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1دورية أكاديمية
المؤلفون: Alok Jaiswal, Prson Gautam, Elina A Pietilä, Sanna Timonen, Nora Nordström, Yevhen Akimov, Nina Sipari, Ziaurrehman Tanoli, Thomas Fleischer, Kaisa Lehti, Krister Wennerberg, Tero Aittokallio
المصدر: Molecular Systems Biology, Vol 17, Iss 3, Pp n/a-n/a (2021)
مصطلحات موضوعية: cancer driver, data integration, multi‐omics data, reproducibility, synthetic lethality, Biology (General), QH301-705.5, Medicine (General), R5-920
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1744-4292
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2دورية أكاديمية
المؤلفون: Lidia Moyano‐Galceran, Elina A Pietilä, S Pauliina Turunen, Sara Corvigno, Elisabet Hjerpe, Daria Bulanova, Ulrika Joneborg, Twana Alkasalias, Yuichiro Miki, Masakazu Yashiro, Anastasiya Chernenko, Joonas Jukonen, Madhurendra Singh, Hanna Dahlstrand, Joseph W Carlson, Kaisa Lehti
المصدر: EMBO Molecular Medicine, Vol 12, Iss 4, Pp n/a-n/a (2020)
مصطلحات موضوعية: chemotherapy, EphA2, GPRC5A, HGSC, resistance, Medicine (General), R5-920, Genetics, QH426-470
وصف الملف: electronic resource
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المؤلفون: Kaiyang Zhang, Okan Gultekin, Elina A Pietilä, Jordi Gonzalez-Molina, Lidia Moyano-Galceran, Kaisa Lehti, Laura Lehtinen, Ulrika Joneborg, Tarja Lamminen, Sanaz Jamalzadeh, Johanna Hynninen, Tomás A Martins, Rainer Lehtonen, Sakari Hietanen, Sampsa Hautaniemi, Joseph W. Carlson, S. Pauliina Turunen, Seija Grénman, Olli Carpén, Katja Kaipio
المساهمون: Research Program in Systems Oncology, Kaisa Irene Lehti / Principal Investigator, INDIVIDRUG - Individualized Drug Therapy, Sampsa Hautaniemi / Principal Investigator, Research Programs Unit, HUSLAB, Biosciences, Faculty Common Matters (Faculty of Medicine), Bioinformatics, Department of Biochemistry and Developmental Biology, Precision Cancer Pathology, Department of Pathology, Olli Mikael Carpen / Principal Investigator
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, endocrine system diseases, INVASION, Cell, General Physics and Astronomy, Apoptosis, Kaplan-Meier Estimate, Metastasis, Transcriptome, Extracellular matrix, 0302 clinical medicine, 3123 Gynaecology and paediatrics, Tumor Microenvironment, Ovarian Neoplasms, Multidisciplinary, Extracellular Matrix, 3. Good health, Gene Expression Regulation, Neoplastic, Crosstalk (biology), medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Collagen, Signal Transduction, Cancer microenvironment, Stromal cell, STROMA, Science, 3122 Cancers, Antineoplastic Agents, Biology, Article, General Biochemistry, Genetics and Molecular Biology, ACTIN, Evolution, Molecular, 03 medical and health sciences, Ovarian cancer, Cell Line, Tumor, EXTRACELLULAR-MATRIX, Cell Adhesion, medicine, Humans, Gene Expression Profiling, Cancer, General Chemistry, medicine.disease, COLLAGEN-VI, Cystadenocarcinoma, Serous, 030104 developmental biology, Drug Resistance, Neoplasm, METASTASIS, CELLS, Cancer research, Cisplatin, Neoplasm Recurrence, Local, RESISTANCE
وصف الملف: application/pdf
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4دورية أكاديمية
المؤلفون: Elina A. Pietilä, Jordi Gonzalez-Molina, Lidia Moyano-Galceran, Sanaz Jamalzadeh, Kaiyang Zhang, Laura Lehtinen, S. Pauliina Turunen, Tomás A. Martins, Okan Gultekin, Tarja Lamminen, Katja K
المصدر: Nature, Nature Communications. 12(1):1-19
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المؤلفون: Prson Gautam, Sanna Timonen, Tero Aittokallio, Yevhen Akimov, Ziaurrehman Tanoli, Krister Wennerberg, Alok Jaiswal, Kaisa Lehti, Elina A Pietilä, Nina Sipari, Thomas Fleischer, Nora Nordström
المساهمون: Institute for Molecular Medicine Finland, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Computational Systems Medicine, Research Program in Systems Oncology, Kaisa Irene Lehti / Principal Investigator, INDIVIDRUG - Individualized Drug Therapy, Research Programs Unit, Department of Clinical Chemistry and Hematology, TRIMM - Translational Immunology Research Program, HUS Comprehensive Cancer Center, Hematologian yksikkö, Organismal and Evolutionary Biology Research Programme, Krister Wennerberg / Principal Investigator, Helsinki Institute for Information Technology, Tero Aittokallio / Principal Investigator, Bioinformatics
