-
1
المؤلفون: Richard E. Showalter, Jim Thomson, Yudou He, Mario Meng-Chiang Kuo, Richard Hickey, Wei-Jong Shia, Li-Chang Chen, Elena Brin, Eleanor Dagostino, Katherine Wu, Robert Almassy, Mariusz Stempniak
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Chemistry, apoptosis, Cancer, TRAIL, medicine.disease, Fusion protein, arginine deiminase, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Apoptosis, anti-cancer biologic, 030220 oncology & carcinogenesis, Cancer cell, Survivin, medicine, Cancer research, fusion protein, Tumor necrosis factor alpha, Receptor, Arginine deiminase, Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920a1fcfc2cf7ef29450ed87d9dde742
http://europepmc.org/articles/PMC6319333 -
2
المؤلفون: Richard E. Showalter, Wei-Jong Shia, Jim Thomson, Elena Brin, Bob Almassy, Eleanor Dagostino, Li-Chang Chen, Richard Hickey, Mario Meng-Chiang Kuo, Katherine Wu, Yudou He
المصدر: Cancer Research. 78:3902-3902
مصطلحات موضوعية: Cancer Research, chemistry.chemical_compound, Oncology, chemistry, Arginine, Apoptosis, In vivo, Cancer cell, Citrulline, Cancer research, Fusion protein, Arginine deiminase, In vitro
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ba05403b029c18e218eec9451a77fafd
https://doi.org/10.1158/1538-7445.am2018-3902 -
3
المؤلفون: Todd VanArsdale, RoseAnn Ferre, David A. Matthews, Ian Popoff, Marakovits Joseph T, Brion W. Murray, Joseph Piraino, Barbara Mroczkowski, Dong Liming, Stephen Margosiak, Xinjun Hou, M. Catherine Johnson, James Arthur Thomson, Gerrit Los, Eleanor Dagostino, Chuangxing Guo, Samantha Elizabeth Greasley, Hans E. Parge
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5613-5616
مصطلحات موضوعية: Molecular model, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Computational biology, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Drug Discovery, Combinatorial Chemistry Techniques, Humans, Structure–activity relationship, Computer Simulation, Amino Acid Sequence, Enzyme Inhibitors, NIMA-Interacting Peptidylprolyl Isomerase, Molecular Biology, Peptidylprolyl isomerase, Binding Sites, Ligand efficiency, Chemistry, Organic Chemistry, Peptidylprolyl Isomerase, Drug Design, Cis-trans-Isomerases, PIN1, Molecular Medicine
-
4
المؤلفون: Li Haitao, Paderes Genevieve Deguzman, Brion W. Murray, Xinjun Hou, RoseAnn Ferre, Marakovits Joseph T, M. Catherine Johnson, Paul S. Humphries, Samantha Elizabeth Greasley, Eugenia Kraynov, Joseph Piraino, Dong Liming, Eleanor Dagostino, Chuangxing Guo
المصدر: Bioorganicmedicinal chemistry letters. 24(17)
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Carboxylic Acids, Pharmaceutical Science, Proline binding, Biochemistry, Epitope, Phosphates, chemistry.chemical_compound, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Humans, Carboxylate, Enzyme Inhibitors, Molecular Biology, Cell permeability, biology, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Active site, Peptidylprolyl Isomerase, Phosphate, NIMA-Interacting Peptidylprolyl Isomerase, chemistry, biology.protein, PIN1, Molecular Medicine, Structure based, Benzimidazoles
-
5
المؤلفون: Ya-Li Deng, Zhang Junhu, Martin Paul Edwards, James G. Christensen, Yang Anle, Lisa C. Guo, Brion W. Murray, Tikhe Jayashree Girish, Kephart Susan Elizabeth, Indrawan James Mcalpine, Marakovits Joseph T, Dong Liming, Li Haitao, Christine Del-Carmen, Tod Smeal, Daniel D. Knighton, Eugenia Kraynov, Paul G. Richardson, Eleanor Dagostino, Chuangxing Guo, Djamal Bouzida, Robert Steven Kania, Joseph Piraino, M. Catherine Johnson, Joseph K. T. Lee
