المؤلفون: Seif el-Din, Sayed H, Salem, MB, El-Lakkany, NM, Hammam, OA, Nasr, SM, Okasha, H, Ahmed, LA, Saleh, S, Botros, SS

المصدر: Human & Experimental Toxicology; Sep2021, Vol. 40 Issue 9, p1496-1509, 14p

مصطلحات موضوعية: NON-alcoholic fatty liver disease, DYSBIOSIS, GUT microbiome, FATTY liver, RATS, PROBIOTICS, HIGH-fat diet

المؤلفون: El-Maadawy, WH, Hammam, OA, Seif el-Din, SH, El-Lakkany, NM

المصدر: Human & Experimental Toxicology; Apr2020, Vol. 39 Issue 4, p440-450, 11p, 1 Chart, 3 Graphs

مصطلحات موضوعية: ALPHA-linolenic acid, PLATELET-derived growth factor, AUTOPHAGY, MYOFIBROBLASTS, LIVER cells, LIPOIC acid, HEPATIC fibrosis, LIVER

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المؤلفون: Salem MB; Department of Pharmacology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza, 12411, Egypt., El-Lakkany NM; Department of Pharmacology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza, 12411, Egypt., Seif El-Din SH; Department of Pharmacology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza, 12411, Egypt., Hammam OA; Department of Pathology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza, 12411, Egypt., Samir S; Department of Biochemistry and Molecular Biology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza, 12411, Egypt.

المصدر: Heliyon [Heliyon] 2024 Mar 07; Vol. 10 (6), pp. e27527. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE

المؤلفون: Salem MB; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: m.salem@tbri.gov.eg., Saleh AM; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of pharmacy (Boys), Al-Azhar University, Cairo, Egypt., Seif El-Din SH; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt., Samir S; Biochemistry and Molecular Biology Department, Theodor Bilharz Research Institute, Giza, Egypt., Hammam OA; Pathology Department, Theodor Bilharz Research Institute, Giza, Egypt., El-Lakkany NM; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt.

المصدر: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2024 Mar; Vol. 484, pp. 116880. Date of Electronic Publication: 2024 Mar 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Indomethacin*/toxicity , Stomach Ulcer*/chemically induced , Stomach Ulcer*/drug therapy , Stomach Ulcer*/pathology, Humans ; Mice ; Animals ; Quercetin/pharmacology ; Quercetin/therapeutic use ; Molecular Docking Simulation ; Ulcer/metabolism ; Ulcer/pathology ; NF-kappa B/metabolism ; Myeloid Differentiation Factor 88/metabolism ; Toll-Like Receptor 4/metabolism ; Gastric Mucosa/metabolism ; Gastric Mucosa/pathology

المؤلفون: Hendawy AS; Department of Pharmacology, Theodor Bilharz Research Institute, Kornaish El Nile, Warrak El-Hadar, Imbaba, 30, Giza 12411, Egypt., El-Lakkany NM; Department of Pharmacology, Theodor Bilharz Research Institute, Kornaish El Nile, Warrak El-Hadar, Imbaba, 30, Giza 12411, Egypt., Mantawy EM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity Street, Abbasia, Cairo 11566, Egypt., Hammam OA; Department of Pathology, Theodor Bilharz Research Institute, Kornaish El Nile, Warrak El-Hadar, Imbaba, 30, Giza 12411, Egypt., Botros SS; Department of Pharmacology, Theodor Bilharz Research Institute, Kornaish El Nile, Warrak El-Hadar, Imbaba, 30, Giza 12411, Egypt., El-Demerdash E; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity Street, Abbasia, Cairo 11566, Egypt. Electronic address: ebtehal_dm@pharma.asu.edu.eg.

المصدر: Life sciences [Life Sci] 2022 Sep 01; Vol. 304, pp. 120695. Date of Electronic Publication: 2022 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/metabolism , Insulin Resistance* , Non-alcoholic Fatty Liver Disease*/drug therapy , Non-alcoholic Fatty Liver Disease*/metabolism , Oxidative Stress*/drug effects , Vildagliptin*/pharmacology, Animals ; Diet, High-Fat/adverse effects ; Insulin/metabolism ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Male ; Phosphatidylinositol 3-Kinases/metabolism ; Rats ; Rats, Sprague-Dawley

المؤلفون: Sabra AA; Professor of Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: abdelnassersabraa@yahoo.com., Salem MB; Lecturer of Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: m.salem@tbri.gov.eg., William S; Professor of Parasitology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: samiaw2006@yahoo.com., Hammam OA; Professor of Pathology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: totoali1@hotmail.com., El-Lakkany NM; Professor of Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: n.ellakkany@tbri.gov.eg.

