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المؤلفون: Ronan P. Hanley, David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu, Natalie K. Barker, David Dilworth, Taraneh Hajian, Elisa Gibson, Magdalena M. Szewczyk, Peter J. Brown, Dalia Barsyte-Lovejoy, Laura E. Herring, Gang Greg Wang, Jonathan D. Licht, Masoud Vedadi, Cheryl H. Arrowsmith, Lindsey I. James
المصدر: Journal of the American Chemical Society. 145:8176-8188
مصطلحات موضوعية: Colloid and Surface Chemistry, General Chemistry, Biochemistry, Catalysis
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المؤلفون: Marcus A. Cheek, Aiping Dong, Renato Ferreira de Freitas, Dalia Barsyte-Lovejoy, Aliakbar Khalili Yazdi, Jinrong Min, Fengling Li, Victoria Vu, Albina Bolotokova, Lindsey I. James, Jack Greenblatt, Naimee Mehta, Irina K. Popova, David Dilworth, Ming Lei, Raquel Arminda Carvalho Machado, Ronan P Hanley, David Y Nie, Matthieu Schapira, Mengqi Zhou, Elisa Gibson, Cheryl H. Arrowsmith, Michael-Christopher Keogh, Suzanne Ackloo, Matthew R. Marunde, Mona Alqazzaz, Dmitri Kireev, Nathan W. Hall, Peter Brown, Abdellah Allali-Hassani, Sina Kazemzadeh, Edyta Marcon, Tigran M. Abramyan, Dominic D G Owens, Yanli Liu, Magdalena M. Szewczyk, Matthew J. Meiners, Irene Chau, Su Qin, Masoud Vedadi
المصدر: Nat Chem Biol
مصطلحات موضوعية: Gene isoform, Methyltransferase, Nucleolus, Lysine, Methylation, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Histone-Lysine N-Methyltransferase, Cell Biology, Nucleosomes, Chromatin, Cell biology, Repressor Proteins, Histone, Enzyme, Molecular Probes, 030220 oncology & carcinogenesis, biology.protein, Multiple Myeloma, Cell Nucleolus
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المؤلفون: Sumera Perveen, Carlos A. Zepeda-Velázquez, David McLeod, Richard Marcellus, Mohammed Mohammed, Megha Abbey, Deeba Ensan, Dimitrios Panagopoulos, Viacheslav Trush, Elisa Gibson, Aiping Dong, Levon Halabelian, Gennady Poda, Julie Owen, Ahmed Aman, Taira Kiyota, Ahmed Mamai, Cheryl H. Arrowsmith, Peter J. Brown, Matthieu Schapira, Rima Al-awar, Masoud Vedadi
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::44cf4448a4ef25f58c7154a98ab95c5c
https://doi.org/10.1101/2022.01.05.475077 -
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المؤلفون: Stephanie D. Byrum, Fanye Meng, Gang Greg Wang, Elisa Gibson, Weida Gong, Samuel G. Mackintosh, Ling Cai, Dongxu Li, Rick D. Edmondson, Alan J. Tackett, Masoud Vedadi, Aaron J. Storey, Yi-Hsuan Tsai, Chenxi Xu, Jian Jin, H. Ümit Kaniskan, Kwang-Su Park
المصدر: Cell Chem Biol
مصطلحات موضوعية: Pharmacology, biology, Clinical Biochemistry, Proteolysis targeting chimera, Antineoplastic Agents, Amplicon, Biochemistry, Article, Chromatin, Ubiquitin ligase, Cell biology, Leukemia, Myeloid, Acute, Histone, Nuclear receptor, Neoplasms, Drug Discovery, Cancer cell, Gene expression, Proteolysis, biology.protein, Molecular Medicine, Humans, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d6b7c87b4a3facd015b910ede604dc
https://pubmed.ncbi.nlm.nih.gov/35303440 -
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المؤلفون: Jinrong Min, Matthew R. Marunde, Dmitri Kireev, Jack Greenblatt, Ferreira de Freitas R, Tigran M. Abramyan, Cheryl H. Arrowsmith, Peter Brown, Magda Szewczyk, Irene Chau, A. Dong, Kazemzadeh S, Dalia Barsyte-Lovejoy, Ronan P Hanley, Mengqi Zhou, Y. Liu, Michael-Christopher Keogh, Lindsey I. James, Edyta Marcon, Matthieu Schapira, David Dilworth, Ming Lei, Popova Ik, Albina Bolotokova, Marcus A. Cheek, Masoud Vedadi, Elisa Gibson, Suzanne Ackloo, Su Qin, Matthew J. Meiners, Nathan W. Hall, Abdellah Allali-Hassani, Naimee Mehta, Fengling Li
