المؤلفون: Marinina KS; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, 29 Polytechnicheskaya str., St. Petersburg 195251, Russia., Bezprozvanny IB; Department of Physiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9040, United States., Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, 29 Polytechnicheskaya str., St. Petersburg 195251, Russia.

المصدر: Human molecular genetics [Hum Mol Genet] 2024 Aug 06; Vol. 33 (16), pp. 1406-1419.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Anxiety*/drug therapy , Anxiety*/physiopathology , Depression*/drug therapy , Depression*/genetics , Depression*/physiopathology , Folic Acid*/pharmacology , Folic Acid*/administration & dosage , Mice, Transgenic* , Disease Models, Animal* , Machado-Joseph Disease*/drug therapy , Machado-Joseph Disease*/genetics , Machado-Joseph Disease*/physiopathology , Machado-Joseph Disease*/pathology , Chlorzoxazone*/pharmacology, Animals ; Mice ; Purkinje Cells/drug effects ; Purkinje Cells/metabolism ; Purkinje Cells/pathology ; Memory/drug effects ; Humans ; Cerebellum/drug effects ; Cerebellum/metabolism ; Male ; Ataxin-3/genetics ; Ataxin-3/metabolism

المؤلفون: Marinina KS; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, Saint Petersburg, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, Saint Petersburg, Russia. Ilya.Bezprozvanny@UTSouthwestern.edu.; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Ilya.Bezprozvanny@UTSouthwestern.edu., Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, Saint Petersburg, Russia. biopolya@gmail.com.

المصدر: Cerebellum (London, England) [Cerebellum] 2024 Feb; Vol. 23 (1), pp. 145-161. Date of Electronic Publication: 2023 Jan 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101089443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4230 (Electronic) Linking ISSN: 14734222 NLM ISO Abbreviation: Cerebellum Subsets: MEDLINE

مواضيع طبية MeSH: Spinocerebellar Ataxias*/genetics , Spinocerebellar Ataxias*/psychology , Cognitive Dysfunction*/genetics, Humans ; Mice ; Animals ; Cerebellum ; Purkinje Cells ; Mice, Transgenic ; Disease Models, Animal

المؤلفون: Marinina KS; Laboratory of Molecular Neurodegeneration, Insitute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 29 Polytechnicheskaya str., St. Petersburg 195251, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Insitute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 29 Polytechnicheskaya str., St. Petersburg 195251, Russia.; Department of Physiology, ND 12.200AA, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9040, United States., Egorova PA; Laboratory of Molecular Neurodegeneration, Insitute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 29 Polytechnicheskaya str., St. Petersburg 195251, Russia.

المصدر: Human molecular genetics [Hum Mol Genet] 2024 Feb 01; Vol. 33 (4), pp. 299-317.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Machado-Joseph Disease*/genetics , Machado-Joseph Disease*/metabolism, Humans ; Mice ; Animals ; Depression/genetics ; Cerebellum/metabolism ; Ataxin-3/genetics ; Ataxin-3/metabolism ; Mice, Transgenic ; Anxiety/genetics

المؤلفون: Marinina KS; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. Ilya.Bezprozvanny@UTSouthwestern.edu.; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Ilya.Bezprozvanny@UTSouthwestern.edu., Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. biopolya@gmail.com.

المصدر: Scientific reports [Sci Rep] 2023 Aug 03; Vol. 13 (1), pp. 12588. Date of Electronic Publication: 2023 Aug 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Spinocerebellar Ataxias*/drug therapy , Spinocerebellar Ataxias*/genetics , Spinocerebellar Ataxias*/pathology , Cognitive Dysfunction*/drug therapy, Mice ; Animals ; Chlorzoxazone ; Mice, Transgenic ; Cognition

المؤلفون: Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Marinina KS; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: Ilya.Bezprozvanny@UTSouthwestern.edu.

المصدر: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2023 Jun; Vol. 1870 (5), pp. 119466. Date of Electronic Publication: 2023 Mar 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE

مواضيع طبية MeSH: Purkinje Cells*/metabolism , Spinocerebellar Ataxias*/genetics, Mice ; Animals ; Calcium Signaling/physiology ; Calcium/metabolism ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism

المؤلفون: Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. bio_polya@mail.ru., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. Ilya.Bezprozvanny@UTSouthwestern.edu.; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Ilya.Bezprozvanny@UTSouthwestern.edu.

