المؤلفون: Toyin Mohammed, Salman, Isiaka Abdullateef, Alagbonsi, Sheu Oluwadare, Sulaiman

المصدر: Metabolism Open

مصطلحات موضوعية: Plasma glucose, LDH, Lactate dehydrogenase, ANOVA, Analysis of Variance, G6P, Glucose-6-phosphate, Telfairia occidentalis, SEM, Standard error of mean, Counter-regulatory hormones, LSD, Least Significance Difference, NAD, Nicotinamide adenine dinucleotide, G6Pase, Glucose-6-phosphatase, Original Research Paper, Glucoregulatory enzymes, GCK, Glucokinase, TO, Telfairia occidentalis, NIH, National Institutes of Health, ELISA, Enzyme-linked immunosorbent assay, Avidin-HRP, Avidin-Horseradish Peroxidase, EGP, Endogenous glucose production, Insulin, G6PD, Glucose-6-phosphate dehydrogenase, SPSS, Statistical Package for the Social Sciences, cAMP, Cyclic adenosine monophosphate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::233c973b9d0484b645de539d1e86c2df
https://pubmed.ncbi.nlm.nih.gov/33235989

المؤلفون: Nancy Antoine, Lucie Ruiz, Holger Klein, Patrick Gilon, Anne Wojtusciszyn, Fiona M. Gribble, Frank Reimann, Robert Augustin, Bao-Khanh Lai, Bilal Singh, Michael P. Pieper, Eva Gatineau, Nano Rita, Mohammed Bensellam, Pedro Luis Herrera, Birgit Stierstorfer, Firas Khattab, Heeyoung Chae, Lorenzo Piemonti, Davide Brusa, Michael Mark, Eric Mayoux, Christophe Broca

المساهمون: Université Catholique de Louvain = Catholic University of Louvain (UCL), Boehringer Ingelheim Pharma GmbH & Co. KG, University of Geneva [Switzerland], Addenbrooke's Hospital, Cambridge University NHS Trust, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Lausanne University Hospital, IRCCS Ospedale San Raffaele [Milan, Italy], Chae, Heeyoung, Augustin, Robert, Gatineau, Eva, Mayoux, Eric, Bensellam, Mohammed, Antoine, Nancy, Khattab, Fira, Lai, Bao-Khanh, Brusa, Davide, Stierstorfer, Birgit, Klein, Holger, Singh, Bilal, Ruiz, Lucie, Pieper, Michael, Mark, Michael, Herrera, Pedro L, Gribble, Fiona M, Reimann, Frank, Wojtusciszyn, Anne, Broca, Christophe, Rita, Nano, Piemonti, Lorenzo, Gilon, Patrick, Gribble, Fiona [0000-0002-4232-2898], Reimann, Frank [0000-0001-9399-6377], Apollo - University of Cambridge Repository

المصدر: Molecular Metabolism
Molecular metabolism, vol. 42, pp. 101071
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101071. ⟨10.1016/j.molmet.2020.101071⟩
Molecular Metabolism (2020) P. 101071
Molecular Metabolism, Vol 42, Iss, Pp 101071-(2020)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, medicine.medical_treatment, IC50, half maximal inhibitory concentration, SGLT2i, sodium-glucose cotransporter 2 inhibitors, MESH: Insulin Secretion, MESH: Glucosides, MESH: Insulin-Secreting Cells, chemistry.chemical_compound, Mice, αMG, α-methyl-D-glucopyranoside, EGP, endogenous glucose production, 0302 clinical medicine, Glucosides, Glucagon-Like Peptide 1, Insulin-Secreting Cells, FACS, fluorescence-activated cell sorting, Insulin Secretion, Insulin, ddc:576.5, MESH: Animals, Dapagliflozin, geography.geographical_feature_category, Chemistry, MESH: Glucagon, BW, body weight, Diabetes, SGLT2 inhibitor, MESH: Pancreas, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Islet, 3. Good health, SGLT, sodium-glucose cotransporter, MESH: Glucose, MESH: Sodium-Glucose Transporter 2, No direct effect of SGLT2i on α- and β-cells, MESH: Sodium-Glucose Transporter 2 Inhibitors, Ketone bodies, Original Article, medicine.medical_specialty, lcsh:Internal medicine, endocrine system, MESH: Rats, 030209 endocrinology & metabolism, MESH: Insulin, Glucagon, 03 medical and health sciences, Islets of Langerhans, Gliflozins, TPM, transcripts per million, Sodium-Glucose Transporter 2, G, glucose, In vivo, Internal medicine, Empagliflozin, medicine, MESH: Benzhydryl Compounds, Animals, Humans, Benzhydryl Compounds, lcsh:RC31-1245, Molecular Biology, MESH: Mice, Pancreas, Sodium-Glucose Transporter 2 Inhibitors, geography, MESH: Humans, MESH: Islets of Langerhans, Glucose transporter, MESH: Glucagon-Like Peptide 1, Cell Biology, Rats, 030104 developmental biology, Endocrinology, Glucose, Glucagon-Secreting Cells, MESH: Blood Glucose, MESH: Glucagon-Secreting Cells, Cmax, maximum serum concentration, diabetes, glucagon, insulin

