المؤلفون: Bhuvaneish T. Selvaraj, Matthew R. Livesey, Chen Zhao, Jenna M. Gregory, Owain T. James, Elaine M. Cleary, Amit K. Chouhan, Angus B. Gane, Emma M. Perkins, Owen Dando, Simon G. Lillico, Youn-Bok Lee, Agnes L. Nishimura, Urjana Poreci, Sai Thankamony, Meryll Pray, Navneet A. Vasistha, Dario Magnani, Shyamanga Borooah, Karen Burr, David Story, Alexander McCampbell, Christopher E. Shaw, Peter C. Kind, Timothy J. Aitman, C. Bruce A. Whitelaw, Ian Wilmut, Colin Smith, Gareth B. Miles, Giles E. Hardingham, David J. A. Wyllie, Siddharthan Chandran

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/6a962a5b03a74471945829a86138ad2f

المؤلفون: S Chandran, Owain T. James, David J. A. Wyllie, Emma M. Perkins, Matthew R. Livesey, Chen Zhao, C Rosanne M Ausems, Jenna M. Gregory, Alessandra Cardinali, Bhuvaneish T. Selvaraj, Karen Burr, Dario Magnani, Samantha K. Barton, Giles E. Hardingham, Owen G. James, Nicholas M. Morton, Roderick N. Carter, Elaine M. Cleary, David Story, Navneet A. Vasistha

المصدر: Barton, S K, Magnani, D, James, O G, Livesey, M R, Selvaraj, B T, James, O T, Perkins, E M, Gregory, J M, Cleary, E, Ausems, C R M, Carter, R, Vasistha, N A, Zhao, C, Burr, K, Story, D, Cardinali, A, Morton, N M, Hardingham, G E, Wyllie, D J A & Chandran, S 2021, ' TDP-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model ', Brain Communications, vol. 3, no. 4, fcab255 . https://doi.org/10.1093/braincomms/fcab255

مصطلحات موضوعية: Mutation, amyotrophic lateral sclerosis, induced pluripotent stem cell, TDP-43, Protein TDP-43, General Engineering, oligodendrocytes, Biology, medicine.disease_cause, medicine.disease, DNA-binding protein, Cell biology, chemistry.chemical_compound, chemistry, Transactive memory, medicine, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Gene, DNA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d6d6e844edbdfe4e1fb94d4ced1ab0
https://www.pure.ed.ac.uk/ws/files/260345909/fcab255.pdf

المؤلفون: Mary Porteous, Danielle Leighton, Jon Warner, Siddharthan Chandran, Andrew M. McIntosh, Elaine M. Cleary, Sharon Abrahams, Suvankar Pal, Caroline A. McHutchison

المصدر: McHutchison, C A, Leighton, D J, McIntosh, A, Cleary, E, Warner, J, Porteous, M, Chandran, S, Pal, S & Abrahams, S 2020, ' Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND ', Journal of Neurology, Neurosurgery & Psychiatry, vol. 91, no. 3, pp. 245-253 . https://doi.org/10.1136/jnnp-2019-321737

مصطلحات موضوعية: cognition, Male, amyotrophic lateral sclerosis, medicine.medical_specialty, Databases, Factual, Population, frontotemporal dementia, motor neurone disease, 03 medical and health sciences, 0302 clinical medicine, medicine, Dementia, Verbal fluency test, Humans, Apathy, Cognitive Dysfunction, Family history, Motor Neuron Disease, education, Psychiatry, 030304 developmental biology, Aged, Retrospective Studies, 0303 health sciences, education.field_of_study, business.industry, Mental Disorders, Middle Aged, medicine.disease, behaviour, neuropsychiatric disorders, Psychiatry and Mental health, Mood disorders, Scotland, Frontotemporal Dementia, Surgery, Female, Neurology (clinical), medicine.symptom, business, Motor neurone disease, 030217 neurology & neurosurgery, Frontotemporal dementia

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2b392c8dc73ed0841d2c7d10c48f01
https://pubmed.ncbi.nlm.nih.gov/31871139

المؤلفون: Suvankar Pal, Tara Azam, Robert Swingler, Jon Warner, Laura Stephenson, Shuna Colville, David Moore, Siddharthan Chandran, Mary Porteous, George Gorrie, Elaine M. Cleary

