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المؤلفون: Yuan-Kun Lee, Yi Shuen Hong, Eleanor Jing Yi Cheong, Edward R. Browne, Eric Chun Yong Chan, Han Chen Ku, Niranjan Nagarajan, Amanda Hui Qi Ng, Lian Yee Yip, Sze Han Lee, Chiu Cheong Aw, Jessalyn Mei Xuan Chan, Ratha Mahendran, Kern Rei Chng, Winston Hecheng Xu
المصدر: Hepatology (Baltimore, Md.). 67(1)
مصطلحات موضوعية: 0301 basic medicine, Male, Biology, Pharmacology, Gut flora, Severity of Illness Index, 03 medical and health sciences, Deglucuronidation, Random Allocation, 0302 clinical medicine, Liver Function Tests, Reference Values, Lactobacillus, medicine, Animals, Hepatology, medicine.diagnostic_test, Dose-Response Relationship, Drug, Biopsy, Needle, Rats, Inbred Strains, biology.organism_classification, Immunohistochemistry, Gastrointestinal Microbiome, Rats, Disease Models, Animal, 030104 developmental biology, Metagenomics, 030220 oncology & carcinogenesis, Tacrine, Transaminitis, Bacteroides, Chemical and Drug Induced Liver Injury, Liver function tests, medicine.drug
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المصدر: Drug Metabolism and Disposition. 39:402-411
مصطلحات موضوعية: Male, Aging, Metabolic Clearance Rate, Biological Availability, Pharmaceutical Science, Hypothermia, Pharmacology, Random Allocation, chemistry.chemical_compound, Piperidines, Pharmacokinetics, Tremor, medicine, Galantamine, Animals, Cholinesterases, Donepezil, Cholinesterase, Receptor, Muscarinic M2, Dose-Response Relationship, Drug, biology, Chemistry, Brain, Rats, Inbred Strains, Acetylcholinesterase, Rats, Tears, Tacrine, Pharmacodynamics, Indans, biology.protein, Cholinesterase Inhibitors, Salivation, Half-Life, medicine.drug, Blood sampling
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57892ed51050f3310f424426cb373031
https://doi.org/10.1124/dmd.110.035964 -
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المؤلفون: Catherine W. Goh, Edward R. Browne, Aveline H. Neo, Lee Sun New, Hui Ting Chng, Eric Chun Yong Chan
المصدر: Journal of Pharmaceutical and Biomedical Analysis. 51:754-757
مصطلحات موضوعية: Brain Chemistry, Detection limit, Bioanalysis, Chromatography, Thioctic Acid, Clinical Biochemistry, Extraction (chemistry), Analytical chemistry, Administration, Oral, Pharmaceutical Science, High-performance liquid chromatography, Rats, Analytical Chemistry, Lipoic acid, chemistry.chemical_compound, Acetic acid, chemistry, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Drug Discovery, Animals, Protein precipitation, Tissue Distribution, Spectroscopy, Chromatography, Liquid
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المؤلفون: Zeenat Atcha, Edward R. Browne, Lee Sun New, Chiu Cheong Aw, Catherine Wenhui Goh, Woei Shin Chen, Eric Chun Yong Chan, Dilys P Q Goh, Aveline H. Neo
المصدر: Journal of Proteome Research. 8:5679-5690
مصطلحات موضوعية: Male, Pharmacology, Biochemistry, Correlation, chemistry.chemical_compound, Cognition, Text mining, Piperidines, Tandem Mass Spectrometry, Galantamine, Metabolome, Animals, Medicine, Donepezil, Neurotransmitter, Brain Chemistry, Behavior, Animal, Receiver operating characteristic, business.industry, Rats, Inbred Strains, General Chemistry, Rats, chemistry, Indans, business, medicine.drug
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المؤلفون: Edward R. Browne, Catherine W. Goh, Lee Sun New, Lee Cheng Phua, Eric Chun Yong Chan, Aveline H. Neo
المصدر: Pharmaceutical Research. 25:2639-2649
مصطلحات موضوعية: Male, Metabolic Clearance Rate, Pharmaceutical Science, Mitochondria, Liver, Citrate (si)-Synthase, Pharmacology, Mitochondrion, Mass Spectrometry, chemistry.chemical_compound, Pharmacokinetics, In vivo, medicine, Animals, Drug Interactions, Pharmacology (medical), Valproic Acid, Thioctic Acid, biology, Chemistry, Organic Chemistry, Drug interaction, In vitro, Rats, Lipoic acid, Enzyme inhibitor, biology.protein, Molecular Medicine, Oxidation-Reduction, Chromatography, Liquid, Protein Binding, Biotechnology, medicine.drug
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المؤلفون: Sumitra Ramachandran, Angela A. Dunne, Neil Derek Miller, Laiq Chaudry, Vincent Jaquet, Craig Allan, Aleksandra Filippova, Jean Lim, Ceri H. Davies, Agnes B. Ong, May Thu Ma, Shabina Nasir, Woei Shin Chen, Nicole Y. Ye, Edward R. Browne, Kiew Ching K Lee, Shihua Liao, Douglas G. Johns, Angela Bridges, Yasuji Matsuoka, Chiu Cheong Aw, A. Richard Rutter, Adeline L.W. Chueng, Dizheng Li, Deborah W. Chen, Sri Mulyanidewi, Sarah Duncan, Tamara Seredenina, Gary Pettman, Kazufumi Hirano, Pamela P. Oon