مصطلحات موضوعية: Gene isoform, Mutation, Methyltransferase, biology, Nucleolus, Chemistry, Methylation, medicine.disease_cause, Subcellular localization, Cell biology, Chromatin, Histone, medicine, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e4c6ef23b32f1b09d83b9d0588c0ec9
https://doi.org/10.1101/2021.03.05.433782 -
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المؤلفون: Dalia Barsyte-Lovejoy, Masoud Vedadi, Cheryl H. Arrowsmith, Jinrong Min, Ronan P Hanley, Rima Al-awar, Matthieu Schapira, Lindsey I. James, Renato Ferreira de Freitas, Magdalena M. Szewczyk, Abdellah Allali-Hassani, Naimee Mehta, Fengling Li, Carlos Zepeda-Velázquez, Elisa Gibson, David McLeod, Yanli Liu, Peter Brown, David Dilworth
المصدر: J Med Chem
مصطلحات موضوعية: Models, Molecular, Methyltransferase, Protein domain, Drug Evaluation, Preclinical, Antineoplastic Agents, Crystallography, X-Ray, Ligands, 01 natural sciences, Article, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, Protein Domains, Drug Discovery, Structure–activity relationship, Humans, Computer Simulation, 030304 developmental biology, 0303 health sciences, Virtual screening, biology, Chemistry, Antagonist, Histone-Lysine N-Methyltransferase, Small molecule, 0104 chemical sciences, 3. Good health, Cell biology, Molecular Docking Simulation, Repressor Proteins, 010404 medicinal & biomolecular chemistry, Histone, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor
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المؤلفون: Peter Loppnau, Elisa Gibson, Masoud Vedadi, Matthieu Schapira, Cheryl H. Arrowsmith, Evelyne Lima-Fernandes, Levi L. Blazer, Mohammad S. Eram
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, substrate specificity, Lysine, Mutation, Missense, Biochemistry, Methylation, Serine, Histones, 03 medical and health sciences, Gene Duplication, Histone methylation, Humans, histone modification, histone methylation, Tyrosine, Molecular Biology, PRDM9, biology, epigenetics, zinc finger, Cell Biology, Histone-Lysine N-Methyltransferase, 030104 developmental biology, Histone, HEK293 Cells, Amino Acid Substitution, Mutagenesis, Histone methyltransferase, biology.protein, Enzymology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1144351be53db649355f9a3f3cb86787
http://europepmc.org/articles/PMC4919437 -
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المؤلفون: Chao Xu, Steven Kennedy, Alma Seitova, Fengling Li, Masoud Vedadi, Taraneh Hajian, Cheryl H. Arrowsmith, Elisa Gibson
المصدر: SLAS Discovery. 21:290-297
مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, AlkB, Plasma protein binding, Ligands, Biochemistry, Analytical Chemistry, Radioligand Assay, 03 medical and health sciences, Protein splicing, Drug Discovery, Humans, biology, AlkB Homolog 5, RNA Demethylase, RNA, Methyltransferases, Molecular biology, Kinetics, 030104 developmental biology, biology.protein, Molecular Medicine, Demethylase, Biological Assay, JARID1B, Protein Binding, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8e38d72fb52af202c11fd0cd844ec5
https://doi.org/10.1177/1087057115623264