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1
المؤلفون: Ulla Pentikäinen, Elisa M. Nurminen, Ferenc Fülöp, László Lázár, Marjo Pihlavisto, Olli T. Pentikäinen
المصدر: Journal of Medicinal Chemistry. 54:2143-2154
مصطلحات موضوعية: Monoamine Oxidase Inhibitors, Protein Conformation, Monoamine oxidase, CHO Cells, Molecular Dynamics Simulation, Ligands, Substrate Specificity, Structure-Activity Relationship, Cricetulus, Cricetinae, Drug Discovery, Animals, Humans, Moiety, Hydrazine (antidepressant), Monoamine Oxidase, Binding Sites, Chemistry, Methylation, Adhesion, bacterial infections and mycoses, In vitro, Rats, respiratory tract diseases, Hydrazines, Biochemistry, Molecular Medicine, Amine gas treating, Amine Oxidase (Copper-Containing), Selectivity, Cell Adhesion Molecules
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2
المؤلفون: Elisa M. Nurminen, Thomas P. Stossel, Martin P. Playford, Olli T. Pentikäinen, Sharon L. Milgram, John H. Hartwig, Fumihiko Nakamura
المصدر: Journal of Biological Chemistry. 285:17156-17165
مصطلحات موضوعية: Scaffold protein, congenital, hereditary, and neonatal diseases and abnormalities, Filamins, Molecular Sequence Data, Cystic Fibrosis Transmembrane Conductance Regulator, Immunoglobulins, Biology, medicine.disease_cause, Filamin, Biochemistry, Contractile Proteins, Protein structure, Cricetinae, medicine, Animals, Humans, FLNA, Amino Acid Sequence, Molecular Biology, Peptide sequence, Mutation, Sequence Homology, Amino Acid, Cell Membrane, Microfilament Proteins, Cell Biology, respiratory system, Molecular biology, Actins, Cystic fibrosis transmembrane conductance regulator, Protein Structure, Tertiary, respiratory tract diseases, Cell biology, Solubility, Protein Structure and Folding, Chloride channel, biology.protein, Peptides, Dimerization, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f382b843ccf20ebadd8a1f8f6beaa3c
https://doi.org/10.1074/jbc.m109.080523 -
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المؤلفون: Jari Ylänne, Heikki Takala, Carl G. Gahmberg, Susanna C. Fagerholm, Maarit Takatalo, Maria Aatonen, Elisa M. Nurminen, Tiila R. Kiema, Tomas Strandin, Susanna M. Nurmi
المصدر: Blood. 112:1853-1862
مصطلحات موضوعية: Models, Molecular, Talin, Threonine, animal structures, Filamins, T-Lymphocytes, Static Electricity, Immunology, Integrin, CD18, macromolecular substances, Plasma protein binding, In Vitro Techniques, Filamin, Biochemistry, Jurkat Cells, 03 medical and health sciences, Filamin binding, Contractile Proteins, 0302 clinical medicine, Cell Adhesion, Humans, Protein Interaction Domains and Motifs, Phosphorylation, Cell adhesion, 030304 developmental biology, 0303 health sciences, Binding Sites, biology, Chemistry, Microfilament Proteins, Cell Biology, Hematology, Intercellular Adhesion Molecule-1, Talin binding, Recombinant Proteins, Cell biology, 14-3-3 Proteins, Amino Acid Substitution, CD18 Antigens, Multiprotein Complexes, 030220 oncology & carcinogenesis, biology.protein, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca34bb23200e71f7bd479de107520e12
https://doi.org/10.1182/blood-2007-12-127795 -
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المؤلفون: Elisa M. Nurminen, Eevi M. Lipponen, Joonas Malinen, Minna Karhinen, Minna Hassinen, Anne Martikainen, Nigel Parker, Piia Valonen, Tarja Hannele Tuunanen, Hanna P. Lesch, Achim Müller, Robert Shaw, Seppo Ylä-Herttuala, Kati Heikkilä, Tuula Salonen, Eva Kristiina Rasanen
المصدر: Molecular Therapy. 23:S267-S268
مصطلحات موضوعية: Pharmacology, Computer science, Fixed bed, business.industry, Process development, Viral vector, Biotechnology, Laboratory flask, Scalable system, Drug Discovery, Genetics, Bioreactor, Molecular Medicine, Production (economics), Early phase, Process engineering, business, Molecular Biology
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المؤلفون: László Lázár, Elisa M. Nurminen, Ferenc Fülöp, Ulla Pentikäinen, Zsolt Szakonyi, Marjo Pihlavisto, Olli T. Pentikäinen
المصدر: Journal of medicinal chemistry. 53(17)
مصطلحات موضوعية: Models, Molecular, Substrate Specificities, Quantitative structure–activity relationship, Molecular Conformation, Quantitative Structure-Activity Relationship, Molecular Dynamics Simulation, Ligands, Molecular dynamics, Cricetulus, Cricetinae, Drug Discovery, Animals, Humans, Monoamine Oxidase, Binding Sites, Chemistry, Stereoisomerism, In vitro, respiratory tract diseases, Rats, Monoamine neurotransmitter, Hydrazines, Biochemistry, Docking (molecular), Molecular Medicine, Amine gas treating, Amine Oxidase (Copper-Containing), Cell Adhesion Molecules, VASCULAR ADHESION PROTEIN 1, Protein Binding
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المؤلفون: Mikko Ylilauri, Juha A. E. Määttä, Ulla Pentikäinen, Jarmo Käpylä, Olli T. Pentikäinen, Johanna Ivaska, Elisa M. Nurminen, Elina Mattila, Sanna Niinivehmas
المصدر: Ylilauri, M, Mattila, E, Nurminen, E M, Käpylä, J, Niinivehmas, S P, Määttä, J A, Pentikäinen, U, Ivaska, J & Pentikäinen, O T 2013, ' Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone ', Biochimica et Biophysica Acta: Proteins and Proteomics, vol. 1834, no. 10, pp. 1988-1997 . https://doi.org/10.1016/j.bbapap.2013.07.001
مصطلحات موضوعية: Spermidine, Protein tyrosine phosphatase, Biochemistry, Analytical Chemistry, 0302 clinical medicine, Phosphorylation, Databases, Protein, 0303 health sciences, Protein Tyrosine Phosphatase, Non-Receptor Type 2, biology, Chemistry, Small molecule, 3. Good health, Cell biology, isothermal titration calorimetry, Molecular Docking Simulation, molecular dynamics simulation, 030220 oncology & carcinogenesis, Thermodynamics, Hydrophobic and Hydrophilic Interactions, Protein Binding, Signal Transduction, Cell signaling, integrin, Integrin, Phosphatase, Static Electricity, Biophysics, Antineoplastic Agents, Molecular Dynamics Simulation, ta3111, mitoxantrone, Integrin alpha1beta1, Small Molecule Libraries, 03 medical and health sciences, SDG 3 - Good Health and Well-being, differential scanning fluorimetry, Humans, Binding site, Molecular Biology, 030304 developmental biology, T-cell protein tyrosine phosphatase, ta1182, ta3122, In vitro, Protein Structure, Tertiary, Kinetics, Cytoplasm, biology.protein, Mitoxantrone, Peptides