المصدر: Experimental parasitology [Exp Parasitol] 2022 Aug; Vol. 239, pp. 108293. Date of Electronic Publication: 2022 Jun 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0370713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2449 (Electronic) Linking ISSN: 00144894 NLM ISO Abbreviation: Exp Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Anthelmintics*/pharmacology , Anthelmintics*/therapeutic use , Schistosomiasis mansoni*/drug therapy , Schistosomiasis mansoni*/pathology, Animals ; Itraconazole/pharmacology ; Itraconazole/therapeutic use ; Liver/pathology ; Mice ; Praziquantel/pharmacology ; Praziquantel/therapeutic use ; Schistosoma mansoni

المؤلفون: El-Lakkany NM; Department of Pharmacology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza 12411, Egypt. Electronic address: n.ellakkany@tbri.gov.eg., Elkattan HH; Department of Pharmacology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, Giza 12411, Egypt., Elsisi AE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.

المصدر: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Dec 01; Vol. 432, pp. 115767. Date of Electronic Publication: 2021 Oct 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Neovascularization, Pathologic*, Angiogenesis Inhibitors/*pharmacology , Antineoplastic Combined Chemotherapy Protocols/*pharmacology , Apoptosis/*drug effects , Carcinoma, Ehrlich Tumor/*drug therapy , Cell Proliferation/*drug effects , Gossypol/*pharmacology , Imidazoles/*pharmacology , Pyridazines/*pharmacology, Animals ; Apoptosis Regulatory Proteins/metabolism ; Carcinoma, Ehrlich Tumor/metabolism ; Carcinoma, Ehrlich Tumor/pathology ; Cell Line, Tumor ; Female ; Mice ; Oxidative Stress/drug effects ; Receptor, Fibroblast Growth Factor, Type 4/metabolism ; Signal Transduction ; Tumor Burden/drug effects ; Vascular Endothelial Growth Factor A/metabolism

المؤلفون: Sebastian-Perez V; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain., García-Rubia A; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain., Seif El-Din SH; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt., Sabra AA; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt., El-Lakkany NM; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt., William S; Parasitology Department, Theodor Bilharz Research Institute, Giza, Egypt., Blundell TL; Department of Biochemistry, University of Cambridge, Cambridge, UK., Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium., Martinez A; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain., Campillo NE; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain., Botros SS; Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt., Gil C; Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain.

المصدر: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 511-523.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aldehyde Reductase/*antagonists & inhibitors , Enzyme Inhibitors/*chemistry , Enzyme Inhibitors/*pharmacology , Quinazolines/*chemistry , Quinazolines/*pharmacology , Schistosoma mansoni/*drug effects, Aldehyde Reductase/metabolism ; Animals ; Anthelmintics ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Male ; Mice ; Models, Molecular ; Molecular Structure ; Quinazolines/chemical synthesis ; Schistosoma mansoni/enzymology ; Structure-Activity Relationship

المؤلفون: Ahmed LA; Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: lamiaa.ahmed@pharma.cu.edu.eg., Salem MB; Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: drmahabadr86@gmail.com., Seif El-Din SH; Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: s.seifeldin@tbri.gov.eg., El-Lakkany NM; Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: n.ellakkany@tbri.gov.eg., Ahmed HO; Biochemistry, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: hend.oaa@gmail.com., Nasr SM; Biochemistry, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: samitbri@gmail.com., Hammam OA; Pathology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: totoali1@hotmail.com., Botros SS; Pharmacology, Theodor Bilharz Research Institute, Giza, Egypt. Electronic address: sanaabotros113@gmail.com., Saleh S; Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: samira.saleh@pharma.cu.edu.eg.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2020 Nov 15; Vol. 887, pp. 173461. Date of Electronic Publication: 2020 Aug 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Toll-Like Receptor 4*/metabolism, Autophagy/*drug effects , Gastrointestinal Microbiome/*drug effects , Hypoglycemic Agents/*administration & dosage , Metformin/*administration & dosage , Non-alcoholic Fatty Liver Disease/*drug therapy , Non-alcoholic Fatty Liver Disease/*metabolism, Animals ; Autophagy/physiology ; Diet, High-Fat/adverse effects ; Drug Therapy, Combination ; Gastrointestinal Microbiome/physiology ; Lipopolysaccharides/toxicity ; Male ; Probiotics/administration & dosage ; Random Allocation ; Rats ; Rats, Sprague-Dawley