المصدر: Cerebellum (London, England) [Cerebellum] 2022 Oct; Vol. 21 (5), pp. 742-749. Date of Electronic Publication: 2022 Jan 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101089443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4230 (Electronic) Linking ISSN: 14734222 NLM ISO Abbreviation: Cerebellum Subsets: MEDLINE

مواضيع طبية MeSH: Ataxin-2*/metabolism , Spinocerebellar Ataxias*/drug therapy , Spinocerebellar Ataxias*/genetics , Spinocerebellar Ataxias*/metabolism, Animals ; Cerebellum ; Mice ; Mice, Transgenic ; Purkinje Cells/physiology

المؤلفون: El-Sayed NS; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States., Nam YW; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States., Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, Politekhnicheskaya Ulitsa, 29, St. Petersburg 195251, Russia., Nguyen HM; Department of Pharmacology, School of Medicine, University of California, Davis, 451 Health Sciences Drive, Davis, California 95616, United States., Orfali R; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States., Rahman MA; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States., Yang G; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States., Wulff H; Department of Pharmacology, School of Medicine, University of California, Davis, 451 Health Sciences Drive, Davis, California 95616, United States., Bezprozvanny I; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, Politekhnicheskaya Ulitsa, 29, St. Petersburg 195251, Russia.; Department of Physiology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, Texas 75390, United States., Parang K; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States., Zhang M; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, 9401 Jeronimo Road, Irvine, California 92618, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Jan 13; Vol. 65 (1), pp. 303-322. Date of Electronic Publication: 2021 Dec 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cerebellum*/drug effects , Membrane Transport Modulators*/chemistry , Membrane Transport Modulators*/pharmacology , Potassium Channels, Calcium-Activated*/agonists , Potassium Channels, Calcium-Activated*/metabolism , Purkinje Cells*/drug effects , Pyrimidines*/chemistry , Spinocerebellar Ataxias*/drug therapy , Spinocerebellar Ataxias*/metabolism , Spinocerebellar Ataxias*/pathology, Animals ; Female ; Male ; Mice ; Disease Models, Animal ; Ion Channel Gating ; Structure-Activity Relationship

المؤلفون: Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. Electronic address: bio_polya@mail.ru., Gavrilova AV; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: Ilya.Bezprozvanny@UTSouthwestern.edu.

المصدر: Cell calcium [Cell Calcium] 2021 Jan; Vol. 93, pp. 102319. Date of Electronic Publication: 2020 Nov 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8006226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1991 (Electronic) Linking ISSN: 01434160 NLM ISO Abbreviation: Cell Calcium Subsets: MEDLINE

مواضيع طبية MeSH: Action Potentials/*physiology , Cerebellum/*physiopathology , Purkinje Cells/*physiology , Spinocerebellar Ataxias/*physiopathology , Wakefulness/*physiology, Action Potentials/drug effects ; Aging/pathology ; Animals ; Chlorzoxazone/administration & dosage ; Chlorzoxazone/pharmacology ; Disease Models, Animal ; Injections, Intraperitoneal ; Mice, Transgenic ; Motor Activity/drug effects ; Purkinje Cells/drug effects

المؤلفون: Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Gavrilova AV; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, United States.

المصدر: Frontiers in neuroscience [Front Neurosci] 2020 Apr 03; Vol. 14, pp. 279. Date of Electronic Publication: 2020 Apr 03 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101478481 Publication Model: eCollection Cited Medium: Print ISSN: 1662-4548 (Print) Linking ISSN: 1662453X NLM ISO Abbreviation: Front Neurosci Subsets: PubMed not MEDLINE

المؤلفون: Egorova PA; Laboratory of Molecular Neurodegeneration, Peter the Great St.Petersburg Polytechnic University, St. Petersburg, 195251, Russia., Bezprozvanny IB; Laboratory of Molecular Neurodegeneration, Peter the Great St.Petersburg Polytechnic University, St. Petersburg, 195251, Russia. Ilya.Bezprozvanny@UTSouthwestern.edu.; Department of Physiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, ND12.200, Dallas, Texas, 75390, USA. Ilya.Bezprozvanny@UTSouthwestern.edu.

المصدر: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2019 Oct; Vol. 16 (4), pp. 1050-1073.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Experimental NeuroTherapeutics Country of Publication: United States NLM ID: 101290381 Publication Model: Print Cited Medium: Internet ISSN: 1878-7479 (Electronic) Linking ISSN: 18787479 NLM ISO Abbreviation: Neurotherapeutics Subsets: MEDLINE

مواضيع طبية MeSH: Ataxin-2/*genetics , Peptides/*genetics , Spinocerebellar Ataxias/*genetics , Spinocerebellar Ataxias/*therapy, Animals ; Ataxin-2/metabolism ; Brain/metabolism ; Brain/pathology ; Genetic Therapy/methods ; Genetic Therapy/trends ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/transplantation ; Mutation/physiology ; Nerve Net/metabolism ; Nerve Net/pathology ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Oligonucleotides, Antisense/administration & dosage ; Oligonucleotides, Antisense/genetics ; Oligonucleotides, Antisense/metabolism ; Oxidative Stress/physiology ; Peptides/metabolism ; Spinocerebellar Ataxias/metabolism ; Stem Cell Transplantation