المؤلفون: Khan MM; European Molecular Biology Laboratory, Heidelberg, Germany.; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany., Poeckel D; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany., Halavatyi A; European Molecular Biology Laboratory, Heidelberg, Germany.; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany., Zukowska-Kasprzyk J; European Molecular Biology Laboratory, Heidelberg, Germany., Stein F; European Molecular Biology Laboratory, Heidelberg, Germany., Vappiani J; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany., Sevin DC; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany., Tischer C; European Molecular Biology Laboratory, Heidelberg, Germany., Zinn N; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany., Eley JD; Novel Human Genetics Research Unit, GSK, Stevenage, UK., Gudmann NS; Nordic Bioscience, Herlev, Denmark., Muley T; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Biobank Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany., Winter H; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Biobank Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany., Fisher AJ; Newcastle University Translational and Clinical Research Institute and Institute of Transplantation, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, UK., Nanthakumar CB; Novel Human Genetics Research Unit, GSK, Stevenage, UK., Bergamini G; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.; G. Bergamini and R. Pepperkok contributed equally to this article as lead authors and supervised the work., Pepperkok R; European Molecular Biology Laboratory, Heidelberg, Germany pepperko@embl.de.; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; G. Bergamini and R. Pepperkok contributed equally to this article as lead authors and supervised the work.

المصدر: The European respiratory journal [Eur Respir J] 2021 Jul 01; Vol. 58 (1). Date of Electronic Publication: 2021 Jul 01 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

مواضيع طبية MeSH: Microscopy* , Pulmonary Fibrosis*/pathology, Fibrosis ; Humans ; Lung/pathology ; Proteomics ; Transforming Growth Factor beta1

المؤلفون: Woodcock HV; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Eley JD; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Guillotin D; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Platé M; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Nanthakumar CB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Martufi M; Target Sciences, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Peace S; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Joberty G; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Poeckel D; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Good RB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Taylor AR; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Zinn N; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Redding M; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Forty EJ; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Hynds RE; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, University College London, London, WC1E 6DD, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Swanton C; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, University College London, London, WC1E 6DD, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Karsdal M; Nordic Bioscience, Herlev, 2730, Denmark., Maher TM; Fibrosis Research Group, Inflammation, Repair & Development Section, NHLI, Imperial College, London, SW3 6LY, UK., Fisher A; Newcastle Fibrosis Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Bergamini G; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Marshall RP; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Mercer PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Chambers RC; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK. r.chambers@ucl.ac.uk.

المصدر: Nature communications [Nat Commun] 2020 Sep 11; Vol. 11 (1), pp. 4680. Date of Electronic Publication: 2020 Sep 11.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Good RB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY UK., Eley JD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY UK., Gower E; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY UK., Butt G; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY UK., Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY UK., Fisher AJ; Institute of Transplantation, Newcastle upon Tyne Hospitals NHS Trust and Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle, UK., Nanthakumar CB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY UK.

المصدر: BMC biomedical engineering [BMC Biomed Eng] 2019 Jun 28; Vol. 1, pp. 14. Date of Electronic Publication: 2019 Jun 28 (Print Publication: 2019).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BMC Country of Publication: England NLM ID: 101756092 Publication Model: eCollection Cited Medium: Internet ISSN: 2524-4426 (Electronic) Linking ISSN: 25244426 NLM ISO Abbreviation: BMC Biomed Eng Subsets: PubMed not MEDLINE

المؤلفون: Woodcock HV; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Eley JD; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Guillotin D; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Platé M; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Nanthakumar CB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Martufi M; Target Sciences, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Peace S; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Joberty G; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Poeckel D; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Good RB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Taylor AR; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Zinn N; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Redding M; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Forty EJ; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Hynds RE; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, University College London, London, WC1E 6DD, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Swanton C; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, University College London, London, WC1E 6DD, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Karsdal M; Nordic Bioscience, Herlev, 2730, Denmark., Maher TM; Fibrosis Research Group, Inflammation, Repair & Development Section, NHLI, Imperial College, London, SW3 6LY, UK., Fisher A; Newcastle Fibrosis Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Bergamini G; Cellzome, a GSK Company, Meyershofstrasse 1, 69117, Heidelberg, Germany., Marshall RP; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Mercer PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK., Chambers RC; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Building, University College London, London, WC1E 6JF, UK. r.chambers@ucl.ac.uk.

المصدر: Nature communications [Nat Commun] 2019 Jan 02; Vol. 10 (1), pp. 6. Date of Electronic Publication: 2019 Jan 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Collagen/*biosynthesis , Fibroblasts/*metabolism , Mechanistic Target of Rapamycin Complex 1/*metabolism , Phosphoproteins/*metabolism , Transforming Growth Factor beta1/*metabolism, Cell Cycle Proteins ; Cell Line ; Humans ; Idiopathic Pulmonary Fibrosis/etiology ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Sirolimus ; TOR Serine-Threonine Kinases/metabolism

المؤلفون: Mercer PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Woodcock HV; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Eley JD; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Platé M; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Sulikowski MG; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Durrenberger PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Franklin L; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Nanthakumar CB; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Man Y; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Genovese F; Nordic Bioscience, Herlev, Denmark., McAnulty RJ; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Yang S; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Maher TM; NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK., Nicholson AG; NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK., Blanchard AD; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Marshall RP; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Lukey PT; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Chambers RC; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.

المصدر: Thorax [Thorax] 2016 Aug; Vol. 71 (8), pp. 701-11. Date of Electronic Publication: 2016 Apr 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: British Medical Assn Country of Publication: England NLM ID: 0417353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3296 (Electronic) Linking ISSN: 00406376 NLM ISO Abbreviation: Thorax Subsets: MEDLINE

مواضيع طبية MeSH: Idiopathic Pulmonary Fibrosis/*drug therapy , Phosphatidylinositol 3-Kinases/*metabolism , Protein Kinase Inhibitors/*therapeutic use , Quinolines/*therapeutic use , Sulfonamides/*therapeutic use , TOR Serine-Threonine Kinases/*antagonists & inhibitors, Cell Proliferation ; Clinical Trials as Topic ; Fibroblasts/metabolism ; Humans ; Idiopathic Pulmonary Fibrosis/pathology ; Pyridazines ; Signal Transduction ; Treatment Outcome

المؤلفون: Eley JD, Kelly JH

المصدر: Clinical chemistry [Clin Chem] 1977 Oct; Vol. 23 (10), pp. 1944-5.

نوع المنشور: Letter

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9421549 Publication Model: Print Cited Medium: Print ISSN: 0009-9147 (Print) Linking ISSN: 00099147 NLM ISO Abbreviation: Clin Chem Subsets: MEDLINE

مواضيع طبية MeSH: Renin/*blood, Angiotensin I/blood ; Buffers ; Humans ; Hydrogen-Ion Concentration ; Temperature ; Time Factors

المؤلفون: Eley JD, Kelly JH

المصدر: Clinical chemistry [Clin Chem] 1981 May; Vol. 27 (5), pp. 774-5.

نوع المنشور: Letter

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9421549 Publication Model: Print Cited Medium: Print ISSN: 0009-9147 (Print) Linking ISSN: 00099147 NLM ISO Abbreviation: Clin Chem Subsets: MEDLINE

مواضيع طبية MeSH: Thyroxine/*blood , Triiodothyronine/*blood, Cross Reactions ; Humans ; Radioimmunoassay/methods ; Reagent Kits, Diagnostic ; Reference Standards