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13201cec4df0020051e57406d53b494a
https://pubmed.ncbi.nlm.nih.gov/32896668

المؤلفون: Mayumi Nagashimada, Eric Mayoux, Naoto Nagata, Guanliang Chen, Liang Xu, Shuichi Kaneko, Yinhua Ni, Fen Zhuge, Tsuguhito Ota

المصدر: EBioMedicine
EBioMedicine, Vol 20, Iss C, Pp 137-149 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, FGF21, Macrophage, lcsh:Medicine, AST, aspartate aminotransferase, White adipose tissue, 030204 cardiovascular system & hematology, ATMs, adipose tissue macrophages, Brown adipose tissue, EGP, endogenous glucose production, Mice, 0302 clinical medicine, Glucosides, FACS, fluorescence-activated cell sorting, TBARS, thiobarbituric acid reactive substances, Empa, empagliflozin, RER, respiratory exchange ratio, Adiposity, lcsh:R5-920, Glucose tolerance test, medicine.diagnostic_test, NEFA, non-esterified fatty acid, Fatty Acids, CT, computed tomographic, WAT, white adipose tissue, DIO, high-fat-diet-induced obese, General Medicine, TG, triglycerides, Adipose Tissue, H&E, haematoxylin and eosin, GTT, glucose tolerance test, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Adipose tissue macrophages, Biology, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Insulin resistance, VCO2, carbon dioxide production, FGF21, fibroblast growth factor, Internal medicine, UCP1, uncoupling protein 1, medicine, Empagliflozin, Animals, Hypoglycemic Agents, Obesity, Benzhydryl Compounds, Muscle, Skeletal, Sodium-Glucose Transporter 2 Inhibitors, ITT, insulin tolerance test, VO2, oxygen consumption, Inflammation, Macrophages, lcsh:R, SGLT, sodium/glucose cotransporter, Sodium glucose cotransporter-2 inhibitor, Body Weight, Insulin tolerance test, ALT, Alanine aminotransferase, Energy metabolism, UGE, urinary glucose excretion, Macrophage Activation, medicine.disease, BAT, brown adipose tissue, TC, total cholesterol, Fatty Liver, AMPK, AMP-activated protein kinase, Glucose, 030104 developmental biology, Endocrinology, Insulin Resistance, LMs, liver macrophages, Diet-induced obese, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c85fd9e3671e9effaeef0acf4b89dd1
https://doi.org/10.1016/j.ebiom.2017.05.028

المؤلفون: Hartmut Ruetten, Sebastian Brachs, Dieter Schmoll, Bodo Brunner, Joachim Spranger, Angelika F. Winkel, Kerstin Jahn-Hofmann, Andreas L. Birkenfeld, Hui Tang, Daniel Margerie

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 11, Pp 1072-1082 (2016)

مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Steatosis, p, perirenal, Lipid accumulation, White adipose tissue, SKM, skeletal muscle, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit, WD, western diet, chemistry.chemical_compound, EGP, endogenous glucose production, GIR, glucose infusion rate, Mice, INDY/Slc13a5, Non-alcoholic Fatty Liver Disease, Citrate transport, IEX, anion-exchange high-performance liquid chromatography, Citrates, 2-DG, 2-Deoxy-d-glucose, RER, respiratory exchange ratio, Dicarboxylic Acid Transporters, mINDY, Slc13a5/SLC13A5, Symporters, Fatty liver, WAT, white adipose tissue, siINDY, mINDY-specific siRNA, Original Article, RNA Interference, e, epididymal, medicine.medical_specialty, lcsh:Internal medicine, TCA, tricarboxylic acid, Biology, INDY, ‘I'm not dead Yet’, Citric Acid, 03 medical and health sciences, SCR, non-silencing scrambled control siRNA, Insulin resistance, s, subcutaneous, FLD, fatty liver disease, Internal medicine, medicine, Animals, lcsh:RC31-1245, Molecular Biology, KO, knockout, Triglyceride, solute carrier family 13, member 5, EE, energy expenditure, Lipid metabolism, Cell Biology, HE clamp, hyperinsulinemic-euglycemic clamp, medicine.disease, Lipid Metabolism, Diet, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, FA, fatty acids, siRNA, ORO, oil red O, 2-Deoxy-D-glucose, T2D, type-2 diabetes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387a0397cf560df92007d51d7e2ffd73

المؤلفون: Wouter D. van Marken Lichtenbelt, Gert Schaart, Bas Havekes, Marie-Fleur Habets, Emmani B.M. Nascimento, Yvonne M. H. Bruls, Vera B. Schrauwen-Hinderling, Esther Moonen-Kornips, Marlies de Ligt, Patrick Schrauwen, Jan Petter Hansen

المساهمون: RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, Promovendi NTM, Humane Biologie, Beeldvorming, RS: NUTRIM - R1 - Metabolic Syndrome, Interne Geneeskunde, MUMC+: MA Endocrinologie (9), Ondersteunend personeel NTM, Nutrition and Movement Sciences, MUMC+: DA BV Klinisch Fysicus (9)

المصدر: Molecular Metabolism
Molecular Metabolism, 12, 39-47. Elsevier
Molecular Metabolism, Vol 12, Iss, Pp 39-47 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, SUV, standard uptake value, endocrine system diseases, Glucose uptake, OGTT, oral glucose tolerance test, IHL, intrahepatic lipid, OXPHOS, oxidative phosphorylation, Type 2 diabetes, Ra, glucose appearance, Resveratrol, LIPID-CONTENT, Brown adipose tissue, IMCL, intramyocellular lipid content, UCP1, uncoupling protein, SUPPLEMENTATION, chemistry.chemical_compound, MELLITUS, EGP, endogenous glucose production, Rd, glucose disposal, 0302 clinical medicine, Adipose Tissue, Brown, OBESE HUMANS, FDR, first-degree relatives, PCr, phosphocreatine, skin and connective tissue diseases, MOG, malate + octanoyl-carnitine + glutamate, METABOLIC SYNDROME, Fatty Acids, food and beverages, MEN, WAT, white adipose tissue, RANDOMIZED CONTROLLED-TRIAL, MUSCLE, Middle Aged, Insulin sensitivity, 3. Good health, Pedigree, medicine.anatomical_structure, MGS, malate + glutamate + succinate, Original Article, Pre-diabetes, hormones, hormone substitutes, and hormone antagonists, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, lcsh:Internal medicine, medicine.medical_specialty, DHR, dihydro-resveratrol, SIRT1, sirtuin 1, CONTROLLED CLINICAL-TRIAL, 030209 endocrinology & metabolism, T2D, type 2 diabetes, 03 medical and health sciences, Insulin resistance, MOG, malate + octanoyl-carnitine + glutamate + succinate, Internal medicine, medicine, Humans, Hypoglycemic Agents, First-degree relatives, MG, malate + glutamate, lcsh:RC31-1245, Molecular Biology, F-FDG, fluoro-deoxy-glucose, Aged, business.industry, organic chemicals, MO, malate + octanoyl-carnitine, Cell Biology, MRS, magnetic resonance spectroscopy, medicine.disease, Mitochondria, Muscle, BAT, brown adipose tissue, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, Glucose, chemistry, Diabetes Mellitus, Type 2, GLUCOSE-TOLERANCE, Metabolic syndrome, Insulin Resistance, Mitochondrial function, business, Ex vivo, NE, norepinephrine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6b567b696180405d69a1decae8f901
https://pubmed.ncbi.nlm.nih.gov/29706321

