المؤلفون: Ramos A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Koch CE; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Liu-Lupo Y; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Hellinger RD; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Kyung T; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Abbott KL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Fröse J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Goulet D; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Gordon KS; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Eidell KP; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Leclerc P; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Whittaker CA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Larson RC; Cellular Immunotherapy Program, Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Immunology Program, Harvard Medical School, Boston, MA, USA., Muscato AJ; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA., Yates KB; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA., Dubrot J; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA.; Solid Tumors Program, Division of Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain., Doench JG; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA., Regev A; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Vander Heiden MG; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA., Maus MV; Cellular Immunotherapy Program, Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Immunology Program, Harvard Medical School, Boston, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA.; Ragon Institute of MIT, MGH, and Harvard, Cambridge, MA, USA., Manguso RT; Immunology Program, Harvard Medical School, Boston, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, 02142, USA., Birnbaum ME; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Hemann MT; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. hemann@mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. hemann@mit.edu.

المصدر: Nature communications [Nat Commun] 2023 Dec 05; Vol. 14 (1), pp. 8048. Date of Electronic Publication: 2023 Dec 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Chimeric Antigen* , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/therapy , Leukemia* , Burkitt Lymphoma*, Humans ; Animals ; Mice ; RNA, Guide, CRISPR-Cas Systems ; Immunotherapy, Adoptive ; T-Lymphocytes ; Tumor Microenvironment

المؤلفون: Eidell KP; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Lovy A; Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA., Sylvain NR; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Scangarello FA; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Muendlein HI; Graduate Program in Genetics, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Ophir MJ; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Nguyen K; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Seminario MC; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Bunnell SC; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA.

المصدر: Journal of cell science [J Cell Sci] 2021 Aug 15; Vol. 134 (16). Date of Electronic Publication: 2021 Aug 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

مواضيع طبية MeSH: Dyneins*/genetics , Lymphocyte Function-Associated Antigen-1*/metabolism, Cell Adhesion ; Humans ; Membrane Proteins/metabolism ; Myosins ; Receptors, Antigen, T-Cell/metabolism

المؤلفون: Muendlein HI; Graduate Program in Genetics, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Jetton D; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Connolly WM; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Eidell KP; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Magri Z; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Smirnova I; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Poltorak A; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA. alexander.poltorak@tufts.edu.; Laboratory of Genetics of Innate Immunity, Petrozavodsk State University, Petrozavodsk, Republic of Karelia 185910, Russia.

المصدر: Science (New York, N.Y.) [Science] 2020 Mar 20; Vol. 367 (6484), pp. 1379-1384.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Macrophage Activation* , Pyroptosis*, CASP8 and FADD-Like Apoptosis Regulating Protein/*physiology , Electron Transport Complex II/*metabolism , Inflammasomes/*metabolism , Macrophages/*physiology, Animals ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; Caspase 1/metabolism ; Caspase 8/metabolism ; Gene Knockdown Techniques ; Interleukin-1beta/metabolism ; Lipopolysaccharides/immunology ; Macrophages/immunology ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism

المؤلفون: Lewis JB; Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA., Scangarello FA; Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA.; Medical Scientist Training Program, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA., Murphy JM; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Eidell KP; Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA., Sodipo MO; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Ophir MJ; Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA., Sargeant R; Pacific Immunology Corporation, Ramona, CA 92065, USA., Seminario MC; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Bunnell SC; Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA stephen.bunnell@tufts.edu.; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA.

المصدر: Journal of cell science [J Cell Sci] 2018 Nov 08; Vol. 131 (21). Date of Electronic Publication: 2018 Nov 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Jurkat Cells/*metabolism , Phosphoproteins/*metabolism , Receptors, Antigen, T-Cell/*metabolism, Adaptor Proteins, Signal Transducing/immunology ; Cell Adhesion/physiology ; Cell Communication/physiology ; Cytoskeleton/immunology ; Cytoskeleton/metabolism ; Humans ; Jurkat Cells/cytology ; Jurkat Cells/immunology ; Lymphocyte Activation ; Phosphoproteins/immunology ; Phosphorylation ; Receptors, Antigen, T-Cell/immunology ; Signal Transduction ; src Homology Domains

المؤلفون: Farrell A; Department of Biology, Boston College, Chestnut Hill, MA 02467, USA., Thirugnanam S, Lorestani A, Dvorin JD, Eidell KP, Ferguson DJ, Anderson-White BR, Duraisingh MT, Marth GT, Gubbels MJ

المصدر: Science (New York, N.Y.) [Science] 2012 Jan 13; Vol. 335 (6065), pp. 218-21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Exocytosis*, Calcium/*metabolism , Calcium-Binding Proteins/*metabolism , Organelles/*metabolism , Protozoan Proteins/*metabolism , Toxoplasma/*physiology, Amino Acid Sequence ; Calcium-Binding Proteins/chemistry ; Calcium-Binding Proteins/genetics ; Cell Line ; Genes, Protozoan ; Genetic Complementation Test ; Genome, Protozoan ; Humans ; Models, Molecular ; Molecular Sequence Data ; Movement ; Mutagenesis ; Plasmodium falciparum/genetics ; Plasmodium falciparum/growth & development ; Plasmodium falciparum/physiology ; Point Mutation ; Protein Structure, Tertiary ; Protozoan Proteins/chemistry ; Protozoan Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Toxoplasma/genetics ; Toxoplasma/growth & development ; Toxoplasma/ultrastructure

المؤلفون: Eidell KP; Department of Biology, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA., Burke T, Gubbels MJ

المصدر: Molecular and biochemical parasitology [Mol Biochem Parasitol] 2010 Jun; Vol. 171 (2), pp. 97-103. Date of Electronic Publication: 2010 Mar 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8006324 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9428 (Electronic) Linking ISSN: 01666851 NLM ISO Abbreviation: Mol Biochem Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Mutagenesis*, Fibroblasts/*parasitology , Genetics, Microbial/*methods , Parasitology/*methods , Toxoplasma/*isolation & purification , Toxoplasma/*physiology, Cells, Cultured ; Humans ; Toxoplasma/genetics