zheng J; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China. Electronic address: icuzhengjunbo@126.com., Wang H; Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150086, China. Electronic address: icuwanghongliang@163.com.

المصدر: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2024 Aug; Vol. 126, pp. 270-283. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article; Meta-Analysis; Review

بيانات الدورية: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 9433352 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2653 (Electronic) Linking ISSN: 09675868 NLM ISO Abbreviation: J Clin Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Hyperbaric Oxygenation*/methods , Edaravone*/therapeutic use , Carbon Monoxide Poisoning*/complications , Carbon Monoxide Poisoning*/therapy, Humans ; Combined Modality Therapy/methods ; Brain Diseases/etiology ; Brain Diseases/therapy ; Randomized Controlled Trials as Topic ; Free Radical Scavengers/therapeutic use

المؤلفون: Yang R; North Sichuan Medical College, Nanchong, Sichuan, China; Department of Neurology, Xichang People's Hospital, Xichang, Sichuan, China., Li J; North Sichuan Medical College, Nanchong, Sichuan, China., Zhao L; North Sichuan Medical College, Nanchong, Sichuan, China., Zhang M; North Sichuan Medical College, Nanchong, Sichuan, China., Qin Y; North Sichuan Medical College, Nanchong, Sichuan, China., Tong X; Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China., Wang S; North Sichuan Medical College, Nanchong, Sichuan, China., Yang F; Department of Nuclear Medicine, Affiliated Hospital of North Sichuan Medical College; North Sichuan Medical College, Nanchong, Sichuan, China., Jiang G; Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China. Electronic address: neurodoctor@163.com.

المصدر: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2024 Jul; Vol. 33 (7), pp. 107738. Date of Electronic Publication: 2024 May 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Saunders Country of Publication: United States NLM ID: 9111633 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8511 (Electronic) Linking ISSN: 10523057 NLM ISO Abbreviation: J Stroke Cerebrovasc Dis Subsets: MEDLINE

مواضيع طبية MeSH: Edaravone*/pharmacology , Disease Models, Animal* , Rats, Sprague-Dawley* , Neuroprotective Agents*/pharmacology , Interleukin-1beta*/metabolism , Brain Edema*/pathology , Brain Edema*/drug therapy , Brain Edema*/metabolism , Brain Edema*/enzymology , Brain Edema*/prevention & control, Animals ; Male ; 4-Aminobutyrate Transaminase/metabolism ; 4-Aminobutyrate Transaminase/antagonists & inhibitors ; Behavior, Animal/drug effects ; Cerebral Hemorrhage/drug therapy ; Cerebral Hemorrhage/metabolism ; Cerebral Hemorrhage/pathology ; Cerebral Hemorrhage/enzymology ; Anti-Inflammatory Agents/pharmacology ; Cognition/drug effects ; Brain/drug effects ; Brain/pathology ; Brain/metabolism ; Brain/enzymology ; Nitric Oxide Synthase Type II/metabolism ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Inflammation Mediators/metabolism

المؤلفون: Guo H; Department of Neurology, First Hospital, Shanxi Medical University, Taiyuan,China; First Clinical Medical College, Shanxi Medical University, Taiyuan, China., Li H; Department of Neurology, First Hospital, Shanxi Medical University, Taiyuan,China; First Clinical Medical College, Shanxi Medical University, Taiyuan, China., Jia Z; Department of Neurology, First Hospital, Shanxi Medical University, Taiyuan,China; First Clinical Medical College, Shanxi Medical University, Taiyuan, China., Ma S; Department of Neurology, First Hospital, Shanxi Medical University, Taiyuan,China; First Clinical Medical College, Shanxi Medical University, Taiyuan, China., Zhang J; Department of Neurology, First Hospital, Shanxi Medical University, Taiyuan,China. Electronic address: zhj6929@139.com.

المصدر: Brain research [Brain Res] 2024 Jun 15; Vol. 1833, pp. 148917. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

مواضيع طبية MeSH: Dementia, Vascular*/drug therapy , Dementia, Vascular*/metabolism , Oxidative Stress*/drug effects , Rats, Sprague-Dawley* , Edaravone*/pharmacology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/metabolism , Hippocampus*/metabolism , Hippocampus*/drug effects , Receptors, N-Methyl-D-Aspartate*/metabolism , Signal Transduction*/drug effects , Disease Models, Animal*, Animals ; Rats ; Male ; Neuroprotective Agents/pharmacology ; Inflammation/metabolism ; Inflammation/drug therapy

المؤلفون: Huang SL; Department of Acupuncture, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu City, China., Shen YL; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, No. 1166 Liutai Avenue, Wenjiang District, Chengdu City, 610000, China., Peng WY; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, No. 1166 Liutai Avenue, Wenjiang District, Chengdu City, 610000, China., Ye K; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, No. 1166 Liutai Avenue, Wenjiang District, Chengdu City, 610000, China., Zheng H; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, No. 1166 Liutai Avenue, Wenjiang District, Chengdu City, 610000, China. zhenghui@cdutcm.edu.cn.