المؤلفون: Gidon J. Bönhof, Daniel F. Markgraf, Jesper Lundbom, Dan Ziegler, Kevin G Murphy, Alessandra Bierwagen, Erifili Hatziagelaki, Michael Roden, Sofiya Gancheva

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 7, Iss, Pp 71-79 (2018)
Molecular metabolism, 7:71-79

مصطلحات موضوعية: Male, LF, low-frequency, medicine.medical_treatment, Stimulation, Parasympathetic nervous system, EGP, endogenous glucose production, 0302 clinical medicine, Adenosine Triphosphate, Heart Rate, Medicine, Glucose homeostasis, ANOVA, analysis of variance, Fasting, Middle Aged, medicine.anatomical_structure, Liver, Original Article, Female, Hepatic energy metabolism, Hepatic insulin sensitivity, Vagus nerve stimulation, Liver fat content, Adult, medicine.medical_specialty, lcsh:Internal medicine, ATP, adenosine triphosphate, taVNS, transcutaneous auricular vagus nerve stimulation, PP, pancreatic polypeptide, HF, high-frequency, 030209 endocrinology & metabolism, Carbohydrate metabolism, HRV, heart rate variability, Glucagon, Pi, inorganic phosphate, HCL, liver fat content, 03 medical and health sciences, Parasympathetic Nervous System, Internal medicine, Heart rate, Humans, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Cell Biology, MRS, magnetic resonance spectroscopy, Vagus nerve, NTS, nucleus tractus solitarii, Endocrinology, Glucose, business, Energy Metabolism, 030217 neurology & neurosurgery, BRS, baroreflex sensitivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9676e712d6719c40c87bcf4a725a9ddc
http://hdl.handle.net/10044/1/54143

المؤلفون: Depei Li, Feng Li, Xuemei Shi, Shaji Chacko, Lawrence Chan, Douglas G. Burrin, Xinfu Guan

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1350-1359 (2017)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Glucagon-like peptides, Endogenous glucose production, ChAT, choline acetyltransferase, Endogeny, Enteroendocrine cell, CNO, clozapine N-oxide, ipGTT, intraperitoneal glucose tolerance test, Proglucagon, Mice, EGP, endogenous glucose production, GIR, glucose infusion rate, Glucagon-Like Peptide 1, Gcg, glucagon, Receptors, Glucagon, Glucose homeostasis, Homeostasis, Insulin, Neurons, Glucose tolerance test, medicine.diagnostic_test, Insulin sensitivity, 3. Good health, aCSF, artificial cerebrospinal fluid, AP, area postrema, medicine.anatomical_structure, GLP-2R (or Glp2r), GLP-2 receptor, icv, intracerebroventricular, DMH, the dorsomedial hypothalamic nuclei, Original Article, lcsh:Internal medicine, medicine.medical_specialty, DREADD, Designer Receptors Exclusively Activated by Designer Drugs, Mice, Transgenic, DMV, dorsal motor vagal nucleus, HGP, hepatic glucose production, Biology, GNG, gluconeogenesis, PPG, preproglucagon, Glucagon, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Glucagon-Cre mice, Internal medicine, medicine, Animals, GLP-1/2, glucagon-like peptides, lcsh:RC31-1245, Molecular Biology, GLP-1R (or Glp1r), GLP-1 receptor, Preproglucagon neurons, CC, central canal, NTS, the nucleus of the solitary tract, Gluconeogenesis, DVC, the brainstem dorsal vagal complex, Cell Biology, Glucose Tolerance Test, ARC, the arcuate nucleus, PVH, the paraventricular hypothalamic nuclei, 030104 developmental biology, Endocrinology, Glucose, Basal (medicine), Neuron, sense organs, Insulin Resistance, Energy Metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf31c31b1dac4a6b564ef6ec833285c
https://pubmed.ncbi.nlm.nih.gov/29107283

المؤلفون: Kasper W. ter Horst, Pim W. Gilijamse, Ahmet Demirkiran, Max Nieuwdorp, Joanne Verheij, Mariëtte T. Ackermans, Mireille J. Serlie, Bart A. van Wagensveld, Johannes A. Romijn, Mark A. Herman, Eleftheria Maratos-Flier

المساهمون: Graduate School, Other Research, Laboratory for Endocrinology, Pathology, General Internal Medicine, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology Endocrinology Metabolism, Vascular Medicine, Endocrinology, ACS - Diabetes & metabolism, Internal medicine

