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المؤلفون: Edward P. Garvey, S Thomas, M Atari, A D Sharp, R J Schotzinger, Peter Warn, C M Yates
المصدر: Medical Mycology. 58:505-513
مصطلحات موضوعية: Male, Antifungal Agents, Neutropenia, Pyridines, Tetrazoles, Microbial Sensitivity Tests, Pharmacology, Aspergillosis, Aspergillus fumigatus, Mice, 03 medical and health sciences, Therapeutic index, Pharmacokinetics, medicine, Animals, PK/PD models, 030304 developmental biology, Invasive Pulmonary Aspergillosis, 0303 health sciences, Aspergillus, Dose-Response Relationship, Drug, biology, 030306 microbiology, Chemistry, General Medicine, biology.organism_classification, medicine.disease, Disease Models, Animal, Infectious Diseases, 14-alpha Demethylase Inhibitors, Pharmacodynamics
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المؤلفون: Stephen J Page, John H. Rex, Lisa F. Shubitz, Edward P. Garvey, Karen Higgins, Neil M. Ampel, Yuliya Yasinskaya, David Angulo, Antonino Catanzaro, Kellie S. Reynolds, Janis E. Blair, Cheryl Dixon, Sunita J Shukla, David J Larwood, David A. Stevens, John N. Galgiani, Sumathi Nambiar, Rob Purdie, Royce H. Johnson, John J Farley, Jason N. Moore, Elizabeth O'Shaughnessy, Gareth Lewis
المصدر: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 74(11)
مصطلحات موضوعية: Microbiology (medical), medicine.medical_specialty, Government, Antifungal Agents, Coccidioidomycosis, biology, Coccidioides, business.industry, United States Food and Drug Administration, Standard treatment, Prevalence, Antifungal drug, Disease, medicine.disease, biology.organism_classification, United States, Valley fever, Infectious Diseases, Drug development, Family medicine, medicine, Humans, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6588b1d98e8a5f1807a413c0d50d9cf
https://pubmed.ncbi.nlm.nih.gov/34651656 -
3
المؤلفون: Sammy R. Shaver, William J. Hoekstra, Christopher M. Yates, Robert J. Schotzinger, Edward P. Garvey
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:3243-3248
مصطلحات موضوعية: Azoles, 0301 basic medicine, Posaconazole, Antifungal Agents, Pyridines, 030106 microbiology, Clinical Biochemistry, Tetrazoles, Pharmaceutical Science, medicine.disease_cause, Biochemistry, Microbiology, Aspergillus fumigatus, 03 medical and health sciences, Drug Discovery, medicine, Aspergillosis, Humans, Homology modeling, Molecular Biology, chemistry.chemical_classification, CYP3A4, biology, Chemistry, Organic Chemistry, Fungi, biology.organism_classification, Yeast, Molecular Docking Simulation, 030104 developmental biology, Mycoses, 14-alpha Demethylase Inhibitors, Drug Design, Cytochrome P450 Family 51, Dermatophyte, Molecular Medicine, Azole, Fluconazole, medicine.drug
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المؤلفون: Andrew T. Nishimoto, Edward P. Garvey, Sarah G. Whaley, Robert J. Schotzinger, Christopher M. Yates, P. David Rogers, William J. Hoekstra, Nathan P. Wiederhold, Qing Zhang
المصدر: Antimicrobial agents and chemotherapy. 63(10)
مصطلحات موضوعية: Antifungal Agents, Pyridines, Triazole, Tetrazoles, Candida glabrata, Microbial Sensitivity Tests, Microbiology, Fungal Proteins, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Drug Resistance, Fungal, Mechanisms of Resistance, Pharmacology (medical), 030212 general & internal medicine, Gene, Pharmacology, 0303 health sciences, biology, 030306 microbiology, Transporter, biology.organism_classification, Phenotype, In vitro, Infectious Diseases, chemistry, Efflux, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5045cc9547070ceb215a66698c6667
https://pubmed.ncbi.nlm.nih.gov/31383660 -
5
المؤلفون: P. David Rogers, Stephanie A. Flowers, Joachim Morschhäuser, Steven L. Kelly, Edward P. Garvey, Christopher M. Yates, William J. Hoekstra, Robert J. Schotzinger, Qing Zhang, Nathan P. Wiederhold, Andrew T. Nishimoto
المصدر: Antimicrobial Agents and Chemotherapy. 63
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Voriconazole, 0303 health sciences, Posaconazole, biology, 030306 microbiology, Itraconazole, Triazole, biology.organism_classification, Corpus albicans, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Infectious Diseases, chemistry, medicine, Azole, Experimental Therapeutics, Pharmacology (medical), Candida albicans, Fluconazole, 030304 developmental biology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3fa3156821ece9476b6baf2bc1cd04
