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1دورية أكاديمية
المؤلفون: Tatyana Gurlo, Thazha P. Prakash, Zhongying Wang, Maani Archang, Lina Pei, Madeline Rosenberger, Elaine Pirie, Richard G. Lee, Peter C. Butler
المصدر: Frontiers in Molecular Biosciences, Vol 10 (2023)
مصطلحات موضوعية: islet amyloid polypeptide (IAPP), antisense oligonucleotide (ASO), glucagon-like peptide 1 (GLP-1), islet, diabetes, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Elaine Pirie, Shayoni Ray, Calvin Pan, Wuxia Fu, Andrew F Powers, Danielle Polikoff, Colton M Miller, Katrina M Kudrna, Edward N Harris, Aldons J Lusis, Rosanne M Crooke, Richard G Lee
المصدر: PLoS Genetics, Vol 14, Iss 10, p e1007732 (2018)
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Tomohiro Nakamura, Olga A. Prikhodko, Elaine Pirie, Saumya Nagar, Mohd Waseem Akhtar, Chang-Ki Oh, Scott R. McKercher, Rajesh Ambasudhan, Shu-ichi Okamoto, Stuart A. Lipton
المصدر: Neurobiology of Disease, Vol 84, Iss , Pp 99-108 (2015)
مصطلحات موضوعية: Nitrosative stress, Nitric oxide, Reactive nitrogen species, S-Nitrosylation, Protein misfolding, Mitochondrial dysfunction, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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المؤلفون: Punit P. Seth, Johan Broddefalk, Patrik U. Andersson, Johan Meuller, Michael E. Østergaard, Thazha P. Prakash, Linda Sundström, Leonardo De Maria, Wuxia Fu, Ahlke Hayen, David Janzén, Carina Ämmälä, Eric Valeur, Laurent Knerr, Maria Ölwegård-Halvarsson, Richard G. Lee, Shalini Andersson, William J. Drury, Elaine Pirie, Mehran Nikan, Rasmus Jansson-Löfmark
المصدر: Journal of the American Chemical Society. 143:3416-3429
مصطلحات موضوعية: Agonist, medicine.drug_class, Peptide, 010402 general chemistry, 01 natural sciences, Biochemistry, Glucagon-Like Peptide-1 Receptor, Catalysis, Structure-Activity Relationship, Colloid and Surface Chemistry, In vivo, Insulin-Secreting Cells, medicine, Animals, Humans, Amino Acid Sequence, RNA, Messenger, Receptor, Peptide sequence, chemistry.chemical_classification, Drug Carriers, Molecular Structure, Oligonucleotide, HEK 293 cells, General Chemistry, Oligonucleotides, Antisense, Islet Amyloid Polypeptide, 0104 chemical sciences, Mice, Inbred C57BL, HEK293 Cells, chemistry, Cancer research, Beta cell, Peptides
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المؤلفون: Aldonis J Lusis, Wuxia Fu, Sebastien A. Burel, Richard G. Lee, Padma Narayanan, Jill Hsiao, Patrick Cauntay, Calvin Pan, Elaine Pirie, Rosanne M. Crooke, Shayoni Ray
المصدر: Nucleic Acid Therapeutics. 29:266-277
مصطلحات موضوعية: 0301 basic medicine, Oligonucleotide, food and beverages, Inflammation, Genome-wide association study, Biology, Biochemistry, Genetic architecture, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Drug Discovery, Antisense oligonucleotides, Expression quantitative trait loci, Genetics, medicine, Cancer research, Molecular Medicine, Macrophage, medicine.symptom, Molecular Biology, B cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf5e6576d8062be011e42cc45b4324dd
https://doi.org/10.1089/nat.2019.0797 -
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المؤلفون: Swagata Ghatak, Tomohiro Nakamura, Xu Zhang, Stuart A. Lipton, Piotr Cieplak, Xuemei Han, Chang-ki Oh, John R. Yates, Henry R. Scott, Fernando J. Martinez, Gene W. Yeo, Amanda K. Deal, Elaine Pirie
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Induced Pluripotent Stem Cells, Cell, Protein aggregation, Biology, Nitric Oxide, medicine.disease_cause, CREB, Protein Aggregation, Pathological, Stress, Physiological, mental disorders, medicine, Humans, Cysteine, RNA Processing, Post-Transcriptional, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Motor Neurons, Mutation, S-Nitrosothiols, Multidisciplinary, Amyotrophic Lateral Sclerosis, Neurotoxicity, Brain, nutritional and metabolic diseases, S-Nitrosylation, Biological Sciences, medicine.disease, Reactive Nitrogen Species, nervous system diseases, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Frontotemporal Dementia, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b8306a5c570747fd63e7d61865e592