المصدر: Cleary, E M, Pal, S, Azam, T, Moore, D J, Swingler, R, Gorrie, G, Stephenson, L, Colville, S, Chandran, S, Porteous, M & Warner, J P 2016, ' Improved PCR based methods for detecting C9orf72 hexanucleotide repeat expansions ', Molecular and Cellular Probes . https://doi.org/10.1016/j.mcp.2016.06.001
Molecular and Cellular Probes

مصطلحات موضوعية: 0301 basic medicine, Genetic testing, Pcr assay, Combined use, Biology, Polymerase Chain Reaction, Sensitivity and Specificity, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, C9orf72, Humans, Base sequence, Molecular Biology, Alleles, Polymerase chain reaction, DNA Primers, Genetics, DNA Repeat Expansion, Base Sequence, C9orf72 Protein, Mosaicism, Amyotrophic Lateral Sclerosis, Proteins, Cell Biology, Repeat-primed PCR, 3. Good health, 030104 developmental biology, Scotland, Mutation, Artifacts, Trinucleotide repeat expansion, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a57c07f9ca613416864434b460cdf81

المؤلفون: Sanziana Rotariu, Thomas H. Gillingwater, Judith Newton, Siddharthan Chandran, Colin Smith, Elaine M. Cleary, Christine A. F. von Arnim, Danielle Leighton, Jon Warner, Tara L. Spires-Jones, Dimitrios I Sideris, Makis Tzioras, Dorothée Lulé, Robert Swingler, Chris-Anne McKenzie, Albert C. Ludolph, Emily Carroll, Sharon Abrahams, Sally Salomonsson, Christopher M. Henstridge

المصدر: Henstridge, C M, Sideris, D I, Carroll, E, Rotariu, S, Salomonsson, S, Tzioras, M, McKenzie, C-A, Smith, C, von Arnim, C A F, Ludolph, A C, Lulé, D, Leighton, D, Warner, J, Cleary, E, Newton, J, Swingler, R, Chandran, S, Gillingwater, T H, Abrahams, S & Spires-Jones, T L 2018, ' Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis ', Acta Neuropathologica, vol. 135, no. 2, pp. 213-226 . https://doi.org/10.1007/s00401-017-1797-4
Acta Neuropathologica

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Prefrontal Cortex, Disease, Neuropathology, Pathology and Forensic Medicine, Synapse, Cohort Studies, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Atrophy, Journal Article, Medicine, Humans, Cognitive Dysfunction, Amyotrophic lateral sclerosis, Cognitive decline, Phosphorylation, Prefrontal cortex, Aged, Aged, 80 and over, Original Paper, business.industry, Amyotrophic Lateral Sclerosis, Cognition, Middle Aged, medicine.disease, DNA-Binding Proteins, 030104 developmental biology, Synapses, Female, Neurology (clinical), business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84638ff2b8aaa1b3d1c9e77fdd16a679
https://www.pure.ed.ac.uk/ws/files/50603954/10.1007_2Fs00401_017_1797_4.pdf

المؤلفون: Anna-Claire Devlin, Karen Burr, Shyamanga Borooah, Joshua D. Foster, Elaine M. Cleary, Imbisaat Geti, Ludovic Vallier, Christopher E. Shaw, Siddharthan Chandran, Gareth B. Miles

المصدر: Nature, Nature Communications. 6(1):1-12

الإتاحة: https://ideas.repec.org/a/nat/natcom/v6y2015i1d10.1038_ncomms6999.html

المؤلفون: Holly A. Black, Danielle Leighton, Siddharthan Chandran, George Gorrie, Elaine Rose, Elaine M. Cleary, Robert Swingler, Jon Warner, David A. Ross, Matthew B. Harms, David Goldstein, Laura Stephenson, Timothy J. Aitman, Peter Connick, Suvankar Pal, Mary Porteous, Shuna Colville

المصدر: Neurobiology of Aging

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Aging, Adolescent, Genotype, TBK1, Population, Disease, Protein Serine-Threonine Kinases, Biology, Young Adult, 03 medical and health sciences, medicine, Humans, Genetic Report Abstract, Genetic Predisposition to Disease, Motor neuron disease, Age of Onset, education, Genetic Association Studies, Aged, Aged, 80 and over, education.field_of_study, General Neuroscience, Genetic Variation, Middle Aged, Motor neuron, Amyotrophic lateral sclerosis, NEK1, NIMA-Related Kinase 1, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Scotland, Genetic epidemiology, Female, Neurology (clinical), Geriatrics and Gerontology, Corrigendum, Neuroscience, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d681fb7de803fec5e67b4ec508eaaabb
https://pubmed.ncbi.nlm.nih.gov/28089114