https://doi.org/10.1128/aac.00341-19 -
6
المؤلفون: William J. Hoekstra, Sparks Steven, Edward P. Garvey, Robert J. Schotzinger, J. David Becherer
المصدر: Journal of the Endocrine Society
مصطلحات موضوعية: Aldosterone synthase, medicine.medical_specialty, chemistry.chemical_compound, Endocrinology, Aldosterone, biology, chemistry, Endocrinology, Diabetes and Metabolism, Internal medicine, biology.protein, medicine, Steroid Hormone Biology in Physiology and Disease, Steroid Hormones and Receptors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866f989e7299f881ee03d1fb43f25177
https://doi.org/10.1210/js.2019-or09-6 -
7
المؤلفون: Robert J. Schotzinger, Edward P. Garvey, Laura K. Najvar, Marcos Olivo, Elizabeth L. Berkow, Shawn R. Lockhart, Gabriel Catano, Rosie Jaramillo, Nathan P. Wiederhold, Christopher M. Yates, Thomas F. Patterson
المصدر: Antimicrobial Agents and Chemotherapy. 63
مصطلحات موضوعية: Pharmacology, 0303 health sciences, Kidney, 030306 microbiology, business.industry, Broth microdilution, In vitro, Multiple drug resistance, 03 medical and health sciences, chemistry.chemical_compound, Infectious Diseases, medicine.anatomical_structure, Candida auris, chemistry, In vivo, medicine, Pharmacology (medical), Caspofungin, business, Fluconazole, 030304 developmental biology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::557f440e0e5d3ddbd3452aa9c6747159
https://doi.org/10.1128/aac.02233-18 -
8
المؤلفون: Victoria J. Jackson, Martin John Slater, Edward P. Garvey, Binto Simon, David J. Berrisford, John M. Gardiner, Claire Walmsley
المصدر: Simon, B, Walmsley, C, Jackson, V J, Garvey, E P, Slater, M J, Berrisford, D J & Gardiner, J M 2018, ' Evaluation of neomycin analogues for HIV-1 RRE RNA recognition identifies enhanced activity simplified neamine analogues ', Bioorganic & medicinal chemistry letters . https://doi.org/10.1016/j.bmcl.2018.11.004
مصطلحات موضوعية: Stereochemistry, Anti-HIV Agents, Clinical Biochemistry, Human immunodeficiency virus (HIV), Pharmaceutical Science, medicine.disease_cause, Response Elements, 01 natural sciences, Biochemistry, Reductive amination, Structure-Activity Relationship, Drug Discovery, medicine, Molecular Biology, Neamine, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, RNA, Neomycin, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HIV-1, Molecular Medicine, RNA, Viral, medicine.drug, Framycetin
وصف الملف: application/pdf
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المؤلفون: Thomas F. Patterson, Edward P. Garvey, Nathan P. Wiederhold, William J. Hoekstra, Amy Wang, Elizabeth A. Ottinger, Robert J. Schotzinger, Xin Xu, Jim Cradock, Marcos Olivo, Rosie Jaramillo, Laura K. Najvar, Mark Behnke, William R. Kirkpatrick, Stephen Brand, Asaf Alimardanov
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Cryptococcus neoformans, biology, business.industry, Maintenance dose, 030106 microbiology, biology.organism_classification, Placebo, Loading dose, 03 medical and health sciences, Regimen, 0302 clinical medicine, Infectious Diseases, Pharmacokinetics, In vivo, Medicine, Pharmacology (medical), Experimental Therapeutics, 030212 general & internal medicine, business, Cryptococcal meningitis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d9ee21373afd31307cacd678ea123b
https://europepmc.org/articles/PMC6201077/ -
10
المؤلفون: Nathan P, Wiederhold, Shawn R, Lockhart, Laura K, Najvar, Elizabeth L, Berkow, Rosie, Jaramillo, Marcos, Olivo, Edward P, Garvey, Christopher M, Yates, Robert J, Schotzinger, Gabriel, Catano, Thomas F, Patterson
المصدر: Antimicrobial agents and chemotherapy. 63(3)
مصطلحات موضوعية: Antifungal Agents, Pyridines, Tetrazoles, Microbial Sensitivity Tests, Disease Models, Animal, Mice, Sterol 14-Demethylase, 14-alpha Demethylase Inhibitors, Caspofungin, Animals, Humans, Candidiasis, Invasive, Experimental Therapeutics, Fluconazole, Candida
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::22bd341a2ae1a63241095480729ff5dd
https://pubmed.ncbi.nlm.nih.gov/30530603