المصدر: Acta neurologica Belgica [Acta Neurol Belg] 2024 Jun; Vol. 124 (3), pp. 895-904. Date of Electronic Publication: 2024 Feb 12.

نوع المنشور: Systematic Review; Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Springer Country of Publication: Italy NLM ID: 0247035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2240-2993 (Electronic) Linking ISSN: 03009009 NLM ISO Abbreviation: Acta Neurol Belg Subsets: MEDLINE

مواضيع طبية MeSH: Edaravone*/therapeutic use , Amyotrophic Lateral Sclerosis*/drug therapy, Humans ; Free Radical Scavengers/therapeutic use ; Randomized Controlled Trials as Topic/methods ; Treatment Outcome

المؤلفون: Wang J; Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China., Du L; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China., Zhang T; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China., Chu Y; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China., Wang Y; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China., Wang Y; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China., Ji X; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China., Kang Y; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China., Cui R; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China., Zhang G; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China., Liu J; Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China., Shi G; Laboratory of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China; Neuroscience Research Center, Hebei Medical University, Shijiazhuang, 050017, China. Electronic address: shigeming@hebmu.edu.cn.

المصدر: Neuropharmacology [Neuropharmacology] 2024 Sep 01; Vol. 255, pp. 110006. Date of Electronic Publication: 2024 May 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

مواضيع طبية MeSH: Toll-Like Receptor 4*/metabolism , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/metabolism , Receptors, Immunologic*/metabolism , Receptors, Immunologic*/genetics , Membrane Glycoproteins*/metabolism , Edaravone*/pharmacology , Edaravone*/therapeutic use , Up-Regulation*/drug effects, Animals ; Mice ; Male ; Mice, Transgenic ; Neuroprotective Agents/pharmacology ; MAP Kinase Signaling System/drug effects ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Mice, Inbred C57BL ; Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Disease Models, Animal ; Presenilin-1/genetics

المؤلفون: Li Y; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., He J; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., Luo B; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., Yu Q; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., Cai T; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., Li Y; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., Fan L; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China., Zhou X; Department of Pharmacy, the, Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, 550003, P. R. China., Tang L; State Key Laboratory of Functions and Applications of Medicinal Plants, College of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, P. R. China.

المصدر: Chemistry & biodiversity [Chem Biodivers] 2024 May; Vol. 21 (5), pp. e202400110. Date of Electronic Publication: 2024 Apr 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

مواضيع طبية MeSH: Edaravone*/pharmacology , Edaravone*/chemistry , Ischemic Stroke*/drug therapy , Ischemic Stroke*/metabolism , Ischemic Stroke*/pathology , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemistry , Platelet Aggregation Inhibitors*/chemical synthesis , Platelet Aggregation*/drug effects , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/chemistry , Neuroprotective Agents*/chemical synthesis, Animals ; Rats ; Molecular Docking Simulation ; Male ; Mice ; Molecular Structure ; Structure-Activity Relationship ; Rats, Sprague-Dawley ; Drug Discovery ; Pyridazines/pharmacology ; Pyridazines/chemistry ; Oxidative Stress/drug effects

المؤلفون: Singh P; Cogent Biosciences, Waltham, MA., Belliveau P; Massachusetts College of Pharmacy and Health Sciences, School of Pharmacy, Manchester, NH; and., Towle J; Massachusetts College of Pharmacy and Health Sciences, School of Pharmacy, Manchester, NH; and., Neculau AE; Faculty of Medicine, Transilvania University of Brasov, Brasov, Romania., Dima L; Faculty of Medicine, Transilvania University of Brasov, Brasov, Romania.

المصدر: American journal of therapeutics [Am J Ther] 2024 May-Jun 01; Vol. 31 (3), pp. e258-e267.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9441347 Publication Model: Print Cited Medium: Internet ISSN: 1536-3686 (Electronic) Linking ISSN: 10752765 NLM ISO Abbreviation: Am J Ther Subsets: MEDLINE

مواضيع طبية MeSH: Edaravone*/administration & dosage , Edaravone*/pharmacology , Edaravone*/therapeutic use , Amyotrophic Lateral Sclerosis*/drug therapy , Neuroprotective Agents*/administration & dosage , Neuroprotective Agents*/therapeutic use , Neuroprotective Agents*/adverse effects, Humans ; Administration, Oral ; Suspensions ; Biological Availability