المصدر: Antioxidants & redox signaling, Vol. 23, No 5 (2015) pp. 358-374
مصطلحات موضوعية: Male, Physiology, Clinical Biochemistry, Aminopyridines, ddc:616.07, medicine.disease_cause, Biochemistry, Rats, Sprague-Dawley, Enzyme Inhibitors / therapeutic use, Membrane Glycoproteins / metabolism, Drug Discovery, Enzyme Inhibitors, Pancreatitis / drug therapy, Cells, Cultured, General Environmental Science, chemistry.chemical_classification, Sulfonamides, Membrane Glycoproteins, NADPH oxidase, biology, Chemistry, Enzyme Inhibitors / pharmacology, respiratory system, Small molecule, 3. Good health, Aminopyridines / chemistry, NADPH Oxidase 2, cardiovascular system, Sulfonamides / chemistry, circulatory and respiratory physiology, inorganic chemicals, In vivo, Forum Original Research Communication, medicine, Animals, NADPH Oxidases / metabolism, Molecular Biology, NOx, Sulfonamides / pharmacology, Reactive oxygen species, Aminopyridines / pharmacology, NADPH Oxidases / antagonists & inhibitors, Reactive Oxygen Species / metabolism, NADPH Oxidases, Cell Biology, In vitro, Mice, Inbred C57BL, Enzyme, Pancreatitis, Membrane Glycoproteins / antagonists & inhibitors, biology.protein, General Earth and Planetary Sciences, Reactive Oxygen Species, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7ea3e136424a97ddab898f120e2665
https://europepmc.org/articles/PMC4545375/ -
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المؤلفون: Tao Liu, Zeping Hu, Thomas E. Angel, Eric Chun Yong Chan, Paul C. Ho, Edward R. Browne
المصدر: Journal of proteome research. 11(12)
مصطلحات موضوعية: Zymosterol, Male, medicine.medical_specialty, Hydrocortisone, Transgene, Linoleic acid, Mice, Transgenic, Carbohydrate metabolism, Steroid biosynthesis, Biology, Biochemistry, Gluconates, Gas Chromatography-Mass Spectrometry, Palmitic acid, Immunoenzyme Techniques, Linoleic Acid, chemistry.chemical_compound, Mice, Alzheimer Disease, Internal medicine, medicine, Metabolome, Animals, Metabolomics, Amino Acids, Progesterone, Brain, General Chemistry, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, Glucose, chemistry, Carbohydrate Metabolism, Arachidonic acid, Energy Metabolism, Biomarkers
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المؤلفون: Yunhong Huang, Yu Ding, Ting Li, Edward R. Browne, Yun Jin, Yingxia Sang, Adrian Hall, Andrew John Eatherton, Na Rong, Ishrut Hussain, William L. Mitchell, Yi Li, Yiwen Wu, Lit-Fui Lau, Xiu-Juan Yang, David C. Harrison, Zehong Wan, Ziqiang Cheng, Yasuji Matsuoka, Jinqiang Zhang, Shiyi Jin, Liang Ye
المصدر: Neuropharmacology. 70
مصطلحات موضوعية: Male, Pyridines, Primary Cell Culture, Notch signaling pathway, Administration, Oral, Biological Availability, Pharmacology, Cleavage (embryo), Pathogenesis, Cellular and Molecular Neuroscience, In vivo, Oral administration, Amyloid precursor protein, Animals, Receptor, Neurons, Amyloid beta-Peptides, Thymocytes, biology, Dose-Response Relationship, Drug, Receptors, Notch, Chemistry, P3 peptide, Brain, Rats, Pyridazines, Biochemistry, biology.protein, Amyloid Precursor Protein Secretases
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المؤلفون: Kazufumi Hirano, Kirsten L. Searle, Shabina Nasir, A. Richard Rutter, Edward R. Browne, Chiu-Cheong Aw
المصدر: Neuroscience letters. 503(3)
مصطلحات موضوعية: Olanzapine, Male, Chlorpromazine, medicine.medical_treatment, Pharmacology, Piperazines, Rats, Sprague-Dawley, Benzodiazepines, Radioligand Assay, medicine, Animals, Receptor, Antipsychotic, Clozapine, 5-HT receptor, Sulfonamides, Dose-Response Relationship, Drug, General Neuroscience, Brain, medicine.disease, Rats, Schizophrenia, Receptors, Serotonin, 5-HT6 receptor, Psychology, medicine.drug, Antipsychotic Agents
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المؤلفون: Eric Chun Yong Chan, Kai Lun Chang, Edward R. Browne, Chiu Cheong Aw, Catherine W. Goh, Lee Sun New, Mainak Mal
المصدر: Journal of proteome research. 10(4)
مصطلحات موضوعية: medicine.disease_cause, Mass spectrometry, Biochemistry, Gas Chromatography-Mass Spectrometry, Rats, Sprague-Dawley, Huntington's disease, Galantamine, medicine, Animals, Metabolomics, Nootropic Agents, chemistry.chemical_classification, Electron Transport Complex II, Neurodegeneration, Brain, General Chemistry, medicine.disease, Nitro Compounds, Phenotype, Mitochondria, Rats, Disease Models, Animal, Oxidative Stress, Enzyme, Huntington Disease, chemistry, Metabolome, Time-of-flight mass spectrometry, Propionates, Oxidative stress, medicine.drug
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