المصدر: Journal of medicinal chemistry. 55(10)
مصطلحات موضوعية: Drug, Models, Molecular, media_common.quotation_subject, Molecular Conformation, Administration, Oral, Antineoplastic Agents, macromolecular substances, Pharmacology, Crystallography, X-Ray, environment and public health, Permeability, Mice, Structure-Activity Relationship, Dogs, In vivo, Drug Discovery, Animals, Humans, Tumor growth, Pyrroles, media_common, Kinase, Chemistry, Hydrogen Bonding, Stereoisomerism, equipment and supplies, Amides, Xenograft Model Antitumor Assays, Rats, Tumor Burden, enzymes and coenzymes (carbohydrates), Orally active, p21-Activated Kinases, Molecular Medicine, Pyrazoles, Efflux, Carbamates, biological phenomena, cell phenomena, and immunity
-
6
المؤلفون: Tod Smeal, Karlicek Shannon Marie, Kephart Susan Elizabeth, Jane Lamerdin, Marakovits Joseph T, Eleanor Dagostino, Chuangxing Guo, Joseph Piraino, John Westwick, Michael Zager, Daniel R. Knighton, Simon Bergqvist, Brion W. Murray, James G. Christensen, Cho-Ming Loi, Ricardo Martinez, Cathy Zhang, Eugenia Kraynov, Ian Popoff
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 107(20)
مصطلحات موضوعية: Models, Molecular, Cell Survival, Biology, Cell Line, Tumor, Neoplasms, Guanine Nucleotide Exchange Factors, Humans, Pyrroles, Phosphorylation, p21-activated kinases, Cell Proliferation, Multidisciplinary, Crystallography, Cell growth, Effector, Kinase, Biological Sciences, Small molecule, Cell biology, p21-Activated Kinases, Cancer research, Pyrazoles, Guanine nucleotide exchange factor, Signal transduction, Rho Guanine Nucleotide Exchange Factors, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1c2a25c2007cf3d3777e2c19b4e847
https://pubmed.ncbi.nlm.nih.gov/20439741 -
7
المؤلفون: Liming Dong, Joseph Marakovits, Xinjun Hou, Chuangxing Guo, Samantha Greasley, Eleanor Dagostino, RoseAnn Ferre, M. Catherine Johnson, Eugenia Kraynov, James Thomson, Ved Pathak, Brion W. Murray
المصدر: Bioorganicmedicinal chemistry letters. 20(7)
مصطلحات موضوعية: Models, Molecular, Binding Sites, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Peptidylprolyl Isomerase, Crystallography, X-Ray, Biochemistry, NIMA-Interacting Peptidylprolyl Isomerase, Structure-Activity Relationship, Drug Design, Drug Discovery, Molecular Medicine, Humans, Enzyme Inhibitors, Molecular Biology, Protein Binding
-
8
المؤلفون: Joseph K. T. Lee, Tikhe Jayashree Girish, Ya‐Li Deng, Joseph Piraino, Li Haitao, Djamal Bouzida, Eleanor Dagostino, Chuangxing Guo, Zhang Junhu, Hasam Younis, Kephart Susan Elizabeth, Brion W. Murray, Indrawan James Mcalpine, Jamie Christensen, Marakovits Joseph T, Tod Smeal, Eugenia Kraynov, Cho-Ming Loi, Lisa Guo, Dan Knighton, Catherine Johnson, Yang Anle, Dong Liming
المصدر: Molecular Cancer Therapeutics. 8:PR-2
مصطلحات موضوعية: Cancer Research, Kinase, Effector, Cell, GTPase, CDC42, Biology, PAK1, medicine.anatomical_structure, Oncology, Biochemistry, Protein kinase domain, In vivo, Cancer research, medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1b220446bd808e97bcb76e7a46d06a11
https://doi.org/10.1158/1535-7163.targ-09-pr-2