المصدر: Molecular Systems Biology, Vol 17, Iss 3, Pp n/a-n/a (2021)
Jaiswal, A, Gautam, P, Pietilä, E A, Timonen, S, Nordström, N, Akimov, Y, Sipari, N, Tanoli, Z, Fleischer, T, Lehti, K, Wennerberg, K & Aittokallio, T 2021, ' Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor ', Molecular Systems Biology, vol. 17, no. 3, e9526, pp. 1-25 . https://doi.org/10.15252/msb.20209526
Molecular Systems Biologyمصطلحات موضوعية: Medicine (General), multi-omics data, Synthetic lethality, computer.software_genre, Mass Spectrometry, 0302 clinical medicine, Databases, Genetic, Molecular Biology of Disease, Genes, Tumor Suppressor, Biology (General), Cancer, 0303 health sciences, Applied Mathematics, Articles, Genomics, 3. Good health, Computational Theory and Mathematics, Meta-analysis, Female, General Agricultural and Biological Sciences, Algorithms, Information Systems, Data integration, QH301-705.5, 3122 Cancers, Breast Neoplasms, Methods & Resources, Computational biology, Biology, Article, General Biochemistry, Genetics and Molecular Biology, cancer driver, 03 medical and health sciences, R5-920, Cell Line, Tumor, medicine, multi‐omics data, Humans, PTEN, data integration, reproducibility, 030304 developmental biology, Modalities, General Immunology and Microbiology, Endometrial cancer, Reproducibility of Results, Epistasis, Genetic, medicine.disease, Omics, synthetic lethality, biology.protein, Synthetic Lethal Mutations, computer, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Kaisa Huhtinen, Kaisa Lehti, Lidia Moyano-Galceran, Päivi M. Ojala, Laura Lehtinen, Seija Grénman, Erika Gucciardo, Katrin Höpfner, Johanna Hynninen, Olli Carpén, Joonas Jukonen, Elina A Pietilä, Sakari Hietanen
المساهمون: CAN-PRO - Translational Cancer Medicine Program, Research Programs Unit, University of Helsinki, INDIVIDRUG - Individualized Drug Therapy, Research Program in Systems Oncology, Kaisa Irene Lehti / Principal Investigator, Department of Pathology, Biosciences, Medicum, HUSLAB, Precision Cancer Pathology, Olli Mikael Carpen / Principal Investigator, Genome-Scale Biology (GSB) Research Program
المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)مصطلحات موضوعية: Serous carcinoma, Cell, INVASION, PROTEIN, Tumour biomarkers, chemistry.chemical_compound, 0302 clinical medicine, Ovarian Neoplasms, 0303 health sciences, Multidisciplinary, Receptor, EphA2, EPH receptor A2, Ephrin-A5, 3. Good health, Up-Regulation, RECEPTORS, medicine.anatomical_structure, GRADE, 030220 oncology & carcinogenesis, Disease Progression, Phosphorylation, Medicine, Female, Signal Transduction, Cell signalling, EXPRESSION, Science, 3122 Cancers, Biology, Article, 03 medical and health sciences, Ovarian cancer, Cell Line, Tumor, medicine, Biomarkers, Tumor, Ephrin, Humans, 030304 developmental biology, SEROUS CARCINOMA, Erythropoietin-producing hepatocellular (Eph) receptor, Tyrosine phosphorylation, medicine.disease, Survival Analysis, REVERSE, chemistry, Cancer research, Neoplasm Recurrence, Local
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39ad10710b66421862d00487465a0ca
https://hdl.handle.net/11250/3043689 -
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المؤلفون: Anna Mykkänen, Minna P. Mustikka, Thomas Grönthal, Elina Maria Pietilä
المساهمون: Small Animal Hospital, Equine and Small Animal Medicine, Helsinki One Health (HOH)
المصدر: Veterinary Ophthalmology
مصطلحات موضوعية: Male, medicine.medical_specialty, Intraocular pressure, Correlation coefficient, 040301 veterinary sciences, Coefficient of variation, HAND-HELD TONOMETERS, Reference range, Eye, 413 Veterinary science, Standard deviation, DISEASE, 0403 veterinary science, 03 medical and health sciences, Tonometry, Ocular, 0302 clinical medicine, Reference Values, Ophthalmology, medicine, Animals, Original Report, Horses, POSITION, Romifidine, equine, rebound tonometer, tonometry, General Veterinary, INTRAOCULAR-PRESSURE MEASUREMENTS, business.industry, 04 agricultural and veterinary sciences, Repeatability, Original Articles, Reference intervals, Tonovet (R), DOGS, XYLAZINE, 030221 ophthalmology & optometry, Tonovet Plus (R), ROMIFIDINE, Female, business, APPLANATION TONOMETERS, Tonovet Plus®, Tonovet®, medicine.drug, intraocular pressure
