المؤلفون: David E. Paschon, Stephanie Lussier, Tenzin Wangzor, Danny F. Xia, Patrick W. Li, Sarah J. Hinkley, Nicholas A. Scarlott, Stephen C. Lam, Adam J. Waite, Lynn N. Truong, Nimisha Gandhi, Bhakti N. Kadam, Deepak P. Patil, David A. Shivak, Gary K. Lee, Michael C. Holmes, Lei Zhang, Jeffrey C. Miller, Edward J. Rebar

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/52399a6682884a7196ea64923e436811

المؤلفون: Kai-Hsin Chang, Sarah E. Smith, Timothy Sullivan, Kai Chen, Qianhe Zhou, Jason A. West, Mei Liu, Yingchun Liu, Benjamin F. Vieira, Chao Sun, Vu P. Hong, Mingxuan Zhang, Xiao Yang, Andreas Reik, Fyodor D. Urnov, Edward J. Rebar, Michael C. Holmes, Olivier Danos, Haiyan Jiang, Siyuan Tan

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 4, Iss C, Pp 137-148 (2017)

مصطلحات موضوعية: genome editing, gene therapy, BCL11A, hemoglobinopathies, fetal hemoglobin, fetal globin reactivation, zinc finger nucleases, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050117300037; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/78e274bd1cdc4349b7f3df729d3543f4

المؤلفون: Tamara J. Laskowski, Yasmine Van Caeneghem, Rasoul Pourebrahim, Chao Ma, Zhenya Ni, Zita Garate, Ana M. Crane, Xuan Shirley Li, Wei Liao, Manuel Gonzalez-Garay, Jose Carlos Segovia, David E. Paschon, Edward J. Rebar, Michael C. Holmes, Dan Kaufman, Bart Vandekerckhove, Brian R. Davis

المصدر: Stem Cell Reports, Vol 7, Iss 2, Pp 139-148 (2016)

مصطلحات موضوعية: induced pluripotent stem cells, genome editing, immune deficiency, T cells, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671116300959; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/676abc2202b146eb97e086edfc92f229

المؤلفون: Benjamin L. Oakes, Danny F. Xia, Elizabeth F. Rowland, Denise J. Xu, Irina Ankoudinova, Jennifer S. Borchardt, Lei Zhang, Patrick Li, Jeffrey C. Miller, Edward J. Rebar, Marcus B. Noyes

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e66bba0eeef149b0809ce032052bdf58

المؤلفون: Ryan Forster, Kunitoshi Chiba, Lorian Schaeffer, Samuel G. Regalado, Christine S. Lai, Qing Gao, Samira Kiani, Henner F. Farin, Hans Clevers, Gregory J. Cost, Andy Chan, Edward J. Rebar, Fyodor D. Urnov, Philip D. Gregory, Lior Pachter, Rudolf Jaenisch, Dirk Hockemeyer

المصدر: Stem Cell Reports, Vol 2, Iss 6, Pp 838-852 (2014)

مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671114001428; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/29251974b44c49fb94543dca7d398aa3

المؤلفون: Christina Chaivorapol, Pascal Beauchesne, Rowena De Jesus, William E Dowdle, Xiaoyu Chen, Alison Bayley, Yunjiang Qiu, Andrew Birnberg, Yu Zheng, Antonino Montalbano, Angela Liu, Misbah Zafar, Karl Manner, Ramya Ankala, Eleonore Tham, Heer Shah, Ben Lam, Jaclyn Lock, Lindong Weng, Kate Watts, Amanda Valdiosera, Kimberly Davis, Lei Wang, Divy Kangeyan, PhD, Nicolas Devos, Athena Wong, Jason Lih, Edward J Rebar

المصدر: Blood. 140:1606-1607

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ba7c581e2312ccc468f7b6cbd40a6f2e
https://doi.org/10.1182/blood-2022-167627

