-
1
المؤلفون: Tanya Michelle Jewell, Robert Steven Kania, Anand Sistla, Bennett Michael John, Michael R. Gehring, Evan Smith, Zehnder Luke Raymond, Shinji Yamazaki, Karen A. Maegley, Elena Z. Dovalsantos, Ben Burke, Fen Wang, Sacha Ninkovic, Jeff Wang, Joe Zhongxiang Zhou, Pei-Pei Kung, Min-Jean Yin, Michael J. Hickey, Martin James Wythes, Jerry Meng, Buwen Huang, Ping Kang, John F. Braganza, Ketan S. Gajiwala, Tatlock John H, Pramod P. Mehta
المصدر: Journal of Medicinal Chemistry. 54:3368-3385
مصطلحات موضوعية: Pyrimidine, biology, Chemistry, Stereochemistry, medicine.drug_class, Carboxamide, Metabolic stability, Combinatorial chemistry, Hsp90, Bioavailability, chemistry.chemical_compound, Heat shock protein, Drug Discovery, Alkoxy group, biology.protein, medicine, Molecular Medicine, Potency
-
2
المؤلفون: Chunrong Ma, Alan W. Grubbs, Jean Joo Matthews, Steven P. Tanis, Sajiv Krishnan Nair, Erik Jon Flahive, Jim van Wiltenburg, Neal W. Sach, Wolter Ten Hoeve, Elena Z. Dovalsantos, Matt Renner, Cripps Stephan James, Han Koster
المصدر: Tetrahedron Letters. 51:1451-1454
مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Aryl, Organic Chemistry, Ring (chemistry), Biochemistry, chemistry.chemical_compound, chemistry, Heck reaction, Drug Discovery, Lactam, medicine, Sharpless asymmetric dihydroxylation
-
3
المصدر: American Peptide Symposia ISBN: 0792351606
مصطلحات موضوعية: Turn (biochemistry), chemistry.chemical_classification, Steric effects, chemistry.chemical_compound, chemistry, Hydrogen bond, Stereochemistry, Covalent bond, Amide, Peptide, Combinatorial chemistry, Alpha helix, Amino acid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6bfc9cf5790dd4cbfdb4809ec06c43d7
https://doi.org/10.1007/0-306-46862-x_81 -
4
المؤلفون: Hiep T. Luu, Zhen Ping Wu, Theodore O. Johnson, Jia Liu, Bennett Chaplin Borer, Tove Tuntland, Junhua Tao, Caroline A. Lee, Fausto Maldonado, Amy K. Patick, Sylvie K. Sakata, Thomas J. Prins, Naresh K. Nayyar, Rose Ann Ferre, Michael Mohajeri, Peter W. Rose, Maha B. Kosa, David A. Matthews, Kevin Scott Mcgee, Leora S. Zalman, Steven Lee, Peter S. Dragovich, Ellen Y. Wu, Bo Liu, Shella A. Fuhrman, Ye Hua, Elena Z. Dovalsantos, Paul A. Rejto, Ru Zhou, Mark Christopher Guzman, Ming Guo, Edward L. Brown, Minerva R. Batugo, James W. Meador, Lijian Chen, Andreas Liese, Moran Terence Jarold, Jean-Paul R. Gleeson
المصدر: Journal of medicinal chemistry. 46(21)
مصطلحات موضوعية: Male, Magnetic Resonance Spectroscopy, Picornain 3C, Rhinovirus, Peptidomimetic, Stereochemistry, Pyridones, Biological Availability, In Vitro Techniques, Chemical synthesis, Antiviral Agents, Structure-Activity Relationship, Viral Proteins, Dogs, Oral administration, Drug Discovery, Animals, Humans, Protease Inhibitors, chemistry.chemical_classification, biology, 3C Viral Proteases, Biological activity, Blood Proteins, Blood proteins, Cysteine Endopeptidases, Macaca fascicularis, Enzyme, chemistry, Solubility, Enzyme inhibitor, Drug Design, biology.protein, Hepatocytes, Microsomes, Liver, Molecular Medicine, Indicators and Reagents, Caco-2 Cells, Half-Life, Protein Binding