المصدر: Molecular metabolism, 6(11), 1493-1502. Elsevier GmbH
Molecular Metabolism, 6(11), 1493-1502. Elsevier GmbH
ter Horst, K W, Gilijamse, P W, Demirkiran, A, van Wagensveld, B A, Ackermans, M T, Verheij, J, Romijn, J A, Nieuwdorp, M, Maratos-Flier, E, Herman, M A & Serlie, M J 2017, ' The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans ', Molecular Metabolism, vol. 6, no. 11, pp. 1493-1502 . https://doi.org/10.1016/j.molmet.2017.08.014
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1493-1502 (2017)

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, FGF21, medicine.medical_treatment, Bariatric Surgery, FGF21, fibroblast growth factor 21, AUC, area under the curve, EGP, endogenous glucose production, chemistry.chemical_compound, 0302 clinical medicine, Weight loss, Insulin, Middle Aged, Fructose Intolerance, Obesity, Morbid, Liver, Female, Original Article, medicine.symptom, Rd, rate of disappearance, Adult, lcsh:Internal medicine, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ChREBP, carbohydrate response element-binding protein, GLP1, glucagon-like peptide 1, NASH, non-alcoholic steatohepatitis, Gastric Bypass, Translational study, 030209 endocrinology & metabolism, Fructose, Biology, 03 medical and health sciences, Insulin resistance, Internal medicine, Weight Loss, FFA, free fatty acid, medicine, Humans, Obesity, lcsh:RC31-1245, Carbohydrate-responsive element-binding protein, Molecular Biology, IQR, interquartile range, Ra, rate of appearance, Cell Biology, medicine.disease, Fatty Liver, Fibroblast Growth Factors, Glucose, 030104 developmental biology, Endocrinology, chemistry, Hyperinsulinemic-euglycemic clamp, Energy Metabolism, SD, standard deviation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2e659739c9955525826cd9525c9c29
https://pure.amc.nl/en/publications/the-fgf21-response-to-fructose-predicts-metabolic-health-and-persists-after-bariatric-surgery-in-obese-humans(1b1e6aa9-0f4a-4f37-b984-a10e3cf4e1ba).html

المؤلفون: Mogens Vyberg, Susanne Keiding, Michael F. Nielsen, Niels Møller, Kathrine Brodersen, Klaus Roelsgaard, Hendrik Vilstrup

المصدر: Nielsen, M F, Roelsgaard, K, Keiding, S, Brodersen, K, Møller, N, Vyberg, M & Vilstrup, H 2015, ' Impaired hepatic counterregulatory response to insulin-induced hypoglycemia in hepatic denervated pigs ', Journal of clinical & translational endocrinology, vol. 2, no. 4, pp. 131-136 . https://doi.org/10.1016/j.jcte.2015.08.004
Nielsen, M F, Roelsgaard, K, Keiding, S, Brodersen, K, Møller, N, Vyberg, M & Vilstrup, H 2015, ' Impaired hepatic counterregulatory response to insulin-induced hypoglycemia in hepatic denervated pigs ', Journal of Clinical & Translational Endocrinology, vol. 2, no. 4, pp. 131-136 . https://doi.org/10.1016/j.jcte.2015.08.004
Journal of Clinical & Translational Endocrinology, Vol 2, Iss 4, Pp 131-136 (2015)
Journal of Clinical & Translational Endocrinology

مصطلحات موضوعية: medicine.medical_specialty, Endogenous glucose production, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Endogeny, Hypoglycemia, Glucagon, lcsh:Diseases of the endocrine glands. Clinical endocrinology, Norepinephrine (medication), EGP, endogenous glucose production, Endocrinology, Internal medicine, medicine, Journal Article, Denervation, lcsh:RC648-665, business.industry, DN, denervated pigs, Insulin, medicine.disease, Hepatic innervation, Epinephrine, Somatostatin, Rd, rate of glucose utilization, business, Counterregulation, Research Paper, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be2f8ca03f8b3eecfd1cf5f12643ddb
https://pure.au.dk/portal/da/publications/impaired-hepatic-counterregulatory-response-to-insulininduced-hypoglycemia-in-hepatic-denervated-pigs(51d3bf06-f044-4ae1-9c9e-7c73c6e29fa5).html

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