المؤلفون: Xiaomeng Hu, Kathy White, Corie Gattis, Ryan Clarke, Sam Landry, Ron Basco, Eleonore Tham, Emily Luo, Andrew Tucker, Christopher Bandoro, Elaine Chu, Chi Young, Karl Manner, Priscilla Nho, Ben Lam, Pascal Beauchesne, Aaron Foster, William E. Dowdle, Edward J. Rebar, Terry J. Fry, Sonja Schrepfer

المصدر: Cancer Research. 82:5598-5598

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3da74a1da1f85fe790561b43db5502a0
https://doi.org/10.1158/1538-7445.am2022-5598

المؤلفون: Andreas Reik, Sarah J. Hinkley, Nicholas A. Scarlott, Deepak P. Patil, Yuri R. Bendana, David A. Shivak, Tenzin Wangzor, Stephen Lam, Yuanyue Zhou, David Paschon, Lei Zhang, Patrick Li, Friedrich Fauser, Gary Lee, Jeffrey C. Miller, Charles B Paine, Danny F Xia, Edward J. Rebar, Hunter W. Richards

المصدر: Nature Biotechnology. 37:945-952

مصطلحات موضوعية: T-Lymphocytes, Protein domain, Biomedical Engineering, Bioengineering, Locus (genetics), Computational biology, Cleavage (embryo), Applied Microbiology and Biotechnology, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Genome editing, Humans, RNA, Messenger, DNA Cleavage, 030304 developmental biology, Gene Editing, Zinc finger, 0303 health sciences, Base Sequence, biology, Chemistry, RNA, DNA, Flow Cytometry, Hematopoietic Stem Cells, Zinc finger nuclease, FokI, biology.protein, Molecular Medicine, K562 Cells, 030217 neurology & neurosurgery, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cc9ae3ffe9baf7fec7a19c03368407
https://doi.org/10.1038/s41587-019-0186-z

المؤلفون: Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao

المصدر: Nature Medicine. 25:1131-1142

مصطلحات موضوعية: 0301 basic medicine, Zinc finger, congenital, hereditary, and neonatal diseases and abnormalities, Mutant, General Medicine, Biology, medicine.disease, General Biochemistry, Genetics and Molecular Biology, nervous system diseases, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Huntington's disease, Transcription (biology), 030220 oncology & carcinogenesis, mental disorders, medicine, Gene silencing, Allele, Gene, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d19307c1ae395108f0cf1b74fb590fb6
https://doi.org/10.1038/s41591-019-0478-3

المؤلفون: Deepak P. Patil, Stephanie Lussier, Bhakti N. Kadam, Edward J. Rebar, Gary K. Lee, Stephen Lam, Sarah J. Hinkley, Jeffrey C. Miller, Lei Zhang, Lynn N. Truong, Danny F Xia, Michael C. Holmes, Patrick Li, Adam James Waite, David Paschon, Nimisha Gandhi, Nicholas A. Scarlott, David A. Shivak, Tenzin Wangzor

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Base pair, Computer science, Science, General Physics and Astronomy, Locus (genetics), 02 engineering and technology, Computational biology, Protein Engineering, Cleavage (embryo), Genome, Article, General Biochemistry, Genetics and Molecular Biology, Viral Proteins, 03 medical and health sciences, Transformation, Genetic, INDEL Mutation, Genome editing, Peptide Library, Escherichia coli, Humans, Genomic library, Deoxyribonucleases, Type II Site-Specific, Peptide library, lcsh:Science, Base Pairing, Gene Editing, Genomic Library, Multidisciplinary, Base Sequence, Genome, Human, DNA-Directed RNA Polymerases, General Chemistry, 021001 nanoscience & nanotechnology, Zinc finger nuclease, Zinc Finger Nucleases, 030104 developmental biology, Genetic Loci, lcsh:Q, K562 Cells, 0210 nano-technology, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f5828a9ddac31055e987d36ff42281
http://link.springer.com/article/10.1038/s41467-019-08867-x