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2821b7ec669695c16b6d128fdde8f3e4
http://hdl.handle.net/10138/319514 -
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المؤلفون: Yuichiro Miki, Joseph W. Carlson, Elisabet Hjerpe, Lidia Moyano-Galceran, Ulrika Joneborg, Elina A Pietilä, Joonas Jukonen, Hanna Dahlstrand, Sara Corvigno, Daria Bulanova, S. Pauliina Turunen, Twana Alkasalias, Kaisa Lehti, Masakazu Yashiro, A. Chernenko, Madhurendra Singh
المساهمون: INDIVIDRUG - Individualized Drug Therapy, Kaisa Irene Lehti / Principal Investigator, Research Programs Unit, University of Helsinki, HUS Helsinki and Uusimaa Hospital District, Institute for Molecular Medicine Finland
المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 4, Pp n/a-n/a (2020)مصطلحات موضوعية: 0301 basic medicine, Medicine (General), GPRC5A, Cell- och molekylärbiologi, TO-MESENCHYMAL TRANSITION, INVASION, QH426-470, chemotherapy, Metastasis, Receptors, G-Protein-Coupled, DOUBLE-BLIND, chemistry.chemical_compound, 0302 clinical medicine, Tumor Microenvironment, TUMOR-SUPPRESSOR, HETEROGENEITY, Phosphorylation, Cancer, Ovarian Neoplasms, Receptor, EphA2, Articles, 3. Good health, Gene Knockdown Techniques, Molecular Medicine, Female, Signal transduction, medicine.drug, Signal Transduction, 3122 Cancers, Biology, EphA2, Ribosomal Protein S6 Kinases, 90-kDa, Article, MECHANISMS, resistance, 03 medical and health sciences, R5-920, Downregulation and upregulation, Cell Line, Tumor, medicine, Genetics, BREAST-CANCER, Animals, Humans, Cisplatin, Cancer och onkologi, Tyrosine phosphorylation, HGSC, medicine.disease, Carboplatin, 1ST-LINE TREATMENT, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Cancer and Oncology, METASTASIS, Cancer cell, Cancer research, Ovarian cancer, 030217 neurology & neurosurgery, Cell and Molecular Biology, Neoplasm Transplantation
وصف الملف: application/pdf
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المؤلفون: Tero Aittokallio, Elina A Pietilä, Nina Sipari, Sanna Timonen, Ziaurrehman Tanoli, Krister Wennerberg, Prson Gautam, Nora Nordström, Alok Jaiswal, Kaisa Lehti
مصطلحات موضوعية: 0303 health sciences, Modalities, Computational biology, Biology, Omics, computer.software_genre, 3. Good health, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, 030220 oncology & carcinogenesis, Meta-analysis, biology.protein, Profiling (information science), Suppressor, PTEN, Cancer cell lines, computer, 030304 developmental biology, Data integration
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0db876d10d10ed983550050ef8cb5b
https://doi.org/10.1101/2020.01.31.929372 -
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المؤلفون: Elina A Pietilä, Kaisa Lehti, Yulia Sidorova, Arun Kumar Mahato, Tiina Öhman, Leena Yadav, Mart Saarma, Markku Varjosalo, Xiaonan Liu
المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, INDIVIDRUG - Individualized Drug Therapy, Kaisa Irene Lehti / Principal Investigator, Helsinki University Hospital Area, Genome-Scale Biology (GSB) Research Program, Research Programs Unit, Medicum, Mart Saarma / Principal Investigator, Molecular Systems Biology
المصدر: iScience, Vol 23, Iss 2, Pp-(2020)
iScienceمصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, endocrine system diseases, Phosphatase, 02 engineering and technology, Protein tyrosine phosphatase, Interactome, Article, Receptor tyrosine kinase, RPTP-ALPHA, ACTIVATION, 03 medical and health sciences, Neurotrophic factors, KINASE, Glial cell line-derived neurotrophic factor, PHOSPHORYLATION, lcsh:Science, Molecular Biology, neoplasms, CATALYTIC DOMAINS, Cancer, Multidisciplinary, RECEPTOR, IDENTIFICATION, biology, Kinase, PROTOONCOGENE, Biological Sciences, 021001 nanoscience & nanotechnology, Cell biology, BINDING-SITE, 030104 developmental biology, PROTEIN-TYROSINE-PHOSPHATASE, biology.protein, 1182 Biochemistry, cell and molecular biology, Phosphorylation, lcsh:Q, 0210 nano-technology
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