https://doi.org/10.1073/pnas.2021368118 -
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المؤلفون: Adam E. Mullick, Andrew F. Powers, Rosanne M. Crooke, Elaine Pirie, Richard T. Lee, Thazha P. Prakash, Wuxia Fu, Sue Murray
المصدر: Diabetes. 69
مصطلحات موضوعية: Cyclin-dependent kinase 1, Cyclin D1, Cyclin E2, Cyclin D2, Chemistry, Cell growth, Endocrinology, Diabetes and Metabolism, Internal Medicine, Cancer research, Beta cell, Cell cycle, Receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecda7438563ca80ca41b3d0ffe4793b9
https://doi.org/10.2337/db20-2066-p -
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المؤلفون: Ryan T. Libby, Stuart J Rabin, Ruth Wang, Elaine Pirie, Ranjan Batra, Florian Krach, Anthony Q. Vu, Zacharias Kohl, John Ravits, Gene W. Yeo, Emily C. Wheeler, Michael Baughn, Kasey R. Hutt, María Jesús Delgado Rodríguez, Sandra Diaz-Garcia, Jennifer E. Stauffer, Shahram Saberi, Beate Winner, Assael A. Madrigal
المصدر: Acta neuropathologica, vol 136, iss 3
مصطلحات موضوعية: Male, 0301 basic medicine, Motor neuron, Pathology, TDP-43, Neurodegenerative, Transcriptome, 0302 clinical medicine, Gene expression, 80 and over, 2.1 Biological and endogenous factors, Gene-expression, Phosphorylation, Aetiology, Amyotrophic lateral sclerosis, Aged, 80 and over, Motor Neurons, Casein Kinase I, Neurodegeneration, Laser capture microdissection, Middle Aged, 3. Good health, DNA-Binding Proteins, Spinal Cord, CSNK1E, Neurological, Female, Casein kinase 1, Casein kinase, Biotechnology, medicine.medical_specialty, Clinical Sciences, and over, Biology, Article, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Rare Diseases, Clinical Research, parasitic diseases, Genetics, medicine, Humans, Aged, Messenger RNA, Neurology & Neurosurgery, Amyotrophic Lateral Sclerosis, Sporadic disease, Human Genome, Neurosciences, medicine.disease, Brain Disorders, Gene expression profiling, Orphan Drug, 030104 developmental biology, RNA, Neurology (clinical), ALS, RNA-seq, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Elaine, Pirie, Patrick, Cauntay, Wuxia, Fu, Shayoni, Ray, Calvin, Pan, Aldonis J, Lusis, Jill, Hsiao, Sebastien A, Burel, Padma, Narayanan, Rosanne M, Crooke, Richard G, Lee
المصدر: Nucleic Acid Ther
مصطلحات موضوعية: Inflammation, CCAAT-Enhancer-Binding Protein-beta, Gene Expression Profiling, Oligonucleotides, Antisense, Protein Serine-Threonine Kinases, Polymorphism, Single Nucleotide, Original Papers, Cell Line, Mice, Animals, Humans, Genetic Predisposition to Disease, Chemokine CCL4, Transcriptome, Chemokine CCL2, Genome-Wide Association Study
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::aa5fc5522a7263e993c01496f995593c
https://pubmed.ncbi.nlm.nih.gov/31368839 -
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المؤلفون: Rosanne M. Crooke, Elaine Pirie, Andrew F. Powers, Richard T. Lee, Sue Murray, Wuxia Fu, Thazha P. Prakash
المصدر: Diabetes. 68
مصطلحات موضوعية: 0301 basic medicine, endocrine system, Messenger RNA, geography, geography.geographical_feature_category, Chemistry, Endocrinology, Diabetes and Metabolism, Pancreatic islets, 030209 endocrinology & metabolism, Pharmacology, Islet, KEAP1, Glucagon-like peptide-1, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Internal Medicine, medicine, Beta cell, Receptor, Intracellular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3bdcd22b83217a6e22e8cda3e1a896bc
https://doi.org/10.2337/db19-2143-p